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CDC HIV/AIDS/Viral Hepatitis/STD/TB Prevention News Update

Glove Powder and HIV Elisa Tests


The Lancet (05/13/89) No. 8646, P. 1082

The results of a recent study of HIV Elisa tests showed that wearing gloves could results in a false negative test result. This conclusion prompted the laboratory at the Alfred I. DuPont Institute of the Nemours Foundation to find out if its test procedures, which it conducts for the Centers for Disease Control, could be similarly affected. Using the DuPont/Biotech HIV Elisa test, the staff compared control samples, handled by workers without gloves, with experimental samples handled by workers wearing gloves containing corn starch. Analysis of results showed no significant difference in extinction values between control and experimental pool 1 or pool 2 positive serum. An increase in the mean extinction value of experimental wells containing negative serum were attributed to large starch grains interfering with light transmission.


Copyright © 1989 -CDC Prevention News Update, Publisher. All rights reserved to Information, Inc., Bethesda, MD. The CDC National Center for HIV, STD and TB Prevention provides the following information as a public service only. Providing synopses of key scientific articles and lay media reports on HIV/AIDS, other sexually transmitted diseases and tuberculosis does not constitute CDC endorsement. This daily update also includes information from CDC and other government agencies, such as background on Morbidity and Mortality Weekly Report (MMWR) articles, fact sheets, press releases and announcements. Reproduction of this text is encouraged; however, copies may not be sold, and the CDC HIV/STD/TB Prevention News Update should be cited as the source of the information. Contact the sources of the articles abstracted below for full texts of the articles.

Information in this article was accurate in May 13, 1989. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.