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Research from Johns Hopkins University School of Medicine in Immunology Provides New Insights


2012 NOV 19 (NewsRx) -- By a News Reporter-Staff News Editor at AIDS Weekly -- Investigators publish new report on Immunology. According to news originating from Baltimore, Maryland, by NewsRx correspondents, research stated, "Highly active antiretroviral therapy (HAART) suppresses HIV-1 replication, transforming the outlook for infected patients. However, reservoirs of replication-competent forms of the virus persist during HAART, and when treatment is stopped, high rates of HIV-1 replication return."

Our news journalists obtained a quote from the research from the Johns Hopkins University School of Medicine, "Recent insights into HIV-1 latency, as well as a report that HIV-1 infection was eradicated in one individual, have renewed interest in finding a cure for HIV-1 infection. Strategies for HIV-1 eradication include gene therapy and hematopoietic stem cell transplantation, stimulating host immunity to control HIV-1 replication, and targeting latent HIV-1 in resting memory CD4(+) T cells."

According to the news editors, the research concluded: "Future efforts should aim to provide better understanding of how to reconstitute the CD4(+) T cell compartment with genetically engineered cells, exert immune control over HIV-1 replication, and identify and eliminate all viral reservoirs."

For more information on this research see: Developing strategies for HIV-1 eradication. Trends In Immunology, 2012;33(11):554-62. (Elsevier -; Trends In Immunology -

The news correspondents report that additional information may be obtained from C.M. Durand, Dept. of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States (see also Immunology).

Keywords for this news article include: Maryland, Genetics, HIV/AIDS, Baltimore, Immunology, RNA Viruses, Retroviridae, United States, HIV Infections, Vertebrate Viruses, Primate Lentiviruses, North and Central America, Viral Sexually Transmitted Diseases.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC


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Information in this article was accurate in November 19, 2012. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.