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CDC HIV/AIDS/Viral Hepatitis/STD/TB Prevention News Update

GLOBAL: Vitamin D Fights Hepatitis B Virus Infection - Study


Food Consumer (07.28.2013) Aids Weekly Plus

A recent study presented evidence that higher levels of vitamin D reduced hepatitis B virus (HBV) levels. Christian M. Lange, a researcher with Germany’s Johann Wolfgang Goethe University Hospital, and colleagues studied 203 people with chronic HBV infection. The study found that patients with elevated vitamin D serum levels consistently had lower HBV levels. The study disclosed that 34 percent of patients had "severe vitamin D deficiency [25(OH)D3 <10ng/mL],” 47 percent had “vitamin D insufficiency [25(OH)D3 =10ng/mL and <20ng/mL],” and 19 percent of the patients had “adequate vitamin D serum levels [25(OH)D3 =20ng/mL].” The study likewise found "hepatitis B early antigen (HBeAg) positive patients had lower 25(OH)D3 serum levels than HBeAg negative patients." Researchers also noted that during seasons when patients had less exposure to sunshine, the body produced lower vitamin D levels, which increased HBV levels. Investigators determined that HBV-infected people should maintain adequate levels of vitamin D. According to the report, earlier studies found that levels of vitamin D serum were not associated with the hepatitis C virus load. The full report, “Low Vitamin D Serum Concentration is Associated with High Levels of Hepatitis B Virus Replication in Chronically Infected Patients,” was published in the journal Hepatology (2013; doi: 10.1002/hep.26488).


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Information in this article was accurate in August 13, 2013. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.