Sexually Transmitted Diseases Vol. 34; No. 8: P. 541-544
"The incidence of HIV and AIDS is growing faster among
individuals 50 and older compared to those under 40," the
authors wrote. The majority of clinical trials concerning
disease treatment have been found to exclude older persons;
the researchers undertook the current study to determine
"whether this bias extends to sexually transmitted disease
(STD) risk-reduction clinical trials published in a wide range
To determine this, the authors conducted a systematic review
of STD risk-reduction clinical trials that were published in
English-language journals included in MEDLINE between Jan. 1,
1994, and Jan. 1, 2005.
The results showed that persons over age 50 were excluded from
73 percent of these trials, while those over 65 were excluded
from 89 percent. In addition, the level of inclusion of older
persons showed no improvement during the 10 years reviewed.
"The pattern of excluding individuals above the age of 50 from
STD risk-reduction clinical trials has persisted even though
AIDS is increasing most rapidly in this age group," the
authors concluded. "Therefore, a need exists to increase older
individuals' representation in these clinical trials."