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Clonotype analysis of human alloreactive T cells: a novel approach to studying peripheral tolerance in a transplant recipient.
Kusaka S; Grailer AP; Fechner JH Jr; Jankowska-Gan E; Oberley T;
May 30, 2000
Unique Identifier : AIDSLINE MED/20126095

The recognition of allo-MHC and associated peptides on the surface of graft-derived APC by host T cells (direct pathway allorecognition) plays an important role in acute rejection after organ transplantation. However, the status of the direct pathway T cells in stable long term transplants remains unclear. To