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[Tuberculosis and human immunodeficiency virus infection: clinical manifestations and performance of diagnostic procedures according to distinct forms of the localization of disease]
Lado Lado FL; Barrio Gomez E; Carballo Arceo E; Cabarcos Ortiz de Barron
June 30, 2000
An Med Interna. 2000 Jan;17(1):13-8. Unique Identifier : AIDSLINE

OBJECTIVES: To analyse the clinical manifestations and performance of the diagnosis methods in tuberculosis (TB) diagnosed in patients with human immunodeficiency virus infection (HIV), according to the location forms of disease (LF). MATERIAL AND METHODS: We revised 80 cases of TB diagnosed in patients with infection by HIV. The data were gathered in relation to TB location, the clinical data and the microbiological and histological diagnosed studies. In the statistic analysis the values p < 0.05 were taken into account. RESULTS: The prevalence of LF was: 1) pulmonary forms (PF) 32 (40%), of which 12 were typical pulmonary (TP) and 20 atypical pulmonary (AP); 2) mixed forms (MF) 21 (26%); 3) extrapulmonary forms (EF) 19 (24%), of which 17 were lymphadenitis; 4) miliary tuberculosis (MT) 8 cases (10%). The prevailing symptoms were: fever (71%) mainly in MF and MT, cough (69%), with less frequency in AP, EF and MT (p < 0.05) and adenomegalies especially in EF and MF. The diagnosis was based on the study of the sputum smears and lymph node. The bacilloscope of the spontaneous sputum was 53% with a minor performance in the AP (p < 0.05), while in lymph node the smear for AFB was positive in 78% cases and caseous granulomas were observed in 87%. CONCLUSIONS: In our study the major confirmed locations were pulmonary and lymph node, the most important clinical symptoms were fever, cough and adenomegalies. The diagnosis was based, in the most of cases, on the microbiologic and histologic examination of bronchial secretion and lymph node samples.

JOURNAL ARTICLE humana: manifestaciones clinicas y rendimiento de procedimientos diagnosticos segun las distintas formas de localizacion de la enfermedad. Adolescence Adult Aged AIDS-Related Opportunistic Infections/*DIAGNOSIS Blotting, Western Comparative Study Diagnosis, Differential English Abstract Enzyme-Linked Immunosorbent Assay Female Human HIV Infections/DIAGNOSIS Lymph Nodes/MICROBIOLOGY Male Middle Age Mycobacterium tuberculosis/ISOLATION & PURIF Sputum/MICROBIOLOGY Tuberculosis/*DIAGNOSIS Tuberculosis, Lymph Node/DIAGNOSIS Tuberculosis, Miliary/DIAGNOSIS Tuberculosis, Pulmonary/DIAGNOSIS