Two children with symptomatic HIV-infection suffered from extended mollusca contagiosa. Intensified antiretroviral therapy including a protease inhibitor, resulted in a decrease of HIV RNA plasma concentration and a dramatic increase of CD4 T cells. Mollusca contagiosa nearly completely disappeared. These cases demonstrated that newly generated CD4 T cells during sufficient antiretroviral treatment have functional abilities. Therefore, sufficient antiretroviral treatment should be offered to HIV infected children with extended mollusca contagiosa before surgical intervention is considered.

JOURNAL ARTICLE antiretroviraler Therapie. Adolescence Anti-HIV Agents/ADMINISTRATION & DOSAGE/*THERAPEUTIC USE AIDS-Related Opportunistic Infections/*DRUG THERAPY Case Report Child CD4-Positive T-Lymphocytes Didanosine/ADMINISTRATION & DOSAGE/THERAPEUTIC USE English Abstract Human HIV Infections/*DRUG THERAPY HIV Protease Inhibitors/ADMINISTRATION & DOSAGE/THERAPEUTIC USE Male Molluscum Contagiosum/*DRUG THERAPY Ritonavir/ADMINISTRATION & DOSAGE/THERAPEUTIC USE Time Factors Zidovudine/ADMINISTRATION & DOSAGE/THERAPEUTIC USE

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