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Fat redistribution in HIV disease.
Rodwell GE; Maurer TA; Berger TG; Department of Dermatology, University
July 30, 2000
J Am Acad Dermatol. 2000 May;42(5 Pt 1):727-30. Unique Identifier :

BACKGROUND: Abnormal distributions of body fat have been reported in association with HIV infection, including cases of both regional loss and gain of fat. OBJECTIVE: We describe the spectrum of abnormal fat distribution in HIV-positive patients. METHODS: Patients were included if they demonstrated a lack of subcutaneous fat in the cheeks in the absence of generalized wasting. Patients were examined fully and photographed, and medical records were reviewed. RESULTS: Fourteen patients were seen. Further abnormalities of body fat distribution were noted in all patients. We found a consistent pattern of fat loss in the cheeks, temples, and extremities as well as fat gain over the neck, upper back, mastoid processes, chest, and visceral abdomen. CONCLUSION: A consistent syndrome of body fat redistribution is seen in HIV-positive patients. A characteristic pattern of fat loss in the cheeks may serve as a specific marker of HIV-related fat redistribution.

JOURNAL ARTICLE Adipose Tissue/*PHYSIOPATHOLOGY Adult Anti-HIV Agents/THERAPEUTIC USE Blood Glucose/ANALYSIS Human HIV Infections/BLOOD/DRUG THERAPY/*PHYSIOPATHOLOGY HIV Seropositivity/PHYSIOPATHOLOGY Lipids/BLOOD Male Middle Age

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