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Ophthalmic findings in patients with acquired immunodeficiency syndrome.
Chiou SH; Liu CY; Hsu WM; Chan YJ; Chou CK; Chung YM; Liu JH; Liu WT;
July 30, 2000
Chung Hua Min Kuo Wei Sheng Wu Chi Mien I Hsueh Tsa Chih. 2000

Ocular manifestations have been reported in up to 60% of individuals infected with human immunodeficiency virus (HIV) in the United States, and it is becoming increasing apparent that these ocular manifestations almost invariably reflect extent of progression of the disease. The prevalence of ocular abnormalities among acquired immunodeficiency syndrome (AIDS) patients in Taiwan has not been reported. In the present study, we examined and followed up the ophthalmic conditions of a total of 274 HIV-infected patients during the period from March 1993 to May 1999. The results show that cotton-wool spots was the most common ocular finding in this series of patients with AIDS, occurring in 22 (32.8%) of 67 AIDS patients. Cytomegalovirus (CMV) retinitis was the most commonly seen opportunistic ocular infection, occurring in 14 (20.8%) of 67 AIDS patients. These findings suggest that AIDS patients should be closely followed for signs of opportunistic ocular disease which may initially be asymptomatic. Close co-operation between the ophthalmologist and the internist is essential to ensure timely therapeutic intervention, which can decrease the risk of further complications including visual impairment and blindness.

JOURNAL ARTICLE Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adolescence Adult Aged Cytomegalovirus Retinitis/ETIOLOGY CD4 Lymphocyte Count Eye Diseases/*COMPLICATIONS Female Human Male Middle Age Retinal Hemorrhage/ETIOLOGY Support, Non-U.S. Gov't