Antiretroviral drugs exhibit significant between-patient pharmacokinetic variability. Over the past years, data have emerged demonstrating a link between antiretroviral drug concentrations and efficacy or side-effects. As a result, the issue of therapeutic drug monitoring for these compounds are arisen; many published studies provided evidence that plasma concentrations contributes to therapeutic response. However, further information must be collected to define more precisely the therapeutic concentrations and the indications of therapeutic drug-monitoring for each drug.

JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL antiretroviraux dans la prise en charge des patients infectes par le virus de l'immunodeficience humaine. Anti-HIV Agents/*BLOOD/PHARMACOKINETICS/THERAPEUTIC USE Dose-Response Relationship, Drug Drug Monitoring/*METHODS English Abstract Human HIV Infections/*BLOOD/*DRUG THERAPY Patient Selection Treatment Outcome

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