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Primary histiocytic dermatoses.
Ringel E; Moschella S
February 28, 1986
Arch Dermatol. 1985 Dec;121(12):1531-41. Unique Identifier : AIDSLINE

The physiology of the histiocyte (macrophage) in health and disease is reviewed briefly. An overview of the so-called primary malignant, pseudomalignant, and benign histiocytic disorders, excluding histiocytosis X, is presented. The malignant histiocytosis with erythrophagocytosis, the pseudomalignant histiocytic diseases (such as sinus histiocytosis with massive lymphadenopathy and regressing atypical histiocytosis), and the solitary lesions with histologic malignant and atypical storiform histiocytosis are described. Two groups of adult histiocytic diseases are reviewed; one is characterized by nonfamilial and familial histiocytic dermatoarthritis and the other by multiple widespread benign lesions, such as xanthoma disseminatum, generalized eruptive histiocytoma, nodular non-X histiocytosis, and various xanthomatous eruptions associated with paraproteinemia. Finally, multiple benign cutaneous histiocytic lesions of childhood, such as juvenile xanthogranuloma and congenital self-healing histiocytosis, are included.

Adult Aged Arthritis/COMPLICATIONS Child Dermatofibroma/PATHOLOGY Diagnosis, Differential Female Fibroma/PATHOLOGY Granuloma/PATHOLOGY *Histiocytes Human Infant Lymph Nodes/PATHOLOGY Lymphatic Diseases/COMPLICATIONS Macrophages Male Middle Age Prognosis *Reticuloendotheliosis/DIAGNOSIS/PATHOLOGY Skin/PATHOLOGY *Skin Diseases/DIAGNOSIS/PATHOLOGY *Skin Neoplasms/DIAGNOSIS/PATHOLOGY Virus Diseases/COMPLICATIONS Xanthogranuloma, Juvenile/PATHOLOGY Xanthomatosis/PATHOLOGY JOURNAL ARTICLE REVIEW