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NLM AIDSLINE
Lymphoma type adult T-cell leukemia--a clinicopathologic study of HTLV related T-cell type malignant lymphoma.
Yamaguchi K; Yoshioka R; Kiyokawa T; Seiki M; Yoshida M; Takatsuki K
August 30, 1986
Hematol Oncol. 1986 Jan-Mar;4(1):59-65. Unique Identifier : AIDSLINE

The clinical and pathological features of T-cell type malignant lymphoma related to human T-cell leukemia virus (HTLV) were investigated in eight patients presenting lymphadenopathy. Biopsy of lymph nodes showed an histology of diffuse non-Hodgkin's lymphoma. All patients were positive for anti-ATLA antibody and HTLV proviral DNA in the lymph node cells. Most patients showed pronounced hypercalcemia and high serum levels of lactic dehydrogenase. All patients died between 3 and 17 months (mean 8 months) after the onset of disease. HTLV-related malignant lymphoma should be added to the spectrum of ATL, being classified as a lymphoma type ATL.

Adult Aged DNA, Viral/ANALYSIS Female Human HTLV-BLV Viruses/GENETICS Lymphoma/MICROBIOLOGY/PATHOLOGY/*PHYSIOPATHOLOGY Male Middle Age Support, Non-U.S. Gov't T-Lymphocytes/PATHOLOGY JOURNAL ARTICLE

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