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[Cytomegalovirus infection as a cause of intestinal perforation]
Dorfler H; Eisenhut C; Geissler K; Remberger K; Goebel FD; Medizinische
June 30, 1988
Klin Wochenschr. 1988 Jan 15;66(2):69-74. Unique Identifier : AIDSLINE

Three male patients with the acquired immunodeficiency syndrome revealed perforations of the intestine (jejunum-ileum; colon ascendens; coecum). The cause was necrosis due to cytomegalovirus infection. The characteristic findings were cytomegalic inclusion bodies in endothelial cells of the capillaries. These lesions caused alterations of the microcirculation. Therefore it seems reasonable to conclude that in these cases necrosis and perforation were due to ischemia. Cytomegalovirus infection must be taken into consideration in any patient with the acquired immunodeficiency syndrome and gastrointestinal ulcerations.

Acquired Immunodeficiency Syndrome/*PATHOLOGY Adult Case Report Cytomegalovirus/ULTRASTRUCTURE Cytomegalovirus Infections/*PATHOLOGY English Abstract Enteritis/*PATHOLOGY Human Inclusion Bodies, Viral/ULTRASTRUCTURE Intestinal Perforation/*PATHOLOGY Intestines/PATHOLOGY Male Middle Age Necrosis Opportunistic Infections/*PATHOLOGY JOURNAL ARTICLE