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Severe exercise hypoxaemia with normal or near normal X-rays: a feature of Pneumocystis carinii infection.
Smith DE; McLuckie A; Wyatt J; Gazzard B; Department of Medicine and
February 28, 1989
Lancet. 1988 Nov 5;2(8619):1049-51. Unique Identifier : AIDSLINE

To find out whether Pneumocystis carinii pneumonia (PCP) can be detected while still in an early phase by the degree of exercise-induced oxygen desaturation, arterial oxygen saturation was measured by continuous pulse oximetry in patients positive for antibody to the human immunodeficiency virus and clinically suspected of having PCP, in patients with other chest diseases, and in controls. Among patients with proven PCP 94% of those with low arterial oxygen pressures (PaO2) showed desaturation on exercise oximetry, as did 80% of those with a normal oxygen pressure at rest, whereas only 10% of patients with other chest disorders and HIV disease showed significant desaturation.

Anoxemia/*ETIOLOGY/RADIOGRAPHY Comparative Study Diagnosis, Differential *Exertion Human Oximetry Pneumonia, Pneumocystis carinii/BLOOD/*COMPLICATIONS/RADIOGRAPHY Time Factors JOURNAL ARTICLE