translation agency

Second infections in AIDS. A new facet to the immune mechanism.
Kelly TA; Laboure College, Boston, MA 02124.
June 30, 1989
Med Hypotheses. 1988 Dec;27(4):253-4. Unique Identifier : AIDSLINE

The lack of secondary infections or the delay in their appearance in immunodeficient individuals (specifically AIDS patients) previously immunized prior to their immune deficit points to an as yet overlooked mechanism in the immune response. It is proposed that on second exposure to the antigen (Ag) there is a unique Ag presentation that alters the Ag in such a way as to induced a state of tolerance.

Acquired Immunodeficiency Syndrome/*COMPLICATIONS/IMMUNOLOGY Antigens/ADMINISTRATION & DOSAGE Human Immune Tolerance Immunization *Models, Biological Opportunistic Infections/*COMPLICATIONS/IMMUNOLOGY JOURNAL ARTICLE