translation agency

NLM AIDSLINE
Suggested links between different types of dementias: Creutzfeldt-Jakob disease, Alzheimer disease, and retroviral CNS infections.
Manuelidis EE; Manuelidis L; Yale University School of Medicine, Section
October 30, 1989
Alzheimer Dis Assoc Disord. 1989 Spring-Summer;3(1-2):100-9. Unique

Several lines of investigation identify common features of Creutzfeldt-Jakob disease, Alzheimer disease, and retroviral CNS infections. We discuss salient neuropathological, genetic, transmission, and transformation properties that suggest there may be common pathways in the pathogenesis of dementias. We also briefly present potential retroviral mechanisms that may be implicated in all of these dementias.

Acquired Immunodeficiency Syndrome/*COMPLICATIONS Alzheimer's Disease/GENETICS/*MICROBIOLOGY/PATHOLOGY Animal Brain Diseases/*ETIOLOGY/PATHOLOGY Creutzfeldt-Jakob Syndrome/GENETICS/*MICROBIOLOGY/PATHOLOGY Human Retroviridae Infections/*PATHOLOGY Support, U.S. Gov't, P.H.S. JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL

www.aegis.org