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Seroprevalence of HIV-1 among selected patients from a sentinal hospital network in the province of Quebec: a pilot study.
Barnard L; Alary M; Joly JR; Fauvel M; Department de Sante
December 30, 1990
Int Conf AIDS. 1990 Jun 20-23;6(2):436 (abstract no. 3139). Unique

OBJECTIVE: To estimate baseline seroprevalence of HIV-1 infection in selected patients from a sentinel hospital network (anonymous, unlinked seroprevalence study), used as proxy of the general population. METHODS: From April to December 1989, sera from subjects attending the outpatient surgery service and from trauma patients (excluding hemophiliacs, IV drug users, homicides and suicides) admitted to 9 hospitals were tested for HIV-1 antibodies when blood was collected for other purposes. Data on test results and demographic variables (year of birth, sex and region of residence) were anonymously collected. All repeatedly positive ELISA were confirmed by RIPA. RESULTS: During the study period, 5,441 sera were collected. Of these, 30% were from patients living in the Montreal area. Median age was 35 years. Males accounted for 45% of tested individuals. Crude seroprevalence was 7.4 per 10,000 (4/5,441). Three adults (2 men and 1 woman) and one child under 15 were seropositive. All positive adults were living in Montreal whereas the child came from another area. After adjustment for age, sex and area of residence (using Quebec distribution according to 1986 census), global seroprevalence was 5.7 per 10,000. For Montreal, seroprevalence was 15.7 per 10,000 and it was 1.2 per 10,000 for the rest of the province. CONCLUSION: HIV-1 infection seems much more frequent in Montreal than outside this city. Study subjects might be at lower risk than the general population. The study will be enlarged to 25,000 sera tested per year for the next 3 years.

Adult Female Hospitals, Military Human *HIV Seroprevalence HIV-1 Male Pilot Projects Quebec/EPIDEMIOLOGY Trauma Centers ABSTRACT