Int Conf AIDS. 1990 Jun 20-23;6(2):428 (abstract no. 3107). Unique
OBJECTIVE: To verify the proficiency of Governmental blood banks
laboratories screening donors for HIV-1 antibody, in the middle of 1989,
an external quality program was initiated, sending a sera panel with
known reactivity, twice a year to 207 blood banks. METHODS: With a serum
of a single donor, positive for HIV-1 antibody, 3 dilutions were
prepared: 1-strongly, 2-moderately and 3-weakly repeatedly reactives. In
addition, we sent 4 negative sera. Results were reported to the CNTS for
evaluation. RESULTS: We have received at the moment 156 reports (75.4%).
False negatives with strongly reactive sera-1 (0.5%). False negatives
with moderately reactive sera-8 (3.9%). False negatives with weakly
reactive sera-12 (5.8%). False positives with negative sera-7 (3.4%).
CONCLUSION: Reagents for screening of HIV antibody presently used in
Mexico seem to perform adequately. False negative in strongly reactive
sera, as well as 2 false negatives with the moderately reactive sera
were due to clerical error, increasing the number of false positives. We
conclude that efforts should be directed to improve laboratory
organization in order to avoid clerical errors.
*Blood Donors False Negative Reactions False Positive Reactions Human
HIV Antibodies/*BLOOD HIV Infections/*EPIDEMIOLOGY HIV-1/IMMUNOLOGY
Mass Screening Mexico/EPIDEMIOLOGY ABSTRACT