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NLM AIDSLINE
Psychiatric disorder in HIV infected gay males.
Rosenberger P; Bornstein R; Nasrallah H; Para M; Fass R; The Ohio State
December 30, 1990
Int Conf AIDS. 1990 Jun 20-23;6(3):180 (abstract no. S.B.378). Unique

OBJECTIVE: The study investigated the presence of lifetime and current psychiatric disorder in two groups of homosexual males: 1) men who were HIV+ but asymptomatic, (N=25), and 2) men with ARC or AIDS (N=17). METHOD: As part of an extensive baseline neuropsychological and psychiatric evaluation, structured diagnostic interviews from which DSM-III-R diagnoses were determined. RESULTS: Seventy-two percent of HIV+ compared to 100% of ARC/AIDS (SCID-R) patients criteria for one or more psychiatric disorder. Sixty percent of HIV+ reported lifetime substance abuse with 8% reporting current abuse. In contrast, 76% of ARC/AIDS reported lifetime substance abuse with 6% reporting current abuse. Forty-four percent of HIV+ reported lifetime affective disorder (i.e., bipolar, major depressive, dysthymic, adjustment disorder with 4% receiving current diagnoses. In contrast, 76% of ARC/AIDS reported lifetime affective disorder with 12% receiving current diagnoses (x2 p less than .025). Both groups reported episodes of affective disorder precipitated by either confirmation of HIV infection or progression of the disease process. Specifically, 8% of HIV+ reported an episode of affective disorder following HIV+ diagnosis, and 29% of ARC/AIDS reported affective episodes following HIV+ diagnosis, ARC diagnosis, or AIDS-related hospitalization. Anxiety disorders were less frequent, with 12% of HIV+ and 6% of ARC/AIDS reporting lifetime anxiety disorders. CONCLUSION: The data suggest that substance abuse and affective disorder are particularly prevalent in HIV infected gay men. Episodes of affective disorder may be precipitated by confirmed progression of disease. In addition, it is possible that previous episodes of depression may have a role in disease progression.

Acquired Immunodeficiency Syndrome/COMPLICATIONS/DIAGNOSIS/ PHYSIOPATHOLOGY/PSYCHOLOGY Affective Disorders/COMPLICATIONS/*DIAGNOSIS Anxiety AIDS-Related Complex/COMPLICATIONS/DIAGNOSIS/PHYSIOPATHOLOGY/ PSYCHOLOGY Depression Homosexuality Hospitalization Human HIV Infections/COMPLICATIONS/PHYSIOPATHOLOGY/*PSYCHOLOGY HIV Seropositivity/COMPLICATIONS/DIAGNOSIS/PHYSIOPATHOLOGY/ PSYCHOLOGY Interviews Male Prevalence Substance Abuse ABSTRACT

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