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Rhinophyma-like cryptococcal infection as an early manifestation of AIDS in a hemophilia B patient.
Mares M; Sartori MT; Carretta M; Bertaggia A; Girolami A; 2nd Chair of
January 30, 1991
Acta Haematol. 1990;84(2):101-3. Unique Identifier : AIDSLINE

A hemophilia B patient, seropositive for HIV antibodies since 1984, came to us in March 1989 with a severe necrotizing lesion of the nose. It was an erythematous lesion and looked like rhinophyma. Microbiological examination of the skin biopsy showed the presence of Cryptococcus neoformans. At the time of the study, the patient was in partial remission after 2 weeks of therapy with fluconazole per os 400 mg/day. He will be treated with the same therapy at maintenance dose (200 mg/day) for a long period.

Acquired Immunodeficiency Syndrome/*COMPLICATIONS Case Report Christmas Disease/*COMPLICATIONS Cryptococcosis/*DIAGNOSIS/DRUG THERAPY/ETIOLOGY Diagnosis, Differential Fluconazole/THERAPEUTIC USE Human Male Middle Age Rhinophyma/*DIAGNOSIS JOURNAL ARTICLE