Ophthalmology. 1990 Oct;97(10):1342-6. Unique Identifier : AIDSLINE
A 29-year-old man with acquired immune deficiency syndrome (AIDS) was
found to have a retinochoroiditis and optic neuritis of his left eye.
Results of fundus examination showed inflammatory and hemorrhagic
retinal lesions consistent with retinitis due to cytomegalovirus
infection. A computed tomographic (CT) scan demonstrated enlargement of
the optic nerve. The eye was enucleated and results of histopathologic
examination showed retinal necrosis with underlying choroiditis and an
optic neuritis. Numerous encysted Toxoplasma gondii organisms were
present in the retina and tachyzoites were present in the optic nerve.
To the authors' knowledge this is the second histologically documented
case of Toxoplasma optic neuritis in a patient with AIDS.
Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adult Animal Case
Report Choroiditis/*COMPLICATIONS/PATHOLOGY/PARASITOLOGY Eye
Enucleation Human Male Optic Nerve/PARASITOLOGY/RADIOGRAPHY Optic
Retinitis/*COMPLICATIONS/PATHOLOGY/PARASITOLOGY Tomography, X-Ray
Computed Toxoplasma/ULTRASTRUCTURE Toxoplasmosis,
Ocular/*COMPLICATIONS/PATHOLOGY JOURNAL ARTICLE