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G.V.H.D.-like eruption in AIDS: a case report.
Bosseray A; Perrillat Y; Brion JP; Leclercq P; Gral N; Reymond JL;
December 30, 1992
Int Conf AIDS. 1992 Jul 19-24;8(3):58 (abstract no. PuB 7056). Unique

Cutaneous eruption in AIDS are frequently misdiagnosed. PATIENTS: A 32 years old woman, drug-addicted, H.I.V. positive since 1986 CDC, stage 4 was hospitalised for a fever (40 degrees C) with disseminated cutaneous eruption. Lesions were lichenified with an oral and nasal erosive aspect. They were more severe on the palms and soles with blistering. Histological analysis demonstrated epidermal hyperplasia and superficial dermal infiltrate with destruction of the basal lamina. RESULTS: Possible etiologies discussed: Drug toxicity; viral infection; generalised lichen planus; G.V.H.D.-like eruption. Clinical presentation and histological findings were in favor of an auto immune disease with clinical improvement under corticotherapy. Apyrexia was obtained but without any result on the eruption. CONCLUSION: We insist on doing cutaneous biopsy for the diagnosis of eruption in AIDS; allowing the most specific treatment, especially in GVHD-like eruption.

Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adult Case Report Female Graft vs Host Disease/COMPLICATIONS/DIAGNOSIS/PATHOLOGY Human Skin Diseases/*COMPLICATIONS/DIAGNOSIS/PATHOLOGY ABSTRACT

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