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NLM AIDSLINE
The diagnosis of tuberculous lymphadenitis in central Africa.
Bem C; Patil PS; University Teaching Hospital, Lusaka, Zambia.
December 30, 1992
Int Conf AIDS. 1992 Jul 19-24;8(3):54 (abstract no. PuB 7035). Unique

OBJECTIVES: To study tuberculous lymphadenitis (TBL): 1) frequency of coexisting HIV infection; 2) clinical presentation; 3) value of needle aspiration and naked eye examination of removed node in diagnosis. METHODS: Prospective study of all adults referred to one surgeon for biopsy of a peripheral lymph node during 1989-90. RESULTS: 289 patients studied--TB lymphadenitis 177, primary HIV lymphadenopathy 72, Kaposi's disease 23. 87.6% of TBL HIV sero+ve. Clinical presentation of TBL: 93.8% generalised lymphadenopathy; 6.2% maximal size of nodes lcm; 28.8% maximal size of nodes 2cm. Aspiration: 29.7% of TBL acid fast bacilli seen on ZN stain; 74.5% of TBL caseation seen on H&E stain. Naked eye examination of transected removed node in TBL: 42.5% visible caseation and another 34.5% visible tuberculomata. CONCLUSION: Tuberculous lymphadenitis may clinically resemble primary HIV nodes. Histology is not essential for diagnosis.

Biopsy, Needle Diagnosis, Differential Human HIV Infections/COMPLICATIONS/DIAGNOSIS Lymph Nodes/PATHOLOGY Prospective Studies Tuberculosis, Lymph Node/COMPLICATIONS/*DIAGNOSIS ABSTRACT

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