Int Conf AIDS. 1993 Jun 6-11;9(1):387 (abstract no. PO-B10-1509). Unique
Intestinal microsporidiosis is a newly recognized cause of diarrhea in
HIV immuno-compromised patients and only few data are available about
the actual pathogenicity and the natural history of the causal parasite.
We reviewed retrospectively 17 cases diagnosed by the presence of E.
bieneusi in the stool between april 1992 and february 1993. All the
patients, except 1, had a previous history of AIDS, the mean CD4-cells
count was 35/mm3 8-184). All were homosexuals except 2 african patients
and 1 heterosexual. Twelve had a diarrhea (more than 3 bowel
movements/day) but in 5 cases (29%), microsporidiosis was asymptomatic.
It was a watery diarrhea in 83% of cases and 67% of the patients
suffered from this diarrhea for 3 months and more. Cryptosporidiosis was
associated in one case. Albendazole (800 mg/day during 1 month) was
given in 7 cases and was effective on the diarrhea in 5 patients.
CONCLUSION: In this study intestinal microsporidiosis was responsible
for a severe chronic watery diarrhea in 71% of cases but was
asymptomatic in 29% of the patients.
*AIDS-Related Opportunistic Infections/DIAGNOSIS *Carrier
State/DIAGNOSIS *Encephalitozoonosis/DIAGNOSIS *Microspora