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Intestinal microsporidiosis in AIDS patients: high percentage of asymptomatic carriers.
Bouchaud O; Houze S; Saada M; Lebras J; Coulaud JP; Infectious and
November 30, 1993
Int Conf AIDS. 1993 Jun 6-11;9(1):387 (abstract no. PO-B10-1509). Unique

Intestinal microsporidiosis is a newly recognized cause of diarrhea in HIV immuno-compromised patients and only few data are available about the actual pathogenicity and the natural history of the causal parasite. We reviewed retrospectively 17 cases diagnosed by the presence of E. bieneusi in the stool between april 1992 and february 1993. All the patients, except 1, had a previous history of AIDS, the mean CD4-cells count was 35/mm3 8-184). All were homosexuals except 2 african patients and 1 heterosexual. Twelve had a diarrhea (more than 3 bowel movements/day) but in 5 cases (29%), microsporidiosis was asymptomatic. It was a watery diarrhea in 83% of cases and 67% of the patients suffered from this diarrhea for 3 months and more. Cryptosporidiosis was associated in one case. Albendazole (800 mg/day during 1 month) was given in 7 cases and was effective on the diarrhea in 5 patients. CONCLUSION: In this study intestinal microsporidiosis was responsible for a severe chronic watery diarrhea in 71% of cases but was asymptomatic in 29% of the patients.

*AIDS-Related Opportunistic Infections/DIAGNOSIS *Carrier State/DIAGNOSIS *Encephalitozoonosis/DIAGNOSIS *Microspora Infections/DIAGNOSIS