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Teleocidins and benzolactams inhibit cell killing by human immunodeficiency virus type 1 (HIV-1).
Endo Y; Ohno M; Hirano M; Fujiwara T; Sato A; Hinuma Y; Shudo K; Faculty
April 30, 1995
Biol Pharm Bull. 1994 Aug;17(8):1147-9. Unique Identifier : AIDSLINE

Teleocidin B-4 and structurally related synthetic benzolactams were found to be potent inhibitors of cell killing by HIV-1. One of the benzolactams, (-)-BL-V8-310, showed a high selectivity index.

Antiviral Agents/*PHARMACOLOGY Cytopathogenic Effect, Viral/*DRUG EFFECTS Dyes Human HIV-1/*DRUG EFFECTS Irritants/*PHARMACOLOGY Lyngbya Toxins/*PHARMACOLOGY Tetrazolium Salts/DIAGNOSTIC USE Thiazoles/DIAGNOSTIC USE Virus Replication/DRUG EFFECTS Viruses/DRUG EFFECTS JOURNAL ARTICLE