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The African AIDS case definition and HIV serology in medical in-patients at Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Ankrah TC; Roberts MA; Antwi P; Atubrah MP; Bawuah PP; Kotoh S;
April 30, 1995
West Afr J Med. 1994 Apr-Jun;13(2):98-101. Unique Identifier : AIDSLINE

In 914 consecutive medical admissions to Komfo Anokye Teaching Hospital, the prevalence of infection with Human Immunodeficiency Virus type I (HIV-I) and Human Immunodeficiency Virus type 2 (HIV-2) was 12.6%. The prevalence in females was twice that found in males. The infection rate was maximum in the age group 25-29 years for females (45%) and 30-34 years for males (29%). There were 7 cases infected with HIV-2 alone, 55 cases infected with HIV-I alone and 53 cases with dual infection. The cases with HIV-2 infection tended to be older than those with HIV-I infection. For detecting HIV seropositivity in our patients the World Health Organization recommended case definition for AIDS in Africa gave a sensitivity of 32%, a specificity of 93% and a positive predictive value of 42%. The case definition gave the highest specificity and positive predictive values when cases of tuberculosis were not included in the analysis.

Adolescence Adult Aged Comorbidity Female Ghana/EPIDEMIOLOGY *Hospitals, Teaching Human HIV Seropositivity/BLOOD/*EPIDEMIOLOGY/VIROLOGY *HIV Seroprevalence *HIV-1 *HIV-2 *Inpatients Male Middle Age Patient Admission *Population Surveillance Sensitivity and Specificity Sex Factors World Health Organization JOURNAL ARTICLE