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Hepatitis B and C infection in HIV-infected Albertans.
Miedzinski L; Reese H; Houston S; Romanowski B; Shafran S; Taylor G;
January 30, 1997
Int Conf AIDS. 1996 Jul 7-12;11(1):170 (abstract no. Mo.C.1673). Unique

Objective: To examine the frequency of hepatitis markers in HIV-infected Albertans and their association with self identified HIV risk factors and ethnicity. Methods: Data base review of 801 patients in Northern Alberta HIV Outpatient Program registry. Results: 333 (42%) patients had markers for hepatitis B - 263 79%) were positive for hepatitis B surface antibody, 62 (19%) had hepatitis B surface antigen, and 48 (14%) hepatitis B core antibody. Seventy-four patients (9%) were hepatitis C antibody positive. Fourty-three patients (5%) had markers of both hepatitis B and hepatitis C. Self-identified principal risk factors for HIV infection within each of the hepatitis positive groups compared to the total HIV population are tabled below. The IVDU group included sexually active individuals.(table: see text) In patients with sexually acquired HIV, only 11/583 (1.9%) had hepatitis C markers compared to 60/162 (37%) of HIV-infected IVDU. 60/74 (81%) of hepatitis C positive HIV-infected patients admitted to IVDU. Though only 11% of the total clinic attenders in whom ethnicity data were available (711) identified as aboriginal, 31% (17/55) of patients with hepatitis C and 12% 37/309) of patients with hepatitis B markers were aboriginal. An aboriginal origin was claimed in 38/134 (28%) of admitted IVDU. Conclusions: In our HIV population hepatitis C overwhelmingly correlated to IVDU.