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Vaginal flora of HIV-infected women.
Giraldo PC; Daniel-Ribeiro AF; Simoes JA; Amaral E; State University of
January 30, 1997
Int Conf AIDS. 1996 Jul 7-12;11(1):164 (abstract no. Mo.C.1637). Unique

Objective: To compare the prevalence of Vaginal Candidiasis, Vaginal Trichomoniasis and Bacterial Vaginosis among HIV+ women, women with AIDS and HIV- women under risk of HIV infection. Methods: A hundred and fifty two women (75 HIV- (group A), 46 HIV+ (group B) and 31 with AIDS (group C) who attended a STD outpatient clinic at State University of Campinas (SP-Brazil) in 1995 were included in this study. All patients went under a gynecological exam when a vaginal smear was obtained for a gram study. Data from gynecological exam and laboratory results were stored and analyzed by Chi-square or Fisher exact tests. Results: Trichomoniasis was found in 4,0% in group, A, 8,7% in group B and 19,3% in group C. Statistic analysis showed significant difference between groups A and C (p= 0,017) but no difference between groups A and B (p= 0,247) or B and C (p= 0,154). Candidiasis was registered in 17,3% of patients in group A, 21,7% in group B and 29,0% in group C, but there was no statistical differences between them (p is greater than 0,1). Bacterial vaginosis was found in 32% of group A, 36,9% in group B and 29,0% in group C and there was no difference among them (p is greater than 0,1). Conclusions: The initial hypothesis of greater prevalence of Candidiasis among AIDS women was not statistically confirmed in this study despite the observed tendency to that. On the other hand a higher prevalence of Trichomoniasis among patients with AIDS may confirm the idea of a greatness in vaginal flora of patients with advanced disease. This may be due not only to the clinical stage of the disease but also to the high drug therapy these patients are usually taking.

*Candidiasis, Vulvovaginal/COMPLICATIONS *HIV Infections/COMPLICATIONS *Trichomonas Infections/COMPLICATIONS *Vagina/MICROBIOLOGY *Vaginosis, Bacterial/COMPLICATIONS