Experimental and theoretical progress in HIV research includes an improved resolution of the spatial heterogeneity and the dynamics (time course and turnover rates) of virus and CD4+ cells. Some of these advances have resulted from the joint work of experimental and theoretical groups, demonstrating that interdisciplinary research can be fruitful.

Acquired Immunodeficiency Syndrome/*ETIOLOGY/IMMUNOLOGY Antigens, Viral CD4-Positive T-Lymphocytes/IMMUNOLOGY Disease Progression Human HIV/*PATHOGENICITY HIV Infections/IMMUNOLOGY Immunodominant Epitopes Lymphoid Tissue/VIROLOGY Support, U.S. Gov't, P.H.S. T-Lymphocytes, Cytotoxic/IMMUNOLOGY JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL

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