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NLM AIDSLINE
CMV, RS-79070: community concern as major drug's development suspended.
James JS; Clearinghouse, AIDS Newsletter Database, P.O. Box 6003,
September 30, 1997
AIDS Treat News. 1997 May 1;(No 270):1-2. Unique Identifier : AIDSLINE

Due to the declining numbers of cytomegalovirus retinitis cases, Hoffmann-La Roche has suspended plans for future Phase III trials of RS-79070, a prodrug of ganciclovir. RS-79070 provides a higher level of ganciclovir in the blood once it is absorbed. Even though this drug may replace ocular implants or intravenous treatments, it cannot be marketed without conducting expensive Phase III clinical trials. It is hoped that results from continuing Phase II trials will revive the possibility of performing Phase III studies.

*Antiviral Agents/THERAPEUTIC USE *Cytomegalovirus Retinitis/DRUG THERAPY *Ganciclovir/THERAPEUTIC USE *Prodrugs/THERAPEUTIC USE

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