Int Conf AIDS. 1998;12:1179 (abstract no. 60980). Unique Identifier :
OBJECTIVE: to estimate the prevalence of HPV-Cervical intraepithelial
neoplasia (CIN) lesions and condylomata in cohort of HIV seropositive
women observed from January 1993 to february 1997. PATIENTS AND METHODS:
Gynecological examination, colposcopy with biopsy and immunological
parameters were performed on 110 women patients consecutively observed.
The mean age was 31.2 yrs; 42 patients were intravenous drug addicts, 63
had heterosexual contacts and 5 were transfused. Out of 63 heterosexual
patients 70% had had only one sexual partner. 48 (43.6%) patients were
on category A; 62 were symptomatic: 35 were on category B and 27 on C.
65/110 patients were under treatment with antiretroviral compounds.
RESULTS: At the time of enrollment HPV-CIN lesions were found in 21/110
patients (19.1%) and condylomata in 12/110 patients (10.9%). CIN I
lesions were present in 6, CIN II in 8 and CIN III in 7 out 21 patients.
18 out of 21 patients were symptomatic (7 on category B and 11 on
category C) and 17/21 reported only one sexual partner. Visual or
colposcopic inspection of genital tract demonstrated that condylomata
were present on vulva (4 patients), portal (6 patients), vagina and anus
(2 patients) respectively. CONCLUSIONS: The prevalence of HPV-CIN
lesions and condylomata in our cohort is in agreement with the data of
other studies, but worthwhile is that in our cohort 71.1% of the
heterosexual women had had only one sexual partner so being considered
not at high risk of HIV infection and HPV-CIN lesions.
MEETING ABSTRACTS Adult Anti-HIV Agents/THERAPEUTIC USE Blood
Transfusion/ADVERSE EFFECTS Cervix
Neoplasms/*COMPLICATIONS/EPIDEMIOLOGY/VIROLOGY Cohort Studies
Condylomata Acuminata/*COMPLICATIONS/EPIDEMIOLOGY/VIROLOGY Female
Human HIV Infections/*COMPLICATIONS/DRUG THERAPY HIV-1
Papillomavirus, Human/ISOLATION & PURIF Prevalence Sexual Partners
Substance Abuse, Intravenous