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Systemic mycobacterioses in AIDS patients as determined by blood cultures on biphasic medium.
Aily DC; Camargo SS; Paro HS; Passos CA; Coelho AG; Sato DN; Shikama ML;
December 30, 1999
Rev Argent Microbiol. 1999 Apr-Jun;31(2):53-7. Unique Identifier :

Bacteremia due to mycobacteria can occur in AIDS patients in whom a rapid diagnosis is extremely important in order to plan a therapeutic conduct. Blood culture of mycobacteria using a biphasic system was set up in the Regional Laboratories of the Adolfo Lutz Institute, SP (Campinas, Ribeirao Preto, Santo Andre, Santos, Sao Jose do Rio Preto and Sorocaba). During a three year period (1994-97), 1521 blood samples were analyzed from 1336 AIDS patients, with CD4+ cell count < 100/ml, hematocrit < 30% and serum albumin concentration < 3.0 g/dl seen in regional outpatient clinics or as inpatients in hospitals. Of the blood samples examined, 9.9% were positive for mycobacteria. The predominant species was Mycobacterium avium complex (MAC) (53.8%) followed by Mycobacterium tuberculosis (28.0%). Mycobacterium xenopi was isolated in one case (0.8%) and in the remaining 17.4% the mycobacteria isolated were not identified. The implementation of blood culture for mycobacteria in our Institute has permitted the laboratory diagnosis of mycobacterial infections, in addition to providing data on the frequency of disseminated mycobacterial disease in AIDS patients in the region.

JOURNAL ARTICLE AIDS-Related Opportunistic Infections/*BLOOD/DIAGNOSIS/ MICROBIOLOGY Bacteremia/*DIAGNOSIS/MICROBIOLOGY Bacteriological Techniques Brazil/EPIDEMIOLOGY Culture Media Human Mycobacteria, Atypical/ISOLATION & PURIF Mycobacterium/*ISOLATION & PURIF Mycobacterium avium Complex Mycobacterium avium-intracellulare Infection/BLOOD/DIAGNOSIS/ MICROBIOLOGY Mycobacterium tuberculosis/ISOLATION & PURIF Mycobacterium Infections/*BLOOD/DIAGNOSIS/EPIDEMIOLOGY/ MICROBIOLOGY Mycobacterium Infections, Atypical/BLOOD/DIAGNOSIS/MICROBIOLOGY Tuberculosis/BLOOD/DIAGNOSIS/MICROBIOLOGY