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NLM AIDSLINE
Study of the aetiologic agents of meningitis in Kumasi, Ghana, with special reference to Cryptococcal neoformans.
Frimpong EH; Lartey RA; Department of Clinical Microbiology, School of
December 30, 1999
East Afr Med J. 1998 Sep;75(9):516-9. Unique Identifier : AIDSLINE

OBJECTIVE: To evaluate the importance of Cryptococcus neoformans, an opportunistic in meningitis, in healthy and HIV infected patients in Kumasi, Ghana. DESIGN: A prospective study; isolating the aetiologic agents of meningitis from cerebrospinal fluid (CSF) using standard methods. SETTING: Kumasi city, Ashanti region of central Ghana. SUBJECTS: One thousand five hundred and seventy patients suspected of meningitis, including 28 HIV infected and AIDS patients. MAIN OUTCOME MEASURE: The pattern and distribution of the main etiologic agents of meningitis in Kumasi, Ghana shown. RESULTS: Of the 1570 CSF samples examined, 1256 (80%) showed no abnormality. Of the 314 (20%) with abnormalities, 147 were bacterial, and 167 diagnosed aseptic. No cryptococcal cells were found. CONCLUSION: There is a paucity of cryptococcal meningitis in Kumasi, Ghana, and it is not recommended to screen routinely for the fungus in meningitis investigations.

JOURNAL ARTICLE Adolescence Adult AIDS-Related Opportunistic Infections/CEREBROSPINAL FLUID/ EPIDEMIOLOGY/*MICROBIOLOGY Child Child, Preschool Cryptococcosis/CEREBROSPINAL FLUID/EPIDEMIOLOGY/*MICROBIOLOGY *Cryptococcus neoformans Female Ghana/EPIDEMIOLOGY Human Infant Male Mass Screening Meningitis, Aseptic/CEREBROSPINAL FLUID/EPIDEMIOLOGY/ *MICROBIOLOGY Meningitis, Bacterial/CEREBROSPINAL FLUID/EPIDEMIOLOGY/ *MICROBIOLOGY Meningitis, Fungal/CEREBROSPINAL FLUID/EPIDEMIOLOGY/*MICROBIOLOGY Prospective Studies Urban Health

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