Nucleosides Nucleotides. 1999 Jun-Jul;18(6-7):1717-8. Unique Identifier
HIV-1 DNA integration is carried out by integrase, a viral protein which
binds to specific sequences located on both extremities of the HIV-1 DNA
LTR. Inhibition of integration was observed with submicromolar
concentrations of mono- or bifunctionalized 11-mer
oligonucleotide-intercalators, which were designed to form an alternate
strand triple helix with the U5 LTR end containing two adjacent purine
tracts on opposite strands 5'-GGAAAATCTCT-3'/3'-CCTTTTAGAGA-5'.
JOURNAL ARTICLE Base Sequence HIV Long Terminal Repeat
HIV-1/*PHYSIOLOGY Oligonucleotides/*PHARMACOLOGY Support, Non-U.S.
Gov't Virus Integration/*DRUG EFFECTS