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NLM AIDSLINE
An autopsy case of primary nodal plasmacytoma associated with Sjogren's syndrome [letter]
Watanabe K; Yatabe Y; Narita M; Ogawa T; Mori N
December 30, 1999
Pathol Int. 1999 Jun;49(6):577-9. Unique Identifier : AIDSLINE

An 81-year-old man with a 1 year history of Sjogren's syndrome and hypergammaglobulinemic purpura was admitted because of high fever and lymphadenopathy. Primary nodal plasmacytoma was suggested from the microscopic and immunohistochemical findings of an inguinal lymph node biopsy specimen. Although chemotherapy achieved a moderate response, the patient died 2 months later from respiratory and cardiac failure. We herein, is described a rare autopsy case of primary nodal plasmacytoma associated with Sjogren's syndrome, in which the clinical course was progressive and Epstein-Barr virus-encoded RNA 1 was positive in a small number of neoplastic plasma cells, showing some difference from previously reported cases.

LETTER JOURNAL ARTICLE Aged Aged, 80 and over Case Report Fatal Outcome Human Lymph Nodes/*PATHOLOGY/VIROLOGY Male Plasma Cells/VIROLOGY Plasmacytoma/CHEMISTRY/COMPLICATIONS/*PATHOLOGY RNA, Viral/ANALYSIS Sjogren's Syndrome/COMPLICATIONS/*PATHOLOGY Tumor Markers, Biological/ANALYSIS

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