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Being Alive
MEDICAL UPDATE: Antisense Drugs
Mark Katz MD and reported by Jim Stoecker
September 5, 1993
Being Alive 1993 Sep 5: 7

The concept of antisense drugs has been around for several years now. These work at the stage of the HIV life cycle at which the virus is making new virus. The drug would introduce something that would bind to the virus so that it could no longer make new viral RNA. By rendering HIV incapable of reproducing, its further spread to the T-cells is stopped.

One antisense drug that has been developed is GEM 91. This has been shown to be a potent inhibitor of HIV in the test tube. Now we hear that clinical trials of GEM 91 are set to begin. We hope to have more news soon.