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AIDS Weekly Plus
Study Data from Elizabeth Glaser Pediatric AIDS Foundation Update Understanding of HIV/AIDS
Staff Writer
December 10, 2012


2012 DEC 10 (NewsRx) -- By a News Reporter-Staff News Editor at AIDS Weekly -- Data detailed on Immune System Diseases and Conditions have been presented. According to news reporting out of Washington, District of Columbia, by NewsRx editors, research stated, "Given that integration of syphilis testing into prevention of mother-to-child transmission of HIV (PMTCT) programs can prevent adverse pregnancy outcomes, this study assessed feasibility and acceptability of introducing rapid syphilis testing (RST) into PMTCT services. RST was introduced into PMTCT programs in Zambia and Uganda."

Our news journalists obtained a quote from the research from Elizabeth Glaser Pediatric AIDS Foundation, "Using a pre-post intervention design, HIV and syphilis testing and treatment rates during the intervention were compared with baseline. In Zambia, comparing baseline and intervention, 12,761 of 15,967 (79.9%) and 11,460 of 11,985 (95.6%) first-time antenatal care (ANC) attendees were tested for syphilis (P < 0.0001), 523 of 12,761 (4.1%) and 1050 of 11,460 (9.2%) women tested positive (P < 0.0001); and 267 of 523 (51.1%) and 1000 of 1050 (95.2%) syphilis-positive women were treated (P < 0.0001), respectively. Comparing baseline and intervention, 7479 of 7830 (95.5%) and 11,151 of 11,409 (97.7%) of ANC attendees were tested for HIV (P < 0.0001) and 1303 of 1326 (98.3%) and 2036 of 2034 (100.1%) of those testing positive received combination antiretroviral drugs or single-dose nevirapine prophylaxis (P < 0.0001). In Uganda, 13,131 of 14,540 (90.3%) women were tested for syphilis during intervention, with 690 of 13,131 (5.3%) positive and 715 of 690 (103.6%) treated. Syphilis baseline data were collected, but not included in analysis, as ANC syphilis testing before the study was not consistently practiced. Comparing baseline and intervention, 6479 of 6776 (95.6%) and 11,192 of 11,610 (96.4%) ANC attendees were tested for HIV (P = 0.0009) and 570 of 726 (78.5%) and 964 of 1153 (83.6%) received combination or single-dose prophylaxis (P = 0.007). In Zambia, 254 of 1050 (24.2%) syphilis-positive pregnant women were HIV-positive and 99 of 690 (14.3%) in Uganda."

According to the news editors, the research concluded: "Integrating RST in PMTCT programs increases screening and treatment for syphilis among HIV-positive pregnant women and does not compromise HIV services."

For more information on this research see: Introduction of Rapid Syphilis Testing Within Prevention of Mother-to-Child Transmission of HIV Programs in Uganda and Zambia: A Field Acceptability and Feasibility Study. Jaids-Journal of Acquired Immune Deficiency Syndromes, 2012;61(3):E40-E46. Jaids-Journal of Acquired Immune Deficiency Syndromes can be contacted at: Lippincott Williams & Wilkins, 530 Walnut St, Philadelphia, PA 19106-3621, USA (see also Immune System Diseases and Conditions).

Our news journalists report that additional information may be obtained by contacting S. Strasser, Elizabeth Glaser Pediat AIDS Fdn, Washington, DC, United States.

Keywords for this news article include: HIV/AIDS, Syphilis, Washington, RNA Viruses, Retroviridae, United States, HIV Infections, Vertebrate Viruses, District of Columbia, Primate Lentiviruses, Opportunistic Infections, North and Central America, Viral Sexually Transmitted Diseases, Immune System Diseases and Conditions

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