2012 DEC 31 (NewsRx) -- By a News Reporter-Staff News Editor at AIDS Weekly -- A new study on Sexually Transmitted Diseases (STDs) is now available. According to news reporting originating from Antwerp, Belgium, by NewsRx correspondents, research stated, "The authors analysed data from female sex workers screened prior to participation in a microbicide trial to examine the association between prevalent vaginal flora abnormalities and HIV infection, with special emphasis on the role of the intermediate vaginal flora (IVF) in this association. Data from the Kampala, Cotonou, Chennai and Mudhol/Jamkhandi sites were analysed."
Our news editors obtained a quote from the research from Institute for Tropical Medicine, "Participants were interviewed and provided blood for HIV and syphilis antibody testing, genital samples for the diagnosis of vaginal flora abnormalities (using Nugent score) and other reproductive tract infections. Log-binomial regression was used to estimate the HIV prevalence ratio (PR) in relation to IVF and bacterial vaginosis (BV). Among 1367 women, BV, IVF and HIV prevalences were 47.6% (95% CI=45.0% to 50.3%), 19.2% (95% CI=17.1% to 21.2%) and 27.0% (95% CI=24.6% to 29.3%), respectively. In multivariate analysis, adjusting for study site, age, years of education, occupation, female sterilisation, oral sex, past history of sexually transmitted infection, gonorrhoea and candidiasis, IVF was significantly associated with HIV infection with a PR similar to that of BV (adjusted PR 1.56 (95% CI=1.22 to 1.98) and 1.48 (95% CI=1.20 to 1.84), respectively). Though the cross-sectional design of the study precludes directional interpretation of the findings, the data do suggest that IVF may be as important as BV in HIV acquisition."
According to the news editors, the research concluded: "The authors recommend prospective research to better understand the association between IVF and HIV acquisition."
For more information on this research see: Intermediate vaginal flora is associated with HIV prevalence as strongly as bacterial vaginosis in a cross-sectional study of participants screened for a randomised controlled trial. Sexually Transmitted Infections, 2012;88(7):545-132. Sexually Transmitted Infections can be contacted at: Bmj Publishing Group, British Med Assoc House, Tavistock Square, London WC1H 9JR, England. (BMJ Publishing Group - group.bmj.com/; Sexually Transmitted Infections - sti.bmj.com/)
The news editors report that additional information may be obtained by contacting F.A. Guedou, Inst Trop Med, Dept. of Microbiol, B-2000 Antwerp, Belgium (see also Sexually Transmitted Diseases (STDs)).
Keywords for this news article include: Europe, Antwerp, Belgium, HIV/AIDS, Syphilis, Gynecology, Candidiasis, RNA Viruses, Retroviridae, HIV Infections, Women's Health, Vertebrate Viruses, Bacterial Vaginosis, Primate Lentiviruses, Opportunistic Infections, Bacterial Infections and Mycoses, Viral Sexually Transmitted Diseases
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