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AIDS Weekly Plus
Findings from Albert Einstein College of Medicine Broaden Understanding of HIV/AIDS
Staff Writer
July 29, 2013


2013 JUL 29 (NewsRx) -- By a News Reporter-Staff News Editor at AIDS Weekly -- Investigators publish new report on Immune System Diseases and Conditions. According to news reporting out of Bronx, New York, by NewsRx editors, research stated, "Antiretroviral (ARV) therapy has prolonged the life expectancy of HIV-infected persons, increasing their risk of age-associated diseases, including atherosclerosis (AS). Decreased risk of AS has been associated with the prevention and control of hypertension (HTN)."

Our news journalists obtained a quote from the research from the Albert Einstein College of Medicine, "We conducted a cohort study of perimenopausal women and older men with or at risk of HIV infection to identify risk factors for incident HTN. Standardized interviews, physical examinations, and laboratory examinations were scheduled at 6-month intervals. Interview data included demographics, medical, family, sexual behaviour and drug use histories, and physical activity. There were 330 women and 329 men eligible for inclusion in the study; 27% and 35% of participants developed HTN during a median follow-up period of 1080 and 1071 days, respectively. In gender-stratified analysis, adjusting for traditional HTN risk factors (age, race, body mass index, smoking, diabetes, family history of HTN, alcohol dependence, physical activity and high cholesterol), HIV infection was not associated with incident HTN in women [hazard ratio (HR) 1.31; 95% confidence interval (CI) 0.56, 3.06] or men (HR 1.67; 95% CI 0.75, 3.74). Among HIV-infected women, although exposure to ARVs was not significantly associated with incident HTN (HR 0.72; 95% CI 0.26, 1.99), CD4 T-cell count was positively associated with incident HTN (HR 1.15 per 100 cells/L; 95% CI 1.03, 1.28). Among physically active HIV-infected men, exposure to ARVs was negatively associated with incident HTN (HR 0.15; 95% CI 0.03, 0.78). HIV infection was not associated with incident HTN in older men or women."

According to the news editors, the research concluded: "This study provides additional evidence supporting a causal relationship between immune function and incident HTN, which warrants further study."

For more information on this research see: Incident hypertension in older women and men with or at risk for HIV infection. HIV Medicine, 2013;14(6):337-346. HIV Medicine can be contacted at: Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell - www.wiley.com/; HIV Medicine - onlinelibrary.wiley.com/journal/10.1111/(ISSN)1468-1293)

Our news journalists report that additional information may be obtained by contacting S.H. Factor, Albert Einstein College of Medicine, Dept. of Epidemiol & Populat Hlth, Bronx, NY 10467, United States (see also Immune System Diseases and Conditions).

Keywords for this news article include: Bronx, New York, HIV/AIDS, RNA Viruses, Hypertension, Retroviridae, United States, HIV Infections, Vertebrate Viruses, Risk and Prevention, Primate Lentiviruses, Cardiovascular Diseases, North and Central America, Viral Sexually Transmitted Diseases, Immune System Diseases and Conditions

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