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AIDS Weekly Plus
Recent Findings from University of North Carolina Has Provided New Information about HIV/AIDS
Staff Writer
August 5, 2013

2013 AUG 5 (NewsRx) -- By a News Reporter-Staff News Editor at AIDS Weekly -- Current study results on Immune System Diseases and Conditions have been published. According to news reporting originating in Chapel Hill, North Carolina, by NewsRx journalists, research stated, "Globally, an estimated 3.4 million children are living with HIV, yet little is known about the effects of HIV and antiretroviral treatment (ART) on the developing brain, and the neurodevelopmental and behavioural outcomes of perinatally HIV-infected (PHIV+) adolescents. We reviewed the literature on neurodevelopmental outcomes in PHIV+ children and adolescents, and summarized the current evidence on behaviour, general cognition, specific domains, hearing and language, school performance and physical disabilities due to neurological problems."

The news reporters obtained a quote from the research from the University of North Carolina, "Evidence suggests that PHIV+ children do not perform as well as controls on general cognitive tests, processing speed and visual -spatial tasks, and are at much higher risk for psychiatric and mental health problems. Children with AIDS-defining diagnoses are particularly at risk for poorer outcomes. A striking finding is the lack of published data specific to the adolescent age group (10-25 years), particularly from resource-constrained countries, which have the highest HIV prevalence. In addition, extreme heterogeneity in terms of timing and source of infection, and antiretroviral experience limits our ability to summarize findings of studies and generalize results to other settings."

According to the news reporters, the research concluded: "Due to the complex nature of the developing adolescent brain, environmental influences and variation in access to ART, there is an urgent need for research on the longitudinal trajectory of neurodevelopment among children and adolescents perinatally infected with HIV, especially in high burden resource-constrained settings."

For more information on this research see: Neurodevelopment in perinatally HIV-infected children: a concern for adolescence. Journal of the International AIDS Society, 2013;16():1-11. Journal of the International AIDS Society can be contacted at: Int Aids Society, Avenue De France 23, Geneva, 1202, Switzerland. (BioMed Central -; Journal of the International AIDS Society -

Our news correspondents report that additional information may be obtained by contacting B. Laughton, University of North Carolina, Dept. of Epidemiol, Chapel Hill, NC, United States (see also Immune System Diseases and Conditions).

Keywords for this news article include: HIV/AIDS, Pediatrics, Chapel Hill, Adolescence, RNA Viruses, Retroviridae, United States, North Carolina, HIV Infections, Vertebrate Viruses, Primate Lentiviruses, North and Central America, Viral Sexually Transmitted Diseases, Immune System Diseases and Conditions

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