1994

AIDS and the surgical team. [sound recording]: [Chicago, Ill.] : The College, [1991] 2 sound cassettes : analog (American College of Surgeons clinitapes) Unique Identifier : AIDSLINE AV/9410724
TB precautions. [videorecording]: Tucson, Ariz. : Medfilms, c1993 1 videocassette (12 min.) : sd., col. ; 1/2 in. + 1 guide (25 p.) Unique Identifier : AIDSLINE AV/9418081; Reeter AK; Jensen R; (Producer) Viewers learn how TB is transmitted; how TB affects the body; the distinction between dormant and active TB; symptoms, diagnosis, and treatment; role of HIV in disease development; risk groups; dangers of admitting patients with undiagnosed TB; purpose and interpretation of the Mantoux skin test; significa
HIV infection : primary care update. [videorecording]: [Oakland, Calif.] : Kaiser Foundation Health Plan, 1993, c1992 1 videocassette (57 min.) : sd., col. ; 1/2 in (Medicine in the nineties) Unique Identifier : AIDSLINE AV/9415333; Wolfe E; Volberding P; Schram N
Annual report.: New York, N.Y : Gay Men's Health Crisis, v. : ill Unique Identifier : AIDSLINE CAT/9417016
[Om HIV och AIDS pa jobbet.] 1. uppl.: Stockholm : Arbetarskyddsnamnden, 1988 94 p. : ill Unique Identifier : AIDSLINE CAT/9403472
[Psychosoziale Betreuung AIDS-Kranker : Situation der Hauptbetroffenengruppen und Moglichkeiten ambulanter Begleitung. Dieser Patient hat AIDS : von der Begleitung und Pflege eines Aidskranken durch die Diakoniestation.]: [Germany] : Diakonisches Werk der Evangelischen Kirche v. Westfalen, [1988?] 100, 4 p (Weltweite Hilfe ; Heft 1/88) Unique Identifier : AIDSLINE CAT/9402159; Koster-Sommer M
[12 ord i aids-debatten.]: [Kobenhavn] : Sundhedsstyrelsen, c1988 19 p Unique Identifier : AIDSLINE CAT/9406990
Impact of AIDS on the Kaiser Permanente Medical Care Program : (Northern California Region).: Region [Springfield, Va.] : U.S. Dept. of Commerce, National Technical Information Service, [1988] v, 45 p. : ill (Series on AIDS-related issues) Unique Identifier : AIDSLINE CAT/9413129
AIDS targeted information : ATIN. Vol. 3, no. 11 (Nov. 1989)-: Baltimore, MD : Williams & Wilkins, 1989- v Unique Identifier : AIDSLINE CAT/9413852
[Immunschwache AIDS : 150 Fragen, 150 Antworten.] 1. Aufl.: Baierbrunn : Wort & Bild Verlag, 1989 236 p., 6 p. of plates : ill (Gesundheit in Wort & Bild ; Bd. 6) Unique Identifier : AIDSLINE CAT/9408058; Vollmer H
[Smittad : aids och den historiska erfarenheten.]: Stockholm : Landstinget forebygger aids, 1989 26 p (Mer insikt, 5) Unique Identifier : AIDSLINE CAT/9407991; Johannisson K
Casual contact and the risk of HIV infection. 2nd ed.: Washington, DC : American Public Health Association, c1989 10 p (APHA/SIA report ; 1) Unique Identifier : AIDSLINE CAT/9416015
Pediatric HIV infection.: Washington, DC : American Public Health Association, c1989 13 p. ill (APHA/SIA report ; 6) Unique Identifier : AIDSLINE CAT/9416018
Public health implications of PCP prophylaxis.: Washington, DC : American Public Health Association, c1989 11 p. : ill (APHA/SIA report ; 5) Unique Identifier : AIDSLINE CAT/9416017
[ANRS information : bulletin de l'Agence nationale de recherches sur le SIDA.]: Paris : ANRS, v Unique Identifier : AIDSLINE CAT/9422557
The:Effectiveness of drug abuse treatment : implications for controlling AIDS/HIV infection.: [Washington, D.C.] : Congress of the U.S., Office of Technology Assessment, U.S. G.P.O. [distributor, 1990] 152 p. : ill (Background paper) Unique Identifier : AIDSLINE CAT/9412946
How has federal research on AIDS/HIV disease contributed to other fields?.: Washington, DC : U.S. Congress, Office of Technology Assessment, [Supt. of Docs., U.S. G.P.O., distributor, 1990] 1 v. (various pagings) : ill (AIDS-related issues ; Staff paper 5) Unique Identifier : AIDSLINE CAT/9413101; Sisk JE
Living positively with AIDS : the AIDS Support Organization (TASO), Uganda. Rev. ed.: London : ActionAid ; Narobi, Kenya : AMREF ; Colchester, U.K. : World in Need, 1990 35 p. : ill (Strategies for hope ; no. 2) Unique Identifier : AIDSLINE CAT/9404840; Hampton J
AIDS management : an integrated approach. 1st ed.: London : ActionAid ; Nairobi, Kenya : AMREF ; Colchester, U.K. : World in Need, 1990 31 p. : ill (Strategies for hope ; no. 3) Unique Identifier : AIDSLINE CAT/9420995; Campbell ID; Williams G
From fear to hope : AIDS care and prevention at Chikankata Hospital, Zambia. 1st ed.: London : ActionAid ; Nairobi, Kenya : AMREF ; Colchester, U.K. : World in Need, 1990 31 p. : ill (Strategies for hope ; no. 1) Unique Identifier : AIDSLINE CAT/9420994; Williams G
Diagnosis & management of STD's, including HIV infection. 2nd ed.: Health Division [Adelaide?] : Public and Environmental Health Division, South Australian Health Commission, 1990 61 p. : ill (Bulletin ; no. 1) Unique Identifier : AIDSLINE CAT/9416351
Illicit drug use and HIV infection. 2nd ed.: Washington, DC : American Public Health Association, c1990 15 p. ill (APHA/SIA report ; 3) Unique Identifier : AIDSLINE CAT/9416016
[Programa para Navarra de prevencion y control del SIDA e infecciones asociadas al VIH.]: Pamplona : Gobierno de Navarra, Departamento de Salud, c1990 84 p. : ill (Programas de salud) Unique Identifier : AIDSLINE CAT/9403278; Perez Jarauta MJ
Public health implications of early intervention in HIV disease.: Washington, DC : American Public Health Association, c1990 15 p. ill (APHA/SIA report ; 7) Unique Identifier : AIDSLINE CAT/9416019
Victorian local government human immuno deficiency virus (HIV) and acquired immuno deficiency syndrome (AIDS) information booklet for councils.: [Melbourne] : Municipal Association of Victoria, [1990] iii, 32 p. : ill Unique Identifier : AIDSLINE CAT/9404860
A:review of studies which have used quantitative methods to evaluate the effectiveness of interventions and programmes implemented to prevent and control AIDS.: Lausanne : Institut universitaire de medecine sociale et preventive, [1991] 59 leaves : ill (Cahiers de recherches et de documentation ; no 57) Unique Identifier : AIDSLINE CAT/9416284; Hausser D
Assessing AIDS/HIV preventive strategies in the general population : final report of the General Population Working Group.: Lausanne : Institut universitaire de medecine sociale et preventive, [1991] 188 p. : ill (Cahiers de recherches et de documentation ; 78) Unique Identifier : AIDSLINE CAT/9416283; Wellings K
Using STD occurence to monitor AIDS prevention : final report of the Working Group on STD Surveillance.: Lausanne : Institut universitaire de medicine sociale et preventive, [1991] 50 leaves, ii, 98 p. : ill (Cahiers de recherches et de documentation ; 77) Unique Identifier : AIDSLINE CAT/9416157; Renton A
Biosafety guidelines for diagnostic and research laboratories working with HIV.: Geneva : World Health Organization, 1991 iv, 28 p. : ill (WHO AIDS series, ISSN 1011-5773 ; 9) Unique Identifier : AIDSLINE CAT/9416064
AIDS prevention for men having sex with men : final report.: Lausanne : Institut universitaire de medecine sociale et preventive, 1991 89 p. : ill (Cahiers de recherches et de documentation ; 75) Unique Identifier : AIDSLINE CAT/9414642; Pollak M
Diffusion and focus in sexual networking : identifying partners and partners' partners.: [Canberra] : Australian National University, [1992] 16 p (Health Transition working paper ; no. 11, 1992) Unique Identifier : AIDSLINE CAT/9405040; Orubuloye IO
AIDSlink : Eastern, Central & Southern Africa.: Central, and Southern Africa at CEDHA Arusha, Tanzania : AIDS Regional Health Promotion Resource Centre for Eastern, Central and Southern Africa at CEDHA, v. : ill Unique Identifier : AIDSLINE CAT/9421090
Health from the hive : honey, bee pollen, bee propolis, royal jelly.: New Canaan, Conn. : Keats Pub., c1992 x, 163 p Unique Identifier : AIDSLINE CAT/9419489; Wade C
[SIDA : paroles intimes et nouvelles donnes.]: Geneve, Suisse : Les Editions IES, c1992 120 p (Annales du Centre de recherche sociale ; no. 30) Unique Identifier : AIDSLINE CAT/9408923; Pralong B
AIDS treatment update.: London : NAM Charitable Trust, v Unique Identifier : AIDSLINE CAT/9417021
Reaching youth in high-risk situations : three approaches.: Washington, D.C. : United States Conference of Mayors, c1992 15 p (HIV education case studies ; no. 5) Unique Identifier : AIDSLINE CAT/9416672; Andriote J; Tagle R
AIDS resource directory.: [Ottawa] : National AIDS Clearinghouse, Canadian Public Health Association, [1992] iv, 22, iv, 22 p Unique Identifier : AIDSLINE CAT/9405162
[AIDS : Zellphysiologie, Pathologie und Therapie.] 1. Aufl.: Essen : Verlag Neuer Weg, 1992 329 p. : ill Unique Identifier : AIDSLINE CAT/9407661; Segal J
[AIDS-preventie in heteroseksuele contacten : risicoinschatting, voornemen en interactie.]: Amsterdam : Swets & Zeitlinger, c1992 155 p. : ill Unique Identifier : AIDSLINE CAT/9408762; Rademakers J
[Diagnostiek en behandeling van volwassenen met een HIV-infectie : een protocollaire benadering.] 2., herziene druk.: Houten Bohn Stafleu Van Loghum, 1992 63 p. : ill Unique Identifier : AIDSLINE CAT/9408749; Danner SA
HIV capsule report.: Washington, DC : United States Conference of Mayors, v Unique Identifier : AIDSLINE CAT/9417025
AIDS in the dental office? : the story of Kimberly Bergalis and Dr. David Acer. 1st ed.: Fruit Heights, UT : I.C. Publications, 1993 vii, 323 p. : ill., ports Unique Identifier : AIDSLINE CAT/9416217; Bergalis K
No time to wait : a complete guide to treating, managing, and living with HIV infection.: New York : Bantam Books, c1993 xvi, 367 p. : ill Unique Identifier : AIDSLINE CAT/9414218; Siano N; Lipsett S
[AIDS : ein klinischer Leitfaden.] 2., neubearbeitete und erw. Aufl.: Stuttgart ; New York : Georg Thieme Verlag, 1993 x, 292 p. : ill Unique Identifier : AIDSLINE CAT/9413977; Dancygier H
Palliative medicine : symptomatic and supportive care for patients with advanced cancer and AIDS.: Melbourne : Asperula, c1993 viii, 421 p. : ill Unique Identifier : AIDSLINE CAT/9420363; Woodruff R
[Pouvoirs contre SIDA : de la transfusion sanguine au depistage : decisions et pratiques en France, Grande-Bretagne et Suede.]: Paris : Seuil, c1993 420 p. : ill (Sociologie / Seuil) Unique Identifier : AIDSLINE CAT/9410481; Setbon M
State of AIDS in New York : January 1993.: New York, N.Y. : Gay Men's Health Crisis, [1993] 11 p. : ill Unique Identifier : AIDSLINE CAT/9412377
[Arzte fur HIV-Pravention : AIDS-Aufklarung Schweiz 1989-1992 : Tatigkeit, Analysen, und Berichte : eine Dokumentation.]: Zurich : AIDS-Aufklarung Schweiz, c1993 114 p. : ill Unique Identifier : AIDSLINE CAT/9412433; April K
[A la vie, a la mort : medecin par temps d'epidemies.]: Paris : Editions du Seuil, c1993 238 p Unique Identifier : AIDSLINE CAT/9416727; Lebas J
Animal models of HIV and other retroviral infections.: Basel ; New York : Karger, 1993 viii, 200 p. : ill Unique Identifier : AIDSLINE CAT/9414524; Racz P; Letvin NL; Gluckman JC
Bridging the gap : a workshop on HIV treatment information dissemination, February 25-26, 1993, Omni Georgetown Hotel, Washington, DC.: [Washington, D.C.? : s.n. 1993?] iv, 77 p Unique Identifier : AIDSLINE CAT/9413636
The:OSHA handbook : interpretive guidelines for the bloodborne pathogen standard.: El Paso, Tex. : Skidmore-Roth Pub., c1993 1 v. (various pagings) Unique Identifier : AIDSLINE CAT/9418338; Goodner B
[Aspects psychosociaux et culturels du SIDA = Psychosoziale und kulturelle Aspekte von AIDS.] 1-: Berne : Editions Staempfli+Cie SA, 1993- v. : ill Unique Identifier : AIDSLINE CAT/9421803
The:Australian national AIDS and injecting drug users questionnaire (ANAIDUS-Q).: [Kensington, N.S.W.?] : National Drug & Alcohol Research Centre, [1993?] i, 24 p Unique Identifier : AIDSLINE CAT/9413616; Darke S
AIDS & TB abstracts from conference proceedings : international coverage of AIDS and tuberculosis.: Atlanta, GA : CW Henderson, c1993- 1 v. (loose-leaf) Unique Identifier : AIDSLINE CAT/9416623; Henderson AD
Capping justice : discriminatory limits on HIV/AIDS health care benefits : a legal & policy analysis.: San Francisco, Calif. : AIDS Legal Referral Panel, [1993] 1 v. (in various pagings) Unique Identifier : AIDSLINE CAT/9413638; Di Donato PA
Facility-based HIV/AIDS education : demonstration project.: Washington, D.C. : Office of Academic Affairs, VA Central Office, Dept. of Veterans Affairs : U.S. G.P.O., [1993] 31 p Unique Identifier : AIDSLINE CAT/9417986; Walsh PL; Craft CA; Sverha S; Affairs
HIV/AIDS prevention : a guide for working with people who are blind or visually impaired.: New York, : AFB Press, c1993 ix, 115 p Unique Identifier : AIDSLINE CAT/9414775; Kapperman G
Living with AIDS : experiencing ethical problems.: Newbury Park : Sage Publications, c1993 xx, 251 p. : ill Unique Identifier : AIDSLINE CAT/9414166; Cameron M
A:Town forum on AIDS : latest advances in HIV/AIDS vaccines and treatments.: Washington, D.C. : Institute for Advanced Studies in Immunology & Aging, c1994 32 p. : ill., ports Unique Identifier : AIDSLINE CAT/9418618
AIDS testing : a comprehensive guide to technical, medical, social, legal, and management issues. 2nd ed.: New York : Springer-Verlag, c1994 xiv, 411 p. : ill Unique Identifier : AIDSLINE CAT/9422860; Schochetman G; George JR
Guide to NIH HIV/AIDS information services : with selected Public Health Service activities.: [Bethesda, Md.] : U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, 1994 22 p. : ill (NIH publication ; no. 94-3731) Unique Identifier : AIDSLINE CAT/9423319
The:AIDS knowledge base : a textbook on HIV disease from the University of California, San Francisco and the San Francisco General Hospital. 2nd ed.: Boston : Little, Brown, c1994 1 v. (various pagings), 12 p. of plates : ill Unique Identifier : AIDSLINE CAT/9423677; Cohen PT; Sande MA; Volberding P
AIDS and neurology.: Edinburgh ; New York : Churchill Livingstone, 1995 viii, 262 p. : ill (Clinical neurology and neurosurgery monographs) Unique Identifier : AIDSLINE CAT/9423785; Harrison MJ; McArthur JC
The:Medical management of AIDS. 4th ed.: Philadelphia : W.B. Saunders, c1995 xxiii, 740 p., [2] p. of plates : ill Unique Identifier : AIDSLINE CAT/9423684; Sande MA; Volberding P
Memory bank for HIV medications.: Boston : Jones and Bartlett Publishers, c1995 xii, 356 p Unique Identifier : AIDSLINE CAT/9423853; Wilkes GM
Infections in immunocompromised infants and children.: Infections in Immunocompromised Infants and Children. Patrick CC, ed. New York, Churchill Livingstone, 977 p., 1992.. Unique Identifier : AIDSLINE ICDB/94601684; Anonymous; No affiliation given; The diagnosis and treatment of infectious diseases has always been an integral part of pediatric medicine. During recent years its importance has increased logarithmically as a result of new sources of immunosuppression. Accompanying this increase has been a change in the spectrum of potential pathogens. Organisms onc
Friend virus-transformed cells express hemoglobin and become responsive to erythropoietin upon expression of p53 protein (Meeting abstract).: 6th p53 Workshop. November 1-5, 1992, Tiberias, Israel, p. 38, 1992.. Unique Identifier : AIDSLINE ICDB/94698122; Johnson P; Chung S; Benchimol S; Dept. of Medical Biophysics, Ontario Cancer Inst., Univ. of; Toronto, Toronto, Ontario, Canada; The murine allele ts p53val135 encodes a temperature-sensitive p53 protein that behaves as a mutant polypeptide at 37 C and as a wild type polypeptide at 32 C. We have stably introduced this ts allele into the p53 nonproducer, Friend erythroleukemia cell line DP16-1. This cell line was derived from a mouse infected wi
Premalignancy and oral neoplasia in HIV-infected patients (Meeting abstract).: CCPC-93: Second International Cancer Chemo Prevention Conference. April 28-30, 1993, Berlin, Germany, p. 73, 1993.. Unique Identifier : AIDSLINE ICDB/94696755; Langford A; Rudolf Virchow, Augustenburger Platz 1, Berlin, Germany; Generally, HIV-infected patients are at greater risk for developing malignancies. The prime causative factor seems to be their immune-suppressed state. Immuno-dysregulation and a failure of immune surveillance to recognize oncogenic agents and/or malignant cells is a principal assumption in the development of cancer.
Tamoxifen helps postirradiation recovery of lymphocyte subpopulations (Meeting abstract).: CCPC-93: Second International Cancer Chemo Prevention Conference. April 28-30, 1993, Berlin, Germany, p. 102, 1993.. Unique Identifier : AIDSLINE ICDB/94696782; Lukac J; Kordic D; Kusic Z; Nuclear Medicine and Oncology Dept., University Hosp. 'Sestre; milosrdnice,' Zagreb, Croatia; Besides its antiestrogenic activity, tamoxifen (TMX) seems to exert immunomodulatory effects, suppressing lymphocyte responsiveness to mitogens, potentiating natural killer (NK) activity and increasing the number of circulating NK cells as well. We have compared absolute numbers of CD4+ and CD8+ T lymphocytes, B lymph
T-lymphocytes subsets (CD4/CD8 ratio) in breast cancer patients: a preliminary study (Meeting abstract).: CCPC-93: Second International Cancer Chemo Prevention Conference. April 28-30, 1993, Berlin, Germany, p. 111, 1993.. Unique Identifier : AIDSLINE ICDB/94696790; Sevcikova L; Hunakova L; Chorvath B; Turzova M; Boljesikova E; Postgraduate Medical Sch., Cancer Res. Inst., Bratislava,; Czechoslovakia; T-lymphocyte subsets (CD4/CD8 antigen-positive cells) were determined on peripheral blood lymphocytes from 48 patients with breast cancer of different stages by flow immunocytometry with the aid of anti-CD4 and -CD8 monoclonal antibodies. A broad individual variability of the CD4/CD8 ratio among both healthy donors an
Demonstration of reversed IL-7R/IL-2R expression on CD3+ TIL toward IL-2R with increasing proximity to malignant prostatic cells (Meeting abstract).: FASEB J; 7(3):A428 1993. Unique Identifier : AIDSLINE ICDB/94697227; Kramer G; Steiner G; Reinwald C; Schollhammer A; Binder S; Mehrawi M; Boltz G; Marberger M; Dept. of Urology, Univ. of Vienna, Austria; To obtain exact information on the location and activation marker expression of individual lymphocyte subsets in situ and to arrive at inferences about their function, serial sections of 25 untreated cancer tissues were analyzed for intraepithelial (ie), periepithelial (pe) and perivascular (pv) CD3+ TIL/mm2. In gener
Thoracic AIDS-related lymphoma:CT appearance and CD4 counts (Meeting abstract).: Am J Roentgenol; 160(4, Suppl):97 1993. Unique Identifier : AIDSLINE ICDB/94697401; Sider L; Melany M; Chicago, IL; It is now well recognized that AIDS-related lymphoma (ARL) usually presents as extranodal disease different from lymphoma in immune-competent patients (pts). In this series, we will review our experience in an 8-yr period in order to detect the most frequent presentations of thoracic ARL. In addition, further correlat
Control of the interleukin-2 promoter by the HTLV-I transactivator.: Diss Abstr Int [B]; 54(4):1879 1993. Unique Identifier : AIDSLINE ICDB/94698005; Li M; City Univ. of New York, NY; The 40-kD nuclear protein tax encoded by human T cell leukemia virus type I can transcriptionally activate the interleukin-2 ( IL-2 ) enhancer and prevent inhibition of IL-2 gene expression by the immunosuppressant cyclosporin A. We have identified a tax responsive eleme
Analysis of the transcription factor NF-kappaB: induction, function and associating proteins.: Diss Abstr Int [B]; 54(4):1796 1993. Unique Identifier : AIDSLINE ICDB/94698033; Jamieson CA; Brandeis Univ.; My thesis research had two goals. One was to identify physiological signals that induce the transcription factor NF-kappaB in pre-B and T cells. The second was to understand the biological basis of the paradox that NF-kappaB regulated inducible genes, such as IL-2 rece
Adoptive immunotherapy with purified NK or T cells (Meeting abstract).: Biological Response Modifiers, 2nd International Congress. January 29-31. 1993, San Diego, CA, p. 79, 1993.. Unique Identifier : AIDSLINE ICDB/94698353; Herberman RB; Pittsburgh Cancer Inst., Pittsburgh, PA; Adoptive transfer of peripheral blood lymphocytes with lymphokine-activated killer (LAK) activity or of tumor infiltrating lymphocytes, together with high doses of interleukin 2 (IL2), has been shown to have therapeutic efficacy against metastatic tumors in some experimental animal models and in some cancer patients,
Treatment of HIV-1 infection with combination therapy: antiretroviral agents + biologic response modifiers (Meeting abstract).: Biological Response Modifiers, 2nd International Congress. January 29-31. 1993, San Diego, CA, p. 84, 1993.. Unique Identifier : AIDSLINE ICDB/94698356; Schnittman SM; Div. of AIDS, NIAID, NIH, Rockville, MD; HIV-1 infects the CD4+ T lymphocyte population leading to progressive decline in immunologic function, and to development of AIDS. Despite the activity and clinical benefit of antiretroviral therapies, these agents fail to halt the disease progression. Antiretrovirals diminish viral replication but result in modest, s
Effects of experimental feline leukemia virus infection on peripheral lymphocyte subsets.: Diss Abstr Int [B]; 54(5):2394 1993. Unique Identifier : AIDSLINE ICDB/94698747; Nelson PD; North Carolina State Univ. at Raleigh; Feline leukemia virus (FeLV) is a retrovirus of cats that commonly causes immunosuppression and neoplasia of various cellular origins. FeLV-infected cats generally exhibit clinical symptoms of chronic infections, and reduced cell-mediated responses to antigen challenges, similar to humans infected with human immunodef
Epitope selection and design of synthetic vaccines (Meeting abstract).: Specific Immunotherapy of Cancer with Vaccines. January 21-24, 1993, Washington, DC, A30 1993.. Unique Identifier : AIDSLINE ICDB/94698148; Berzofsky JA; NCI, Bethesda, MD 20892; Recent advances in the understanding of antigen processing and presentation facilitate the identification of antigenic sites recognized by CD4+ helper T cells and by CD8+ cytotoxic T lymphocytes (CTL), and suggest methods to optimize the activity of these for construction of synthetic peptide vaccines aimed at eliciti
Efficacy of CHOP and G-CSF combination treatment versus CHOP monotherapy in HIV-1 infected patient with NHL (Meeting abstract).: Biological Response Modifiers, 2nd International Congress. January 29-31. 1993, San Diego, CA, p. 76, 1993.. Unique Identifier : AIDSLINE ICDB/94698348; Gori A; Ridolfo AL; Romaniello A; Franzetti F; Coppin P; Formenti T; Gervasoni C; d'Arminio Monforte A; Moroni M; Clinic of Infectious Diseases, Univ. of Milan, Italy; Objective: To evaluate whether G-CSF and CHOP treatment in HIV-1 infected patients with high-grade NHL allows a better adherence to the therapeutic schedule as compared to patients treated with CHOP alone. Methods: We evaluated retrospectively 6 patients treated with CHOP compared with 8 patients treated with CHOP ass
HIV-associated disease of the nervous system: review of nomenclature and proposal for neuropathology-based terminology.: Brain Pathol. 1991 Apr;1(3):143-52. Unique Identifier : AIDSLINE MED/94122946; Budka H; Wiley CA; Kleihues P; Artigas J; Asbury AK; Cho ES; Cornblath DR; Dal Canto MC; DeGirolami U; Dickson D; et al; Neurological Institute, University of Vienna, Wien, Austria.
AIDS dementia complex and HIV-1 infection: a view from the clinic.: Brain Pathol. 1991 Apr;1(3):155-62. Unique Identifier : AIDSLINE MED/94122947; Price RW; Sidtis JJ; Brew BJ; Department of Neurology, University of Minnesota, Minneapolis; 55455-0323.; The AIDS dementia complex (ADC) is a clinical syndrome which characteristically presents as a subcortical dementia with cognitive, motor and behavioral changes. While the pathogenesis remains puzzling in a number of critical aspects, ADC likely relates in a fundamental way to HIV-1
Neuropathology of human immunodeficiency virus infection.: Brain Pathol. 1991 Apr;1(3):163-75. Unique Identifier : AIDSLINE MED/94122948; Budka H; Neurological Institute, University of Vienna, Wien, Austria.; Neuropathology has defined novel HIV-specific diseases at tissue level: HIV encephalitis and HIV leukoencephalopathy. Both occur usually in the later stages of the AIDS infection and consistently demonstrate large amounts of HIV products. In contrast to this HIV-specific neuropathology, HIV-associated neuropathology f
Immunopathogenesis of HIV encephalitis.: Brain Pathol. 1991 Apr;1(3):177-84. Unique Identifier : AIDSLINE MED/94122949; Achim CL; Schrier RD; Wiley CA; Department of Pathology, University of California San Diego, La; Jolla 92093-0612.; HIV infection leads to severe immunosuppression and in a sub-population of patients, encephalitis. Whether systemic immunosuppression is required for CNS infection is still unclear. However, latent infection of monocytes/macrophages is an important mechanism by which HIV escapes immune surveillance and enters the CNS.
Neurotropism of human immunodeficiency virus.: Brain Pathol. 1991 Apr;1(3):185-91. Unique Identifier : AIDSLINE MED/94122950; Chiodi F; Fenyo EM; Department of Virology, Karolinska Institute, Stockholm, Sweden.; Three major characteristics of human immunodeficiency virus (HIV) infection define HIV as neurotropic. 1) Clinically, distinct neurological syndromes are associated with HIV infection and 2) presence of the virus as well as 3) pathological changes can be demonstrated in the central nervous system. Spread of HIV to the
HIV-related neurotoxicity.: Brain Pathol. 1991 Apr;1(3):193-9. Unique Identifier : AIDSLINE MED/94122951; Lipton SA; Department of Neurology, Children's Hospital, Beth Israel; Hospital, Brigham.; The central nervous system manifestations of AIDS were originally thought to consist solely of white matter lesions, but recent evidence has shown that a substantial degree of neuronal loss can also occur. This review presents evidence for HIV-related toxic factors that may account at least in part for this newly-reco
Neurobiology of simian and feline immunodeficiency virus infections.: Brain Pathol. 1991 Apr;1(3):201-12. Unique Identifier : AIDSLINE MED/94122952; Lackner AA; Dandekar S; Gardner MB; California Regional Primate Research Center, University of; California, Davis 95617-8542.; Experimental and clinical evidence indicates that all lentiviruses of animals and humans are neurotropic and potentially neurovirulent. The prototypic animal lentiviruses, visna virus in sheep and caprine arthritis encephalitis virus in goats have been known for decades to induce neurologic disease. More recently, inf
[Gula Villan as an example (editorial)]: Vardfacket. 1991 Mar 21;15(6):3. Unique Identifier : AIDSLINE MED/94127097; Nyman K
Format of regular tables summarising data on reported AIDS cases and HIV-1 antibody positive persons. PHLS AIDS Centre at the Communicable Disease Surveillance Centre and the Communicable Diseases (Scotland) Unit.: CDR (Lond Engl Rev). 1991 Jan 4;1(1):R6-9. Unique Identifier : AIDSLINE MED/94138418
Tuberculosis in perspective.: CDR (Lond Engl Rev). 1991 Nov 8;1(12):R129-32. Unique Identifier : AIDSLINE MED/94138428; Watson JM
Tuberculosis in developing countries.: CDR (Lond Engl Rev). 1991 Nov 8;1(12):R136-9. Unique Identifier : AIDSLINE MED/94138431; Porter JD; Department of Clinical Sciences, London School of Hygiene and; Tropical Medicine.; Every year, between six and eight million people worldwide develop tuberculosis and 2-3 million die of the disease. The situation is worsening due to the epidemic of human immunodeficiency virus (HIV) infection and reactivation of tuberculosis in patients with dual infection . The World Health Organisation estimated
Screening of blood donations for HIV-1 antibody: 1985-1991.: CDR (Lond Engl Rev). 1991 Dec 6;1(13):R144-6. Unique Identifier : AIDSLINE MED/94138434; Gunson HH; Rawlinson VI; North Western Regional Transfusion Centre, Manchester.; One hundred and ninety HIV-1 antibody positive donors have been detected, out of 14.85 million blood donations screened in the United Kingdom and the Isle of Man , since the start of testing in Octobe
Voluntary antenatal HIV testing--results of a pilot study.: CDR (Lond Engl Rev). 1991 Dec 6;1(13):R147-8. Unique Identifier : AIDSLINE MED/94138435; Miller E; Miller CL; Killick SR; Craske J; Waight PA; Voluntary testing for antibody to human immunodeficiency virus (HIV) was offered to 4929 antenatal patients attending two hospitals in South Manchester during a 12 month period in 1989/90 in order to assess the feasibility of obtaining seroprevalence data by this method. Of these patients, 1728 (35%) agreed to a named
The diagnosis of fungal infections.: CDR (Lond Engl Rev). 1991 Dec 6;1(13):R150-1. Unique Identifier : AIDSLINE MED/94138437; Mackenzie DW
Notifications of tuberculosis in England and Wales, 1982-1989.: CDR (Lond Engl Rev). 1991 Feb 1;1(2):R13-6. Unique Identifier : AIDSLINE MED/94138438; Watson JM; Fern KJ; Porter JD; Whitmore SE
HIV-2 in the United Kingdom--a review.: CDR (Lond Engl Rev). 1991 Feb 1;1(2):R19-23. Unique Identifier : AIDSLINE MED/94138440; Evans BG; Gill ON; Gleave SR; Mortimer PP; Parry JV; Human immunodeficiency virus type 2 (HIV-2) was first recognised in 1986 and subsequently the infection was shown to be widespread in West Africa. There have been few case reports from countries outside the African continent. In North America and Europe the highest number of infections have been in
Travel, heterosexual intercourse and HIV-1 infection.: CDR (Lond Engl Rev). 1991 Mar 29;1(4):R39-43. Unique Identifier : AIDSLINE MED/94138446; Noone A; Gill ON; Clarke SE; Porter K; One hundred and seventy AIDS cases and 547 HIV-1 antibody positive reports of infection in persons who are presumed to have become infected by sexual intercourse between men and women abroad are reviewed. Eighty three percent of people with AIDS and 99% of HIV-1 infected persons were reported to have been exposed in c
The surveillance of HIV-1 infection and AIDS in England and Wales. PHLS AIDS Centre.: CDR (Lond Engl Rev). 1991 Apr 26;1(5):R51-6. Unique Identifier : AIDSLINE MED/94138449; Comprehensive surveillance is necessary for effective and efficient primary prevention as well as appropriate resource allocation for patient care. The surveillance of HIV-1 infections and AIDS in England and Wales is based upon voluntary confidential reporting by clinicians of AIDS cases and deaths in HIV-1 infected
The unlinked anonymous HIV prevalence monitoring programme in England and Wales: preliminary results.: CDR (Lond Engl Rev). 1991 Jun 21;1(7):R69-76. Unique Identifier : AIDSLINE MED/94138456; Results are presented from unlinked anonymous HIV-1 testing of specimens collected during 1990 from 8996 genito-urinary medicine clinic attenders, 1421 injecting drug users, and 69,091 pregnant women. One-fifth of homo/bisexual men attending London genito-urinary medicine clinics were infected with HIV-1. The figure w
Acquired immune deficiency syndrome: United Kingdom 1982-November 1990.: CDR (Lond Engl Wkly). 1991 Jan 4;1(1):3-6. Unique Identifier : AIDSLINE MED/94138471
AIDS and HIV-1 antibody reports--United Kingdom.: CDR (Lond Engl Wkly). 1991 Mar 8;1(10):45-6. Unique Identifier : AIDSLINE MED/94138473
Cavitating pneumonia caused by Rhodococcus equi in a patient with AIDS.: CDR (Lond Engl Wkly). 1991 Mar 8;1(10):48. Unique Identifier : AIDSLINE MED/94138474; Eykyn SJ; Department of Microbiology, St Thomas's Hospital, London.
Prophylaxis against Pneumocystis carinii pneumonia in children infected with human immunodeficiency virus.: CDR (Lond Engl Wkly). 1991 Apr 12;1(15):65. Unique Identifier : AIDSLINE MED/94138478
AIDS and HIV-1 antibody reports--United Kingdom.: CDR (Lond Engl Wkly). 1991 Apr 12;1(15):67-8. Unique Identifier : AIDSLINE MED/94138479
AIDS and HIV-1 antibody reports--United Kingdom.: CDR (Lond Engl Wkly). 1991 May 10;1(19):85-6. Unique Identifier : AIDSLINE MED/94138484
Preliminary results of the unlinked anonymous HIV prevalence monitoring programme in England and Wales.: CDR (Lond Engl Wkly). 1991 May 24;1(21):93. Unique Identifier : AIDSLINE MED/94138487
HIV infection in travellers.: CDR (Lond Engl Wkly). 1991 May 31;1(22):97. Unique Identifier : AIDSLINE MED/94138488
AIDS and HIV-1 antibody reports--United Kingdom.: CDR (Lond Engl Wkly). 1991 Jun 7;1(23):103-4. Unique Identifier : AIDSLINE MED/94138494
AIDS and HIV-1 antibody reports--United Kingdom.: CDR (Lond Engl Wkly). 1991 Jan 18;1(3):13-4. Unique Identifier : AIDSLINE MED/94138496
Reporting of HIV-2 infections in the United Kingdom.: CDR (Lond Engl Wkly). 1991 Feb 1;1(5):21. Unique Identifier : AIDSLINE MED/94138498
Transmission of HIV-1 infection during an invasive dental procedure--United States.: CDR (Lond Engl Wkly). 1991 Feb 1;1(5):21. Unique Identifier : AIDSLINE MED/94138499
AIDS and HIV-1 antibody reports--United Kingdom.: CDR (Lond Engl Wkly). 1991 Feb 8;1(6):27-9. Unique Identifier : AIDSLINE MED/94138501
Neurological and neuropsychological complications of HIV infection, Monterey, California, June 16-19, 1990.: Brain Pathol. 1990 Sep;1(1):63-4. Unique Identifier : AIDSLINE MED/94122936; Wiley CA; Department of Pathology, University of California, San Diego.; In summary this important conference covered the entire gamut of issues regarding retroviral damage of the central nervous system. Neuropathologists interested in this rapidly moving field should strongly consider attending the next satellite conference to be held in June 1991 in Florence,
Spectral effects in activation of the human immunodeficiency virus promoter by psoralens plus ultraviolet A treatment.: Photodermatol Photoimmunol Photomed. 1992-93 Dec;9(6):262-7. Unique Identifier : AIDSLINE MED/94128579; Miller SA; Beer JZ; Strickland AG; Zmudzka BZ; Center for Devices and Radiological Health, US Food and Drug; Administration, Rockville, MD 20857.; The effects of PUVA treatment on HIV promoter activation and cell killing in HIV cat/HeLa cells were studied using two UV sources, a UVASUN sunlamp and a UVAR Photoactivation Chamber. A 4 to 5 times higher dose of ultraviolet radiation was required from the UVASUN lamp than from the UVAR lamps: 1) to activate the HIV
AIDS-related knowledge, attitudes, and behaviors among juvenile delinquents in Israel.: Public Health Rev. 1992-93;20(3-4):241-50. Unique Identifier : AIDSLINE MED/94134953; Slonim-Nevo V; Department of Social Work, Ben-Gurion University of the Negev,; Beer Sheva, Israel.; Fifty-six Israeli adolescents under the care of probation officers were interviewed about their AIDS-related knowledge, attitudes, and behaviors. The results suggest that these adolescents put themselves at risk of HIV infection. A substantial proportion of the sample demonstrated a lack of knowledge on issues relevan
Disseminated American muco-cutaneous leishmaniasis caused by Leishmania braziliensis braziliensis in a patient with AIDS: a case report.: Mem Inst Oswaldo Cruz. 1992 Oct-Dec;87(4):487-92. Unique Identifier : AIDSLINE MED/94142536; Machado ES; Braga M da P; Da Cruz AM; Coutinho SG; Vieira AR; Rutowitsch MS; Cuzzi-Maya T; Grimaldi junior G; Menezes JA; Servico de DIP, Hospital dos Servidores do Estado, Rio de; Janeiro, Brasil.; The authors report a case of culture-proven disseminated American muco-cutaneous leishmaniasis caused by Leishmania braziliensis braziliensis in an HIV positive patient. Lesions began in the oropharynx and nasal mucosa eventually spreading to much of the skin surface. The response to a short course of glucantime thera
Progression of HIV-infection: markers or determinants.: Trans Am Clin Climatol Assoc. 1992;104:123-8; discussion 128-9. Unique Identifier : AIDSLINE MED/94135855; Phair JP; Farzadegan H; Chmiel J; Munoz A; Detels R; Saah A; Kaslow R; Department of Medicine, Northwestern University Medical School,; Chicago, Illinois.
Development of inhibitors of reverse transcriptase and protease as therapeutics against HIV infection.: J Enzyme Inhib. 1992;6(1):1-8. Unique Identifier : AIDSLINE MED/94132920; Mitsuya H; Experimental Retrovirology Section, National Cancer Institute,; Bethesda, Maryland.
Inhibitors of HIV-1 reverse transcriptase and fidelity of in vitro DNA replication.: J Enzyme Inhib. 1992;6(1):35-46. Unique Identifier : AIDSLINE MED/94132921; Abbotts J; Wilson SH; Laboratory of Biochemistry, National Cancer Institute, National; Institutes of Health, Bethesda, Maryland 20892.; Mechanisms of the effects of the dTTP analogues 3 -azido-3 -deoxythymidine 5 -triphosphate (AZTTP) and 3 -amino-3 -deoxythymidine 5 -triphosphate (NH2 TTP) upon the HIV-1 reverse transcriptase (RT) are discussed. These compounds block the RT in vitro and do so by different kinetic mechanisms. Infidelity of replication
Specific HIV-1 reverse transcriptase inhibitors.: J Enzyme Inhib. 1992;6(1):47-53. Unique Identifier : AIDSLINE MED/94132922; Debyser Z; Pauwels R; Andries K; De Clercq E; Rega Institute for Medical Research, Katholieke Universiteit; Leuven, Belgium.
Emergence of mutant HIV reverse transcriptase conferring resistance to AZT.: J Enzyme Inhib. 1992;6(1):55-64. Unique Identifier : AIDSLINE MED/94132923; Richman DD; Department of Pathology, University of California San Diego.
Inhibitors of HIV-1 protease.: J Enzyme Inhib. 1992;6(1):65-98. Unique Identifier : AIDSLINE MED/94132924; Meek TD; Department of Medicinal Chemistry, SmithKline Beecham; Pharmaceuticals, King of Prussia, Pennsylvania 19406.; The human immunodeficiency virus (HIV), the etiological agent for the acquired immune deficiency syndrome (AIDS), is a retrovirus which makes use of a virally-encoded aspartic protease to perform specific proteolytic processing of two of its gene products in order to form active enzymes and structural proteins within
Correlations between the in vitro and in vivo activity of anti-HIV agents: implications for future drug development.: J Enzyme Inhib. 1992;6(1):99-111. Unique Identifier : AIDSLINE MED/94132926; Yarchoan R; Broder S; Medicine Branch, National Cancer Institute, NIH, Bethesda, MD; 20892.; Some 10 years after the first recognition of acquired immunodeficiency syndrome (AIDS) as a new syndrome, we have identified a number of molecular targets to interrupt the replicative cycle of human immunodeficiency virus (HIV), the causative agent. A number of dideoxynucleosides have been identified as having anti-HI
HIV seropositivity among female prostitutes and nonprostitutes: obstetric and perinatal implications.: Viral Immunol. 1993 Fall;6(3):171-4. Unique Identifier : AIDSLINE MED/94121745; Obi CL; Ogbonna BA; Igumbor EO; Ndip RN; Ajayi AO; Faculty of Science, Department of Biological Sciences; (Microbiology Unit), University of Lagos, Akoka, Nigeria.; Serum samples totaling 600 were obtained from female prostitutes (300) resident in different hotels in Lagos, Nigeria and nonprostitutes (300) attending different health centers for routine check-up in Lagos, Nigeria. Sera obtained were screened for the prevalence of HIV seroposit
HIV-1 in human alveolar macrophages from infected patients is latent in vivo but replicates after in vitro stimulation.: Am J Respir Cell Mol Biol. 1994 Jan;10(1):72-8. Unique Identifier : AIDSLINE MED/94121942; Lebargy F; Branellec A; Deforges L; Bignon J; Bernaudin JF; INSERM U 139, Hopital Henri Mondor, Creteil, France.; It has been demonstrated that alveolar macrophages (AM) are permissive for human immunodeficiency virus (HIV-1) after in vitro infection. However, data concerning in vivo infection of AM by HIV-1 still conflict. Therefore, we investigated AM collected by bronchoalveolar lavage from 15 HIV-1-infected patients. HIV-1 p2
Pharmacokinetics of an HIV-1 gp120-specific chimeric antibody in patients with HIV-1 disease.: Biotherapy. 1993;6(3):205-15. Unique Identifier : AIDSLINE MED/94122031; Schupbach J; Gunthard H; Fung MS; Liou RS; Botta L; Gowland P; Gordon W; Gygax D; Chang NT; Chang TW; et al; Swiss National Center for Retroviruses, University of Zurich.; The pharmacokinetics of mouse V/human C (gamma 1, kappa) chimeric monoclonal antibody CGP 47 439 specific for the principal neutralizing determinant of human immunodeficiency virus type 1 (HIV-1) was studied in patients with stage IV HIV-1 disease in an open-labeled phase I/IIA trial. Twelve male patients were enrolle
HIV and opportunistic infections: which makes the heart vulnerable? [editorial]: Br J Clin Pract. 1993 Sep-Oct;47(5):232-3. Unique Identifier : AIDSLINE MED/94122035; Akhras F
Noncytotoxic approaches to the treatment of HIV-associated Kaposi's sarcoma.: Oncology (Huntingt). 1993 Dec;7(12):25-33; discussion 33, 37-8. Unique Identifier : AIDSLINE MED/94122077; Pluda JM; Parkinson DR; Feigal E; Yarchoan R; Investigational Drug Branch, CTEP/DCT/NCI, Rockville, MD 20852.; Kaposi s sarcoma (KS) is an otherwise unusual disease that frequently complicates the course of HIV infection. While there is some evidence to suggest that the pathogenesis of KS is driven by a variety of cytokines and cellular factors, the exact pathogenesis of the disease is unknown at present. Current therapy for H
Tuberculosis preventive therapy in HIV-infected individuals. A Joint Statement of the WHO Tuberculosis Programme and the Global Programme on AIDS, and the International Union Against Tuberculosis and Lung Disease (IUATLD).: Wkly Epidemiol Rec. 1993 Dec 3;68(49):361-4. Unique Identifier : AIDSLINE MED/94122103
Demographic, medical history and sexual correlates of HIV seropositive methadone maintained women.: J Addict Dis. 1993;12(4):105-20. Unique Identifier : AIDSLINE MED/94122218; Ajuluchukwu DC; Brown LS Jr; Crummey FC; Foster KF Sr; Ismail YI; Siddiqui N; Evaluation & Research, Division of Medical Services, Evaluation &; Research, Addiction Research & Treatment Corporation, Brooklyn,; NY 11201.; Beginning in January 1989, consecutive female admissions to the ARTC MMTP Clinics in NYC were interviewed about their medical, drug, sexual and social experiences during 6 distinct historical years. Bloods were drawn and each sample tested for HIV via ELISA and Western Blot analysis. The data for 256 females was analy
Medical disorders in a cohort of New York city drug abusers: much more than HIV disease.: J Addict Dis. 1993;12(4):11-27. Unique Identifier : AIDSLINE MED/94122219; Brown LS Jr; Hickson MJ; Ajuluchukwu DC; Bailey J; Division of Medical Services, Evaluation and Research, Addiction; Research and Treatment Corporation, Brooklyn, NY.; We evaluated the medical histories, drug abuse patterns, sexual behaviors, serological studies for syphilis and hepatitis B infection and other laboratory studies in 1780 patients enrolled in New York City drug treatment clinics in 1987. HIV serology was available for 168 patients. Nearly seventy-five percent had at l
Drug abuse treatment programs as centers for HIV-related research and treatment.: J Addict Dis. 1993;12(4):121-9. Unique Identifier : AIDSLINE MED/94122220; Sawyer RC; Brown LS Jr; Bailey J; Hickson M; Lee P; McNair D; Rawls J; Skinner A; Division of Medical Service, Addiction Research and Treatment; Corporation, Brooklyn, NY 11201.; The Observational Data Base (ODB) is a multicenter, longitudinal effort of the Community Programs for Clinical Research in AIDS (CPCRA) designed to collect HIV-related data on a large number of HIV-infected patients receiving primary care from community based physicians and health care groups. Over 400 patients from t
Diminished illicit drug use as a consequence of long-term methadone maintenance.: J Addict Dis. 1993;12(4):45-57. Unique Identifier : AIDSLINE MED/94122224; Gottheil E; Sterling RC; Weinstein SP; Department of Psychiatry and Human Behavior, Jefferson Medical; College, Philadelphia, PA 19107.; In the twenty-five years since its introduction as a treatment for opiate addiction, methadone maintenance has generated considerable controversy regarding both its appropriateness as a treatment modality and its efficacy in diminishing opiate abuse. Given current concerns regarding the spread of HIV amongst IV drug a
Medical maintenance: a pilot study.: J Addict Dis. 1993;12(4):59-76. Unique Identifier : AIDSLINE MED/94122225; Senay EC; Barthwell AG; Marks R; Bokos P; Gillman D; White R; Illinois Department of Alcoholism and Substance, University of; Chicago.; In a one year study, 130 methadone maintained subjects with a six month history of good treatment performance were assigned randomly to an experimental condition of one monthly non-random urine screen, one monthly counseling session, one monthly doctor visit, two times per month methadone pick up, a quarterly true ran
Intrathecal synthesis of beta 2-microglobulin and lysozyme: differential markers of nervous system involvement in patients infected with human immunodeficiency virus type 1.: Eur J Clin Chem Clin Biochem. 1993 Oct;31(10):609-15. Unique Identifier : AIDSLINE MED/94122248; Meillet D; Belec L; Celton N; Gervais A; Reboul J; Gentilini M; Delattre J; Schuller E; Laboratoire de Biochimie, Hopital de la Salpetriere, Paris,; France.; beta 2-Microglobulin and lysozyme were determined in paired serum and cerebrospinal fluid samples from 137 patients, using immunofluorometry and ELISA, respectively. Of these patients, 54 were infected by human immunodeficiency virus type 1 (HIV1) (including 20 AIDS dementia patien
HIV and complement: role of the complement system in HIV infection.: Int Arch Allergy Immunol. 1994;103(2):113-7. Unique Identifier : AIDSLINE MED/94122535; Marschang P; Ebenbichler CF; Dierich MP; Institut fur Hygiene, Innsbruck, Austria.; HIV, in contrast to animal retroviruses, is not lysed by human serum but nevertheless the virus as well as virus-infected cells activate the complement system efficiently. HIV activates the classical pathway by binding C1q to the transmembrane protein gp41. On the surface of HIV-infected cells, both the alternative an
Infectious AIDS--stretching the germ theory beyond its limits.: Int Arch Allergy Immunol. 1994;103(2):118-27. Unique Identifier : AIDSLINE MED/94122536; Duesberg P; Department of Molecular and Cell Biology, University of; California, Berkeley 94720.; The hypothesis that human immunodeficiency virus (HIV) causes AIDS was advanced in 1984, based only on circumstantial evidence. To this date, the primary evidence are correlations between the presence of antibody against HIV and AIDS. But these correlations are biased by proponents of the HIV hypothesis in favour of H
Duesberg on AIDS--stretching our benevolence beyond its limits.: Int Arch Allergy Immunol. 1994;103(2):128-30. Unique Identifier : AIDSLINE MED/94122537; Lindenmann J; University of Zurich, Switzerland.
[Alternative strategy for the diagnosis of HIV infection in sub-saharan Africa. Value of the sequential combination of the ELISA test and a 2nd generation rapid test]: Bull Soc Pathol Exot. 1993;86(4):236-42. Unique Identifier : AIDSLINE MED/94122551; Gresenguet G; Tevi-Benissan C; Payan C; Pascal B; Matta M; Dragon MA; Belec L; Service de Microbiologie (Virologie), Hopital Broussais, Paris,; France.; The conventional algorithm for HIV testing based on the confirmation of all positive anti-HIV screening reactions by Western blot requires sufficient laboratory facilities and is expensive, that limits its use in developing countries, such as in subsaharian Africa. The apparition of second and third generation screeni
AIDS: global lessons from a global epidemic [editorial]: BMJ. 1993 Dec 18-25;307(6919):1574-5. Unique Identifier : AIDSLINE MED/94122631; Mann J; Wilson ME
HIV experimental vaccines based on the iscom technology using envelope and GAG gene products.: Biotechnol Ther. 1993;4(3-4):145-61. Unique Identifier : AIDSLINE MED/94122664; Akerblom L; Nara P; Dunlop N; Putney S; Morein B; National Veterinary Institute, Department of Virology, Uppsala,; Sweden.; In previous experiments gp160 incorporated into iscom was shown to induce neutralizing antibodies to the homologous as well as the heterologous isolates of HIV-1 (Akerblom et al., AIDS Res., 1991). In the present work we have incorporated into iscoms three defined recombinant DNA products of HIV-1. The carboxy-termina
Inhibition of the spore polar filament extrusion of the microsporidium, Encephalitozoon hellem, isolated from an AIDS patient.: J Eukaryot Microbiol. 1993 Nov-Dec;40(6):711-7. Unique Identifier : AIDSLINE MED/94122699; Leitch GJ; He Q; Wallace S; Visvesvara GS; Department of Physiology, Morehouse School of Medicine, Atlanta,; Georgia 30310-1495.; Spores of the microsporidian parasitic protozoan Encephalitozoon hellem were purified and incubated at 37 degrees C in a solution with an electrolyte composition similar to that of mammalian extracellular fluid, and in solution in which the calcium had been replaced with 0.2 mM EGTA. Polar filament extrusion (germinat
Genes encoding antigenic surface glycoproteins in Pneumocystis from humans.: J Eukaryot Microbiol. 1993 Nov-Dec;40(6):821-6. Unique Identifier : AIDSLINE MED/94122711; Stringer SL; Garbe T; Sunkin SM; Stringer JR; Department of Molecular Genetics, Biochemistry, and Microbiology,; University of Cincinnati, College of Medicine, Ohio 45267.; Pneumocystis is a eukaryotic microbe that causes pneumocystosis, an AIDS-associated pneumonia. Pneumocystosis also occurs in many other mammalian species, and animal-derived organisms have been extensively utilized in Pneumocystis research. Pneumocystis from diverse hosts contain a large glycoprotein (gpA/MSG) on the
[Association of rheumatoid arthritis and Kaposi disease. Apropos of a case arising after intraarticular corticotherapy]: Rev Rhum Ed Fr. 1993 Mar;60(3):240-4. Unique Identifier : AIDSLINE MED/94122721; Azais I; Lambert de Cursay G; Deblais F; Deschamps O; Gandon P; Alcalay M; Bontoux D; Service de Rhumatologie, CHRU Poitiers.; A 66 year old Corsican HLA A2 and DR5-positive male with moderately active seropositive destructive rheumatoid arthritis developed Kaposi s sarcoma after intraarticular administration of corticosteroids. He had no history of oral corticosteroid therapy, organ transplantation, AIDS, or cancer. Chlorambucil proved ineff
Toxic neuropathies and myopathies.: Curr Opin Neurol. 1993 Oct;6(5):695-704. Unique Identifier : AIDSLINE MED/94122889; Kuncl RW; George EB; Department of Neurology, Johns Hopkins University School of; Medicine, Baltimore, MD 21287-7519.; This review first considers toxic neuropathies of recent interest, including those caused by antineoplastic and antiretroviral drugs, agents that affect methylation reactions, vitamin and herbal preparations, and certain occupational exposures. The discussion points out the interesting phenomenon of coasting, the stra
Magnetic resonance imaging in demyelinating, infectious, metabolic, and congenital diseases.: Curr Opin Neurol. 1993 Dec;6(6):912-8. Unique Identifier : AIDSLINE MED/94122918; Mechtler LL; Kinkel PR; Division of Neuroimaging Research, Millard Fillmore Hospitals,; Lucy Dent Imaging Center, Buffalo, NY 14209.; A mere 5 to 7 years ago, the majority of literature on demyelinating, infectious, metabolic, and congenital diseases of the brain focused on comparison between computed tomography and magnetic resonance imaging (MRI). MRI has become not only the foremost diagnostic tool in imaging of the central nervous system, but al
The pathogenesis of murine retroviral infection of the central nervous system.: Brain Pathol. 1993 Apr;3(2):123-8. Unique Identifier : AIDSLINE MED/94122969; Wiley CA; Gardner M; Department of Pathology, University of California, San Diego, La; Jolla 92093-0612.; Several decades have lapsed since the original description of retroviral infection of the central nervous system (CNS) appeared. With the recent arrival of the autoimmune deficiency syndrome (AIDS) epidemic and the associated human retroviral encephalitis, interest in murine models has been rekindled. In most of the p
[Pregnancy and AIDS--the present situation in the Czech Republic]: Cesk Gynekol. 1993 Dec;58(6):302-6. Unique Identifier : AIDSLINE MED/94123386; Roztocil A; Stankova M; Pilka L; II. gynek.-porod. klinika MU, Brno.
Cardiac mitochondrial DNA polymerase-gamma is inhibited competitively and noncompetitively by phosphorylated zidovudine.: Circ Res. 1994 Feb;74(2):344-8. Unique Identifier : AIDSLINE MED/94123453; Lewis W; Simpson JF; Meyer RR; Department of Pathology and Laboratory Medicine, University of; Cincinnati, College of Medicine, OH.; Zidovudine (azidothymidine [ AZT ]) inhibits human immunodeficiency virus replication and reduces the severity of acquired immunodeficiency syndrome. A limiting side effect of AZT is a mitochondrial cardiac and skeletal myopathy in which the pharmacolog
Human immunodeficiency virus and the obstetrician.: Clin Obstet Gynecol. 1993 Dec;36(4):821-31. Unique Identifier : AIDSLINE MED/94123467; Lindsay MK; Grady Memorial Hospital, Department of Gynecology and Obstetrics,; Emory University School of Medicine, Atlanta, GA 30335.
Safety issues, risks, and precautions for dermatologic surgery.: Cutis. 1993 Dec;52(6):345-7. Unique Identifier : AIDSLINE MED/94123588; Robinson JK; Northwestern University Medical School, Chicago, Illinois 60611.; The use of universal precautions can provide an effective barrier to transmission of viral infections. The most common route of occupational human immunodeficiency virus transmission to a health care provider is a self-inflicted needle stick with a contaminated needle. Use of the no-touch suturing technique in dermato
HIV infection among secondary school students in Djibouti, horn of Africa: knowledge, exposure and prevalence.: East Afr Med J. 1993 Jul;70(7):414-7. Unique Identifier : AIDSLINE MED/94123617; Rodier GR; Morand JJ; Olson JS; Watts DM; Said-Salah; Epidemiology Branch, US Naval Medical Research Unit 3 (NAMRU-3),; FPO AE 09835-0007.; A study of HIV infection among secondary school students was conducted in Djibouti in February 1990 during a national hepatitis survey. Serology was negative for HIV and syphilis among 294 students (ages 14 to 20 years) in spite of a dramatic increase of HIV seropositivity (as hi
Safer sex knowledge, behavior, and attitudes of inner-city women.: Health Psychol. 1993 Nov;12(6):481-8. Unique Identifier : AIDSLINE MED/94123665; Hobfoll SE; Jackson AP; Lavin J; Britton PJ; Shepherd JB; Applied Psychology Center, Kent State University, Ohio 44242.; Sexual behavior, knowledge of HIV transmission and prevention, perceived risk of AIDS, and safer sex behavior were studied in a sample of 289 single, pregnant, inner-city women. African-American and European-American women were equally represented. Women had poor AIDS knowledge. Sexual behavior placed women at risk fo
Self-perception variables that mediate AIDS-preventive behavior in college students.: Health Psychol. 1993 Nov;12(6):489-98. Unique Identifier : AIDSLINE MED/94123666; Goldman JA; Harlow LL; Three psychological variables--self-efficacy, control and meaning, and perceived risk--were tested in a structural model predicting AIDS-preventive behavior. Results revealed a good model fit, indicating that these psychological variables did play a role in mediating AIDS-preventive behavior in college students. A mul
HIV discovery: the final decision? [news]: Experientia. 1994 Jan 15;50(1):I-II. Unique Identifier : AIDSLINE MED/94123745
The intracellular production and secretion of HIV-1 envelope protein in the methylotrophic yeast Pichia pastoris.: Gene. 1993 Dec 22;136(1-2):111-9. Unique Identifier : AIDSLINE MED/94123987; Scorer CA; Buckholz RG; Clare JJ; Romanos MA; Wellcome Research Laboratories, Beckenham, Kent, UK.; The human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein, gp120 (ENV), is required in large quantities for immunological studies and as a potential vaccine component. We have expressed the DNA encoding gp120 in a highly efficient expression system based on the methylotrophic yeast, Pichia pastoris. The na
[Federal public health service--quo vadis?]: Fortschr Med. 1993 Nov 20;111(32):28-30. Unique Identifier : AIDSLINE MED/94124078; Lemmel EM
[The AIDS-blood scandal: Seehover plays with hidden cards. Is a public health administrator permitted to purposely incite hysteria?]: Fortschr Med. 1993 Nov 20;111(32):32. Unique Identifier : AIDSLINE MED/94124079
Serum-soluble CD4 as clinical and immunological marker in patients with dilated cardiomyopathy.: Immunol Lett. 1993 Oct;38(2):103-9. Unique Identifier : AIDSLINE MED/94124173; Klappacher G; Mehrabi M; Plesch K; Mundigler G; Pec M; Kramer G; Pacher R; Ullrich R; Kukutschki W; Imhof M; et al; Department of Clinical Pharmacology, University of Vienna,; Austria.; Serological markers of cell-mediated immunity, i.e., soluble CD4, soluble interleukin-2 (Il-2) receptor and beta 2-microglobulin, were determined in 60 patients with dilated cardiomyopathy. Compared with normal healthy donors (n = 30) and controls who had coronary artery disease with preserved left ventricular functio
Who: promising progress on HIV vaccine [news]: Int Nurs Rev. 1993 Nov-Dec;40(6):103. Unique Identifier : AIDSLINE MED/94124218
Nurses and others settle with AIDS drug maker [news]: Int Nurs Rev. 1993 Nov-Dec;40(6):162. Unique Identifier : AIDSLINE MED/94124219
13 million HIV positive women by 2000 [news]: Int Nurs Rev. 1993 Nov-Dec;40(6):162. Unique Identifier : AIDSLINE MED/94124220
Human immunodeficiency virus type 1 tat gene enhances human papillomavirus early gene expression.: Intervirology. 1993;36(2):57-64. Unique Identifier : AIDSLINE MED/94124226; Tornesello ML; Buonaguro FM; Beth-Giraldo E; Giraldo G; Istituto Nazionale Tumori Fondazione Pascale, Napoli, Italia.; To investigate the possible direct/indirect role of Human immunodeficiency virus (HIV) as a cofactor in human papillomavirus (HPV) oncogenesis, cotransfection experiments were carried out in which a recombinant plasmid containing the HPV16 long control region (LCR) linked to the chloramphenicol acetyltransferase (CAT)
Activation of the human immunodeficiency virus type 1 long terminal repeat by skin-sensitizing chemicals in transgenic mice.: Intervirology. 1993;36(2):65-71. Unique Identifier : AIDSLINE MED/94124227; Morrey JD; Jackson MK; Bunch TD; Sidwell RW; Department of Animal, Dairy and Veterinary Sciences, Utah State; University, Logan 84322-5600.; Topical dinitrochlorobenzene (DNCB) is often used for evaluating contact skin hypersensitivity in immunocompromised patients. We have determined, in this study, that topical application of DNCB alone, even without induction of contact skin hypersensitivity, was sufficient to observe activation of the human immunodefic
Two new candidate adenovirus serotypes.: Intervirology. 1993;36(2):79-83. Unique Identifier : AIDSLINE MED/94124229; Schnurr D; Dondero ME; Viral and Rickettsial Disease Laboratory, California State; Department of Health Services, Berkeley 94704.; Two new adenovirus (AV) subgenus D serotypes, which we propose as AV candidates 48 and 49, are described. Both AV 48 and 49 were unique by serum neutralization and the pattern of restriction endonuclease fragments. By the hemagglutination inhibition assay there was a significant reciprocal cross between AV 48 and 44 a
Identification of human T cell leukemia virus type IIb infection in the Wayu, an aboriginal population of Colombia [published erratum appears in Jpn J Cancer Res 1994 Apr;85(4):441]: Jpn J Cancer Res. 1993 Dec;84(12):1215-8. Unique Identifier : AIDSLINE MED/94124264; Ijichi S; Tajima K; Zaninovic V; Leon FE; Katahira Y; Sonoda S; Miura T; Hayami M; Hall WW; Division of Infectious Diseases, North Shore University Hospital,; Cornell University Medical College, Manhasset, New York 11030.; Human T cell leukemia virus type II (HTLV-II) is endemic in a number of native American populations and high rates of infection have also been demonstrated in intravenous drug abusers (IVDAs). Studies of virus isolates in the latter population have shown the existence of two closely related subtypes of the virus, HTLV
Transmission routes of HTLV-I: an analysis of 66 families.: Jpn J Cancer Res. 1993 Dec;84(12):1265-7. Unique Identifier : AIDSLINE MED/94124272; Take H; Umemoto M; Kusuhara K; Kuraya K; Department of Pediatrics, Kagoshima City Hospital.; HTLV-I transmission routes were found for 66 carrier pregnant women by studying sera, from the carrier pregnant women, their mothers, and their husbands, and by obtaining detailed family histories at interview. Forty-one cases (62.1%) were considered to be instances of vertical transmission, 15 (22.8%) of sexual trans
Isochromophilones I and II, novel inhibitors against gp120-CD4 binding from Penicillium sp. [letter]: J Antibiot (Tokyo). 1993 Dec;46(12):1908-11. Unique Identifier : AIDSLINE MED/94124311; Omura S; Tanaka H; Matsuzaki K; Ikeda H; Masuma R
Current management of hemophilia B.: Hematol Oncol Clin North Am. 1993 Dec;7(6):1269-80. Unique Identifier : AIDSLINE MED/94124391; Roberts HR; Eberst ME; Department of Medicine, University of North Carolina at Chapel; Hill.; The management of hemorrhagic episodes in patients with hemophilia B is in transition as a result of the availability of new products for replacement therapy. Although the basic principles of therapy have not changed, the new highly purified Factor IX concentrates, AlphaNine and Mononine, represent a break-through, as
High activity and stability of hammerhead ribozymes containing 2'-modified pyrimidine nucleosides and phosphorothioates.: J Biol Chem. 1994 Jan 21;269(3):2131-8. Unique Identifier : AIDSLINE MED/94124569; Heidenreich O; Benseler F; Fahrenholz A; Eckstein F; Max-Planck-Institut fur Experimentelle Medizin, Gottingen,; Federal Republic of Germany.; The influence of chemical modifications on the catalytic activity and stability of a hammerhead ribozyme directed against the long terminal repeat RNA of the human immunodeficiency virus 1 was examined. Previous studies had shown that substitution of all pyrimidine nucleosides by their 2 -fluoro analogs led to an 8-fo
HIV-1 transactivator protein Tat induces proliferation and TGF beta expression in human articular chondrocytes.: J Cell Biol. 1994 Feb;124(3):365-71. Unique Identifier : AIDSLINE MED/94124631; Lotz M; Clark-Lewis I; Ganu V; Sam and Rose Stein Institute for Research on Aging, University of; California, San Diego 92093.; The human immunodeficiency virus-1 (HIV-1) protein Tat binds to cell surface antigens and can regulate cellular responses. Tat has similar immunosuppressive effects as transforming growth factor-beta (TGF beta) and both inhibit lymphocyte proliferation. TGF beta is expressed by primary human articular chondrocytes and
Pseudo oral hairy leukoplakia in a renal allograft recipient.: J Am Acad Dermatol. 1994 Feb;30(2 Pt 2):300-3. Unique Identifier : AIDSLINE MED/94124716; Euvrard S; Kanitakis J; Pouteil-Noble C; Chardonnet Y; Touraine JL; Thivolet J; Department of Dermatology, Hopital Edouard Herriot, Lyon,; France.; Oral hairy leukoplakia (OHL) is a disorder of the tongue associated with Epstein-Barr virus (EBV). OHL is seen mainly in HIV infection but is also rarely seen in the course of iatrogenic immunosuppression, especially in kidney transplantation; OHL is even more rarely seen in immunocompetent hosts. Lesions that clinica
Shoshin beriberi in a patient with human immunodeficiency virus infection [letter]: Intensive Care Med. 1993;19(8):481-2. Unique Identifier : AIDSLINE MED/94124767; Bruneel F; Gachot B; Lucet JC; Bedos JP; Wolff M
Communicable hysteria? [letter; comment]: J Am Dent Assoc. 1994 Jan;125(1):12, 14. Unique Identifier : AIDSLINE MED/94124791; Smith CF
MDR-TB. Another challenge from the microbial world.: J Am Dent Assoc. 1994 Jan;125(1):42-9. Unique Identifier : AIDSLINE MED/94124796; Shearer BG; Beginning in 1985, the long decline in TB cases was dramatically reversed; from 1985 through 1992 reported cases increased 20.1 percent nationally. Two characteristics of this resurgent epidemic are unique: its prevalence among immunocompromised HIV-infected people and the emergence of multidrug-resistant TB. Current
[Two cases of acquired immunodeficiency syndrome with disseminated non-tuberculous mycobacterial infection]: Kansenshogaku Zasshi. 1993 Dec;67(12):1223-7. Unique Identifier : AIDSLINE MED/94124915; Kishihara Y; Nakashima K; Nukina H; Hayashi J; Kashiwagi S; Department of General Medicine, Kyusyu University Hospital.; Two cases of Acquired Immune Deficiency Syndrome (AIDS) with disseminated non-tuberculous mycobacterial infection are reported. Both patients had hemophilia and were infected with Human Immunodeficiency Virus type 1 (HIV) by antihemophilic factor infusion. In case 1, a 44-year-old male, Mycobacterium marinum, which or
Characterization of human immunodeficiency virus type 1-specific cytotoxic T lymphocyte clones isolated during acute seroconversion: recognition of autologous virus sequences within a conserved immunodominant epitope.: J Exp Med. 1994 Feb 1;179(2):463-72. Unique Identifier : AIDSLINE MED/94125027; Safrit JT; Andrews CA; Zhu T; Ho DD; Koup RA; Aaron Diamond AIDS Research Center, New York University School of; Medicine, New York 10016.; Virus-specific cytotoxic T lymphocytes (CTL) are involved in protective immunity to many virus infections. It has recently been shown that CTL are detectable early during primary infection with the primate lentiviruses, human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus. To better characteri
Disseminated human immunodeficiency virus 1 (HIV-1) infection in SCID-hu mice after peripheral inoculation with HIV-1.: J Exp Med. 1994 Feb 1;179(2):513-22. Unique Identifier : AIDSLINE MED/94125032; Kollmann TR; Pettoello-Mantovani M; Zhuang X; Kim A; Hachamovitch M; Smarnworawong P; Rubinstein A; Goldstein H; Department of Microbiology and Immunology, Albert Einstein; College of Medicine, Bronx, New York 10461.; A small animal model that could be infected with human immunodeficiency virus 1 (HIV-1) after peripheral inoculation would greatly facilitate the study of the pathophysiology of acute HIV-1 infection. The utility of SCID mice implanted with human fetal thymus and liver (SCID-hu mice) for studying peripheral HIV-1 infe
Cervicofacial nocardiosis: report of case.: J Oral Maxillofac Surg. 1994 Feb;52(2):188-91. Unique Identifier : AIDSLINE MED/94125258; Seidel JF; Younce DC; Hupp JR; Kaminski ZC; University of Medicine and Dentistry of New Jersey, Newark.
Design and synthesis of peptidomimetic inhibitors of HIV-1 protease and renin. Evidence for improved transport.: J Med Chem. 1994 Jan 21;37(2):215-8. Unique Identifier : AIDSLINE MED/94125417; Smith AB 3rd; Hirschmann R; Pasternak A; Akaishi R; Guzman MC; Jones DR; Keenan TP; Sprengeler PA; Darke PL; Emini EA; et al; Department of Chemistry, University of Pennsylvania, Philadelphia; 19104.
Evaluation of a vitamin-cloaking strategy for oligopeptide therapeutics: biotinylated HIV-1 protease inhibitors.: J Med Chem. 1994 Jan 21;37(2):293-304. Unique Identifier : AIDSLINE MED/94125429; Islam I; Ng KY; Chong KT; McQuade TJ; Hui JO; Wilkinson KF; Rush BD; Ruwart MJ; Borchardt RT; Fisher JF; Department of Medicinal Chemistry, Upjohn Laboratories, Upjohn; Company, Kalamazoo, Michigan 49001.; The outstanding limitations to the oligopeptide as a therapeutic agent are poor oral availability and rapid biliary clearance. To address these concerns a series of eight peptidic HIV-1 protease inhibitors containing the structural segment of the vitamin biotin have
From the Centers for Disease Control and Prevention. HIV prevention practices of primary-care physicians--United States, 1992.: JAMA. 1994 Jan 26;271(4):261-2. Unique Identifier : AIDSLINE MED/94125489
From the Centers for Disease Control and Prevention. HIV transmission between two adolescent brothers with hemophilia.: JAMA. 1994 Jan 26;271(4):262, 264. Unique Identifier : AIDSLINE MED/94125490
Reporting AIDS in New York City [letter; comment]: JAMA. 1994 Jan 26;271(4):273; discussion 274. Unique Identifier : AIDSLINE MED/94125498; Smith PF; Muse AG; Mikl J
Reporting AIDS in New York City [letter; comment]: JAMA. 1994 Jan 26;271(4):273-4. Unique Identifier : AIDSLINE MED/94125499; Haverkos H; Needle R
Ethical, behavioral, and social aspects of HIV vaccine trials in developing countries.: JAMA. 1994 Jan 26;271(4):295-301. Unique Identifier : AIDSLINE MED/94125504; Lurie P; Bishaw M; Chesney MA; Cooke M; Fernandes ME; Hearst N; Katongole-Mbidde E; Koetsawang S; Lindan CP; Mandel J; et al; Center for AIDS Prevention Studies, University of California, San; Francisco 94105.; ISSUE--Several investigators are preparing to conduct efficacy trials of human immunodeficiency virus (HIV) vaccines in the developing world. Failure to adequately address the unique ethical, behavioral, and social issues that surround vaccine testing in that setting will jeopardize the success of these trials and fut
Battlefield transfusions.: JAMA. 1994 Jan 26;271(4):319. Unique Identifier : AIDSLINE MED/94125511; Webster NR; Ward MJ; Armed Services Blood Program Office, Falls Church, VA.
Diarrheal morbidity during the first 2 years of life among HIV-infected infants.: JAMA. 1994 Feb 9;271(6):448-52. Unique Identifier : AIDSLINE MED/94125537; Kotloff KL; Johnson JP; Nair P; Hickman D; Lippincott P; Wilson PD; Clemens JD; Division of Infectious Diseases, University of Maryland School of; Medicine, Baltimore 21201.; OBJECTIVE--To determine the incidence, cause, and patterns of diarrhea during the first 2 years of life among infants infected perinatally with the human immunodeficiency virus (HIV). DESIGN--A cohort study in which infants were enrolled shortly after birth and followed up longitudinally using biweekly surveillance fo
[HTLV-I negative adult T cell leukemia; a case report of acute type]: Rinsho Ketsueki. 1993 Dec;34(12):1550-5. Unique Identifier : AIDSLINE MED/94125547; Kirito K; Shindou H; Chiba N; Tobinai K; Shimoyama M; Kinoshita T; Department of Internal Medicine, Yamanashi Central Hospital.; We described a case of adult T cell leukemia (ATL) not associated with human T-cell leukemia virus type I (HTLV-I), a clinical entity that was first reported by Shimoyama et al. A 79-year-old male was admitted with anorexia and fever in October, 1989. Physical examination revealed marked hepatosplenomegaly and superfi
[Detection of HIV-1 proviral DNA in peripheral leukocytes by AMPLICOR HIV-1 test kit]: Rinsho Byori. 1993 Dec;41(12):1323-7. Unique Identifier : AIDSLINE MED/94125561; Yoshihara N; Fukushima K; Suzuki H; Honda M; Yamazaki S; Fukutake K; Meguro T; Yamada K; AIDS Research Center, National Institute of Health, Shinjuku-ku,; Tokyo.; AMPLICOR HIV-1 test kits, which had been developed as an HIV-1 provirus detection test by PCR method, have been evaluated for its clinical diagnostic application. Sixty-six of HIV-1 antibody positive and 67 of HIV-1 antibody negative blood samples derived from hemophiliacs, who had received blood products, have been t
Ocular manifestations in Japanese patients with human immunodeficiency virus infection.: Jpn J Ophthalmol. 1993;37(3):275-81. Unique Identifier : AIDSLINE MED/94125587; Nagata Y; Fujino Y; Matsumoto S; Nishi M; Ono A; Mochizuki M; Oka S; Kimura S; Shimada K; Eye Clinic, Self Defense Forces Central Hospital, Tokyo, Japan.; The ocular manifestations in 65 Japanese human immunodeficiency virus (HIV)-seropositive patients were examined. Based on the cumulative totals, 22 of the cases had acquired immunodeficiency syndrome (AIDS), 17 had AIDS-related complex (ARC), and 35 were asymptomatic carriers (AC), including 4 AIDS cases who had progr
Prevention of HIV and HBV transmission in general practice [letter; comment]: Med J Aust. 1994 Feb 7;160(3):166. Unique Identifier : AIDSLINE MED/94126020; Reiss-Levy E; Rees BE
Current and future HIV/AIDS clinical research. HIV-related therapy improving--slowly.: Minn Med. 1993 Nov;76(11):17-23. Unique Identifier : AIDSLINE MED/94126039; Henry K; Schwebke K; HIV Program, St. Paul-Ramsey Medical Center.; More than 300,000 cases of AIDS have been reported in the United States since 1981. Despite major scientific advances and much effort, the benefits of treatment have been modest. The variable nature of the human immunodeficiency virus (HIV) and the complexity of the immune system are t
Counseling patients for routine HIV testing AMA guidelines. MMA Committee on Ethics and Medical-Legal Affairs.: Minn Med. 1993 Nov;76(11):25-7. Unique Identifier : AIDSLINE MED/94126040
Aminoglycosides may block HIV replication [news]: Minn Med. 1993 Nov;76(11):42. Unique Identifier : AIDSLINE MED/94126043
Needle exchange programs help prevent AIDS [news]: Minn Med. 1993 Nov;76(11):42. Unique Identifier : AIDSLINE MED/94126044
Host-related DNA sequences are localized in the body of schistosome adults.: Parasitology. 1993 Dec;107 ( Pt 5):519-28. Unique Identifier : AIDSLINE MED/94126274; Irie Y; Iwamura Y; Institute of Basic Medical Sciences, University of Tsukuba,; Ibaraki-ken, Japan.; The localization of host (mouse)-related DNA sequences in the adults and cercariae of Schistosoma japonicum and S. mansoni was examined by in situ hybridization using 32P-labelled probes. The hybridization signals to the sequences of the mouse type C and type A retroviruses were clearly observed in the subtegumental l
Severe pulmonary pneumocystosis in simian acquired immunodeficiency syndrome induced by simian immunodeficiency virus: its characterization by the polymerase-chain-reaction method and failure of experimental transmission to immunodeficient animals.: Parasitol Res. 1993;79(8):624-8. Unique Identifier : AIDSLINE MED/94126392; Furuta T; Fujita M; Mukai R; Sakakibara I; Sata T; Miki K; Hayami M; Kojima S; Yoshikawa Y; Department of Parasitology, University of Tokyo, Japan.; Pneumocystis carinii (Pc) infection was observed in three of five rhesus monkeys infected with simian immunodeficiency virus (SIVmac251). They showed severe symptoms similar to those associated with human acquired immunodeficiency syndrome (AIDS). Histopathology revealed severe pulmonary pneumocystosis in one of three
[Computerized tomography in the study of tuberculosis]: Radiol Med (Torino). 1993 Dec;86(6):820-5. Unique Identifier : AIDSLINE MED/94126500; Valentini G; Forlani S; Zompatori M; Longi R; Servizio TAC, Ospedale Infermi, USL 40 Rimini Nord.; Twenty-five HIV-negative patients with proven tuberculosis were studied; 10 of them had had bacteriologic confirmation, 1 tuberculin conversion, 2 biopsy confirmation and in 12 cases ex juvantibus criteria had been followed. All patients underwent X-ray and CT exams of the chest which were useful for diagnosis, progno
[Bullous pneumopathy and spontaneous pneumothorax. Atypical radiologic patterns of Pneumocystis carinii pneumonia]: Radiol Med (Torino). 1993 Dec;86(6):826-32. Unique Identifier : AIDSLINE MED/94126501; Lazzari Agli L; Viglietta G; Arlotti M; Ciammarughi R; Forlani S; Muratore F; Divisione di Medicina Generale, Ospedale Infermi, Rimini.; Pneumocystis carinii pneumonia (PCP) is certainly the most frequent opportunistic pulmonary infection in AIDS patients. Besides the conventional radiographic features demonstrating bilateral infiltrates and airspace consolidation, atypical radiologic patterns are reported in the literature, which are characterized by
[Tuberculosis in the AIDS era (editorial)]: Rev Epidemiol Sante Publique. 1993;41(6):433-5. Unique Identifier : AIDSLINE MED/94126526; Mlika-Cabanne N; Larouze B
[Prevalence of HIV infection in France before the introduction of early treatment: estimation by back-calculation]: Rev Epidemiol Sante Publique. 1993;41(6):437-46. Unique Identifier : AIDSLINE MED/94126527; Rude N; Costagliola D; Valleron AJ; B3E, INSERM SC4, Faculte de Medecine Saint-Antoine, Universite; Pierre et Marie Curie, Paris, France.; In order to estimate the cumulative number of adults infected with Human Immunodeficiency Virus (HIV) in France , the method of backcalculation was applied. This method assumes that the incubation period is constant over time, but the therapies administered since May 1987 among Acqu
[Analysis of delay in reporting of acquired immunodeficiency syndrome in France]: Rev Epidemiol Sante Publique. 1993;41(6):447-53. Unique Identifier : AIDSLINE MED/94126528; Retel O; Costagliola D; Valleron AJ; INSERM U.263, Faculte de Medecine Saint-Antoine, Universite; Pierre et Marie Curie, Paris, France.; Reporting delays of AIDS cases in France could depend on such factors as geographic area of diagnosis, risk group or time of diagnosis. In order to identify the main sources of heterogeneity and to obtain realistic estimates of the number of diagnosed AIDS cases in France, we take
[Tuberculosis and HIV infection in France]: Rev Epidemiol Sante Publique. 1993;41(6):505-8. Unique Identifier : AIDSLINE MED/94126536; Schwoebel V; Jougla E
[Cryptosporidium parvum in patients with chronic diarrhea and AIDS: diagnosis by means of indirect immunofluorescence with monoclonal antibodies]: Rev Med Chil. 1993 Aug;121(8):923-6. Unique Identifier : AIDSLINE MED/94126602; Weitz JC; Astorga B; Laboratorio de Referencia de Parasitologia, Instituto de Salud; Publica, Santiago de Chile.; The diagnosis of cryptosporidiosis is difficult when oocyst elimination is poor as occurs in AIDS patients. Aiming to improve the diagnosis, 144 fecal samples coming from AIDS patients with diarrhea, were studied using indirect immunofluorescence with anti-Cryptosporidium monoclonal antibodies. The results were compar
[AIDS prevention: increased protection for women (news)]: Schweiz Rundsch Med Prax. 1994 Jan 11;83(2):51. Unique Identifier : AIDSLINE MED/94126629
Survival bonding: a response to stress and work with AIDS.: Soc Work Health Care. 1993;19(1):77-89. Unique Identifier : AIDSLINE MED/94126735; Wade K; Simon EP; Department of Social Work, Columbia Presbyterian Medical Center,; New York, NY 10032.; There is ample literature describing the ongoing stressors and tremendous emotional impact on health care professionals caring for patients with AIDS. This paper is a report of a research study which explored collegial relationships and staff retention to determine factors that reduced staff burnout. The study explore
Evaluation of the genotoxic potential of selected anti-AIDS treatment drugs at clinical doses in vivo in mice.: Toxicol Lett. 1994 Feb 1;70(2):171-83. Unique Identifier : AIDSLINE MED/94126844; Motimaya AM; Subramanya KS; Curry PT; Kitchin RM; Department of Dermatology, CBRC, Harvard Medical School,; Charlestown, MA 02129.; Six anti-AIDS drugs were assessed for in vivo genotoxicity and cytotoxicity at human clinical doses with the mouse bone marrow micronucleus assay. These included four dideoxynucleosides (azidothymidine, dideoxycytidine, dideoxyadenosine, and dideoxyinosine), an anthracycline antibiotic (doxorubicin), and a chelating a
The sexuality connection in reproductive health.: Stud Fam Plann. 1993 Sep-Oct;24(5):269-82. Unique Identifier : AIDSLINE MED/94126853; Dixon-Mueller R; International Women's Health Coalition, New York, NY 10010.; Sexuality and power relations based on gender are relevant to researchers, policymakers, and service providers in the reproductive health field, because they underlie virtually all of the behaviors and conditions that their programs address. Yet, a review of conventional treatments in the demographic and family planni
Leishmania braziliensis causing visceral leishmaniasis in a patient with human immunodeficiency virus infection, identified with the aid of the polymerase chain reaction.: Trans R Soc Trop Med Hyg. 1993 Nov-Dec;87(6):627-8. Unique Identifier : AIDSLINE MED/94126883; Hernandez D; Rodriguez N; Martinez C; Garcia L; Convit J; Department of Medicine, Hospital Vargas, School of Medicine,; Universidad Central de Venezuela, Caracas.; This study describes a male patient with human immunodeficiency virus infection, grade IV-C (oropharyngeal moniliasis and Pneumocystis carinii pneumonia), associated with visceral involvement produced by Leishmania braziliensis which was identified by deoxyribonucleic acid hybridization after the polymerase chain reac
Two cases of cutaneous leishmaniasis in Malawi.: Trans R Soc Trop Med Hyg. 1993 Nov-Dec;87(6):668-70. Unique Identifier : AIDSLINE MED/94126897; Pharoah PD; Ponnighaus JM; Chavula D; Lucas SB; LEPRA Evaluation Project, Chilumba, Malawi.; Leishmaniasis is rarely encountered in southern Africa. Two cases were diagnosed by histopathology in northern Malawi in one year. One was an 18 months old child with negative human immunodeficiency virus 1 (HIV-1) serology and widespread skin lesions; the other an HIV-1 positive a
Clinical features associated with HIV-1 infection in adult patients diagnosed with tuberculosis in Djibouti, Horn of Africa.: Trans R Soc Trop Med Hyg. 1993 Nov-Dec;87(6):676-7. Unique Identifier : AIDSLINE MED/94126902; Rodier GR; Sevre JP; Binson G; Gray GC; Said-Salah; Gravier P; US Naval Medical Research Unit No. 3, Cairo, Egypt.
Characterization of Leishmania isolates from two AIDS patients originating from Valencia, Spain [published erratum appears in Trans R Soc Trop Med Hyg 1994 Jan-Feb;88(1):125]: Trans R Soc Trop Med Hyg. 1993 Nov-Dec;87(6):705-6. Unique Identifier : AIDSLINE MED/94126914; Pratlong F; Reynes J; Dereure J; Baixench MT; Marchou B; Lefebvre M; Janbon F; Laboratoire d'Ecologie Medicale et Pathologie Parasitaire,; Faculte de Medecine, Montpellier, France.
Improved immunogenicity of recombinant vaccinia virus-anchored gp120 lacking gp41.: Vaccine. 1993 Oct;11(13):1280-2. Unique Identifier : AIDSLINE MED/94127076; Jin Y; Giri C; Klutch MJ; Shepp D; Wright SE; Department of Internal Medicine, Texas Tech University Health; Sciences Center.; To produce a vaccine against human immunodeficiency virus-1 with improved immunogenicity, the transmembrane and cytoplasmic tail regions of human immunodeficiency virus-1 were replaced with those of the Vesicular Stomatitis Virus glycoprotein, and cloned into vaccinia virus. This recombinant vaccinia virus, vvE13, was
Oral immunization with recombinant BCG induces cellular and humoral immune responses against the foreign antigen.: Vaccine. 1993 Oct;11(13):1283-90. Unique Identifier : AIDSLINE MED/94127077; Lagranderie M; Murray A; Gicquel B; Leclerc C; Gheorghiu M; Laboratoire du BCG, Institut Pasteur de Paris, France.; It has been shown recently that BCG can be used as a live recombinant vaccine to stimulate immune responses. Proliferative or cytotoxic T-cell responses against several viral proteins such as HIV Gag, Env or Nef were obtained after parenteral immunization with BCG expressing these proteins. Antibody responses were als
[AIDS and the surgical specialties]: Zh Vopr Neirokhir Im N N Burdenko. 1993 Oct-Dec;(4):30-3. Unique Identifier : AIDSLINE MED/94127122; Lalaiants IE; Iurishchev EP; Gadzhieva OA
Total reaction time: a new approach in early HIV encephalopathy?: Acta Neurol Scand. 1993 Nov;88(5):344-8. Unique Identifier : AIDSLINE MED/94127155; Dunlop O; Bjorklund R; Abdelnoor M; Myrvang B; Department of Infectious Diseases, Ullevaal University Hospital,; Oslo, Norway.; In an attempt to develop better methods for diagnosis, screening and serial assessment of HIV-1-associated cognitive/motor complex, we have added a motor component to tests of reaction time, defining the new parameter as total reaction time. Thirty-four non-drug-using, HIV-positive men underwent four different tests o
Anti-neutrophil cytoplasm antibodies in HIV infection.: Adv Exp Med Biol. 1993;336:349-52. Unique Identifier : AIDSLINE MED/94127278; Savige JA; Chang L; Crowe SM; University Department of Medicine, Austin Hospital, Heidelberg,; Victoria, Australia.; Sera from 105 HIV-infected patients were tested for anti-neutrophil cytoplasm antibodies (ANCA) by indirect immunofluorescence (IIF), by specific ELISAs using target proteins of ANCA and by a neutrophil cytoplasm extract ELISA. Forty-four sera were positive. These included 18 positive by IIF, 7 with anti-neutrophil pr
Detection of human T lymphotropic virus type I proviral DNA in fresh cells from ascitic fluid in a patient with adult T-cell leukemia [letter]: Am J Hematol. 1994 Mar;45(3):273-4. Unique Identifier : AIDSLINE MED/94127482; Iwahashi M; Otsuka M; Matsumoto M; Shimotakahara S; Kobayashi N
Factors associated with risk for HIV infection among chronic mentally ill adults.: Am J Psychiatry. 1994 Feb;151(2):221-7. Unique Identifier : AIDSLINE MED/94127576; Kalichman SC; Kelly JA; Johnson JR; Bulto M; Department of Psychiatry and Mental Health Sciences, Medical; College of Wisconsin, Milwaukee 53226.; OBJECTIVE: Chronic mentally ill adults have been found to be at risk for HIV infection. The authors investigated the prevalence of HIV risk behaviors among psychiatric outpatients. Correlates of HIV risk factors and characteristics of patient relationships in which risk occurred were investigated. METHOD: Structured i
Sexual activity and risk of HIV infection among patients with schizophrenia.: Am J Psychiatry. 1994 Feb;151(2):228-32. Unique Identifier : AIDSLINE MED/94127577; Cournos F; Guido JR; Coomaraswamy S; Meyer-Bahlburg H; Sugden R; Horwath E; New York State Psychiatric Institute, NY 10032.; OBJECTIVE: This study sought to determine the frequency and types of sexual behavior among patients with schizophrenia and to assess the behavior with respect to risk of HIV infection. METHOD: Ninety-five inpatients and outpatients with a research diagnosis of schizophrenia underwent a series of face-to-face interview
Mood disorders in HIV infection: prevalence and risk factors in a nonepicenter of the AIDS epidemic.: Am J Psychiatry. 1994 Feb;151(2):233-6. Unique Identifier : AIDSLINE MED/94127578; Perkins DO; Stern RA; Golden RN; Murphy C; Naftolowitz D; Evans DL; Department of Psychiatry, University of North Carolina School of; Medicine, Chapel Hill 27599-7160.; OBJECTIVE: The authors studied the lifetime, initial cross-sectional, and 6-month follow-up prevalence of mood disorders in asymptomatic HIV-infected and uninfected homosexual men who lived in an area with a low prevalence of HIV. They also determined the relationship between current major depression and potential dep
HIV-associated psychosis: a study of 20 cases. San Diego HIV Neurobehavioral Research Center Group.: Am J Psychiatry. 1994 Feb;151(2):237-42. Unique Identifier : AIDSLINE MED/94127579; Sewell DD; Jeste DV; Atkinson JH; Heaton RK; Hesselink JR; Wiley C; Thal L; Chandler JL; Grant I; Department of Psychiatry, School of Medicine, University of; California, San Diego.; OBJECTIVE: Psychosis is an uncommon but serious complication of infection with HIV. This article presents the results of a study of HIV-infected individuals with psychosis. METHOD: The authors evaluated 20 HIV-infected men who had noniatrogenic new-onset psychosis without delirium, current substance abuse, or previous
Personality disorder and HIV disease [letter; comment]: Am J Psychiatry. 1994 Feb;151(2):298-9. Unique Identifier : AIDSLINE MED/94127608; Pergami A; Gala C
AIDS--displaying the global dynamics [editorial]: Am J Public Health. 1994 Feb;84(2):175-7. Unique Identifier : AIDSLINE MED/94127619
Circumcision and sexually transmitted diseases.: Am J Public Health. 1994 Feb;84(2):197-201. Unique Identifier : AIDSLINE MED/94127625; Cook LS; Koutsky LA; Holmes KK; Department of Epidemiology, School of Public Health, University; of Washington, Seattle.; OBJECTIVES. New evidence linking lack of circumcision with sexually transmitted human immunodeficiency virus revives concerns about circumcision and other sexually transmitted diseases. This study was undertaken to assess the relationship between circumcision and syphilis, gonorrhea, chlamydial infection,
Providing medical care to methadone clinic patients: referral vs on-site care [see comments]: Am J Public Health. 1994 Feb;84(2):207-10. Unique Identifier : AIDSLINE MED/94127627; Umbricht-Schneiter A; Ginn DH; Pabst KM; Bigelow GE; Behavioral Pharmacology Research Unit, Johns Hopkins Medical; School, Baltimore, Md.; OBJECTIVES. Intravenous drug users are at high risk for medical illness, yet many are medically underserved. Most methadone treatment programs have insufficient resources to provide medical care. The purpose of this study was to test the efficacy of providing medical care at a methadone clinic site vs referral to anot
AIDS, HIV infection, and illicit drug use within inner-city families and social networks.: Am J Public Health. 1994 Feb;84(2):271-4. Unique Identifier : AIDSLINE MED/94127639; Pivnick A; Jacobson A; Eric K; Doll L; Drucker E; Department of Epidemiology and Social Medicine, Montefiore; Medical Center, Bronx, NY.; OBJECTIVES. Drug use is commonly depicted and treated as an individual problem. This study describes the extent of drug use, human immunodeficiency virus (HIV) infection, and acquired immunodeficiency syndrome (AIDS) among drug users sexual partners and family and household members in order to broaden considerations
Injecting risk behavior among drug users in Amsterdam, 1986 to 1992, and its relationship to AIDS prevention programs.: Am J Public Health. 1994 Feb;84(2):275-81. Unique Identifier : AIDSLINE MED/94127640; van Ameijden EJ; van den Hoek AR; Coutinho RA; Department of Public Health and Environment, Amsterdam, The; Netherlands.; OBJECTIVES. Serial, cross-sectional trends in injecting risk behavior were studied among drug users from 1986 to 1992. METHODS. From a cohort study in Amsterdam, 616 intake visits of drug users who had injected in the 6 months preceding intake were selected. RESULTS. The proportion of drug users who reported borrowing
A pilot syringe exchange program in Washington, DC.: Am J Public Health. 1994 Feb;84(2):303-4. Unique Identifier : AIDSLINE MED/94127648; Vlahov D; Ryan C; Solomon L; Cohn S; Holt MR; Akhter MN; Department of Epidemiology, Johns Hopkins School of Hygiene and; Public Health Baltimore, Md.; The Washington, DC City Council authorized a pilot syringe exchange program to operate for only 60 days at a single drug abuse treatment facility in the District. Only adults on the waiting list for treatment were eligible (n = 467). Of the 33 who enrolled, median duration of drug injection was 18 years. Twenty-seven
Defending HIV seroprevalence surveys [letter; comment]: Am J Public Health. 1994 Feb;84(2):319-20. Unique Identifier : AIDSLINE MED/94127654; Buehler JW; Petersen LR; Ward JW; Valdiserri RO
The efficacy of testing and counseling in limiting HIV transmission [letter; comment]: Am J Public Health. 1994 Feb;84(2):321. Unique Identifier : AIDSLINE MED/94127656; Cohen DA
Selective inactivation of eukaryotic beta-galactosidase in assays for inhibitors of HIV-1 TAT using bacterial beta-galactosidase as a reporter enzyme.: Anal Biochem. 1993 Nov 15;215(1):24-30. Unique Identifier : AIDSLINE MED/94127699; Young DC; Kingsley SD; Ryan KA; Dutko FJ; Department of Virology, Sterling Winthrop Pharmaceuticals; Research Division, Collegeville, Pennsylvania 19426.; Bacterial beta-galactosidase is one of several reporter enzymes used in studying the transcriptional activity of eukaryotic promoters. Although it is one of the easiest and least expensive enzymes to assay, its use has been limited because of its low sensitivity, which is due in part to endogenous levels of beta-galac
Intravenous methylprednisolone in HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP).: Arq Neuropsiquiatr. 1993 Sep;51(3):325-8. Unique Identifier : AIDSLINE MED/94127954; Araujo AQ; Afonso CR; Leite AC; Dultra SV; Unidade de Neuropatias Associadas ao HTLV, Hospital Evandro; Chagas, Fiocruz, Rio de Janeiro RJ, Brasil.; HTLV-I (Human T-lymphotropic virus type I) associated myelopathy/tropical spastic paraparesis (HAM/TSP) is an immunomediated myelopathy induced by the HTLV-I. Some patients, specially those from Japan , seem to have a good response to steroid treatment. However, this has not been fou
Magnetic resonance imaging in HTLV-I associated myelopathy.: Arq Neuropsiquiatr. 1993 Sep;51(3):329-32. Unique Identifier : AIDSLINE MED/94127955; Melo A; Moura L; Rios S; Machado M; Costa G; Federal University of Bahia (UFBA), Salvador.; Magnetic resonance imaging of the brain and spinal cord were carried out for seventeen consecutive patients with HTLV-1 associated myelopathy (HAM). Eight patients had brain abnormalities and four had decreased thoracic spinal cord diameter. Brain lesions were mostly located in subcortical and periventricular areas. O
Factitious acquired immunodeficiency syndrome (AIDS) [letter]: Aust N Z J Med. 1993 Oct;23(5):524. Unique Identifier : AIDSLINE MED/94128012; Munckhof WJ; Jenkins K
Disinfection of impression materials to prevent viral cross contamination: a review and a protocol.: Int J Prosthodont. 1993 Sep-Oct;6(5):480-94. Unique Identifier : AIDSLINE MED/94128187; Owen CP; Goolam R; Department of Prosthetic Dentistry, Faculty of Dentistry,; University of the Western Cape, Mitchells Plain, South Africa.; Hepatitis B and the acquired immunodeficiency syndrome are serious diseases because of their poor prognoses. The increasing awareness of the latter has highlighted the need for adequate precautions against cross contamination. However, the risk to dental personnel is still far higher from hepatitis B than it is from t
Large-scale immunoaffinity purification of recombinant soluble human antigen CD4 from Escherichia coli cells.: Biotechnol Appl Biochem. 1993 Dec;18 ( Pt 3):341-57. Unique Identifier : AIDSLINE MED/94128252; Wells PA; Beiderman B; Garlick RL; Lyle SB; Martin JP Jr; Herberg JT; Meyer HF; Henderson SL; Eckenrode FM; Cancer and Infectious Diseases Research Services, Upjohn Company,; Kalamazoo, MI 49001.; A large-scale immunoaffinity (IA) purification process was developed for the isolation of recombinant soluble antigen CD4 (sCD4) from Escherichia coli fermentations. The monoclonal antibody used for IA purification of sCD4 recognized a conformation-dependent epitope on the surface of domain 1 of CD4. IA chromatography
[Myelopathy associated with HTLV-1: clinical electrophysiologic study]: Neurologia. 1993 Nov;8(9):291-4. Unique Identifier : AIDSLINE MED/94128394; Matsumoto SC; Nakasato O; Kataoka A; Inayoshi S; Okajima T; Tercer Departamento de Medicina Interna, Escuela de Medicina,; Universidad Nacional de Oita, Japon.; Clinical and electrophysiological studies have been performed in 9 cases of HTLV-I associated myelopathy (7 female, 2 male). Spastic paraparesis and neurogenic bladder were present in 8; sensory disturbances were detected only in 4. The conduction velocities of the posterior tibial and sural nerves were reduced in 2 c
Safe sex? Misconceptions, gender differences and barriers among injection drug users: a focus group approach.: AIDS Educ Prev. 1993 Winter;5(4):279-93. Unique Identifier : AIDSLINE MED/94128502; Weiss SH; Weston CB; Quirinale J; Department of Preventive Medicine and Community Health,; University of Medicine & Dentistry of New Jersey-New Jersey; Medical School, Newark 07107.; Heterosexual transmission is one factor involved in the spread of the human immunodeficiency virus (HIV) within the injection drug use (IDU) population and between IDU and non-IDU individuals. Insufficient information is currently available to reduce this heterosexual transmission. As a basis for designing a questionn
Unsafe sex: decision-making biases and heuristics.: AIDS Educ Prev. 1993 Winter;5(4):294-301. Unique Identifier : AIDSLINE MED/94128503; Kaplan BJ; Shayne VT; Department of Psychology, State University of New York, College; at Fredonia.; This paper suggests that continued high-risk behavior is the result of the heuristics used to make judgments under uncertainty, and that the same heuristics may be mobilized to increase the use of safer-sex practices. In order to explain why it is that individuals fail to make effective use of the information they may
AIDS-related reasons for gay men's adoption of celibacy.: AIDS Educ Prev. 1993 Winter;5(4):302-10. Unique Identifier : AIDSLINE MED/94128504; Siegel K; Raveis VH; Memorial Sloan-Kettering Cancer Center, New York.; Since it was first recognized that human immunodeficiency virus (HIV) infection could be sexually transmitted, celibacy has been advocated by some as the only unequivocally effective adaptation for avoiding the risk of infection. Others, however, have countered that few will be willing to be celibate and, further, tha
Gender differences in AIDS-relevant condom attitudes and condom use.: AIDS Educ Prev. 1993 Winter;5(4):311-26. Unique Identifier : AIDSLINE MED/94128505; Sacco WP; Rickman RL; Thompson K; Levine B; Reed DL; Department of Psychology, University of South Florida, Tampa; 33620.; Two studies, conducted approximately one year apart, examined gender differences in AIDS-relevant condom attitudes, condom use behaviors, and relationships among attitudes and condom use behaviors. Subjects (N = 248, N = 528) were undergraduates, primarily heterosexual. Females reported more favorable attitudes, with
An evaluation of a school-based AIDS/HIV education program for young adolescents.: AIDS Educ Prev. 1993 Winter;5(4):327-39. Unique Identifier : AIDSLINE MED/94128506; Newman C; DuRant RH; Ashworth CS; Gaillard G; Department of Medicine, Medical College of Georgia, Augusta; 30912.; This study evaluated the efficacy of a school-based AIDS/human immunodeficiency virus (HIV) education program on 6th and 7th grade students. Using a quasi-experimental pretest-posttest control group design, a control group and an education group (intervention I) received both pretest and posttest questionnaires and a
Young adolescent attitudes toward sex and substance use: implications for AIDS prevention.: AIDS Educ Prev. 1993 Winter;5(4):340-51. Unique Identifier : AIDSLINE MED/94128507; Levy SR; Lampman C; Handler A; Flay BR; Weeks K; Prevention Research Center, University of Illinois at Chicago.; This paper explores differences in adolescents attitudes, beliefs, and resistance skills regarding sexual behaviors and use of substances in the context of AIDS prevention. A total of 553 7th and 8th grade students completed a self-administered questionnaire as baseline data collection for a human immunodeficiency vi
Social network, support and influence: relationships with drug use and protective AIDS behavior.: AIDS Educ Prev. 1993 Winter;5(4):352-66. Unique Identifier : AIDSLINE MED/94128508; Zapka JG; Stoddard AM; McCusker J; School of Public Health, University of Massachusetts at Amherst.; One reason for difficulty in long-term maintenance of behavior changes by injection drug users (IDUs) is the concomitant support or distraction from the IDUs social environment. This study explored the relationship of social factors--e.g., encouragement from friends, beliefs about social norms--with drug injection beh
Kaposi's sarcoma in Italy before and after the AIDS epidemic.: Br J Cancer. 1994 Feb;69(2):333-6. Unique Identifier : AIDSLINE MED/94128529; Geddes M; Franceschi S; Barchielli A; Falcini F; Carli S; Cocconi G; Conti E; Crosignani P; Gafa L; Giarelli L; et al; Servizio di Epidemiologia Descrittiva, Valutativa e di; Cancerogenesi Ambientale, Sezione dell'IST di Genova, Italy.; The incidence of Kaposi s sarcoma (KS) in 1976-90 was assessed in Italy , taking advantage of a network of nine population-based cancer registries covering, at its maximum, approximately 5.6 million subjects. The first examined period (1976-84) substantially reflects the epidemiology
Health hacks borch facts shock!: Nurs Stand. 1993 Nov 24-30;8(10):44. Unique Identifier : AIDSLINE MED/94128553; Smart A
World news. International. Nurses have been awarded scholarships to pursue their education [news]: Nurs Stand. 1993 Dec 1-7;8(11):14. Unique Identifier : AIDSLINE MED/94128559
World news. Thailand. The first large-scale trial of an AIDS vaccine [news]: Nurs Stand. 1993 Dec 1-7;8(11):14. Unique Identifier : AIDSLINE MED/94128560
HIV/AIDS: Sunday morning on the Chain gang.: Nurs Stand. 1993 Dec 1-7;8(11):18-9. Unique Identifier : AIDSLINE MED/94128561; Alderman C
World AIDS Day. Cash to continue, but more demanded [news]: Nurs Stand. 1993 Dec 1-7;8(11):9. Unique Identifier : AIDSLINE MED/94128573; Martell R
Asymptomatic women at high risk of vertical HIV-1 transmission to their fetuses [letter; comment]: Br J Obstet Gynaecol. 1994 Jan;101(1):85. Unique Identifier : AIDSLINE MED/94128711; Nusbaum NJ
[Tuberculous granuloma of the tibia in an HIV patient]: Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 1993 Dec;159(6):572-3. Unique Identifier : AIDSLINE MED/94128996; Steiner P; Christl HW; Albrecht H; Abteilung Rontgendiagnostik, Universitats-Krankenhaus; Hamburg-Eppendorf.
Opsonization and phagocytosis of Cryptococcus neoformans.: Arch Med Res. 1993 Autumn;24(3):211-8. Unique Identifier : AIDSLINE MED/94129171; Kozel TR; Department of Microbiology, School of Medicine, University of; Nevada, Reno 89557.; Cryptococcus neoformans is unique among the pathogenic fungi because the yeast is surrounded by an antiphagocytic polysaccharide capsule. Host resistance to cryptococcosis is dependent on natural defense mechanisms that cope with this essential fungal virulence factor. Recent studies in several laboratories indicate t
GP facilitators and HIV infection [editorial] [see comments]: BMJ. 1994 Jan 1;308(6920):2-3. Unique Identifier : AIDSLINE MED/94129258; Saunders D
Long-term management after splenectomy. Consider HIV infection in thrombocytopenia [letter]: BMJ. 1994 Jan 8;308(6921):133. Unique Identifier : AIDSLINE MED/94129315; Fisher M; Peters B; McBride M; Kitchen V
Who benefits from medical interventions? [editorial; comment]: BMJ. 1994 Jan 8;308(6921):72-4. Unique Identifier : AIDSLINE MED/94129335; Smith GD; Egger M
Epidemic oro-facial Kaposi's sarcoma (eKS)--report on 124 cases.: Eur J Cancer B Oral Oncol. 1993 Jul;29B(3):187-9. Unique Identifier : AIDSLINE MED/94129342; Reichart PA; Langford-Kuntz A; Pohle HD; Abteilung fur Zahnarztliche Chirurgie/Oralchirurgie (Nord),; Freie Universitat Berlin.; Oro-facial epidemic Kaposi s sarcoma (eKS) was observed in 124 patients (123 homo-/bisexual men, average age 37.9 years, and one 35-year-old transsexual patient). Average survival time was 1 year 9 months (range: 3 months 4 years 6 months). 57.3% of the patients had died. The hard and/or soft palate, gingiva and tongu
Spreading the word.: Elder Care. 1993 Nov-Dec;5(6):31. Unique Identifier : AIDSLINE MED/94129566; Crump A
The psychosocial impact of HIV infection in gay men, drug users and heterosexuals. Controlled investigation.: Br J Psychiatry. 1993 Nov;163:651-9. Unique Identifier : AIDSLINE MED/94129948; Gala C; Pergami A; Catalan J; Durbano F; Musicco M; Riccio M; Baldeweg T; Invernizzi G; Department of Psychological Medicine, Chelsea & Westminster; Hospital, Charing Cross and Westminster Medical School,; University of London.; The aim of this study was to establish the prevalence of current and past psychiatric morbidity in HIV seropositive asymptomatic subjects belonging to three transmission categories (gay men, intravenous drug users, and heterosexuals) compared with that found in HIV seronegative controls from the same groups. A cross-s
Tuberculosis and AIDS--a deadly combination [editorial; comment]: Br Vet J. 1993 Sep-Oct;149(5):403-4. Unique Identifier : AIDSLINE MED/94130078; Kitching RP
HIV/AIDS and its implications for the control of animal tuberculosis [see comments]: Br Vet J. 1993 Sep-Oct;149(5):405-17. Unique Identifier : AIDSLINE MED/94130079; Daborn CJ; Grange JM; Centre for Tropical Medicine, Edinburgh University, Easter Bush,; Midlothian.; The HIV/AIDS pandemic is associated with a number of opportunist mycobacterial infections, principally tuberculosis and disease due to the avian tubercle bacillus, Mycobacterium avium. Tuberculosis occurring early in the course of HIV infection is usually caused by M. tuberculosis. However some cases are due to the bo
Pneumocystis carinii choroidopathy and aerosolized pentamidine prophylaxis in a patient with AIDS.: Can J Ophthalmol. 1993 Oct;28(6):291-3. Unique Identifier : AIDSLINE MED/94130199; Lalonde L; Allaire GS; Sebag M; Lamer L; Marcil G; Gervais A; Department of Ophthalmology, Notre-Dame Hospital, Montreal, PQ.
Localization of tumor-reactive lymph node lymphocytes in vivo using radiolabeled monoclonal antibody.: Cancer. 1994 Feb 1;73(3):580-9. Unique Identifier : AIDSLINE MED/94130229; Triozzi PL; Kim JA; Aldrich W; Young DC; Sampsel JW; Martin EW Jr; Department of Medicine, Ohio State University Comprehensive; Cancer Center/Arthur G. James Cancer Hospital and Research; Institute, Columbus.; BACKGROUND. Lymph node lymphocytes vary in their responsiveness to tumor. A technique has been developed that uses radiolabeled monoclonal antibody (MoAb) against the tumor-associated mucin, TAG-72, and a gamma-detecting probe by which lymph nodes containing microscopic tumor and/or shed TAG-72 can be identified in vi
Universal precautions--are we there yet? [editorial]: Compendium. 1993 Apr;14(4):424, 427. Unique Identifier : AIDSLINE MED/94130281; Molinari JA
[AIDS and the eye]: Cesk Oftalmol. 1993 Nov;49(6):387-93. Unique Identifier : AIDSLINE MED/94130350; Cernak A; Filova I; Pont'uchova E; Durcova T; Mokras M; Ocna klinika IVZ, Bratislava.; We are observing a patient who is HIV positive since 1987 and in 1992 he got sick of AIDS. The first ophthalmologist symptom of the illness was a blurred disc margin of the optic nervehead with minor peripapillary hemorrhages and reduction of his visual acuity. After two months the condition of the fundus has improved
The risk of blood splash contamination during angiography.: Clin Radiol. 1994 Jan;49(1):59-60. Unique Identifier : AIDSLINE MED/94130513; McWilliams RG; Blanshard KS; Department of Radiology, St James's University Hospital, Leeds.; Blood splash contamination of the conjunctivae or buccal mucosa may occur during angiography and angioplasty. Since there is a risk of contracting Hepatitis B or HIV via this route, staff should be aware of this potential source of infection. The use of protective masks and goggles or glasses should be considered. We
Interleukin-2 (IL-2) receptor gamma chain mutations in X-linked severe combined immunodeficiency disease result in the loss of high-affinity IL-2 receptor binding.: Eur J Immunol. 1994 Feb;24(2):475-9. Unique Identifier : AIDSLINE MED/94130970; DiSanto JP; Dautry-Varsat A; Certain S; Fischer A; de Saint Basile G; INSERM U132, Hopital Necker-Enfants Malades, Paris, France.; Interactions of interleukin-2 ( IL-2 ) with its high-affinity, heterotrimeric receptor (IL-2R alpha beta gamma) play a pivotal role in the autocrine pathway of T lymphocyte expansion required in an immune response. Mutations in the IL-2R gamma chain-encoding gene have be
Knowing your colleagues can improve health care.: Fla Nurse. 1993 Nov-Dec;41(10):1. Unique Identifier : AIDSLINE MED/94131115; Denker AL
AIDS impact series helps meet the federally mandated OSHA training.: Fla Nurse. 1993 Nov-Dec;41(10):19. Unique Identifier : AIDSLINE MED/94131117
Florida's intervention project for nurses expands to assist HIV infected nurses.: Fla Nurse. 1993 Nov-Dec;41(10):9, 19. Unique Identifier : AIDSLINE MED/94131121
Sialectasis and HIV infection.: Dentomaxillofac Radiol. 1993 Aug;22(3):159-60. Unique Identifier : AIDSLINE MED/94131136; Lamey PJ; Felix D; Nolan A; School of Clinical Dentistry, The Queen's University of Belfast,; Royal Victoria Hospital.; The sialographic findings of the parotid gland of an HIV-positive patient are presented. Multiple areas of sialectasia were noted and their similarity to Sjogren s syndrome is discussed.
Oral hairy leukoplakia in a patient with ulcerative colitis.: Gastroenterology. 1994 Feb;106(2):506-8. Unique Identifier : AIDSLINE MED/94131250; Fluckiger R; Laifer G; Itin P; Meyer B; Lang C; St. Claraspital Basel, Switzerland.; A 30-year-old man with ulcerative colitis developed oral hairy leukoplakia (OHL). Serological examination for human immunodeficiency virus (HIV)-1 and HIV-2 infection showed no abnormalities. Biopsy specimen of the lateral tongue showed ballooned prickle cells, and electron microscopy revealed herpes-type viruses. Imm
Reactive oxygen species, chromosome mutation, and cancer: possible role of clastogenic factors in carcinogenesis.: Free Radic Biol Med. 1994 Jan;16(1):99-109. Unique Identifier : AIDSLINE MED/94131342; Emerit I; Centre National de la Recherche Scientifique, Paris, France.; Superoxide radicals may induce genotoxic effects by indirect action mechanisms, implicating the formation of more long-lived, secondary clastogenic material called chromosome breakage factors or clastogenic factors (CF). CF are produced via the intermediacy of superoxide, and stimulate further superoxide production by
Differential suppression activity induced by paternal leukocyte immunization in habitual abortion.: Gynecol Obstet Invest. 1993;36(4):202-7. Unique Identifier : AIDSLINE MED/94131350; Behar E; Carp H; Livneh A; Gazit E; Tissue Typing Laboratory, Chaim Sheba Medical Center,; Tel-Hashomer, Israel.; In order to investigate the possible role of suppressor cells in paternal leukocyte immunization to prevent recurrent miscarriages, peripheral blood lymphocytes from habitually aborting women before and after immunization were assessed. Immunization-induced suppressor activity as shown by (1) rise in CD8-positive cell
Neuropathologic analysis of postmortal brain samples of HIV-seropositive and -seronegative i.v. drug addicts.: Forensic Sci Int. 1993 Nov;62(1-2):101-5. Unique Identifier : AIDSLINE MED/94131367; Gosztonyi G; Schmidt V; Nickel R; Rothschild MA; Camacho S; Siegel G; Zill E; Pauli G; Schneider V; Institut fur Neuropathologie, Berlin, Germany.; Between 1987 and 1992 we performed forensic-pathologic and neuropathologic examinations on 70 cases of i.v. drug addicts who died of an overdose. In almost 25% of the cases HIV-positivity was revealed by serological examinations. In all the cases, irrespective of the result of the serological examination, a diffuse, r
Drug-related death--an update.: Forensic Sci Int. 1993 Nov;62(1-2):121-8. Unique Identifier : AIDSLINE MED/94131371; Puschel K; Institut fur Rechtszmedizin, Universitat Hamburg, Germany.; Some epidemiological, morphological and toxicological aspects from a continuous prospective study of drug-related fatalities in Hamburg are described. The lethal risk for intravenous drug addicts (IVDA) has increased (1990: n = 136 drug-related fatalities in Hamburg; 1991: n = 184). Infectious diseases are common. Fro
Drug death autopsies at the Munich Institute of Forensic Medicine (1981-1992).: Forensic Sci Int. 1993 Nov;62(1-2):135-9. Unique Identifier : AIDSLINE MED/94131373; Penning R; Fromm E; Betz P; Kauert G; Drasch G; von Meyer L; Institut fur Rechtsmedizin der Universitat Munchen, Germany.; A total of 638 drug death autopsy cases in southern Bavaria from 1981 to 1992 were analysed, including epidemiological and toxicological investigations. The rate of HIV infections decreased during the last few years. Cocaine does not (yet) play a major role. Suicide rates are high. Heroin intoxications are the most fr
A survey of drug deaths in western Austria.: Forensic Sci Int. 1993 Nov;62(1-2):141-6. Unique Identifier : AIDSLINE MED/94131374; Battista HJ; Rossler H; Haller R; Kohler H; Riemer Y; Henn R; Hinterhuber H; Institute of Forensic Medicine, University of Innsbruck, Austria.; We evaluated the drug deaths in western Austria during the period from 1981 to 1991. The increase of fatal cases is partly due to a change in statistical methods and the definition of drug victims . In this paper a survey is given concerning the drug deaths investigated forensica
Preliminary results of an interdisciplinary survey of drug victims.: Forensic Sci Int. 1993 Nov;62(1-2):147-9. Unique Identifier : AIDSLINE MED/94131375; Keul HG; Schafer V; Lorcher U; Schneider M; Lutz FU; Reuhl J; Senckenbergisches Zentrum der Pathologie, Johann Wolfgang; Goethe-Universitat, Frankfurt am Main, Germany.; In an interdisciplinary study, 53 cases of drug-related death were investigated. Forty per cent of these cases exhibited acute or chronic hepatitis; foreign body granulomas were detected in 30%. By CT-scan of the left lung, small abscesses and pneumonic focuses could be localized. The spectrum of bacterial strains iso
Drugs and AIDS in Southeast-Asia.: Forensic Sci Int. 1993 Nov;62(1-2):15-28. Unique Identifier : AIDSLINE MED/94131376; Poshyachinda V; Institute of Health Research, Chulalongkorn University, Bangkok,; Thailand.; Opium dependence was indigenous to countries in the Golden Triangle area in south-east Asia (SA). Heroin epidemics developed in most SA countries in the 1960s and early 1970s and remained a significant problem particularly in Myanmar , Thailand
Undetected drug addict fatalities.: Forensic Sci Int. 1993 Nov;62(1-2):157-9. Unique Identifier : AIDSLINE MED/94131378; Schulz-Schaeffer W; Elwers W; Schmoldt A; Universitat Hamburg, Institut fur Rechtsmedizin, Germany.; A urine screening in fatalities with an unnatural or unknown cause of death (13-40 years of age) was carried out to evaluate the proportion of undetected drug-related cases. Ten out of 160 fatalities without a hint of drug consumption were classified as drug-related according to the definition of the Bundeskriminalamt
Comparison of drug abuse fatalities and emergencies.: Forensic Sci Int. 1993 Nov;62(1-2):161-6. Unique Identifier : AIDSLINE MED/94131379; Schulz-Schaeffer W; Schmoldt A; Peters T; Puschel K; Universitat Hamburg, Institut fur Rechtsmedizin, Germany.; During a 9-month period, drug abuse emergencies were investigated prospectively and compared with drug-related fatalities of the same period. The emergency patients were of younger age, the proportion of women and the prevalence of infections with HIV, HBV and HCV was higher than in drug-related deaths. Additional alc
Basic concepts of treatment and rehabilitation of drug dependence and how they are counteracted by the legalizing debate.: Forensic Sci Int. 1993 Nov;62(1-2):49-55. Unique Identifier : AIDSLINE MED/94131382; Schuler S; Bezirkskrankenhaus Parsberg II, Fachklinik fur Junge; Drogenabhangige, Germany.; Basic treatment of drug dependent patients begins with detoxification and diagnosis of drug related and drug induced diseases. The therapeutic approach has to be oriented on the career of drug addiction itself and constitutional psychopathology. Patients must undergo specialized care if the drug dependence is complica
Methadone-substitution and driving ability.: Forensic Sci Int. 1993 Nov;62(1-2):63-6. Unique Identifier : AIDSLINE MED/94131384; Rossler H; Battista HJ; Deisenhammer F; Gunther V; Pohl P; Prokop L; Riemer Y; Innsbruck University Clinic of Psychiatry, Austria.; A general statement about the driving ability of HIV-positive as well as HIV-negative addicts undergoing methadone-substitution treatment cannot be made with certainty. Even isolated observations are not significant; only an individually performed assessment, free of prejudice and conscientiously done is decisive. The
Correlation between disease and community: is drug addiction a problem of fringe groups?: Forensic Sci Int. 1993 Nov;62(1-2):67-72. Unique Identifier : AIDSLINE MED/94131385; Baumgarten R; 2nd Medical Division, County Hospital Prenzlauer Berg, Berlin,; Germany.; Addiction, because of its associated psychological and physical diseases, is producing increasing expenses through social burden and influencing the epidemiological situation of the whole population via sexual or simple intimate social contacts. Outstanding infectious diseases with a high incidence in drug addicts are
HIV prevalence and risk behaviour in injecting drug users in Berlin.: Forensic Sci Int. 1993 Nov;62(1-2):73-81. Unique Identifier : AIDSLINE MED/94131386; Stark K; Muller R; Institut fur Medisinische Statistik und; Informationsverarbeitung, Freie Universitat Berlin, Germany.; In injecting drug users (IDU) newly entering drug treatment centres in Berlin, HIV seroprevalence continuously decreased from 1985 through 1992. A recent cross-sectional study with multi-site sampling (n = 472) showed significantly differing HIV prevalences by site of recruitment (treatment centres 6%, storefront unit
Preventing the spread of HIV among Australian injecting drug users.: Forensic Sci Int. 1993 Nov;62(1-2):83-7. Unique Identifier : AIDSLINE MED/94131387; Wodak A; Alcohol and Drug Service, St. Vincent's Hospital, Darlinghurst,; Australia.; Control of HIV infection among and from injecting drug users is critical for the long-term control of HIV infection in Australia . There is now consistent and strong evidence that the prevalence of HIV infection among Australian injecting drug users is still low. Recent evidence
HIV-1 prevalence among drug deaths--a multicenter study.: Forensic Sci Int. 1993 Nov;62(1-2):89-93. Unique Identifier : AIDSLINE MED/94131388; Lockemann U; Puschel K; Institute of Forensic Medicine, University of Hamburg, Germany.; Since 1985 several European Institutes of Forensic Medicine have cooperated in a multicenter study providing a constant monitoring of HIV-1 prevalence among drug-related deaths. From 1985 to 1991 the HIV status of 5372 drug-related fatalities (4328 males, 1044 females) has been tested. A total of 764 (14%) drug deaths
Differences between the course of the drug addict's HIV infection and that of other HIV-infected patients.: Forensic Sci Int. 1993 Nov;62(1-2):95-9. Unique Identifier : AIDSLINE MED/94131390; Golz J; Drug addicts have, in general, a less complicated course of HIV infection than homosexual HIV patients. They show fewer opportunistic infections and tumors. But this advantage is lost by unnecessary complications due to their psychic disorders. Their non-compliance and concealment of signs of disease lead to worse out
Non-neoplastic, cutaneous and mucocutaneous manifestations of HIV infection.: Histopathology. 1993 Oct;23(4):297-305. Unique Identifier : AIDSLINE MED/94131418; Francis N; Charing Cross and Westminster Medical School, Department of; Histopathology, London, UK.
Casual sexual experience abroad in patients attending an STD clinic and at high risk for HIV infection.: Genitourin Med. 1994 Feb;70(1):12-4. Unique Identifier : AIDSLINE MED/94131449; Tveit KS; Nilsen A; Nyfors A; Haukeland University Hospital, Bergen, Norway.; OBJECTIVE--To study possible import routes of HIV infection to Norway (by obtaining information on casual sexual contacts abroad from patients attending an STD clinic), and to assess their behavioural risk factors (such as alcohol intake, use of condom) for HIV infection. DESIGN AN
Rectal spirochaetosis in homosexual men: the association with sexual practices, HIV infection and enteric flora.: Genitourin Med. 1994 Feb;70(1):26-9. Unique Identifier : AIDSLINE MED/94131452; Law CL; Grierson JM; Stevens SM; Sexual Health Centre, Sydney Hospital, Australia.; OBJECTIVE--To determine the prevalence of rectal spirochaetosis in homosexual men attending a sexually transmissible diseases clinic and investigate the association between their presence and sexual practices, HIV infection and enteric flora. DESIGN--The study included 144 male homosexual subjects who each completed a
Urinary tract infection in men with AIDS.: Genitourin Med. 1994 Feb;70(1):30-4. Unique Identifier : AIDSLINE MED/94131454; De Pinho AM; Lopes GS; Ramos-Filho CF; Santos O da R; De Oliveira MP; Halpern M; Gouvea CA; Schechter M; Departamento de Medicina Preventiva, Hospital Universitario; Clementino Fraga Filho, Universidade Federal do Rio de Janeiro,; Brasil.; OBJECTIVE--To investigate whether bacteriuria and, specifically, symptomatic urinary tract infection (UTI) occur with increased frequency in men with HIV infection. METHODS--In this cross-sectional study we investigated three groups of men, aged from 18 to 50 years. Group A was composed of patients with a diagnosis of
Recurrent pseudomembranous colitis due to Clostridium difficile in AIDS [clinical conference]: Genitourin Med. 1994 Feb;70(1):51-5. Unique Identifier : AIDSLINE MED/94131459; Churchill DR; Lucas SB; Williams I; Foley NM; Miller RF; Department of Medicine, Middlesex Hospital, London.
AIDS, memory and the history of medicine: musings on the Canadian response.: Genitourin Med. 1994 Feb;70(1):64-9. Unique Identifier : AIDSLINE MED/94131461; Duffin J; Hannah Chair History of Medicine Queen's University, Kingston; Ontario, Canada.; This paper presents the history of AIDS in Canada with special attention to epidemiology, public policy, and social commentary. The interest in medical history sparked by the epidemic is studied in relation to its impact on public health measures. Conversely, the impact of the dise
Genital ulcer disease: accuracy of clinical diagnosis and strategies to improve control in Durban, South Africa.: Genitourin Med. 1994 Feb;70(1):7-11. Unique Identifier : AIDSLINE MED/94131462; O'Farrell N; Hoosen AA; Coetzee KD; van den Ende J; City Health STD Department, King Edward VIII Hospital, Durban,; South Africa.; OBJECTIVE--To investigate the accuracy of clinical diagnosis in genital ulcer disease (GUD); to devise management strategies for improving the control of GUD and thereby limit the spread of HIV-1 infection. DESIGN--Clinical and microbiological assessment of GUD in men and women. The index of suspicion, diagnostic accu
Prevalence of antibodies to HPV16-E7-protein does not differ between AIDS-patients with and without Kaposi's sarcoma [letter]: Genitourin Med. 1994 Feb;70(1):70-1. Unique Identifier : AIDSLINE MED/94131463; Gross G; Pfister H; Wagner B; Brockmeyer N
HIV seroprevalence among eunuchs [letter]: Genitourin Med. 1994 Feb;70(1):71-2. Unique Identifier : AIDSLINE MED/94131465; Lakshmi N; Kumar AG
A non-lymphoma idiotype is indicative and predictive for B cell malignancies in AIDS.: Hybridoma. 1993 Oct;12(5):529-37. Unique Identifier : AIDSLINE MED/94131484; Herndier B; McGrath M; Abbey N; Wang HT; Ng V; Dorigo O; Kaplan L; Muller S; Kohler H; Department of Pathology, San Francisco General Hospital,; University of California.; The 1F7 idiotype previously defined (J Immunol 147:933;1991 and Eur J Immunol 22:1749;1992) is expressed on antibodies reactive to different proteins of HIV (gp41, p24, gp120). Since serum levels of 1F7 (IgM or IgG) are significantly higher in patients with HIV lymphoma as opposed to HIV-infected individuals, normal c
Human immunodeficiency virus type 1 infection of human macrophages modulates the cytokine response to Pneumocystis carinii.: Infect Immun. 1994 Feb;62(2):644-50. Unique Identifier : AIDSLINE MED/94131601; Kandil O; Fishman JA; Koziel H; Pinkston P; Rose RM; Remold HG; Division of Pulmonary and Critical Medicine, New England; Deaconess Hospital, Boston, Massachusetts.; The present studies examined production of the cytokines tumor necrosis factor alpha (TNF-alpha), interleukin-1 beta (IL-1 beta), and IL-6 by human monocyte-derived macrophages exposed to Pneumocystis carinii in vitro and the impact of concurrent macrophage infection with human immunodeficiency virus type 1 (HIV-1) on
Plasma fibronectin concentrations in patients with HIV infection and visceral leishmaniasis.: Infection. 1993 Sep-Oct;21(5):303-5. Unique Identifier : AIDSLINE MED/94131630; Rodriguez-Cuartero A; Nunez-Carrill J; Salas-Galan A; Rodriguez-Rodriguez MA; Dept. of Internal Medicine, Granada University, Spain.; Concentrations of circulating fibronectin were studied in plasma of 22 patients with acquired immunodeficiency syndrome and 24 healthy blood donors. There were significant differences between the plasma fibronectin values of the patient population with AIDS (mean 2 SD = 206 +/- 86 mg/l) and of the control group (mean
Tuberculous pericarditis as the first manifestation of AIDS.: Infection. 1993 Sep-Oct;21(5):334-5. Unique Identifier : AIDSLINE MED/94131638; Pedro-Botet J; Auguet T; Coll J; Pons S; Rubies-Prat J; Dept. of Medicine, Hospital del Mar, Universidad Autonoma de; Barcelona, Spain.; Although it is known that extrapulmonary tuberculosis in patients with AIDS has a broad spectrum of clinical manifestations, pericardial involvement has rarely been described. We report a case of this condition as the first manifestation of AIDS with good response to antituberculous therapy. Although unusual, the diag
Identification of the microsporidian parasite, Enterocytozoon bieneusi in faecal samples and intestinal biopsies from an AIDS patient.: Int J Parasitol. 1993 Sep;23(6):793-801. Unique Identifier : AIDSLINE MED/94131675; Lumb R; Swift J; James C; Papanaoum K; Mukherjee T; Division of Clinical Microbiology, Institute of Medical and; Veterinary Science, Adelaide, South Australia.; The microsporidian parasite, Enterocytozoon bieneusi, is currently recognized as a potentially important cause of chronic diarrhoea in patients infected with the human immunodeficiency virus (HIV). Faecal concentrates from a 38-year-old, HIV-seropositive patient examined by light and electron microscopy revealed the p
Herpes simplex encephalitis: a diagnostic and therapeutic reapprisal [see comments]: J Assoc Physicians India. 1993 May;41(5):277-8. Unique Identifier : AIDSLINE MED/94131875; Satishchandra P; Nandini M; Shankar SK; Vasudevarao T; Ravi V; Shenoy PK; Chatterjee S; Jain S; Department of Neurology, National Institute of Mental Health &; Neuro Sciences (NIMHANS), Bangalore.; Herpes Simplex Encephalitis (HSE) appears to be underdiagnosed in India , though viral encephalitides constitutes an important entity with significant morbidity. With an upsurge in AIDS, HSE may perhaps emerge as an important opportunistic infection in future. We discuss the clinical
HIV--science, politics, and policy: what have we learned?: J Clin Apheresis. 1993;8(3):155-60; discussion 181-6. Unique Identifier : AIDSLINE MED/94131980; Gebbie K; Washington State Department of Health, Olympia.
HIV infection at home and in the workplace.: J Clin Apheresis. 1993;8(3):161-7; discussion 181-6. Unique Identifier : AIDSLINE MED/94131981; Evatt B; Division of Immunologic, Oncologic, and Hematologic Diseases,; Centers for Disease Control, Atlanta, Georgia.; Major questions have been raised concerning an individual s risk for contracting HIV infection when they come into contact with a patient who has AIDS in the home and/or workplace. Specific concerns are addressed and guidelines are reviewed.
New trends in HIV/AIDS epidemiology.: J Clin Apheresis. 1993;8(3):174-7; discussion 181-6. Unique Identifier : AIDSLINE MED/94131983; Lafferty WE; Office of Epidemiology and Surveillance, HIV/AIDS and Infectious; Diseases, Washington State Department of Health, Seattle.; World geographic patterns of HIV infection are discussed. Various parameters such as age, route of transmission, exposure, culture, and geographical influences are addressed. Future trends for HIV infection and development of AIDS and associated disorders such as non-Hodgkin s lymphoma
What does the future hold for patients infected with HIV?: J Clin Apheresis. 1993;8(3):178-80; discussion 181-6. Unique Identifier : AIDSLINE MED/94131984; Fields M; Washington State Department of Health, Olympia.
Knee replacement in haemophilia [letter; comment]: J Bone Joint Surg Br. 1994 Jan;76(1):165-6. Unique Identifier : AIDSLINE MED/94132117; Birch NC; Ribbans WJ; Goldman E; Lee CA
Cytokine involvement in viral permissiveness and the progression of HIV disease.: J Cell Biochem. 1993 Dec;53(4):336-42. Unique Identifier : AIDSLINE MED/94132199; Butera ST; Retrovirus Diseases Branch, Centers for Disease Control and; Prevention, Atlanta, Georgia 30333.; Many viruses have evolved novel means of exploiting host defense mechanisms for their own survival. This exploitation may be best exemplified by the interrelationships between certain viruses and the host cytokine networks. Many viruses, including the human immunodeficiency virus type-1 (HIV-1), rely on the liberation
AIDS: human rights and responsibilities.: Hosp Pract (Off Ed). 1994 Feb 15;29(2):155-7, 161-4. Unique Identifier : AIDSLINE MED/94132212; Bayer R; Division of Sociomedical Sciences, Columbia University School of; Public Health, New York.; As epidemiology changes and new therapies emerge, the focus of disease control is shifting from the voluntary to the mandatory. This is reflected in debates about routine HIV testing of newborns and the confidentiality of HIV-infected adults. Other issues include access to unproven drugs, the problems posed by co-infe
The basic nature of ethical problems experienced by persons with acquired immunodeficiency syndrome: implications for nursing ethics education and practice.: J Prof Nurs. 1993 Nov-Dec;9(6):327-35. Unique Identifier : AIDSLINE MED/94132436; Cameron ME; Crisham P; Lewis DE; School of Nursing, University of Minnesota, Minneapolis.; The purpose of this research was to describe and examine the basic nature of ethical problems that are experienced by persons with acquired immunodeficiency syndrome (AIDS). The participants were 25 persons with AIDS and 5 significant persons, not infected with the human immunodeficiency virus, who provided contextual
Hepatic amyloidosis in intravenous drug abusers and AIDS patients.: J Hepatol. 1993 Aug;19(1):79-84. Unique Identifier : AIDSLINE MED/94132524; Osick LA; Lee TP; Pedemonte MB; Jacob L; Chauhan P; Navarro C; Comer GM; Department of Medicine, Harlem Hospital Center, New York, NY; 10037.; The clinical and pathological features of four liver biopsies and 12 autopsies from 1981-1990 with hepatic amyloidosis were reviewed. All of the patients had a history of both intravenous and subcutaneous cocaine and heroin use with chronic suppurative skin ulcers. Five patients were proven to have the acquired immuno
Presence of HIV-1 in human parenchymal and non-parenchymal liver cells in vivo.: J Hepatol. 1993 Sep;19(2):252-8. Unique Identifier : AIDSLINE MED/94132538; Housset C; Lamas E; Courgnaud V; Boucher O; Girard PM; Marche C; Brechot C; INSERM U-370, Paris, France.; The infection of liver cells by HIV-1 was investigated in vivo. Liver biopsies from 13 anti-HIV-1 antibody-positive patients were studied and HIV-1 DNA was revealed by polymerase chain reaction (PCR) in eight. In situ hybridization demonstrated the presence of HIV-1 RNA in all eight PCR-positive liver specimens. Monon
The minitel: the glittering future of a new invention.: J Homosex. 1993;25(1-2):193-203. Unique Identifier : AIDSLINE MED/94132560; Duyves M; University of Amsterdam, The Netherlands.; In the eighties a new medium has found its way in French society: the minitel. It has influenced gay communication immediately, heavily and constantly. The role of the minitel in the gay world of the eighties is gone into. Some ideas are put forward as to why the minitel has been so successful in
The evolution of the AIDS illness and the polarisation of values.: J Homosex. 1993;25(3):293-305. Unique Identifier : AIDSLINE MED/94132571; Da Silva LL; Ecole des Hautes Etudes en Sciences Sociales, Paris.; This article is based on a study carried out in Sao Paolo, Brazil , from 1983 to 1986 among male homosexuals. It deals with the various practices and life-styles which constitute the homosexual world in Sao Paulo, and questions regarding AIDS. An analysis is made of the contrasting
Homosexual rituals and safer sex.: J Homosex. 1993;25(3):307-17. Unique Identifier : AIDSLINE MED/94132572; Pollak M; Centre National de la Recherche Scientifique, Paris.
Homosexuals and AIDS: a new approach to the illness.: J Homosex. 1993;25(3):319-27. Unique Identifier : AIDSLINE MED/94132573; Vandevyer C; University of Louvain, Belgium.; AIDS, historically connected with homosexuals, has provoked a number of social, psychological, and moral reactions within the homosexual community itself as well as elsewhere. Among questions raised, there are all those concerning the meaning and place of human sexuality. Between strict moral condemnation and publicit
A monoclonal antibody that recognizes HLA-B27 in the context of peptides.: J Immunol. 1994 Feb 1;152(3):1197-205. Unique Identifier : AIDSLINE MED/94132615; Wang J; Yu DT; Fukazawa T; Kellner H; Wen J; Cheng XK; Roth G; Williams KM; Raybourne RB; Department of Medicine, University of California Los Angeles; 90024.; The T2 mutant cell line is unable to load peptides into the MHC class I Ags inside the cells. These empty MHC class I Ags are not expressed on the cell surface unless the cells are cultured at low temperatures. Expression will occur at 37 degrees C only in the presence of peptides that bind to and stabilize the class
Analysis of mutant HLA-A2 molecules. Differential effects on peptide binding and CTL recognition.: J Immunol. 1994 Feb 1;152(3):1213-21. Unique Identifier : AIDSLINE MED/94132617; Tussey LG; Matsui M; Rowland-Jones S; Warburton R; Frelinger JA; McMichael A; Institute of Molecular Medicine, John Radcliffe Hospital, Oxford,; UK.; Previous studies have identified several residues lining the groove of the HLA-A2.1 molecule that are critical for Ag presentation. However, it is not clear whether these residues are critical for binding of the peptide epitope per se or for determining the appropriate conformation of bound peptide. To distinguish bet
The immune response to Histoplasma capsulatum: unearthing its secrets.: J Lab Clin Med. 1994 Feb;123(2):201-5. Unique Identifier : AIDSLINE MED/94132704; Deepe GS Jr; Department of Medicine, University of Cincinnati College of; Medicine, OH 45267-0560.
gp120 HIV envelope glycoprotein increases the production of nitric oxide in human monocyte-derived macrophages.: J Leukoc Biol. 1994 Feb;55(2):175-82. Unique Identifier : AIDSLINE MED/94132723; Pietraforte D; Tritarelli E; Testa U; Minetti M; Department of Cell Biology, Istituto Superiore di Sanita, Rome,; Italy.; The effect of recombinant gp120 HIV envelope glycoprotein on the generation of free radicals by monocyte-derived macrophages (MDM) was measured by EPR spin trapping with 5,5-dimethyl-1-pyrroline-N-oxide (DMPO). After 1 day in culture, MDM produced a spin trap adduct of DMPO with hyperfine splitting constants superimpo
Involvement of CD4 in interleukin-6 secretion by U937 monocytic cells stimulated with the lectin jacalin.: J Leukoc Biol. 1994 Feb;55(2):214-20. Unique Identifier : AIDSLINE MED/94132728; Taimi M; Dornand J; Nicolas M; Marti J; Favero J; INSERM U65, Universite Montpellier II, Sciences et Techniques du; Languedoc, France.; The lectin jacalin is mitogenic for CD4 expressing T lymphocytes, interacts with the CD4 molecule, and inhibits HIV infection of CD4+ cells. In the present study the effect of jacalin was tested on cells from the monocyte/macrophage lineage that also express the CD4 molecule. We used CD4+ promyelomonocytic U937 cells
Acute diffuse leukoencephalitis in HIV-1 infection.: J Neurol Neurosurg Psychiatry. 1994 Jan;57(1):105-7. Unique Identifier : AIDSLINE MED/94132807; Luer W; Gerhards J; Poser S; Weber T; Felgenhauer K; Department of Neurology, Georg-August University, Gottingen,; Germany.; The clinical, neuroradiological, and cerebrospinal fluid findings of a case with acute diffuse leukoencephalitis, a demyelinating disease associated with human immunodeficiency virus infection of the brain, is reported. The patient presented with acute tetraparesis as the primary manifestation of a previously symptom
Immunohistochemical changes and PCR detection of HIV provirus DNA in brains of asymptomatic HIV-positive patients.: J Neuropathol Exp Neurol. 1994 Jan;53(1):43-50. Unique Identifier : AIDSLINE MED/94132839; Sinclair E; Gray F; Ciardi A; Scaravilli F; Department of Neuropathology, National Hospital, London, Great; Britain.; The stage of HIV infection at which the virus enters the nervous system remains poorly understood. Examination of brains of HIV-positive non-AIDS patients often shows lymphocytic meningitis, myelin pallor and gliosis, but no immunohistochemical (IHC) evidence of the virus. In this study we have examined a number of br
Cytokine expression in the spinal cord lesions in HTLV-I-associated myelopathy.: J Neuropathol Exp Neurol. 1994 Jan;53(1):72-7. Unique Identifier : AIDSLINE MED/94132842; Umehara F; Izumo S; Ronquillo AT; Matsumuro K; Sato E; Osame M; Third Department of Internal Medicine, Faculty of Medicine,; Kagoshima University, Japan.; Immunocytochemical staining of spinal cords from five autopsied patients with HTLV-I-associated myelopathy/tropical spastic paraparesis was performed using a panel of monoclonal or polyclonal antibodies reactive with interleukin-1 beta (IL-1 beta), interleukin-6 (IL-6), tumor necrosis factor (TNF)-alpha, interferon (I
HIV antigen and DNA in AIDS spinal cords correlate with macrophage infiltration but not with vacuolar myelopathy.: J Neuropathol Exp Neurol. 1994 Jan;53(1):86-94. Unique Identifier : AIDSLINE MED/94132844; Petito CK; Vecchio D; Chen YT; Department of Pathology, New York Hospital-Cornell University; Medical College, New York.; Since the relationship between vacuolar myelopathy (VM) and HIV infection of the spinal cord is unclear, we studied 74 cases of VM in AIDS patients for associated spinal cord and brain diseases, the presence of HIV antigens (n = 54) and amplified DNA (n = 7) and serum levels of vitamin B12 and folic acid (n = 6). Necr
Implementation of a customized needleless intravenous delivery system.: J Intraven Nurs. 1993 Nov-Dec;16(6):339-44. Unique Identifier : AIDSLINE MED/94132955; Terrell F; Williams B; Occupational exposure to human immunodeficiency virus (HIV), hepatitis, and other bloodborne pathogens concerns all health care workers, especially those in high-risk clinical settings such as the emergency room, operating room, intravenous therapy department, etc. In response to the increased attention to needlestick
DNA cleavage, antiviral and cytotoxic reactions photosensitized by simple enediyne compounds.: J Photochem Photobiol B. 1993 Dec;21(2-3):135-42. Unique Identifier : AIDSLINE MED/94132958; Kagan J; Wang X; Chen X; Lau KY; Batac IV; Tuveson RW; Hudson JB; Department of Chemistry, University of Illinois at Chicago; 60607-7061.; Very potent antibiotic antitumor natural products contain a enediyne moiety which, upon thermal activation, is capable of abstracting hydrogens from DNA. 1,6-Diphenyl-3-hexene-1,5-diyne was selected as a candidate for inducing DNA strand breaks photochemically. Easily interconverted with light, both geometric isomers
Varicella in children with perinatally acquired human immunodeficiency virus infection.: J Pediatr. 1994 Feb;124(2):271-3. Unique Identifier : AIDSLINE MED/94132986; Kelley R; Mancao M; Lee F; Sawyer M; Nahmias A; Nesheim S; Department of Pediatrics, Emory University School of Medicine,; Atlanta, GA 30303.; Thirteen children with human immunodeficiency virus infection acquired perinatally and with varicella were identified. Clinical and epidemiologic information, including the use of varicella immune globulin and acyclovir , was obtained and testing for antibodies to varicella-zoste
Evaluation of autoantibodies to brain proteins in patients with AIDS dementia complex.: J Acquir Immune Defic Syndr. 1994 Feb;7(2):103-8. Unique Identifier : AIDSLINE MED/94133077; Trujillo JR; Navia B; McLane MF; Worth JL; Lee TH; Essex M; Department of Cancer Biology, Harvard School of Public Health,; Boston, MA 02115.; A high frequency of autoantibodies to brain proteins has been reported in HIV-1-positive patients. However, the specificity of this response has not been characterized. Using homogenized tissue from three normal brains, the presence of autoantibodies to human brain proteins was analyzed in 16 HIV-1-positive patients w
Differential expression of tumor necrosis factor alpha and interleukin 1 beta compared with interleukin 6 in monocytes from human immunodeficiency virus-positive individuals measured by polymerase chain reaction.: J Acquir Immune Defic Syndr. 1994 Feb;7(2):109-15. Unique Identifier : AIDSLINE MED/94133078; Lathey JL; Kanangat S; Rouse BT; Department of Pediatrics, University of California, San Diego, La; Jolla 92093-0672.; Expression of tumor necrosis factor alpha (TNF alpha), interleukin 1 beta (IL-1 beta), and interleukin 6 (IL-6) was evaluated in unstimulated peripheral blood monocytes obtained from human immunodeficiency virus-positive (HIV+) individuals using a reverse transcription-polymerase chain reaction (RT-PCR) method. In all
CD4-modified synthetic peptides containing phenylalanine inhibit HIV-1 infection in vitro.: J Acquir Immune Defic Syndr. 1994 Feb;7(2):129-34. Unique Identifier : AIDSLINE MED/94133081; Lasarte JJ; Sarobe P; Golvano J; Prieto I; Civeira MP; Gullon A; Sarin PS; Prieto J; Borras-Cuesta F; Departamento de Medicina Interna, Facultad de Medicina,; Universidad de Navarra, Pamplona, Spain.; Phenylalanine-containing peptides from CD4 were synthesized based on chemical similarity with active CD4(81-92)-benzylated peptides. The synthetic peptide FYIFFVEDQKEEDD blocked the binding of gp120 to CD4 and inhibited 50% human immunodeficiency virus (HIV)-induced syncytia formation at a concentration (IC50) of appr
Fetal toxicity of zidovudine (azidothymidine) in Macaca nemestrina: preliminary observations.: J Acquir Immune Defic Syndr. 1994 Feb;7(2):154-7. Unique Identifier : AIDSLINE MED/94133085; Ha JC; Nosbisch C; Conrad SH; Ruppenthal GC; Sackett GP; Abkowitz J; Unadkat JD; Regional Primate Research Center, University of Washington,; Seattle 98195.; The objective of this study was to determine the dam, fetal, and infant toxicity of zidovudine ( AZT ) administered to pigtailed macaques during pregnancy. Pregnant macaques were administered AZT (1.5 mg/kg/dose every 4 h) or water via gastric catheter
Persistent arthralgia and its association with HIV infection in Rwanda.: J Acquir Immune Defic Syndr. 1994 Feb;7(2):158-62. Unique Identifier : AIDSLINE MED/94133086; Saraux A; Taelman H; Clerinx J; Batungwanayo J; Kagame A; Kabagabo L; Bogaerts J; Van de Perre P; Le Goff P; Department of Internal Medicine, Centre Hospitalier de Kigali,; Rwanda.; A prospective study of persistent arthralgia was carried out on 331 consecutive female patients admitted to the Department of Internal Medicine of the Centre Hospitalier de Kigali in Kigali, Rwanda . The aim of this study was to determine its association with HIV-1 infection and to
HIV-1 and bleach [comment]: J Acquir Immune Defic Syndr. 1994 Feb;7(2):169-70. Unique Identifier : AIDSLINE MED/94133088; Garza BW; Drotman DP; Martin LS; McDougal JS; Bond WW; Jones TS
HIV infection among women in the Army Reserve Components.: J Acquir Immune Defic Syndr. 1994 Feb;7(2):171-6. Unique Identifier : AIDSLINE MED/94133089; Cowan DN; Brundage JF; Pomerantz RS; SRA Technologies, Inc., Alexandria, VA 22042.; There is little information regarding the extent of HIV infection among women. Since late 1985, members of the Army Reserve Components have been routinely tested for HIV, providing an opportunity to measure directly the prevalence and incidence density of infection in a military-associated population with limited mili
Prevalence of antibody to the human immunodeficiency virus among clinical laboratory specimens: findings from a survey of primary care physicians.: J Acquir Immune Defic Syndr. 1994 Feb;7(2):177-81. Unique Identifier : AIDSLINE MED/94133090; Fernando NH; Petersen LR; Conway GA; Critchley SE; Division of HIV/AIDS, Centers for Disease Control and Prevention,; Atlanta, GA 30333.; To evaluate human immunodeficiency virus type 1 (HIV-1) infection among patients of primary care physicians, we performed anonymous, unlinked HIV-1 antibody testing on leftover blood specimens submitted to 10 large commercial clinical laboratories for complete blood cell count or hematocrit determination, the most com
HIV incidence among needle exchange participants: estimates from syringe tracking and testing data.: J Acquir Immune Defic Syndr. 1994 Feb;7(2):182-9. Unique Identifier : AIDSLINE MED/94133091; Kaplan EH; Heimer R; Yale School of Organization and Management, New Haven, CT; 06520-8200.; This paper develops a statistical procedure for estimating the HIV infection rate among needle exchange clients without using any self-reported information. Instead, data are accumulated by following the distribution and return of sequentially labeled syringes and by testing a sample of returns for the presence of HIV
Sexual behavior and sexual identity in male injection drug users.: J Acquir Immune Defic Syndr. 1994 Feb;7(2):190-8. Unique Identifier : AIDSLINE MED/94133092; Lewis DK; Watters JK; University of California, Santa Cruz 95064.; Sexual behavioral data from a survey of 396 male drug injectors showed that 301 (76%) were behavioral heterosexuals, 49 (12.45%) were bisexuals, and 46 (11.6%) were homosexuals over the previous 5 years. Among those sexually active during the 6 months before the interview, bisexuals were similar to heterosexuals and h
Association of HTLV-I antibody profile of asymptomatic carriers with proviral DNA levels of peripheral blood mononuclear cells.: J Acquir Immune Defic Syndr. 1994 Feb;7(2):199-203. Unique Identifier : AIDSLINE MED/94133093; Ishihara S; Okayama A; Stuver S; Horinouchi H; Shioiri S; Murai K; Kubota T; Yamashita R; Tachibana N; Tsubouchi H; et al; Second Department of Medicine, Miyazaki Medical College, Japan.; The human T-lymphotropic virus type I (HTLV-I) antibody profile of 216 asymptomatic carriers in Miyazaki, Japan , was analyzed in conjunction with the HTLV-I proviral DNA levels in their peripheral blood mononuclear cells (PBMC) determined by the semiquantitative polymerase chain rea
Cervicovaginal virus secretion in HIV-infected women [letter; comment]: J Acquir Immune Defic Syndr. 1994 Feb;7(2):204. Unique Identifier : AIDSLINE MED/94133094; Anderson D; Johnson PM
HIV-1 inactivation by bleach [letter; comment]: J Acquir Immune Defic Syndr. 1994 Feb;7(2):204-5. Unique Identifier : AIDSLINE MED/94133095; Floyd R
HTLV-I/II seroprevalence and coinfection with other pathogens in blood donors in Buenos Aires [letter]: J Acquir Immune Defic Syndr. 1994 Feb;7(2):206-7. Unique Identifier : AIDSLINE MED/94133097; del Pino N; Martinez Peralta L; Pampuro S; Pimentel E; Libonatti O
High risk of developing toxoplasmic encephalitis in AIDS patients seropositive to Toxoplasma gondii [letter; comment]: J Acquir Immune Defic Syndr. 1994 Feb;7(2):207-8. Unique Identifier : AIDSLINE MED/94133098; Zangerle R; Allerberger F
Occupational HIV infection following a stylet injury [letter]: J Acquir Immune Defic Syndr. 1994 Feb;7(2):208-10. Unique Identifier : AIDSLINE MED/94133099; Ippolito G; Salvi A; Sebastiani M; David S; de Carli G; Puro V
Pentoxifylline and meclofenamic acid treatment reduces clinical manifestations in a murine model of AIDS.: J Pharmacol Exp Ther. 1994 Jan;268(1):10-3. Unique Identifier : AIDSLINE MED/94133106; Stadler I; Chadha KC; Nakeeb S; Toumbis C; Butsch J; Mathur N; Munschauer F; Vladutiu A; Satchidanand SK; Ambrus JL; Department of Internal Medicine, Buffalo General Hospital, State; University of New York.; C57/BL/6 mice infected with LP-BM5 MuLV virus developed an AIDS-like disease (MAIDS) with splenomegaly, leukopenia, thrombocytopenia, anemia, decreased numbers of helper/inducer and suppressor/cytotoxic T-cells and decreased production of interferon alpha. We have shown previously that HIV-associated Kaposi s sarcoma
The prevalence of oral candidiasis in HIV-infected individuals and dental attenders in Edinburgh.: J Oral Pathol Med. 1993 Oct;22(9):418-20. Unique Identifier : AIDSLINE MED/94133182; Felix DH; Wray D; Department of Oral Medicine & Oral Pathology, University of; Edinburgh, Scotland.; This study prospectively assessed the prevalence of oral candidal carriage and oral candidiasis in known HIV-seropositive individuals (n = 121) and other dental attenders in Edinburgh (n = 614). Candida species were isolated from 57.4% of dental attenders and 93.4% of HIV-seropositive subjects. Clinical evidence of or
Effects of HIV/AIDS information on attitudes toward AIDS: a cross-ethnic comparison of college students.: J Psychol. 1993 Nov;127(6):611-8. Unique Identifier : AIDSLINE MED/94133190; Goh DS; Department of Educational and Community Programs, Queens; College/CUNY, Flushing 11367-0904.; College students (N = 274) from five ethnic groups were administered an AIDS information questionnaire and the Attitudes Toward AIDS Scale (ATAS; Goh, in press) to determine the effects of AIDS information on attitudes toward AIDS. A series of chi-squares and multivariate analyses of variance indicated significant dif
Neuropsychiatric aspects of HIV-1 infection in gay men: controlled investigation of psychiatric, neuropsychological and neurological status.: J Psychosom Res. 1993 Dec;37(8):819-30. Unique Identifier : AIDSLINE MED/94133197; Riccio M; Pugh K; Jadresic D; Burgess A; Thompson C; Wilson B; Lovett E; Baldeweg T; Hawkins DA; Catalan J; Academic Department of Psychiatry, Charing Cross and Westminster; Medical School, Chelsea and Westminster Hospital, London, U.K.; The aim of this study was to determine whether HIV infection is associated with psychiatric morbidity or neuropsychological impairment in asymptomatic and early symptomatic stages of disease in gay men. The subjects were 100 gay men (68 HIV-ve, 32 HIV+ve, 6 being CDC IV). All subjects were recruited at the time of req
New guidelines encourage primary care for patients with early HIV infection [news]: JAMA. 1994 Feb 16;271(7):487. Unique Identifier : AIDSLINE MED/94133340; Marwick C
Use of antiretroviral drugs in HIV disease declines following preliminary results from Concorde trial [news]: JAMA. 1994 Feb 16;271(7):488-9. Unique Identifier : AIDSLINE MED/94133341; Cotton P
From the Agency for Health Care Policy and Research.: JAMA. 1994 Feb 16;271(7):492. Unique Identifier : AIDSLINE MED/94133344; Clinton JJ
HIV infection and risk behaviors among heterosexuals in alcohol treatment programs [see comments]: JAMA. 1994 Feb 16;271(7):515-8. Unique Identifier : AIDSLINE MED/94133362; Avins AL; Woods WJ; Lindan CP; Hudes ES; Clark W; Hulley SB; Division of General Internal Medicine, San Francisco General; Hospital, CA.; OBJECTIVE--To measure the prevalence of human immunodeficiency virus (HIV) infection and high-risk behaviors among heterosexuals in alcohol treatment. DESIGN--Cross-sectional survey. SETTING--Five public alcohol treatment centers. SUBJECTS--Consecutive sample of 888 heterosexual clients entering treatment between Octo
Rochalimaea henselae infection. A new zoonosis with the domestic cat as reservoir [see comments]: JAMA. 1994 Feb 16;271(7):531-5. Unique Identifier : AIDSLINE MED/94133365; Koehler JE; Glaser CA; Tappero JW; Department of Medicine, University of California-San Francisco; 94143-1204.; OBJECTIVE--To determine the reservoir and vector(s) for Rochalimaea henselae, a causative agent of bacillary angiomatosis (BA) and cat scratch disease, and to estimate the percentage of domestic cats with R henselae bacteremia in the Greater San Francisco Bay Region of Northe
HIV-associated immune-mediated renal disease.: Kidney Int. 1993 Dec;44(6):1327-40. Unique Identifier : AIDSLINE MED/94133542; Kimmel PL; Phillips TM; Ferreira-Centeno A; Farkas-Szallasi T; Abraham AA; Garrett CT; Department of Medicine, George Washington University Medical; Center, Washington.; Although focal glomerulosclerosis is the most common renal disease, other proliferative glomerulonephritides are encountered in HIV-infected patients. We studied four HIV-infected patients with renal insufficiency, proteinuria, and proliferative glomerulonephritis, consistent with immune-mediated disease, to investiga
[The combined immunoenzyme test: anti-HIV-1 and -2 and anti-HTLV-1 in the detection of donors with retrovirus infections]: Lijec Vjesn. 1993 May-Jun;115(5-6):142-5. Unique Identifier : AIDSLINE MED/94133863; Dobec M; Jung M; Zupancic-Salek S; Burek V; Mihaljevic I; Grgicevic D; Institut Virion, Zurich, Svicarska.; Serums of whole blood donors, plasma donors, hemophiliacs, persons with risks behavior and normal population simultaneously were tested for markers of infectious diseases, anti-HIV-1 with Plivazim and anti-HIV-1/2 and anti-HTLV-1/2 with Roche Retrovirus EIA. The positive results were confirmed by immunofluorescence as
Use of beta-lactam/beta-lactamase-inhibitor combinations as antimycobacterial agents.: Microbios. 1993;76(309):251-61. Unique Identifier : AIDSLINE MED/94133949; Prabhakaran K; Harris EB; Randhawa B; Adams LB; Williams DL; Hastings RC; Laboratory Research Branch, GWL Hansen's Disease Center,; Louisiana State University, Baton Rouge 70894-2059.; Mycobacterium tuberculosis and Mycobacterium leprae develop resistance against the drugs used to treat tuberculosis and leprosy, respectively. Now multidrug-resistant tuberculosis is spreading in many countries, especially with the emergence of AIDS. Multidrug treatment is being promoted at present to eradicate lepros
A predictive model for non-Hodgkin's lymphoma [letter; comment]: N Engl J Med. 1994 Feb 24;330(8):574; discussion 574-5. Unique Identifier : AIDSLINE MED/94134131; Myers AM; Moore GE
Treatment of presumed cerebral toxoplasmosis with azithromycin [letter]: N Engl J Med. 1994 Feb 24;330(8):575-6. Unique Identifier : AIDSLINE MED/94134134; Godofsky EW
Health care reform and the Clinton plan: nursing's perspective.: Nev Rnformation. 1993 Nov;2(4):1-3. Unique Identifier : AIDSLINE MED/94134194
Vitamin B6 and immune competence.: Nutr Rev. 1993 Aug;51(8):217-25. Unique Identifier : AIDSLINE MED/94134319; Rall LC; Meydani SN; Nutritional Immunology Laboratory, USDA Human Nutrition Research; Center on Aging, Tufts University, Boston, MA 02111.; Animal and human studies suggest that vitamin B6 deficiency affects both humoral and cell-mediated immune responses. Lymphocyte differentiation and maturation are altered by deficiency, delayed-type hypersensitivity responses are reduced, and antibody production may be indirectly impaired. Although repletion of the vi
Interactions between nutrition and infection with human immunodeficiency virus.: Nutr Rev. 1993 Aug;51(8):226-34. Unique Identifier : AIDSLINE MED/94134320; Gorbach SL; Knox TA; Roubenoff R; Department of Community Health, Tufts University School of; Medicine, Boston, MA 02111.; Nutritional status is severely compromised in persons infected with the human immunodeficiency virus (HIV). One or a combination of several disease-related factors can contribute to substantial weight loss and malnutrition, accelerating the downhill course of the disease. Efforts to prevent weight loss should include
From Task Force on Issues Related to AIDS. I don't need those anymore!: Ohio Nurses Rev. 1993 Nov-Dec;68(8):12. Unique Identifier : AIDSLINE MED/94134349; Coleman DA
Public health issues also essential to health care reform. Nursing in the community.: Ohio Nurses Rev. 1993 Nov-Dec;68(8):14. Unique Identifier : AIDSLINE MED/94134350
A masked prospective evaluation of outcome parameters for cytomegalovirus-related retinal detachment surgery in patients with acquired immune deficiency syndrome.: Ophthalmology. 1994 Jan;101(1):46-55. Unique Identifier : AIDSLINE MED/94134393; Kuppermann BD; Flores-Aguilar M; Quiceno JI; Capparelli EV; Levi L; Munguia D; Freeman WR; Department of Ophthalmology, University of California, San Diego,; La Jolla 92093-0946.; PURPOSE: The management of cytomegalovirus ( CMV )-related rhegmatogenous retinal detachments in patients with acquired immune deficiency syndrome (AIDS) has been the subject of recent attention and controversy because of the h
Transcellular activation of the HTLV promoter by human hematopoietic cells.: Oncogene. 1994 Jan;9(1):319-22. Unique Identifier : AIDSLINE MED/94134431; Baier-Bitterlich G; Rappaport J; Baier G; Looney D; Wong-Staal F; La Jolla Institute for Allergy and Immunology, California.; We examined the ability of hematopoietic cells to transactivate the HTLV promoter by a transcellular mechanism. HeLa cells containing a CAT reporter gene driven by the HTLV-2 promoter were cocultivated with hematopoietic cells of the B-(Raji), T-(HuT78, Jurkat) and monocyte/promyelocytic (THP-1, U937 and HL60) lineage
Two distinct regions form a functional activation domain of the HTLV-1 trans-activator Tax1.: Oncogene. 1994 Jan;9(1):337-40. Unique Identifier : AIDSLINE MED/94134436; Tsuchiya H; Fujii M; Tanaka Y; Tozawa H; Seiki M; Department of Molecular Virology and Oncology, Kanazawa; University, Japan.; Tax1 of human T-cell leukemia virus type 1 (HTLV-1) is an enigmatic viral transactivator that regulates expression of the viral gene and also several cellular genes normally controlled by various mitogenic signals. However, previous studies have failed to define the functional domains of Tax1 for enhancer specificitie
Condoms: effective protection against HIV?: N J Nurse. 1993 Dec;23(10):6. Unique Identifier : AIDSLINE MED/94134458; Wurmser T
Fear of OH unwarranted [letter]: Nurs Times. 1994 Jan 12-18;90(2):27. Unique Identifier : AIDSLINE MED/94134478; Lloyd P
[The killer disease 'AIDS']: Nurs J India. 1993 Jun;84(6):122-9. Unique Identifier : AIDSLINE MED/94134497; Ragho BJ
Neglected pathogens: bacterial infections in persons with human immunodeficiency virus infection. A review of the literature (2).: Pharmacotherapy. 1993 Nov-Dec;13(6):543-63. Unique Identifier : AIDSLINE MED/94134514; Fish DN; Danziger LH; Division of Pharmacy Practice, School of Pharmacy, University of; Colorado Health Sciences Center, Denver.
Pharmacotherapy of infectious complications in patients with acquired immunodeficiency syndrome.: Pharmacotherapy. 1993 Nov-Dec;13(6):626. Unique Identifier : AIDSLINE MED/94134525; Rodvold KA; Department of Pharmacy Practice, College of Pharmacy, University; of Illinois at Chicago 60612.
Mycobacterial infections.: Pharmacotherapy. 1993 Nov-Dec;13(6):634-9. Unique Identifier : AIDSLINE MED/94134527; Peloquin CA; Infectious Disease Pharmacokinetics Laboratory, National Jewish; Center for Immunology and Respiratory Medicine, Denver, Colorado; 80206.; Infection due to Mycobacterium tuberculosis continues to plague humanity. In the United States , conditions have taken a decided turn for the worse, with an increasing frequency of infection and the spread of multiple-drug-resistant strains. A number of strategies are available to impro
Pneumocystis carinii pneumonia in human immunodeficiency virus-infected infants and children.: Pharmacotherapy. 1993 Nov-Dec;13(6):640-6. Unique Identifier : AIDSLINE MED/94134528; Goodwin SD; Division of Pharmacy Practice, School of Pharmacy, University of; Colorado Health Sciences Center, Denver 80262.; Pneumocystis carinii pneumonia (PCP) is the most common opportunistic infection in adults and children infected with the human immunodeficiency virus (HIV). Without prophylaxis, half of all these children will develop PCP at sometime during their illness. The disease is associated with high mortality and a poor progno
Extracerebral toxoplasmosis in the acquired immunodeficiency syndrome (AIDS).: Pathol Res Pract. 1993 Sep;189(8):894-901. Unique Identifier : AIDSLINE MED/94134552; Hofman P; Bernard E; Michiels JF; Thyss A; Le Fichoux Y; Loubiere R; Service d'Anatomopathologie, Universite de Nice, France.; Although Toxoplasma gondii frequently causes lesions of the central nervous system in AIDS, the exact incidence of extracerebral toxoplasmosis in these immunodepressed patients remains difficult to determine. Isolation of the parasite outside the central nervous system is rarely performed ante mortem, and most diagnos
[The child and tuberculosis (editorial)]: Presse Med. 1993 Nov 6;22(34):1721-3. Unique Identifier : AIDSLINE MED/94134629; Olivier C
[Orthostatic hypotension revealing HIV infection (letter)]: Presse Med. 1993 Nov 6;22(34):1748. Unique Identifier : AIDSLINE MED/94134641; Grange C; Augey L; Durieu I; Vital Durand D; Levrat R
Phylogenetic subtypes of human T-lymphotropic virus type I and their relations to the anthropological background.: Proc Natl Acad Sci U S A. 1994 Feb 1;91(3):1124-7. Unique Identifier : AIDSLINE GENBANK/D23694; Miura T; Fukunaga T; Igarashi T; Yamashita M; Ido E; Funahashi S; Ishida T; Washio K; Ueda S; Hashimoto K; et al; Institute for Virus Research, Kyoto University, Japan.; Isolates of human T-lymphotropic virus type I (HTLV-I) were phylogenetically analyzed from native inhabitants in India and South America ( Colombia and Chile ) an
A human amphotropic retrovirus receptor is a second member of the gibbon ape leukemia virus receptor family.: Proc Natl Acad Sci U S A. 1994 Feb 1;91(3):1168-72. Unique Identifier : AIDSLINE GENBANK/L20852; van Zeijl M; Johann SV; Closs E; Cunningham J; Eddy R; Shows TB; O'Hara B; Molecular Biology Research Section, American Cyanamid Company,; Pearl River, NY 10965.; Retrovirus infection is initiated by binding of the viral envelope glycoprotein to a cell-surface receptor. The envelope proteins of type C retroviruses of mammals demonstrate similarities in structural organization and protein sequence. These similarities suggest the possibility that retroviruses from different inter
HRSA approves HIV-AIDS grants for adolescents, Native Americans [news]: Public Health Rep. 1994 Jan-Feb;109(1):149. Unique Identifier : AIDSLINE MED/94134910
WHO AIDS program director calls for revamping of medical education [news]: Public Health Rep. 1994 Jan-Feb;109(1):150. Unique Identifier : AIDSLINE MED/94134911
Guidelines for designing rapid assessment surveys of HIV seroprevalence among hospitalized patients. Centers for Disease Control and Prevention.: Public Health Rep. 1994 Jan-Feb;109(1):53-9. Unique Identifier : AIDSLINE MED/94134917; Schwartlander B; Janssen RS; Satten GA; Critchley SE; Petersen LR; Dondero TJ; Centers for Disease Control and Prevention, Atlanta, GA 30333.; The Centers for Disease Control and Prevention has developed guidelines for determining HIV seroprevalence among patients seeking medical care at acute-care hospitals. The guidelines enable hospital staff members to perform a simple, rapid, and inexpensive survey to determine seroprevalence among the patient populatio
Foster care of HIV-positive children in the United States.: Public Health Rep. 1994 Jan-Feb;109(1):60-7. Unique Identifier : AIDSLINE MED/94134918; Cohen FL; Nehring WM; College of Nursing, University of Illinois at Chicago 60612.; A national study regarding the foster care of children identified as human immunodeficiency virus-positive (HIV-positive) was conducted in 1991. A survey form was sent to the administrators of the State agency responsible for foster care in each State, the District of Columbia, and U.S. Territories for a total sample
Effects of thymus humoral factor gamma-2 (THF gamma 2) on lymphohaematopoietic progenitor cells: an in vitro study.: Res Immunol. 1993 Jul-Sep;144(6-7):395-406. Unique Identifier : AIDSLINE MED/94134981; Calenda V; Silvy F; Chermann JC; INSERM Unite 322, Parc Scientifique et Technologique de Luminy,; Marseille, France.; Thymus humoral factor gamma-2 (THF gamma 2), an immunomodulatory factor, was previously shown to exert a regulatory effect upon human haematopoietic development. In the present study, we were primarily interested in determining whether THF gamma 2 has an immunorestorative effect after HIV infection. Although no inhibi
[Hemiballismus disclosing cerebral toxoplasmosis and acquired immunodeficiency syndrome]: Rev Neurol (Paris). 1993;149(6-7):421-3. Unique Identifier : AIDSLINE MED/94135115; Awada A; Dept. of Neurology, King Faisal University, Dammam, Arabie; Saoudite.; A 33-year-old Saudi woman presented with right hemiballismus of recent onset. Brain CT showed a left thalamo-subthalamic lesion which was thought initially to be a metastasis or a tuberculoma. The presence of severe subacute diarrhea, multiple lymphadenopathies and lymphopenia suggested an acquired immunodeficiency sy
[Meningoradiculitis disclosing T-lymphocyte leukemia in HTLV-1 infection]: Rev Neurol (Paris). 1993;149(6-7):428-31. Unique Identifier : AIDSLINE MED/94135118; Visy JM; Vassel P; Chaine P; Woimant F; Dumas JL; Lhote F; Mainguene C; Haguenau M; Service de Neurologie, Hopital Lariboisiere, Paris.; A case of HILV1-associated adult T cell leukaemia/lymphoma (ATLL) in a 21-year olf African woman is reported. The patient presented with lymphomatous meningoradiculopathy. The usual clinical features of ATLL were absent. Lumbar MRI showed a pial enhancement by DTPA-gadolinium of the conus medullaris which extended to
HIV vaccines--a report from the front.: RN. 1994 Jan;57(1):36-40. Unique Identifier : AIDSLINE MED/94135122; Zurlinden J; Verheggen R
[Lymphomas in immunocompromised hosts]: Rev Prat. 1993 Sep 1;43(13):1661-4. Unique Identifier : AIDSLINE MED/94135136; Berger F; Delecluse HJ; Laboratoire d'anatomie pathologique, hopital Edouard-Herriot,; Lyon.; Congenital and acquired states of immunodeficiency are associated with an increased incidence of ill-defined lymphoproliferations. These are mainly B-cell, often extranodal, lymphoproliferations commonly associated with EBV. Their incidence is increasing with the rapid development of organ transplantation and spreadin
New tool for predicting AIDS onset? [news]: Science. 1994 Feb 4;263(5147):606. Unique Identifier : AIDSLINE MED/94135222
Alloimmunization to prevent AIDS? [letter; comment]: Science. 1994 Feb 11;263(5148):737-8. Unique Identifier : AIDSLINE MED/94135241; Kiprov DD; Sheppard HW; Hanson CV
AIDS institute in turmoil [news]: Science. 1994 Feb 11;263(5148):743. Unique Identifier : AIDSLINE MED/94135242; Stone R
New advances in vaccine delivery systems.: Semin Hematol. 1993 Oct;30(4 Suppl 4):16-24; discussion 25. Unique Identifier : AIDSLINE MED/94135267; Eldridge JH; Staas JK; Chen D; Marx PA; Tice TR; Gilley RM; Department of Medicine, University of Alabama at Birmingham.; Successful application of the next generation of vaccines will require that protection be induced with a minimal number of administrations, and that a practical approach to inducing immunity at mucosal surfaces be developed. For these reasons, vaccine-containing microspheres were formulated from the biodegradable and
International migration and control of communicable diseases.: Soc Sci Med. 1993 Dec;37(12):1489-99. Unique Identifier : AIDSLINE MED/94135297; Gellert GA; Arizona Department of Health Services, Phoenix 85015.; The epidemiology and policy implications of communicable disease (CD) transmission associated with international migration have received little systematic study. This is a review of clinical and epidemiological reports in search of strategies to assess and manage the impact of international migration on the transmissi
Evaluation of AIDS prevention among homosexual and bisexual men in Switzerland.: Soc Sci Med. 1993 Dec;37(12):1539-44. Unique Identifier : AIDSLINE MED/94135302; Dubois-Arber F; Masur JB; Hausser D; Zimmermann E; Paccaud F; University Institute for Social and Preventive Medicine,; Lausanne, Switzerland.; Attitudinal and behavioural change among gay men in Switzerland was measured between 1987 and 1990 to evaluate the effectiveness of AIDS prevention activities. The methodology used included a self-administered questionnaire published in Swiss gay magazines and distributed by g
Computer-based education for evaluation of oral lesions.: Spec Care Dentist. 1993 Jul-Aug;13(4):146-50. Unique Identifier : AIDSLINE MED/94135514; Brody HA; Lucaccini LF; Kamp M; Advanced Education in General Dentistry Program, University of; California at San Francisco School of Dentistry.; This paper describes the development of a computer-based educational module for dental students, dental hygiene students, and dental practitioners and instructs the user in screening activities for oral lesions associated with cancer or the HIV virus.
[Biological diagnosis of HIV infections in children]: Soins Gynecol Obstet Pueric Pediatr. 1993 Jun-Jul;(145-6):13-6. Unique Identifier : AIDSLINE MED/94135553; Cadin P
[Jean-Baptiste]: Soins Gynecol Obstet Pueric Pediatr. 1993 Jun-Jul;(145-6):21-5. Unique Identifier : AIDSLINE MED/94135555; Noblet C; Boyer S; Martinais K; Vigouroux S; Bazeille C
[Ronald]: Soins Gynecol Obstet Pueric Pediatr. 1993 Jun-Jul;(145-6):26-31. Unique Identifier : AIDSLINE MED/94135556; Bricaud S; Cousin S; Barlaud Y; Delolme C
[AIDS and hygiene. Nursing care teams]: Soins Gynecol Obstet Pueric Pediatr. 1993 Jun-Jul;(145-6):35-6. Unique Identifier : AIDSLINE MED/94135558; Mazue MC
[Psychological approach to AIDS]: Soins Gynecol Obstet Pueric Pediatr. 1993 Jun-Jul;(145-6):37-40. Unique Identifier : AIDSLINE MED/94135559; Rivet-Larrue B
[The pediatric and rehabilitation center at Bullion, a place to stay for children]: Soins Gynecol Obstet Pueric Pediatr. 1993 Jun-Jul;(145-6):4-6. Unique Identifier : AIDSLINE MED/94135560; Gouriou Y
[History of 2 children under family placement]: Soins Gynecol Obstet Pueric Pediatr. 1993 Jun-Jul;(145-6):45-6. Unique Identifier : AIDSLINE MED/94135562; Normand C
[Education and courses of study for children with HIV infection in long-term care]: Soins Gynecol Obstet Pueric Pediatr. 1993 Jun-Jul;(145-6):47-53. Unique Identifier : AIDSLINE MED/94135563; Trevelot JC
Texas AIDS facts [news]: Tex Nurs. 1994 Jan;68(1):9. Unique Identifier : AIDSLINE MED/94135635
HIV in the lung: guilty or not guilty? [editorial]: Thorax. 1993 Dec;48(12):1191-5. Unique Identifier : AIDSLINE MED/94135637; Mayaud CM; Cadranel J
Relation of HIV-I in bronchoalveolar lavage cells to abnormalities of lung function and to the presence of Pneumocystis pneumonia in HIV-I seropositive patients.: Thorax. 1993 Dec;48(12):1222-6. Unique Identifier : AIDSLINE MED/94135643; Clarke JR; Taylor IK; Fleming J; Williamson JD; Mitchell DM; Department of Medical Microbiology, St Mary's Hospital Medical; School, London.; BACKGROUND--HIV is present in bronchoalveolar lavage cells of some but not all HIV seropositive patients. Abnormalities of lung function have been described in such patients in the absence of clinically overt pneumonia or other respiratory infections. It is possible that the presence of HIV in alveolar macrophages cou
Chlamydia pneumoniae seroprevalence in immunocompetent and immunocompromised populations in Milan.: Thorax. 1993 Dec;48(12):1261-3. Unique Identifier : AIDSLINE MED/94135651; Blasi F; Cosentini R; Schoeller MC; Lupo A; Allegra L; Institute of Respiratory Diseases, University of Milan, Italy.; BACKGROUND--Chlamydia pneumoniae is drawing increasing attention as an agent of respiratory tract infection. Specific antibody prevalence in western countries is low in preschool children and reaches more than 50% in adults. However, little is known about the prevalence of this infection in immunocompromised subjects
[Muscular weakness in a young woman]: Union Med Can. 1993 Nov-Dec;122(6):404-5, 454-5. Unique Identifier : AIDSLINE MED/94135820; Cormier G; Masson H; Turgeon PP; Beauregard H; Notre Dame hospital, Quebec, Canada.
[The isolation and characteristics of monoclonal antibodies to recombinant proteins of HIV-1 and HIV-2--the env and gag gene products]: Vopr Virusol. 1993 Nov-Dec;38(6):253-5. Unique Identifier : AIDSLINE MED/94135954; Pugach AV; Zverev VV; Pille ER; Shukhmina NR; Mel'nikova NL; Nosik DN; Maliushova VV; Andzhaparidze OG; Ten hybridomas secreting monoclonal antibodies (Mab) against recombinant HIV-1 and HIV-2 antigens were produced (3 Mab anti-gag protein, 2 anti-env1, and 5 anti-env2). In the immunoblotting assay all the anti-gag Mabs reacted with HIV capsid protein p24, whereas one of them reacted also with p55 protein and with 7 oth
[The risk factors for the transmission of HIV infection among intravenous narcotic users in Russia]: Vopr Virusol. 1993 Nov-Dec;38(6):258-61. Unique Identifier : AIDSLINE MED/94135956; Savchenko IG; Pokrovskii VV; Briun EA; Blood sera (316,281 specimens) from registered drug and toxic substance addicts were examined revealing no subjects seropositive to HIV. A special epidemiological questionnaire was developed and used for questioning of 86 drug addicts using drugs prepared domestically by the intravenous route. The group included 56 me
Primary in vitro sensitization of human T-helper lymphocytes by peptides derived from the V3 loop of human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein.: Vaccine. 1994 Jan;12(1):46-55. Unique Identifier : AIDSLINE MED/94136014; Billaud JN; Yagello M; Gluckman JC; CNRS URA 1463, CERVI, Hopital de la Pitie-Salpetriere, Paris,; France.; To generate CD4+ T-helper cell lines, lymphocytes from HIV-seronegative subjects were primed in vitro with peptides derived from the V3 loop of HIV-1 gp120. Antigen-specific reactivity was inhibited by an anti-DR monoclonal antibody, indicating HLA-class II dependency, but peptides could be recognized in different HLA
Presence of papova-like viral particles in cerebrospinal fluid of AIDS patients with progressive multifocal leukoencephalopathy. An additional test for in vivo diagnosis.: Acta Neurol (Napoli). 1993 Oct;15(5):328-32. Unique Identifier : AIDSLINE MED/94136187; Orefice G; Campanella G; Cicciarello S; Chirianni A; Borgia G; Rubino S; Mainolfi M; Coppola M; Piazza M; Second Department of Neurology, Medical School, Federico II; University, Naples, Italy.; An in vivo diagnosis of progressive multifocal leukoencephalopathy (PML), a neurological opportunistic viral infection in AIDS patients, can be made only by brain biopsy. In order to identify viral particles, we examined the cerebrospinal fluid (CSF) of 15 AIDS patients with focal neurological signs by electron micros
Acute meningitis from Cryptococcus neoformans (Filobasidiella neoformans) in a patient suffering from AIDS. Report of a clinical case with a favourable outcome.: Acta Neurol (Napoli). 1993 Oct;15(5):341-7. Unique Identifier : AIDSLINE MED/94136189; Loschiavo F; Ventura-Spagnolo T; Sessa E; Bramanti P; Chair of Neurophysiopathology, University of Messina.; The Authors describe a case of acute meningitis from Cryptococcus neoformans, with the finding of the fungus in the cerebrospinal fluid and in culture in a young subject with AIDS. The case had a favourable outcome after fluconazole treatment.
Role of viruses in the etiopathogenesis of multiple sclerosis.: Acta Neurol (Napoli). 1993 Oct;15(5):363-81. Unique Identifier : AIDSLINE MED/94136192; Sarchielli P; Trequattrini A; Usai F; Murasecco D; Gallai V; Department of Nervous and Mental Diseases, University of Perugia,; Italy.; Epidemiological studies performed to identify the possible cause of Multiple Sclerosis (MS) suggest that an environmental agent could be involved in its etiopathogenesis. For a long time it has been hypothesized that this agent was a virus, but until now no virus specific to MS has been consistently identified. Animal
AAFP establishes an HIV 'warm line' to assist physicians [news]: Am Fam Physician. 1994 Feb 1;49(2):307. Unique Identifier : AIDSLINE MED/94136387
Mucocutaneous manifestations of chancroid, lymphogranuloma venereum and granuloma inguinale.: Am Fam Physician. 1994 Feb 1;49(2):415-8, 423-5. Unique Identifier : AIDSLINE MED/94136399; Goens JL; Schwartz RA; De Wolf K; Free University of Brussels, Belgium.; The sexually transmitted diseases chancroid, lymphogranuloma venereum and granuloma inguinale should be familiar to physicians who care for patients at risk. The mucocutaneous manifestations of these three diseases must be distinguished from the lesions of other venereal diseases, such as primary syphilis and
Incidence of HIV infection [news]: Am Fam Physician. 1994 Feb 1;49(2):508. Unique Identifier : AIDSLINE MED/94136404
Pharmacists' role in preventing and treating HIV infection.: Am Pharm. 1993 Dec;NS33(12):38-44. Unique Identifier : AIDSLINE MED/94136407; Noormohamed SE; Ferguson K; College of Pharmacy, University of Iowa, Iowa City.
Colon adenocarcinoma in HIV infection: a case report and review.: Am J Gastroenterol. 1994 Feb;89(2):254-6. Unique Identifier : AIDSLINE MED/94136452; Klugman AD; Schaffner J; Department of Internal Medicine, Rush-Presbyterian St. Luke's; Medical Center, Chicago, Illinois.; Gastrointestinal adenocarcinoma is a disease seen uncommonly in HIV-infected patients. The present case is that of a 25-yr-old black male who was HIV positive and developed right-sided colon adenocarcinoma. This case is an example of the growing number of adenocarcinomas of the gastrointestinal tract being reported in
Leishmania esophagitis in an AIDS patient: an unusual form of visceral leishmaniasis.: Am J Gastroenterol. 1994 Feb;89(2):273-5. Unique Identifier : AIDSLINE MED/94136457; Villanueva JL; Torre-Cisneros J; Jurado R; Villar A; Montero M; Lopez F; Sanchez-Guijo P; Kindelan JM; Infectious Diseases Unit, Hospital Universitario Reina Sofia,; Cordoba, Spain.; Esophageal disease is a common cause of morbidity in patients infected by human immunodeficiency virus (HIV). Although gastrointestinal involvement of leishmaniasis has been previously reported, we believed that we describe the first case of leishmania esophagitis. Clinical data and the endoscopic and histologic hallm
Absence of prolonged immunosilent infection with human immunodeficiency virus in individuals with high-risk behaviors.: Am J Med. 1994 Jan;96(1):42-8. Unique Identifier : AIDSLINE MED/94136505; Coutlee F; Olivier C; Cassol S; Voyer H; Kessous-Elbaz A; Saint-Antoine P; He Y; Fauvel M; Centre de Recherche, Hopital Notre-Dame, Montreal, PQ, Canada.; PURPOSE: The presence in some individuals of a prolonged phase of infection with human immunodeficiency virus type 1 (HIV-1) before seroconversion remains controversial. This study was undertaken to determine with a sensitive in vitro amplification technique, the polymerase chain reaction (PCR), whether seronegative i
Clostridium difficile colitis associated with trimethoprim-sulfamethoxazole given as prophylaxis for Pneumocystis carinii pneumonia.: Am J Med. 1994 Jan;96(1):94-5. Unique Identifier : AIDSLINE MED/94136513; Gordin F; Gibert C; Schmidt ME; Veterans Affairs Medical Center, Washington, D.C.
Pyrimethamine alone as long-term suppressive therapy in cerebral toxoplasmosis.: Am J Med. 1994 Jan;96(1):95-6. Unique Identifier : AIDSLINE MED/94136514; Murphy K; Groarke M; O'Shaughnessy E; Buckley A; Mitchell T; Cork Regional Hospital, Wilton, Ireland.
Support urged for needle exchange programs [news]: Am J Nurs. 1993 Dec;93(12):12. Unique Identifier : AIDSLINE MED/94136516
Antibiotic gets FDA nod for MAC treatment [news]: Am J Nurs. 1994 Feb;94(2):13. Unique Identifier : AIDSLINE MED/94136532
Understanding prophylactic therapy for HIV infections [see comments]: Am J Nurs. 1994 Feb;94(2):36-41; quiz 42. Unique Identifier : AIDSLINE MED/94136542; Anastasi JK; Rivera J; AIDS Program, Columbia University School of Nursing, New York.
HIV and bloodborne infections in emergency medicine. American College of Emergency Physicians.: Ann Emerg Med. 1994 Feb;23(2):401-2. Unique Identifier : AIDSLINE MED/94136815
Understanding the primary care link to treating substance abuse.: Am Nurse. 1994 Jan;26(1):12. Unique Identifier : AIDSLINE MED/94136819; Cassetta RA
Scientific session emphasizes impact of nursing research.: Am Nurse. 1994 Jan;26(1):7. Unique Identifier : AIDSLINE MED/94136824; Mikulencak M
Special problems in treating tuberculosis [letter; comment]: Ann Intern Med. 1994 Mar 1;120(5):440-1; discussion 441. Unique Identifier : AIDSLINE MED/94136860; Salomon N; Perlman DC; Goldstein S
Profound deficiency in normal circulating T cells in erythrodermic cutaneous T-cell lymphoma.: Arch Dermatol. 1994 Feb;130(2):198-203. Unique Identifier : AIDSLINE MED/94137045; Heald P; Yan SL; Edelson R; Department of Dermatology, Yale University School of Medicine,; New Haven, Conn.; BACKGROUND AND DESIGN: To accurately assess tumor burden in cutaneous T-cell lymphoma as well as to determine the number of residual normal circulating T cells, it is necessary to accurately distinguish malignant cells. Because cutaneous T-cell lymphoma cells regularly display many normal phenotypic markers of T cells
Dressings and surgical aids.: Aust Fam Physician. 1993 Nov;22(11):2046-7. Unique Identifier : AIDSLINE MED/94137158; Kelly BR
Antiviral activity of 2',3'-dideoxy-beta-L-5-fluorocytidine (beta-L-FddC) and 2',3'-dideoxy-beta-L-cytidine (beta-L-ddC) against hepatitis B virus and human immunodeficiency virus type 1 in vitro.: Biochem Pharmacol. 1994 Jan 20;47(2):171-4. Unique Identifier : AIDSLINE MED/94137264; Lin TS; Luo MZ; Liu MC; Pai SB; Dutschman GE; Cheng YC; Department of Pharmacology and the Comprehensive Cancer Center,; Yale University School of Medicine, New Haven, CT 06510.; 2 ,3 -Dideoxy-beta-L-5-fluorocytidine (beta-L-FddC) and 2 ,3 -dideoxy-beta-L-cytidine (beta-L-ddC), two nucleosides with unnatural L-configuration, have been synthesized and found to have potent antiviral activity against hepatitis B virus (HBV) and human immunodeficiency virus type 1 (HIV-1) in vitro with very little
Changes in knowledge of HIV/AIDS, sexual behaviour and practice among STD patients in Greenland 1990-1992. Monitoring the Stop-AIDS campaign in Greenland.: Arctic Med Res. 1993 Oct;52(4):145-52. Unique Identifier : AIDSLINE MED/94137301; Moi H; Froms E; Olsen J; Misfeldt J; Melbye M; Queen Ingrids Hospital, Nuuk, Greenland.; Due to a high incidence of STDs Greenland is considered to be a high risk area for an AIDS epidemic, and a close monitoring system has been set up to monitor the spread of HIV and changes in knowledge and sexual norms. This is the s
[AIDS as non-suspected cause of chronic diarrhea and malabsorption]: Rev Esp Enferm Dig. 1993 Nov;84(5):336-8. Unique Identifier : AIDSLINE MED/94137518; Sanchez E; Santa JM; Gutierrez JA; Diaz-Lobon JM; Perez-Piqueras J; Madrona C; Hospital del Aire, Madrid.; We report a case of chronic diarrhoea resulting in malabsorption syndrome in a patient with AIDS. Diarrhoea started two years before AIDS was diagnosed. The absence of risk factors may have delayed the diagnosis.
Global programme on AIDS. AIDS surveillance in the WHO Western Pacific Region.: Wkly Epidemiol Rec. 1993 Dec 10;68(50):371-5. Unique Identifier : AIDSLINE MED/94137567
Cutaneous manifestations of mycobacterial infection in patients with AIDS.: Br J Dermatol. 1994 Jan;130(1):111-4. Unique Identifier : AIDSLINE MED/94137572; Inwald D; Nelson M; Cramp M; Francis N; Gazzard B; HIV/GUM Unit, Chelsea and Westminister Hospital, London, U.K.
Cutaneous sarcoid-like granulomas in primary immunodeficiency disorders.: Br J Dermatol. 1994 Jan;130(1):118-20. Unique Identifier : AIDSLINE MED/94137574; Levine TS; Price AB; Boyle S; Webster AD; Department of Cellular Pathology, Northwick Park Hospital and; Clinical Research Centre, Harrow, Middlesex, U.K.; We report the occurrence of cutaneous sarcoid-like granulomas in one patient with common variable immunodeficiency and another with thymoma and hypogammaglobulinaemia . To our knowledge, this is the first time that such skin lesions have been described in patients with primary immunodeficiency. These granulomas may b
Liposomal daunorubicin in advanced Kaposi's sarcoma: a phase II study.: Clin Oncol (R Coll Radiol). 1993;5(6):367-71. Unique Identifier : AIDSLINE MED/94137635; Money-Kyrle JF; Bates F; Ready J; Gazzard BG; Phillips RH; Boag FC; Kobler Centre, St Stephen's Clinic, London, UK.; We report a non-randomized Phase II clinical trial to assess the efficacy and safety of liposomal daunorubicin (DaunoXome) in the treatment of AIDS related Kaposi s sarcoma. Eleven homosexual men with advanced Kaposi s sarcoma were entered in the trial. Changes in size,
Liposomal doxorubicin for treatment of AIDS-related Kaposi's sarcoma.: Clin Oncol (R Coll Radiol). 1993;5(6):372-4. Unique Identifier : AIDSLINE MED/94137636; Simpson JK; Miller RF; Spittle MF; Meyerstein Institute of Clinical Oncology, Middlesex Hospital,; London, UK.; Sixteen patients with advanced AIDS-related Kaposi s sarcoma received liposomal doxorubicin (Doxil, Liposome Technology, Menlo Park, California) at 20 mg/m2 every 2 or 3 weeks in an open label study, and were evaluated for efficacy and toxicity. Eleven patients achieved a partial rem
Five case reports of high grade non-Hodgkin's lymphoma in human immunodeficiency virus-1 negative homosexual men.: Clin Oncol (R Coll Radiol). 1993;5(6):375-7. Unique Identifier : AIDSLINE MED/94137637; Simpson JK; Mills W; Spittle MF; Meyerstein Institute of Clinical Oncology, Middlesex Hospital,; London, UK.; High grade non-Hodgkin s lymphoma accounts for only 5%-10% of all non-Hodgkin s lymphoma. Infection with the human immunodeficiency virus increases the risk of developing high grade, usually B-cell, lymphoma, which has been noted to occur more commonly in homosexual men. These lympf
Adnexal findings in AIDS.: Ophthal Plast Reconstr Surg. 1993 Dec;9(4):273-9. Unique Identifier : AIDSLINE MED/94137653; Mansour AM; Department of Ophthalmology, University of Texas Medical Branch,; Galveston.; We reviewed the adnexal and orbital findings in a large population with HIV infection followed in one medical center. Around 6% of the series had positive periocular findings. In 1% of the series, the periocular findings were the first manifestation of HIV infection or AIDS. We present the first case of basal cell carf
Perinatal findings in children born to HIV-infected mothers. The European Collaborative Study.: Br J Obstet Gynaecol. 1994 Feb;101(2):136-41. Unique Identifier : AIDSLINE MED/94137666; OBJECTIVE: To explore in children born to HIV-infected women, the association between a child s HIV infection status and birthweight, gestational age, congenital abnormalities and other perinatal findings. DESIGN: A prospective study of children born to women known to be HIV-infected at or before the time of delivery f
Membrane properties of antiviral phospholipids containing heteroatoms in the acyl chains.: Biochemistry. 1994 Feb 1;33(4):960-72. Unique Identifier : AIDSLINE MED/94137726; Qiu X; Pidgeon C; Department of Medicinal Chemistry and Pharmacognosy, School of; Pharmacy, Purdue University, West Lafayette, Indiana 47907.; Phospholipids containing heteroatoms in the lipid acyl chains, e.g., 1,2-bis(12-methoxydodecanoyl)-sn-3-phosphocholine (L-AC2), exhibit potent anti-HIV activity [Pidgeon, C., Markovich, R. J., Liu, M. D., Holzer, T., Novak, R., & Keyer, K. (1993) J. Biol. Chem. 268, 7773-7778]. AC2 is a synthetic chemical analog of
[Bacteremia caused by Mycobacterium tuberculosis and/or Mycobacterium avium detected by the non-radiometric Bactec system]: Enferm Infecc Microbiol Clin. 1993 Nov;11(9):494-6. Unique Identifier : AIDSLINE MED/94137852; Planes AM; Gasser I; Gonzalez T; Ramirez A; Arcalis L; Servicio de Microbiologia, Ciutat Universitaria de la Vall; d'Hebron, Barcelona.; BACKGROUND: To assess the utility of Bactec non-radiometric system in detecting disseminated mycobacteremia. METHODS: Blood cultures are processed using the Bactec NR 660/HPS system. Incubation of the NR6A vials, from HIV infected patients, is prolonged for 6 weeks and read once a week. After the 14th day of incubatio
[Polyadenopathies in an HIV-positive patient with multiple tattoos]: Enferm Infecc Microbiol Clin. 1993 Nov;11(9):509-10. Unique Identifier : AIDSLINE MED/94137856; Rodriguez R; Miranda C; Martinez M; Naval G; de Toro Santos JM; Unidad de Enfermedades Infecciosas, Medicina Interna, Anatomia; Patologica y Cirugia, Hospital Santa Maria Madre, Orense.
[Acute brucellosis and HIV infection: a new particularity (letter; comment)]: Enferm Infecc Microbiol Clin. 1993 Nov;11(9):511-2. Unique Identifier : AIDSLINE MED/94137858; Valladares M; Viciana P; Martin A; del Nozal M
[Idiopathic esophageal ulcer cured with corticosteroids in a patient with HIV infection (letter)]: Enferm Infecc Microbiol Clin. 1993 Nov;11(9):517-8. Unique Identifier : AIDSLINE MED/94137862; Espinasa Parra FJ; Garcia Perez B; Martinez Madrid O; Perez Pagan C
Preventing the sexual spread of HIV infection--what have we learned? [editorial]: Int J STD AIDS. 1993 Nov-Dec;4(6):311-6. Unique Identifier : AIDSLINE MED/94137863; Thornton S; Catalan J
Haemophilus ducreyi [editorial]: Int J STD AIDS. 1993 Nov-Dec;4(6):317-21. Unique Identifier : AIDSLINE MED/94137864; Jonasson JA; Genital ulcer disease as a risk factor for HIV transmission has become apparent in the fight against AIDS. In poor communities in developing countries with people living under low hygienic conditions chancroid is often reported to be the most common form of genital ulcer. It is caused by Haemophilus ducreyi; a fastidi
Cytomegalovirus retinitis: diagnosis and treatment [editorial]: Int J STD AIDS. 1993 Nov-Dec;4(6):322-5. Unique Identifier : AIDSLINE MED/94137865; Maclean H; Dhillon B; Cytomegalovirus ( CMV ) is a non-pathogenic organism in the immunocompetent, but is a major cause of morbidity and mortality amongst patients with AIDS, and the retina is the commonest site of infection. If left untreated, patients with CMVR will develop disease i
Desire for unprotected intercourse preceding its occurrence: the case of young gay men with an anonymous partner.: Int J STD AIDS. 1993 Nov-Dec;4(6):326-9. Unique Identifier : AIDSLINE MED/94137866; Gold RS; Skinner MJ; Faculty of Education, Deakin University (Geelong Campus),; Victoria, Australia.; One sample of young gay men (n = 219) and 3 samples of older gay men (n = 219, n = 207, and n = 88) recalled a sexual encounter in which they had engaged in unprotected anal intercourse. Throughout the evening of the encounter, desire specifically for unprotected intercourse had generally been less common the more dis
PPNG at St Thomas' Hospital--a changing provenance.: Int J STD AIDS. 1993 Nov-Dec;4(6):330-2. Unique Identifier : AIDSLINE MED/94137867; Sherrard J; Barlow D; Department of Genitourinary Medicine, St Thomas' Hospital,; London, UK.; Between 1986 and 1992, 15% of all cases of penicillinase-producing Neisseria gonorrhoeae (PPNG) notified in the UK were seen at our central London clinic. During this time the geographical provenance of PPNG has changed. Africa and SE Asia have been supplanted by the Caribbean as the predominant source, with 21.4% of
The reliability and validity of a symptom checklist for use in HIV infection: a preliminary analysis.: Int J STD AIDS. 1993 Nov-Dec;4(6):333-8. Unique Identifier : AIDSLINE MED/94137868; Burgess AP; Irving G; Riccio M; Department of Psychological Medicine, Charing Cross & Westminster; Medical School, London, UK.; The aim of the study was to determine the reliability and validity of a self-report symptom checklist designed for use in HIV infection. One hundred and seventy-one gay men completed a 28-item symptom checklist which produces 3 dimensions: physical, cognitive and psychological. The validity of each dimension was exami
Cytomegalovirus retinitis and AIDS in Edinburgh.: Int J STD AIDS. 1993 Nov-Dec;4(6):339-41. Unique Identifier : AIDSLINE MED/94137869; Dhillon B; Maclean H; Eddyshaw D; Cheong I; Flegg P; Brettle R; Princess Alexandra Eye Pavilion, Edinburgh, UK.; The medical records, retinal drawings and fundus photographs of all patients with cytomegalovirus retinitis (CMVR) and AIDS in Edinburgh between 1986-1992 were reviewed to determine the efficacy of treatment in preserving vision. Ophthalmoscopic features of CMVR were observed in 32
Human immunodeficiency virus infection of early passage cervical epithelial cultures.: Int J STD AIDS. 1993 Nov-Dec;4(6):342-5. Unique Identifier : AIDSLINE MED/94137870; Patrick SL; Wright TC; Fox HE; Ginsberg HS; Department of Obstetrics and Gynecology, Columbia University,; Columbia Presbyterian Medical Center, New York, NY 10032.; Women are infected with HIV in increasing numbers; the predominant mode of spread is through heterosexual transmission. Little is known regarding the mechanism of HIV transit through the female genital tract. We investigated whether early passage cervical epithelial cells could be directly infected with HIV-1LAI. Viru
Vaginal cytomegalovirus infection in a woman with AIDS.: Int J STD AIDS. 1993 Nov-Dec;4(6):346-7. Unique Identifier : AIDSLINE MED/94137871; Shah PN; Barton SE; Chelsea and Westminster Hospital, London, UK.
Heterosexual transmission of HIV: a global view a decade later.: Int J STD AIDS. 1993 Nov-Dec;4(6):353-6. Unique Identifier : AIDSLINE MED/94137873; Mann JM; Harvard School of Public Health, Boston, MA 02115.
Emerging patterns of heterosexual HIV infection and transmission. Closing statement.: Int J STD AIDS. 1993 Nov-Dec;4(6):357-62. Unique Identifier : AIDSLINE MED/94137874; Krause RM; Fogarty International Center for Advanced Study in the Health; Sciences, National Institutes of Health, Bethesda, MD 20892.
Emerging patterns of heterosexual HIV infection and transmission. Closing remarks.: Int J STD AIDS. 1993 Nov-Dec;4(6):363-4. Unique Identifier : AIDSLINE MED/94137875; Adler MW; Academic Department of Genito-urinary Medicine, University; College Medical School, London, UK.
Comparison of a new orally potent tripeptide HIV-1 protease inhibitor (anti-AIDS drug) based on pharmacokinetic characteristics in rats after intravenous and intraduodenal administrations.: Biopharm Drug Dispos. 1993 Nov;14(8):697-707. Unique Identifier : AIDSLINE MED/94137931; Kiriyama A; Mimoto T; Kisanuki S; Kiso Y; Takada K; Department of Pharmaceutics and Pharmacokinetics, Kyoto; Pharmaceutical University, Japan.; Recently, a series of KNI compounds such as KNI-227 and KNI-272 has been synthesized and shows potent and selective HIV-1 protease inhibitory activity in vitro. In this study, we developed an HPLC assay system for KNI-227 and KNI-272 in rat plasma and examined the pharmacokinetic characteristics in rats after both int
Treatment of cryptosporidial diarrhea in an AIDS patient with paromomycin.: Ann Pharmacother. 1993 Dec;27(12):1460-2. Unique Identifier : AIDSLINE MED/94138128; Danziger LH; Kanyok TP; Novak RM; Department of Pharmacy Practice, Colleges of Pharmacy and; Medicine, University of Illinois at Chicago 60612.; OBJECTIVE: To report a case of diarrhea caused by Cryptosporidium in an AIDS patients which was successfully treated with paromomycin. CASE SUMMARY: An AIDS patient with a 12-month history of cryptosporidial diarrhea unresponsive to other treatment measures was treated with paromomycin 500 mg q6h for 14 days. Before i
Atovaquone: a review.: Ann Pharmacother. 1993 Dec;27(12):1488-94. Unique Identifier : AIDSLINE MED/94138137; Haile LG; Flaherty JF; Division of Clinical Pharmacy, School of Pharmacy, University of; California, San Francisco 94143.; OBJECTIVE: To review the chemistry, pharmacology, pharmacokinetics, clinical efficacy, and safety of atovaquone. DATA IDENTIFICATION: An English-language literature search using MEDLINE (1984-1993), programs and abstracts of the 30th, 31st, and 32nd Interscience Conferences on Antimicrobial Agents and Chemotherapy, pr
Pharmacotherapy of disseminated histoplasmosis in patients with AIDS.: Ann Pharmacother. 1993 Dec;27(12):1510-8. Unique Identifier : AIDSLINE MED/94138140; Drew RH; Division of Infectious Diseases, Duke University Medical Center,; Durham, NC 27710.; OBJECTIVE: To review the pharmacotherapy of disseminated histoplasmosis (DH) in patients with AIDS. The article provides an overview of the pathophysiology, epidemiology, clinical presentation and diagnosis of this disease. Clinical trials reporting intervention with antifungal therapy are reviewed, with an emphasis o
An epidemiological model for HIV/AIDS with proportional recruitment.: Math Biosci. 1993 Dec;118(2):181-95. Unique Identifier : AIDSLINE MED/94138193; Lin X; Hethcote HW; van den Driessche P; Department of Applied Mathematics, University of Waterloo,; Ontario, Canada.; A model for HIV transmission is formulated for a homosexual population of varying size, with recruitment into the susceptible class proportional to the active population size and with stages of progression to AIDS. Analysis of this model includes identifying the threshold that determines whether the disease dies out o
Characteristic features of HIV/AIDS in the Czech Republic.: Cent Eur J Public Health. 1993 Jun;1(1):7-9. Unique Identifier : AIDSLINE MED/94138271; Bruckova M; Jedlicka J; Petkov V; Tomasek L; Vojtechovsky K; National Institute of Public Health, Prague, Czech Republic.; First laboratory proved HIV infections in the Czech Republic were diagnosed in a homosexual couple in autumn of 1985. Total number of detected HIV+ cases reached 143 persons by the end of 1992 (132 men and 11 women), of that 31 cases were classified as fully blown AIDS (21 a
HIV infection and AIDS among drug injectors at Rio de Janeiro: perspectives and unanswered questions.: Bull Narc. 1993;45(1):107-15. Unique Identifier : AIDSLINE MED/94138311; Lima ES; Bastos FI; Telles PR; Friedman SR; Nucleo de Estudos e Pesquisas em Atencao ao Uso de Drogas,; University of Rio de Janeiro, Brazil.; Data from various countries show considerable variation in the rate of spread of the human immunodeficiency virus (HIV) among drug injectors. Although further research is needed to predict the rate of increase of seroprevalence at Rio de Janeiro, preliminary data confirm the presence of the virus, with a seroprevalenc
Transmission of HIV among drug addicts in three French cities: implications for prevention.: Bull Narc. 1993;45(1):117-34. Unique Identifier : AIDSLINE MED/94138312; Ingold FR; Toussirt M; Institute for Epidemiological Research on Drug Dependence, Paris.; In 1988, the Institute for Epidemiological Research on Drug Dependence conducted an ethnographic study designed to assess the results of liberalization of the sale of syringes. In that study, drug addicts were found to have gradually altered their customary practices by limiting the sharing of syringes. Two years late
HIV infection among drug abusers in the Belgrade area.: Bull Narc. 1993;45(1):135-46. Unique Identifier : AIDSLINE MED/94138313; Kilibarda M; Institute on Addictions, Belgrade.; The abuse of heroin and other opiates by intravenous injection is identified as the major risk for the spread of infection by the human immunodeficiency virus (HIV) and of acquired immunodeficiency syndrome (AIDS) to the population at large. From 1980 to 1992, 2,712 opiate-addicted intravenous drug users with severe c
An international comparative study of HIV prevalence and risk behaviour among drug injectors in 13 cities. WHO Collaborative Study Group.: Bull Narc. 1993;45(1):19-46. Unique Identifier : AIDSLINE MED/94138314; Although reported rates of human immunodeficiency virus (HIV) infection and related risk behaviours among drug injectors vary considerably throughout the world, and comparison of findings is often hampered by methodological variability among centres. In 1989 the World Health Organization
The global diffusion of injecting drug use: implications for human immunodeficiency virus infection.: Bull Narc. 1993;45(1):3-17. Unique Identifier : AIDSLINE MED/94138315; Stimson GV; Department of Psychiatry, Charing Cross and Westminster Medical; School, London.; Long-standing patterns of drug injecting in mainly developed countries have been joined by the introduction and expansion of drug injecting in developing countries, often followed quickly by outbreaks of human immunodeficiency virus (HIV) infection. Drug injecting has been identified in 80 countries and HIV infection
Strategies for the prevention of HIV infection among and from injecting drug users.: Bull Narc. 1993;45(1):47-60. Unique Identifier : AIDSLINE MED/94138316; Wodak A; Des Jarlais DC; Alcohol and Drug Service, St. Vincent's Hospital, Darlinghurst,; New South Wales, Australia.; Despite a substantial reduction in the level of high-risk behaviours among injecting drug users (IDUs) documented in an impressive number of studies from many countries, human immunodeficiency virus (HIV) infection continues to spread among and from this population, reflecting the high baseline levels of these risk be
Critical issues regarding AIDS among injecting drug users.: Bull Narc. 1993;45(1):61-75. Unique Identifier : AIDSLINE MED/94138317; Des Jarlais DC; Friedman SR; Beth Israel Medical Center, New York, N.Y.; The paper identifies and reviews some critical issues in the field of human immunodeficiency virus (HIV) transmission among intravenous drug users. First, it discusses political denial and compartmentalization of the problem, giving an example from the United States that illustrates th
Drug injecting and HIV infection among the population of drug abusers in Asia.: Bull Narc. 1993;45(1):77-90. Unique Identifier : AIDSLINE MED/94138318; Poshyachinda V; Institute of Health Research, Chulalongkorn University, Bangkok.; Opium has been produced and consumed since the nineteenth century in the areas of Asia currently referred to as the Golden Crescent and the Golden Triangle. In the 1970s and 1980s, most countries from Afghanistan to Japan experienced a heroi
Rapid spread of HIV among injecting drug users in north-eastern states of India.: Bull Narc. 1993;45(1):91-105. Unique Identifier : AIDSLINE MED/94138319; Sarkar S; Das N; Panda S; Naik TN; Sarkar K; Singh BC; Ralte JM; Aier SM; Tripathy SP; Indian Council of Medical Research Unit for Research on AIDS in; North-Eastern States of India, Calcutta.; Manipur, a north-eastern state of India bordering Myanmar , has experienced very rapid transmission of the human immunodeficiency virus (HIV) among its vast drug-injecting population. Seroprevalence among intravenous drug users increased from 0 p
Cesarean section to reduce perinatal transmission of human immunodeficiency virus. A metaanalysis.: Online J Curr Clin Trials. 1993 Jul 8;Doc No 74:[5107 words; 46 paragraphs]. Unique Identifier : AIDSLINE MED/94138571; Villari P; Spino C; Chalmers TC; Lau J; Sacks HS; Technology Assessment Group, Harvard School of Public Health,; Boston, MA 02115.; OBJECTIVE: Individual epidemiologic investigations into the association between type of delivery and perinatal HIV transmission have been suggestive but inconclusive. Metaanalysis was used in an attempt to establish if there is, at present, adequate evidence concerning the effectiveness of cesarean section in reducing
Treatment of early or asymptomatic HIV infection. Where are we and where do we go from here? [editorial]: Online J Curr Clin Trials. 1993 Oct 7;Doc No 93:[898 words; 7 paragraphs]. Unique Identifier : AIDSLINE MED/94138579; Sacks HS
Abnormal lipid composition of bronchoalveolar lavage fluid obtained from individuals with AIDS-related lung disease.: Am J Respir Crit Care Med. 1994 Feb;149(2 Pt 1):332-8. Unique Identifier : AIDSLINE MED/94138591; Rose RM; Catalano PJ; Koziel H; Furlong ST; Division of Pulmonary and Critical Care Medicine, New England; Deaconess Hospital, Boston, Massachusetts.; Surfactant lipids are not only important to the physiologic function of the lungs, but may also influence disease processes like Pneumocystis pneumonia, in which the interaction of host-defense cells with pathogen occurs within the confines of the surfactant-rich alveolar hypophase. In the present studies the lipid pr
Psychiatric morbidity in sentenced segregated HIV-positive prisoners.: Br J Psychiatry. 1993 Dec;163:802-5. Unique Identifier : AIDSLINE MED/94138702; Dorman A; O'Connor A; Hardiman E; Freyne A; O'Neill H; Central Mental Hospital, Dundrum, Dublin, Republic of Ireland.; In this comparative study with a control group of prisoners, psychiatric morbidity was measured in two groups of sentenced prisoners, each group completing the GHQ-30 and 21-item Beck Depression Inventory (BDI). Group 1 consisted of 40 segregated HIV-positive prisoners and group 2 a matched control group in the main p
Suppurative epididymo-orchitis in young high risk patients--a new problem?: Br J Urol. 1993 Dec;72(6):949-51. Unique Identifier : AIDSLINE MED/94138747; Parr NJ; Prasad BR; Hayhurst V; McMillan A; Leen CS; Fowler JW; Department of Urology, Western General Hospital, Edinburgh.; During a 4-year period we have treated 3 young patients with severe epididymo-orchitis which progressed to suppuration (despite treatment with a range of antibiotics) and necessitated orchiectomy. All gave a history of high risk activity (2 homosexual, 1 sexual partner of intravenous drug user). One patient was suffer
Use of the cytomegalovirus antigenemia (CMV-Ag) assay for the detection of CMV in the blood of AIDS patients.: Can J Microbiol. 1993 Nov;39(11):1059-65. Unique Identifier : AIDSLINE MED/94138794; Lipson SM; Kaplan MH; Tseng LF; Mandel FS; Jane and Dayton Brown and Dayton T. Brown, Jr., Virology; Laboratory, Department of Medicine, North Shore University; Hospital-Cornell University Medical College, Manhasset, NY 11030.; Direct specimen testing was performed on 186 peripheral blood specimens to identify the presence of antigen to cytomegalovirus (viz., the cytomegalovirus antigenemia (CMV-Ag) assay). Confirmatory testing was performed using the shell vial indirect immunofluorescence assay (SVA-IFA)
Knowledge and attitudes on AIDS relevant for the establishment of community care in the city of Harare.: Cent Afr J Med. 1993 Mar;39(3):45-9. Unique Identifier : AIDSLINE MED/94138991; Moyo I; Low A; Ray CS; Katsumbe TM; Chisvo D; Mbengeranwa OL; Gumbo N; Part I: Because of the increasing number of people with the HIV infection or AIDS, health resources and facilities are becoming over burdened. Many projects are looking towards involving communities more in caring and supporting those living with HIV/AIDS. In view of this, features of knowledge and attitudes have been
FDA reiterates personal-use importation policy to buyers' clubs [news]: Clin Pharm. 1993 Sep;12(9):636-7. Unique Identifier : AIDSLINE MED/94139193
Surveillance study adds to database on seroconversion rates and zidovudine use after occupational exposures [news]: Clin Pharm. 1993 Sep;12(9):636-7. Unique Identifier : AIDSLINE MED/94139194
Incidence of cardiac arrhythmias during intravenous pentamidine therapy in HIV-infected patients.: Chest. 1994 Feb;105(2):389-95. Unique Identifier : AIDSLINE MED/94139390; Eisenhauer MD; Eliasson AH; Taylor AJ; Coyne PE Jr; Wortham DC; Department of Medicine, Walter Reed Army Medical Center,; Washington, DC.; STUDY OBJECTIVE: There have been 15 published cases of probable pentamidine-induced torsade de pointes (TdP). A prospective analysis of this complication of therapy is valuable considering the high frequency of Pneumocystis carinii pneumonia in the AIDS population, and the role of pentamidine in its therapy. DESIGN: O
Regional deposition and regional ventilation during inhalation of pentamidine.: Chest. 1994 Feb;105(2):396-401. Unique Identifier : AIDSLINE MED/94139391; O'Riordan TG; Smaldone GC; Division of Pulmonary/Critical Care Medicine, State University of; New York at Stony Brook.; In most patients, the deposition of aerosolized pentamidine (AP) is less in the apex of the lung relative to the base. As the apex of the lung is relatively less ventilated than the base, it is possible that reduced regional ventilation may explain the inhomogeneity in regional drug deposition. The purpose of this stu
Rapid clinical diagnosis of pulmonary abnormalities in HIV-seropositive patients by auscultatory percussion.: Chest. 1994 Feb;105(2):402-7. Unique Identifier : AIDSLINE MED/94139392; Nelson RS; Rickman LS; Mathews WC; Beeson SC; Fullerton SC; University of California, School of Medicine, San Diego.; A prospective, blinded study of pulmonary findings in hospitalized patients with HIV infection compared auscultatory percussion (AusP) with conventional percussion (ConP) and conventional auscultation (ConA) using chest radiographs as the gold standard. Sixty-three patients had chest radiographs and were examined by o
Fiberoptic bronchoscopy in the evaluation of carcinoma metastatic to the lung.: Chest. 1994 Feb;105(2):454-7. Unique Identifier : AIDSLINE MED/94139403; Argyros GJ; Torrington KG; Department of Medicine, Walter Reed Army Medical Center,; Washington, DC 20307.; To determine the clinical presentation of patients with malignancies metastatic to the lung, the diagnostic utility of fiberoptic bronchoscopy (FB), and the primary site of malignancies metastasizing endobronchially, we retrospectively reviewed 1,853 FB records (1987 to 1991) and selected 111 cases for review. Cases w
Staphylococcus aureus pericarditis in HIV-infected patients.: Chest. 1994 Feb;105(2):615-6. Unique Identifier : AIDSLINE MED/94139437; Decker CF; Tuazon CU; Division of Infectious Diseases, National Naval Medical Center,; Bethesda, Md.; Serious infections caused by Staphylococcus aureus in HIV-infected patients have been reported. Contributing factors in the development of invasive S aureus infections include a high rate of skin and nasal colonization, frequent dermatologic disease, and the use of intravenous catheters. The authors report three cases
Syphilitic pneumonitis in an HIV-infected patient.: Chest. 1994 Feb;105(2):629-31. Unique Identifier : AIDSLINE MED/94139444; Dooley DP; Tomski S; Department of Medicine, Brooke Army Medical Center, Houston,; Texas.; Pneumonitis and symptomatic hepatitis are very rare complications of syphilis. Symptomatic hepatitis and subclinical reticulonodular pulmonary infiltrates were observed when an HIV-infected patient presented with secondary syphilis. The Jarisch-Herxheimer reaction included a flare of hepatitis symptoms, resembling cho
Women, contraception and HIV.: Drug Ther Bull. 1993 Dec 6;31(25):97-8. Unique Identifier : AIDSLINE MED/94139523
In vitro manipulation of early mouse embryos induces HIV1-LTRlacZ transgene expression.: Development. 1993 Dec;119(4):1293-300. Unique Identifier : AIDSLINE MED/94139569; Vernet M; Cavard C; Zider A; Fergelot P; Grimber G; Briand P; Institut Cochin de Genetique Moleculaire, Laboratoire de; Genetique et Pathologie Experimentales-CJF INSERM 90-03,; Paris, France.; We report here that the transcriptional activity of early mouse embryos is affected by their manipulation and culture in vitro, using transgenic embryos that express the reporter gene lacZ. We examined the pattern of expression of the lacZ gene fused to the human immunodeficiency virus type 1 long terminal repeat duri
Sexually transmitted and genital tract infections during pregnancy.: Emerg Med Clin North Am. 1994 Feb;12(1):91-113. Unique Identifier : AIDSLINE MED/94139637; Martens KA; Loyola University Stritch School of Medicine, Maywood, Illinois.; Sexually transmitted diseases comprise one of the most common medical complications of pregnancy. Prompt treatment is essential to minimize the risk of fetal and neonatal adverse consequences. At this time, however, no pharmacologic therapy is routinely employed for the viral STDs during pregnancy, including HIV, HSV,
Secondary structure and signal assignments of human-immunodeficiency-virus-1 protease complexed to a novel, structure-based inhibitor.: Eur J Biochem. 1994 Jan 15;219(1-2):707-12. Unique Identifier : AIDSLINE MED/94139754; Yamazaki T; Nicholson LK; Torchia DA; Stahl SJ; Kaufman JD; Wingfield PT; Domaille PJ; Campbell-Burk S; Bone Research Branch, National Institute of Dental Research, NIH,; Bethesda, MD 20892.; We report comprehensive NMR studies in solution of the human-immunodeficiency-virus (HIV)-1 protease. Stable solutions of the protease were obtained by complexing the protein to a designed cyclic urea inhibitor DMP 323. A variety of triple-resonance experiments provided essentially complete 1H, 13C and 15N NMR signal
Coxiella burnetii infection among subjects infected with HIV type 1 in the Central African Republic.: Eur J Clin Microbiol Infect Dis. 1993 Oct;12(10):775-8. Unique Identifier : AIDSLINE MED/94139767; Belec L; Gresenguet G; Ekala MT; Jacob A; Vohito MD; Cotigny S; Payan C; Laboratoire de Microbiologie, Hopital Broussais, Paris, France.; Sixty-six sera from HIV-1-seropositive adult African subjects and 49 sera from HIV-seronegative age and sex matched healthy African controls living in Bangui, Central African Republic , were screened for Coxiella burnetii antibody by an indirect immunofluorescent ant
Disseminated histoplasmosis in an AIDS patient in Spain [letter]: Eur J Clin Microbiol Infect Dis. 1993 Oct;12(10):793-4. Unique Identifier : AIDSLINE MED/94139775; Alados JC; Miranda C; Ortiz F; Cano R
Use of the arbitrary primer polymerase chain reaction for investigating an outbreak of Clostridium difficile-associated diarrhea in AIDS patients [letter]: Eur J Clin Microbiol Infect Dis. 1993 Oct;12(10):794-5. Unique Identifier : AIDSLINE MED/94139776; Barbut F; Mario N; Frottier J; Petit JC
The origin of human immunodeficiency virus type-1 rev gene. An evolutionary hypothesis.: FEBS Lett. 1994 Jan 31;338(2):118-21. Unique Identifier : AIDSLINE MED/94139907; Kubota S; Oroszlan S; Hatanaka M; Laboratory of Molecular Virology and Carcinogenesis,; NCI-Frederick Cancer Research and Development Center, MD; 21702-1201.; The Rev protein of human immunodeficiency virus type-1 is an RNA-binding posttranscriptional transregulator encoded by an accessory gene that is distinct from retroviral oncogenes and whose origin is unclear. We hypothesize that the rev gene was generated by duplication of a viral RNA segment having a secondary-struct
Effects of calcium ions on proteolytic processing of HIV-1 gp160 precursor and on cell fusion.: FEBS Lett. 1994 Feb 7;338(3):281-4. Unique Identifier : AIDSLINE MED/94139940; Moulard M; Montagnier L; Bahraoui E; Laboratorie de Biochimie, CNRS URA 1455-Ingenierie des; Proteines, Faculte de Medecine Secteur Nord, Marseille,; France.; Complete activation of human immunodeficiency virus type 1 (HIV-1) requires the endoproteolytic cleavage by cellular protease of the envelope glycoprotein precursor (gp160) into the external glycoprotein gp120, and the transmembrane glycoprotein gp41. We report here the effect of depletion of cellular calcium ions on
A model integrating mental health and primary care services for families with HIV.: Gen Hosp Psychiatry. 1993 Sep;15(5):290-300. Unique Identifier : AIDSLINE MED/94140102; Feingold A; Slammon WR; Division of Psychiatry, Boston City Hospital, Boston University; School of Medicine, MA 02118.; The need to integrate mental health and primary care service delivery for individuals and families living with human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) has been well documented. Accessibility, flexibility, and cultural specificity are qualities necessary, but generally lacking,
[Contact lenses--medical indications and problems]: Fortschr Med. 1993 Nov 30;111(33):517-21. Unique Identifier : AIDSLINE MED/94140302; Roth HW; Institut fur wissenschaftliche Kontaktoptik, Ulm Donau.; Today, hard and soft contact lenses are useful visual aids. In common with any other effective medication, however, they can also produce side effects. They are medically indicated whenever spectacles fail to optimally compensate poor vision. They are not easy to customize, and wearers must be examined by the ophthalm
[Viral safety of blood and blood products]: Fortschr Med. 1993 Nov 30;111(33):526-7. Unique Identifier : AIDSLINE MED/94140304; Gurtler L
[BCG immunization of newly infected HIV patients?]: Fortschr Med. 1993 Dec 10;111(34):49. Unique Identifier : AIDSLINE MED/94140307; Gericke D
[Viral infections--clinical pictures and laboratory diagnosis. Part 5: Human immunodeficiency virus (HIV 1, HIV 2) to measles virus]: Fortschr Med. 1993 Dec 20;111(35-36):559-61. Unique Identifier : AIDSLINE MED/94140314; Burkhardt U; Eggers HJ; Hygienisch-bakteriologisches Landesuntersuchungsamt, Nordrhein,; Universitat Koln.
Quantitative estimates for the effects of AIDS public education on HIV infections.: Int J Biomed Comput. 1993 Nov;33(3-4):157-77. Unique Identifier : AIDSLINE MED/94140461; Fan DP; Department of Genetics and Cell Biology, University of Minnesota,; St. Paul 55108.; Previous projections of HIV infection have not accounted explicitly for AIDS public information. The present analysis does so, using computer content analysis of AIDS news stories to make time trend forecasts of both HIV infection and knowledge, attitudes, and sexual behaviors relevant to AIDS. The data show that ther
Risk dimensions of HIV-tested substance users.: Int J Addict. 1993 Dec;28(14):1487-95. Unique Identifier : AIDSLINE MED/94140472; Ottomanelli G; State University of New York, Health Science Center, Brooklyn; 11203.; Methadone outpatients (n = 177) and outpatients enrolled in a nonchemotherapy (n = 65) counseling unit requested HIV testing. A HIV risk-related questionnaire elicited information on needle-sharing, drug injecting, sexual behaviors, and other risk activities. Although age and geographical seroprevalence were not signi
Depression as an antecedent of frequency of intravenous drug use in an urban, nontreatment sample.: Int J Addict. 1993 Dec;28(14):1601-12. Unique Identifier : AIDSLINE MED/94140479; Latkin CA; Mandell W; Department of Mental Hygiene, School of Hygiene and Public; Health, Johns Hopkins University, Baltimore, Maryland 21205.; The present study examined the relationship between depressive symptoms and frequency of drug use in 91 low income nontreatment intravenous drug users in Baltimore, Maryland. The majority of participants were injecting both heroin and cocaine. Scores on the depression scale at both waves were correlated with frequency
A phantasy of infection.: Int J Psychoanal. 1993 Oct;74 ( Pt 5):965-74. Unique Identifier : AIDSLINE MED/94140518; Grosz S; A phantasy of infection is a case study of the role of unconscious phantasy in the experience of illness. This paper discusses a phantasy that was brought to light during the psychoanalysis of a homosexual man who has been diagnosed as HIV-positive. The paper concentrates on the difference between this patient s con
If only AIDS were different!: Hastings Cent Rep. 1993 Nov-Dec;23(6):6-12. Unique Identifier : AIDSLINE MED/94140566; Harris J; Holm S; Centre for Social Ethics and Policy, University of Manchester,; United Kingdom.
Drug injectors in Glasgow: a community at risk? A report from a multidisciplinary group. The Possilpark Group.: Health Bull (Edinb). 1993 Nov;51(6):418-29. Unique Identifier : AIDSLINE MED/94140573; In 1987 it became apparent that the number of drug injectors with HIV infection living in a district in the north of Glasgow was increasing. As this area was well served by a wide variety of clinical, epidemiological and laboratory facilities, a multidisciplinary group was convened to examine the extent and spread of
AIDS and the African American woman: the triple burden of race, class, and gender.: Health Educ Q. 1993 Fall;20(3):305-20; discussion 321-6. Unique Identifier : AIDSLINE MED/94140575; Quinn SC; Department of Health Education, University of Maryland, College; Park, MD 20742.; The disproportionate impact of human immunodeficiency syndrome (HIV) disease on African American women is devastating to their lives, their families, their communities, and our society. Among AIDS cases in women, 52.5% are black. African American women with HIV disease constitute one of the least powerful and most bur
Using focus groups to develop health surveys: an example from research on social relationships and AIDS-preventive behavior.: Health Educ Q. 1993 Fall;20(3):361-72. Unique Identifier : AIDSLINE MED/94140578; O'Brien K; Department of Psychology, Portland State University, OR; 97207-0751.; Focus group data can inform the choice of words or phrases in a questionnaire, the construction of items to measure a given concept, the formation of new hypotheses, and the development of survey procedures. To date, few examples exist to show researchers in health behavior and health education how they might use focu
Factors associated with AIDS-related behavioral intentions among high school students in an AIDS epicenter.: Health Educ Q. 1993 Fall;20(3):409-20. Unique Identifier : AIDSLINE MED/94140581; Walter HJ; Vaughan RD; Gladis MM; Ragin DF; Kasen S; Cohall AT; Center for Population and Family Health, Columbia University; School of Public Health, New York, NY 10032.; Using data from a cross-sectional survey of 531 predominantly black and Hispanic 10th graders in two New York City schools, the explanatory power of predictors of intentions to engage in sexual intercourse, to have multiple intercourse partners, and to use condoms was compared. Theoretically derived predictor variable
Assessing the stages of change and decision-making for contraceptive use for the prevention of pregnancy, sexually transmitted diseases, and acquired immunodeficiency syndrome.: Health Educ Q. 1993 Winter;20(4):455-70. Unique Identifier : AIDSLINE MED/94140584; Grimley DM; Riley GE; Bellis JM; Prochaska JO; Cancer Prevention Research Center, University of Rhode Island,; Kingston 02881-0808.; A synergistic approach was taken to examine contraceptive use adoption for two related behaviors: pregnancy prevention and the prevention of sexually transmitted diseases (STDs), including human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS). One hundred twenty-three young adults responded to q
Findings from the Horizontes Acquired Immune Deficiency Syndrome Education project: the impact of indigenous outreach workers as change agents for injection drug users.: Health Educ Q. 1993 Winter;20(4):523-38. Unique Identifier : AIDSLINE MED/94140588; Birkel RC; Golaszewski T; Koman JJ 3rd; Singh BK; Catan V; Souply K; Koba Institute, Washington, DC 20005.; A human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) intervention using indigenous outreach workers was implemented with Hispanic injection drug users (IDUs) and their sexual partners in three locations: Laredo, Texas; San Diego, California; and San Juan,
Efficacy of a home-based human immunodeficiency virus prevention video program for teens and parents.: Health Educ Q. 1993 Winter;20(4):555-67. Unique Identifier : AIDSLINE MED/94140590; Winett RA; Anderson ES; Moore JF; Taylor CD; Hook RJ; Webster DA; Neubauer TE; Harden MC; Mundy LL; Virginia Polytechnic Institute and State University, Department; of Psychology, Blacksburg 24061-0436.; Family-based communication about sexual behavior and sexuality is a predominate theme in the key risk reduction and service objectives for human immunodeficiency virus (HIV) prevention and related issues in Healthy People 2000. These recommendations are particularly poignant for younger adolescents who are not yet sex
Differences in the central major histocompatibility complex between humans and chimpanzees. Implications for development of autoimmunity and acquired immune deficiency syndrome.: Hum Immunol. 1993 Sep;38(1):30-41. Unique Identifier : AIDSLINE MED/94140612; Leelayuwat C; Zhang WJ; Abraham LJ; Townend DC; Gaudieri S; Dawkins RL; Department of Clinical Immunology, Royal Perth Hospital, Western; Australia.; Chimpanzees (Pan Troglodytes) and humans are closely related and belong to the same subfamily, Homininae. The approximately 1.8% genetic difference that exists between humans and the chimpanzees must be responsible for observed differences between these two species. It has been shown that chimpanzees can be infected w
Viral long terminal repeat substrate binding characteristics of the human immunodeficiency virus type 1 integrase.: J Biol Chem. 1994 Feb 11;269(6):3999-4004. Unique Identifier : AIDSLINE MED/94140811; Hazuda DJ; Wolfe AL; Hastings JC; Robbins HL; Graham PL; LaFemina RL; Emini EA; Merck Research Laboratories, West Point, Pennsylvania 19486.; A DNA binding assay was developed for the human immunodeficiency virus type 1 (HIV-1) integrase. The assay was capable of defining discrete complexes between the enzyme and the viral long terminal repeat (LTR) substrate. DNA binding reflected the sequence requirements previously demonstrated for the enzyme s 3 -end pr
HIV-induced syncytia of a T cell line form single giant pseudopods and are motile.: J Cell Sci. 1993 Nov;106 ( Pt 3):941-53. Unique Identifier : AIDSLINE MED/94140946; Sylwester A; Wessels D; Anderson SA; Warren RQ; Shutt DC; Kennedy RC; Soll DR; Department of Biological Sciences, University of Iowa, Iowa City; 52242.; The human immunodeficiency virus, HIV, induces syncytium formation in cultures of many T cell lines. These syncytia have previously been viewed as disorganized fusion products in the throes of death. Evidence is presented that in HIV1-infected SupT1 cultures, syncytia five times to over one hundred times larger than s
Establishment of a quality assurance program for human immunodeficiency virus type 1 DNA polymerase chain reaction assays by the AIDS Clinical Trials Group. ACTG PCR Working Group, and the ACTG PCR Virology Laboratories.: J Clin Microbiol. 1993 Dec;31(12):3123-8. Unique Identifier : AIDSLINE MED/94140978; Jackson JB; Drew J; Lin HJ; Otto P; Bremer JW; Hollinger FB; Wolinsky SM; Institute of Pathology, Case Western Reserve University,; Cleveland, Ohio 44106.; An independent quality assurance program has been established by the Virology Committee of the AIDS Clinical Trials Group in the Division of AIDS, National Institute of Allergy and Infectious Diseases, for monitoring polymerase chain reaction (PCR) assays for human immunodeficiency virus type 1 (HIV-1) DNA that are pe
Isolation of Mycobacterium avium complex from water in the United States, Finland, Zaire, and Kenya.: J Clin Microbiol. 1993 Dec;31(12):3227-30. Unique Identifier : AIDSLINE MED/94140996; von Reyn CF; Waddell RD; Eaton T; Arbeit RD; Maslow JN; Barber TW; Brindle RJ; Gilks CF; Lumio J; Lahdevirta J; et al; Infectious Disease Section, Dartmouth-Hitchcock Medical Center,; Lebanon, New Hampshire 03756.; Disseminated infection with organisms of the Mycobacterium avium complex (MAC) is a common complication of AIDS in the United States and other developing countries, but it is rare or absent in sub-Saharan Africa. To assess the comparative likelihood of exposure to MAC in these geograph
Karyotyping of Cryptococcus neoformans as an epidemiological tool.: J Clin Microbiol. 1993 Dec;31(12):3305-9. Unique Identifier : AIDSLINE MED/94141008; Perfect JR; Ketabchi N; Cox GM; Ingram CW; Beiser CL; Department of Medicine, Duke University Medical Center, Durham,; North Carolina 27710.; Karyotyping of Cryptococcus neoformans var. neoformans can be used as an epidemiological tool for C. neoformans infections. In this study of over 40 isolates from both clinical and environmental sources, 90% had a unique chromosome banding by pulsed-field electrophoresis. There was no conserved pattern associated with
Virological diagnosis of progressive multifocal leukoencephalopathy: detection of JC virus DNA in cerebrospinal fluid and brain tissue of AIDS patients.: J Clin Microbiol. 1993 Dec;31(12):3310-3. Unique Identifier : AIDSLINE MED/94141009; Moret H; Guichard M; Matheron S; Katlama C; Sazdovitch V; Huraux JM; Ingrand D; Laboratoire de Microbiologie, Hopital Robert Debre, Reims,; France.; Cerebrospinal fluid (CSF) from 12 AIDS patients with clinical signs consistent with progressive multifocal leukoencephalopathy (PML) was examined by the polymerase chain reaction (PCR) for the presence of JC virus (JCV). A specific JCV target sequence was amplified in the CSF from 9 of the 12 patients and also in brai
A clinicopathologic study of ten patients with recurrent unexplained flushing.: J Allergy Clin Immunol. 1994 Jan;93(1 Pt 1):53-60. Unique Identifier : AIDSLINE MED/94141071; Friedman BS; Germano P; Miletti J; Metcalfe DD; Mast Cell Physiology Section, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, Md; 20892.; We describe the clinicopathologic features of 10 patients with recurrent unexplained flushing. These patients were referred to the National Institutes of Health with a diagnosis of mastocytosis or idiopathic anaphylaxis. Both diagnoses were eliminated after evaluation. Patients reported attacks of flushing lasting 15
Primary Kaposi's sarcoma of the gallbladder in AIDS.: J Clin Gastroenterol. 1993 Dec;17(4):352-3. Unique Identifier : AIDSLINE MED/94141122; Lesman AJ; Golub R; Giron JA; Ilardi CF; Department of Medicine, Flushing Hospital Medical Center, New; York.
Experience with the hemophiliac child in a pediatric emergency department.: J Emerg Med. 1993 Sep-Oct;11(5):519-24. Unique Identifier : AIDSLINE MED/94141125; Morgan LM; Kissoon N; de Vebber BL; Department of Pediatrics, University of Western Ontario, London,; Canada.; We conducted a retrospective chart review of all hemophiliacs followed by our pediatric hematology service from January 1, 1980 to December 31, 1989 inclusive, to determine the frequency and nature of their visits to our Emergency Department (ED). Of 36 patients studied, 26 were Factor VIII deficient (13 mild, 3 moder
Comparison of a lysed whole blood method to purified cell preparations for lymphocyte immunophenotyping: differences between healthy controls and HIV-positive specimens.: J Immunol Methods. 1994 Jan 3;167(1-2):237-43. Unique Identifier : AIDSLINE MED/94141199; Tamul KR; O'Gorman MR; Donovan M; Schmitz JL; Folds JD; Clinical Microbiology-Immunology Laboratory, University of North; Carolina Hospitals, Chapel Hill 27514.; Although the majority of clinical laboratories now use a lysed whole blood (LWB) method for routine immunophenotyping, researchers wishing to perform other types of studies with lymphocytes from HIV+ patients may still need to use purified cell preparations, such as peripheral blood mononuclear cells (PBMC). A compari
Ability of 'OptiLyse' lysing/fixing reagents to inactivate HIV-infected H9 cells in whole blood [letter]: J Immunol Methods. 1994 Feb 10;168(2):283-4. Unique Identifier : AIDSLINE MED/94141229; Nicholson JK; Browning SW
Human microsporidiosis.: J Infect. 1993 Nov;27(3):229-36. Unique Identifier : AIDSLINE MED/94141239; Curry A; Canning EU; Public Health Laboratory, Withington Hospital, Manchester, U.K.
Septicaemia in patients with and without AIDS at Westminster Hospital, London.: J Infect. 1993 Nov;27(3):243-50. Unique Identifier : AIDSLINE MED/94141241; Hickey MM; Shanson DC; Department of Medical Microbiology, Chelsea and Westminster; Hospital, London, U.K.; The types of organism causing septicaemia in patients with AIDS and without AIDS at Westminster Hospital were examined prospectively over a period of 2 years (1990-1991). Altogether 417 episodes of septicaemia were diagnosed, 148 (35%) of which were in patients with AIDS. Of septicaemias in patients with AIDS, 53 (36%
Measles, mumps and rubella immunisation in children at risk of infection with human immunodeficiency virus.: J Infect. 1993 Nov;27(3):251-3. Unique Identifier : AIDSLINE MED/94141242; Molyneaux PJ; Mok JY; Burns SM; Yap PL; Regional Virus Laboratory, City Hospital, Edinburgh, U.K.; A retrospective serological study of 81 children at risk of HIV (II HIV-infected, 70 HIV-negative) was performed to assess susceptibility to measles, mumps and rubella and response to measles, mumps and rubella (MMR) immunisation. There was no difference in the initial serological response between the HIV-infected and
Oesophageal ulcers in HIV-infected patients [letter; comment]: J Intern Med. 1994 Feb;235(2):191. Unique Identifier : AIDSLINE MED/94141434; Domingo P; Ris J; Baselga E; Puig M; Lopez-Contreras J
Blood in saliva of patients with acquired immunodeficiency syndrome: possible implication in sexual transmission of the disease.: J Med Virol. 1994 Jan;42(1):38-41. Unique Identifier : AIDSLINE MED/94141477; Piazza M; Chirianni A; Picciotto L; Cataldo PT; Borgia G; Orlando R; Institute of Infectious Diseases, University of Naples 2nd School; of Medicine, Italy.; The presence and concentration of haemoglobin in saliva of anti-human immunodeficiency virus (HIV) positive subjects, anti-HIV-negative subjects at high risk of infection, and healthy controls were studied. One hundred eighty-eight subjects were anti-HIV-positive intravenous drug abusers (IVDA), 22 were anti-HIV-posit
Cytomegaloviral infection of the mandible in acquired immunodeficiency syndrome.: J Oral Maxillofac Surg. 1994 Mar;52(3):305-8. Unique Identifier : AIDSLINE MED/94141613; Flaitz CM; Hicks MJ; Nichols CM; Department of Oral Diagnostic Sciences, University of Texas; Health Science Center Dental Branch, Houston 77225-0068.
Orofacial granulomatosis: report of a case with decreased CD4/CD8 ratio.: J Oral Maxillofac Surg. 1994 Mar;52(3):317-22. Unique Identifier : AIDSLINE MED/94141616; Henry CH; Department of Dentistry, Medical Center of Delaware, Wilmington.
Rheumatic manifestations in human immunodeficiency virus positive and negative individuals: a study of 2 populations with similar risk factors.: J Rheumatol. 1993 Nov;20(11):1880-4. Unique Identifier : AIDSLINE MED/94141789; Medina-Rodriguez F; Guzman C; Jara LJ; Hermida C; Alboukrek D; Cervera H; Miranda JM; Fraga A; Rheumatic Diseases Unit, Hospital de Especialidades, Mexico City,; Mexico.; OBJECTIVE. Assess the impact of human immunodeficiency virus (HIV) infection on the onset of rheumatic manifestations in HIV+ patients, and to compare them with a control HIV- group with similar risk factors. METHODS. We prospectively studied 74 consecutive HIV+ patients, looking for clinical and laboratory findings o
Association of methotrexate treatment with a decrease of double negative (CD4-CD8-) and gamma/delta T cell levels in patients with juvenile rheumatoid arthritis.: J Rheumatol. 1993 Nov;20(11):1944-8. Unique Identifier : AIDSLINE MED/94141801; Massa M; de Benedetti F; Robbioni P; Ramenghi B; Albani S; Martini A; Clinica Pediatrica, Universita di Pavia, I.R.C.C.S., Policlinico; S. Matteo, Italy.; OBJECTIVE. It has been suggested that double negative (CD4-CD8-) (DN) and gamma/delta T cells may be involved in some autoimmune diseases. We investigated peripheral blood DN and gamma/delta T cell levels in patients with active juvenile rheumatoid arthritis (JRA). METHODS. DN and gamma/delta T cell levels were measur
Drug misusers in police custody: a prospective survey [see comments]: J R Soc Med. 1994 Jan;87(1):13-4. Unique Identifier : AIDSLINE MED/94141843; Payne-James JJ; Dean PJ; Keys DW; Group IV Forensic Medical Research, Metropolitan Police Service,; London, UK.; Approximately 11% of individuals seen by forensic medical examiners in police custody in London are drug misusers. This prospective survey using an anonymized structured questionnaire attempted to define some of the characteristics of this selected group of drug misusers. The study was undertaken in Metropolitan Polic
Diagnosis of HIV in babies of HIV-infected mothers [news]: J R Soc Health. 1993 Dec;113(6):284. Unique Identifier : AIDSLINE MED/94141869
The clinical management of HIV-related dementia and other memory disorders in the residential drug treatment environment.: J Subst Abuse Treat. 1993 Nov-Dec;10(6):505-11. Unique Identifier : AIDSLINE MED/94141973; Orr DA; Pinto PF; H.E.L.P./Project Samaritan, Bronx, New York 10452.; Human immunodeficiency virus (HIV)-related dementia and other memory and attention disorders are described in terms of etiology, incidence, and symptoms. Assessment for cognitive impairment includes basic screening (examples are given), or a thorough neuropsychological evaluation.
Treatment and services for drug users in Britain.: J Subst Abuse Treat. 1993 Nov-Dec;10(6):561-7. Unique Identifier : AIDSLINE MED/94141980; Franey C; Power R; Wells B; Department of Psychiatry, Charing Cross and Westminster Medical; School, University of London, United Kingdom.; The pattern of British drug service provision was transformed during the late 1980s. Policy makers and service providers recognised the need for a more flexible response to changing drug trends and client needs; consequently community-based services proliferated. HIV has had considerable impact on the working approach
Simultaneous progressive multifocal leukoencephalopathy, Epstein-Barr virus (EBV) latent infection and cerebral parenchymal infiltration during chronic lymphocytic leukemia.: Leukemia. 1994 Feb;8(2):318-21. Unique Identifier : AIDSLINE MED/94142327; Farge D; Herve R; Mikol J; Sauvaget F; Ingrand D; Singer B; Ferchal F; Auperin I; Gray F; Sudaka A; et al; Department of Internal Medicine, Saint Louis Hospital, Paris VII; University, France.; We report a non-HIV patient who had B chronic lymphocytic leukemia (CLL) with progressive multifocal leukoencephalopathy (PML) and diffuse cerebral leukemic parenchymal infiltration in the presence of JC virus and Epstein-Barr virus (EBV) cerebral co-infection. Multiple subcortical hypodensities lining the cortico-sub
Ethical issues in Australian hospitals.: Med J Aust. 1994 Jan 17;160(2):63-5. Unique Identifier : AIDSLINE MED/94142624; McNeill PM; Walters JD; Webster IW; School of Community Medicine, University of New South Wales,; Kensington.; OBJECTIVE: To identify the most common ethical issues of concern in Australian hospitals. DESIGN: A descriptive study using data collected by means of a questionnaire. PARTICIPANTS: Seven hundred and thirty-nine (74%) hospital administrators and employees nominated by hospital administrators in Australian public and p
The doctor and the clinic: young people's experiences of HIV testing [letter]: Med J Aust. 1994 Feb 21;160(4):234. Unique Identifier : AIDSLINE MED/94142663; Ovenden C; Loxley W
HTLV-I and clinical disease correlates in central Australian aborigines [letter]: Med J Aust. 1994 Feb 21;160(4):238. Unique Identifier : AIDSLINE MED/94142671; Mollison LC
Health risk behaviors among adolescents who do and do not attend school--United States, 1992.: MMWR Morb Mortal Wkly Rep. 1994 Mar 4;43(8):129-32. Unique Identifier : AIDSLINE MED/94142721; High proportions of U.S. high school students engage in behaviors that place them at increased risk for the leading causes of death and morbidity (e.g., motor-vehicle crashes and other unintentional injuries, homicide, suicide, heart disease, and cancer), unintended pregnancy, and infection with human immunodeficiency
HIV or zidovudine myopathy? [letter; comment]: Neurology. 1994 Feb;44(2):360-1; discussion 362-4. Unique Identifier : AIDSLINE MED/94142929; Dalakas M
HIV or zidovudine myopathy? [letter; comment]: Neurology. 1994 Feb;44(2):361; discussion 362-4. Unique Identifier : AIDSLINE MED/94142930; Grau JM; Casademont J
HIV or zidovudine myopathy? [letter; comment]: Neurology. 1994 Feb;44(2):361; discussion 362-4. Unique Identifier : AIDSLINE MED/94142931; Kieburtz K
HIV or zidovudine myopathy? [letter; comment]: Neurology. 1994 Feb;44(2):361-2; discussion 362-4. Unique Identifier : AIDSLINE MED/94142932; Gherardi R; Chariot P
[Antiviral chemotherapy: mechanisms of action, evaluation of activity, resistance and future developments]: Pathol Biol (Paris). 1993 Oct;41(8 Pt 2):770-6. Unique Identifier : AIDSLINE MED/94143071; Agut H; Fillet AM; Huraux JM; Laboratoire de Bacteriologie-Virologie, CERVI, Hospitalier; Pitie-Salpetriere, Paris, France.; Antiviral chemotherapy is based on the selective inhibition of intracellular virus multiplication. Inhibitors of viral DNA polymerases perfectly exemplifies this mode of action. In spite of their selectivity, some of these drugs are cytotoxic and all remain unefficient against latent viruses. Evaluation of antiviral a
[Role of cytokines in the regulation of HIV expression]: Pathol Biol (Paris). 1993 Oct;41(8 Pt 2):777-80. Unique Identifier : AIDSLINE MED/94143072; Molina JM; Service des Maladies Infectieuses et Tropicales, Hopital; Saint-Louis, Paris.; The cytokine network, which is involved in the regulation of normal immune responses, may play a role in the pathogenesis of human immunodeficiency virus (HIV) infection, by altering the replication of HIV in target cells. In vitro data, suggest that certain cytokines like tumor necrosis factor alpha (TNF alpha) granu
[What is known about the cellular and molecular pharmacodynamics of nucleosides?]: Pathol Biol (Paris). 1993 Oct;41(8 Pt 2):781-7. Unique Identifier : AIDSLINE MED/94143073; Sommadossi JP; Departement de Pharmacologie, Universite d'Alabama, Birmingham; 35294.; 3 -azido-3 -deoxythymidine (zidovudine- AZT ) was the first clinically approved reverse transcriptase inhibitor for the treatment of acquired immunodeficiency syndrome (AIDS) and recently, 2 ,3 -dideoxyinosine (didanosine-ddI) has also been approved in
[Is resistance of human immunodeficiency viruses (HIV) to nucleoside analogs an indication for their combined use?]: Pathol Biol (Paris). 1993 Oct;41(8 Pt 2):788-93. Unique Identifier : AIDSLINE MED/94143074; Pepin JM; Simon F; Brun-Vezinet F; Laboratoire de Virologie, Hopital Bichat-Claude Bernard, Paris,; France.; HIV resistance to nucleoside analogues such as zidovudine ( AZT ) is to date a source of concern, even if its clinical significance is yet to be determined. Phenotypic and genotypic data concerning HIV resistance will be presented, then the potential be
[Are immunomodulators capable to improve the activity of nucleoside antiretroviral agents?]: Pathol Biol (Paris). 1993 Oct;41(8 Pt 2):794-8. Unique Identifier : AIDSLINE MED/94143075; Sinet M; Pocidalo JJ; Unite INSERM U 13, Paris, France.; Synthetic polyribonucleotides stimulate cells to produce interferons and other cytokines and increase both humoral and cell-mediated immunity. The polynucleotide complexes affect host defense system and may have antiviral properties. Studies in animal models of experimental viral infection may therefore be performed t
[Visceral leishmaniasis resistant to conventional treatments: value of amphotericin B]: Pathol Biol (Paris). 1993 Oct;41(8 Pt 2):817-9. Unique Identifier : AIDSLINE MED/94143078; Bernard E; Quaranta JF; Durant J; Le Fichoux Y; Dellamonica P; Maladies Infectieuses et Tropicales, Hopital de l'Archet, Nice,; France.; The reference treatment in visceral leishmaniasis is administration of antimonial compounds (Pentostam, Glucantime). Primary and secondary failures have been reported and may involve several mechanisms resulting in alterations in the T-cell-dependent response, particularly in HIV-positive patients. Alternative agents
Oral empirical treatment of pneumonia. The challenge of choosing the best agent.: Postgrad Med. 1994 Feb 1;95(2):165-72. Unique Identifier : AIDSLINE MED/94143248; Gleckman RA; Boston University School of Medicine.; Knowledge of the respiratory pathogens that cause pneumonia, combined with data obtained from the initial history, physical examination, and laboratory studies, provides the framework for an empirical approach to the treatment of community-acquired pneumonia. Selection of empirical therapy is based in large part on wh
AIDS-related knowledge, fear, and behavioral change among nurses in Taiwan.: Public Health Nurs. 1993 Dec;10(4):257-62. Unique Identifier : AIDSLINE MED/94143287; Wang JF; Simoni PS; Paterson J; School of Nursing, West Virginia University, Morgantown 26506.; Current literature documents a phenomenon of fear that affects the willingness of health care professionals to care for persons with acquired immunodeficiency syndrome (AIDS). We attempted to identify differences between nurses who exhibit fearful attitudes toward AIDS and those who do not, based on knowledge and beha
[Effect of a filter system on measurement data and bacterial contamination in lung function studies]: Pneumologie. 1993 Nov;47(11):626-30. Unique Identifier : AIDSLINE MED/94143320; Strauss R; Wasser F; Mueller RL; Reim E; Wirtz P; Hahn EG; Siegfried W; Medizinische Klinik I mit Poliklinik,; Friedrich-Alexander-Universitat Erlangen-Nurnberg.; 80 measurements of the airway resistance of 20 patients did not yield any significant differences with or without using a bacterial filter (Pall PF 30) (p = 0.1213). Likewise, lung function tests conducted in 61 further patients did not reveal any relevant changes caused by introducing the filter, in respect of the lu
[Double infection of the lung with Pneumocystis carinii and Cryptococcus neoformans in an AIDS patient]: Pneumologie. 1993 Nov;47(11):640-2. Unique Identifier : AIDSLINE MED/94143323; Albrecht H; Stellbrink HJ; Fenske S; Koperski K; Greten H; Medizinische Kernklinik und Poliklinik, Universitatskrankenhaus; Eppendorf, Hamburg.; A 25-year old HIV-1-positive hemophiliac was admitted with fever, cough, exertional dyspnea and pleuritic chest pain. Chest x-ray showed diffuse bilateral infiltrates with a left sided nodular consolidation. Pneumocystis-carinii-pneumonia was suspected and diagnosed by broncho-alveolar lavage. With therapy the diffuse
[Can atypical mycobacteria infections be treated? Diversity and complexity]: Rev Prat. 1993 Oct 1;43(15):1959-62. Unique Identifier : AIDSLINE MED/94143686; Dautzenberg B; Service de pneumologie, groupe hospitalier Pitie-Salpetriere,; Paris.
[Outbreak of malaria induced among users of injectable drugs]: Rev Saude Publica. 1993 Feb;27(1):9-14. Unique Identifier : AIDSLINE MED/94143707; Barata LC; Andriguetti MT; de Matos MR; SUCEN, Sao Paulo, Brasil.; Five cases of malaria were detected among cocaine users by the local health service in Bauru, a city with a population of 260,000, located 324 km from S. Paulo, Brazil , during the first three weeks of July 1990. Autochthonous malaria had not occurred in Bauru since 1978, and all th
... as French ponder hosting AIDS summit [news]: Science. 1994 Feb 18;263(5149):907. Unique Identifier : AIDSLINE MED/94143726
AIDS scandal embroils top French biologist... [news]: Science. 1994 Feb 18;263(5149):907. Unique Identifier : AIDSLINE MED/94143727
Starting a support group for families and partners of people with HIV/AIDS in a rural setting.: Soc Work. 1994 Jan;39(1):135-8. Unique Identifier : AIDSLINE MED/94143765; Anderson DB; Shaw SL; Monadnock Family Services, Keene, NH 03431.
Perspectives on AIDS control in Zambia [editorial]: S Afr Med J. 1993 Sep;83(9):633-4. Unique Identifier : AIDSLINE MED/94143797; Matondo P
The socio-economic determinants of the AIDS epidemic in South Africa--a cycle of poverty.: S Afr Med J. 1993 Sep;83(9):635-6. Unique Identifier : AIDSLINE MED/94143798; Evian C; Community AIDS Information and Support Centre, Johannesburg.
Paediatric HIV/AIDS in schools.: S Afr Med J. 1993 Sep;83(9):636-7. Unique Identifier : AIDSLINE MED/94143799; Gie RP; Schaaf HS; Barnes JM; Department of Paediatrics and Child Health, University of; Stellenbosch.
AIDS prevention in South Africa. A perspective from other African countries.: S Afr Med J. 1993 Sep;83(9):668-74. Unique Identifier : AIDSLINE MED/94143812; Wilson D; Lavelle S; Psychology Department, University of Zimbabwe, Harare.
AIDS education in schools--awareness, attitudes and opinions among educators, theology students and health professionals.: S Afr Med J. 1993 Sep;83(9):675-9. Unique Identifier : AIDSLINE MED/94143813; Jameson CP; Glover PH; Settlers' Hospital, Grahamstown.; A project was undertaken in Grahamstown to assess the level of AIDS awareness, attitudes towards AIDS and opinions as to how and whether education programmes for schoolchildren should be planned. Opinions were canvassed initially by means of a questionnaire to three groups of professionals who could become involved in
Under-reporting of AIDS [letter]: S Afr Med J. 1993 Sep;83(9):689-90. Unique Identifier : AIDSLINE MED/94143817; Stuart J
AIDS and the social irresponsibility of the insurance industry [letter]: S Afr Med J. 1993 Sep;83(9):690. Unique Identifier : AIDSLINE MED/94143818; Klopper JM; Myers JE; Ehrlich R; McIntyre D; Chetty K; Weir G; Hoffman M; Cooper D; London L
Traditional healers and AIDS prevention [letter; comment]: S Afr Med J. 1993 Sep;83(9):690-1. Unique Identifier : AIDSLINE MED/94143820; Swift PJ; Strang JI
Declining efficacy of AIDS case list cross-referencing in human immunodeficiency virus look-back: 1981 through 1992.: Transfusion. 1994 Feb;34(2):147-51. Unique Identifier : AIDSLINE MED/94143944; Samson SM; Edmiston RK; Busch MP; Perkins HA; Irwin Memorial Blood Centers, University of California, San; Francisco.; BACKGROUND: The impact of AIDS case list cross-referencing in human immunodeficiency virus look-back was assessed. STUDY DESIGN AND METHODS: Post-1977 blood donations from former donors identified by 11 collaborating health departments as having developed AIDS have been traced at Irwin Memorial Blood Centers since 198
Potential deferral criteria predictive of human immunodeficiency virus positivity among blood donors in Thailand [published erratum appears in Transfusion 1994 Apr;34(4):364]: Transfusion. 1994 Feb;34(2):152-7. Unique Identifier : AIDSLINE MED/94143945; Kitayaporn D; Bejrachandra S; Chongkolwatana V; Chandanayingyong D; Weniger BG; HIV/AIDS Collaboration, Nonthaburi, Thailand.; BACKGROUND: To develop deferral criteria to prevent human immunodeficiency virus (HIV) transmission by recently infected blood donors in the seronegative window phase, routine data on donors at a university hospital were examined for factors predicting seropositivity. STUDY DESIGN AND METHODS: Records of all 281 HIV-p
Human T-lymphotropic virus type II in Panamanian Guaymi Indians.: Transfusion. 1994 Feb;34(2):158-61. Unique Identifier : AIDSLINE MED/94143946; Feigenbaum F; Fang C; Sandler SG; Georgetown University Medical Center, Washington, D.C.; BACKGROUND: Currently, human T-lymphotropic virus type II (HTLV-II) is the most prevalent human retrovirus, detected in persons presenting to donate blood in the United States . Only scant information is available with which to counsel HTLV-II-seropositive deferred donors or other perso
HTLV-I and HTLV-II infections in French blood donors [letter; comment]: Vox Sang. 1993;65(4):334. Unique Identifier : AIDSLINE MED/94144174; Courouce AM; Pillonel J; Lemaire JM
Hepatitis B vaccination in prisons: the Catalonian experience.: Vaccine. 1993 Nov;11(14):1441-4. Unique Identifier : AIDSLINE MED/94144255; Bayas JM; Bruguera M; Martin V; Vidal J; Rodes J; Salleras LY; Servicio de Medicina Preventiva, Hospital Clinic i Provincial,; Barcelona, Spain.; A pilot programme of hepatitis B vaccination was set up in three prisons to assess the feasibility and results of this method of reaching a high-risk population. Hepatitis B vaccine was offered to all inmates who lacked serological markers for hepatitis B virus. The antibody response was assessed in those who received
Acute varicella-zoster virus ventriculitis and meningo-myelo-radiculitis in acquired immunodeficiency syndrome.: Acta Neuropathol (Berl). 1993;86(6):659-65. Unique Identifier : AIDSLINE MED/94144349; Chretien F; Gray F; Lescs MC; Geny C; Dubreuil-Lemaire ML; Ricolfi F; Baudrimont M; Levy Y; Sobel A; Vinters HV; Department de Pathologie (Neuropathologie), Hopital Henri; Mondor, Faculte de Medecine de Creteil, Universite Paris XII,; France.; A 30-year-old AIDS patient with no history of cutaneous eruption, presented with rapidly progressive flaccid paraplegia, hypoesthesia, urinary retention, moderate psychomotor slowing and fever (39.8 degrees C), leading to death within 1 week. CD4 count was 290/mm3. Cerebrospinal fluid contained 210 white blood cells a
Gastrointestinal manifestations of AIDS in children.: AJR Am J Roentgenol. 1994 Feb;162(2):387-93. Unique Identifier : AIDSLINE MED/94144485; Haller JO; Cohen HL; Department of Radiology, State University of New York Health; Science Center, Downstate Medical Center, Brooklyn 11203.; The gastrointestinal manifestations of AIDS in children are related to opportunistic infections, lymphoproliferative disease, and cancer. The infections that affect the gastrointestinal tract at different sites also occur in patients without AIDS. However, in children with AIDS, the infections are more severe, often r
The high risk autopsy. Recognition and protection.: Am J Forensic Med Pathol. 1993 Sep;14(3):253-6. Unique Identifier : AIDSLINE MED/94144622; Claydon SM; Institute of Forensic Medicine, University of Wales College of; Medicine, Cardiff.; The high-risk autopsy is defined as postmortem examination of a deceased person who has had, or is likely to have had, a serious infectious disease that can be transmitted to those present at the autopsy, thereby causing them serious illness and/or premature death. In this article, particular attention is paid to huma
Role of human immunodeficiency virus infection in the pathogenesis of human papillomavirus-associated cervical neoplasia.: Am J Pathol. 1994 Feb;144(2):209-14. Unique Identifier : AIDSLINE MED/94144670; Braun L; Department of Pathology and Laboratory Medicine, Brown; University, Providence, RI 02912.; Although many basic questions about the relationship between HIV and HPV infection remain unresolved, epidemiological studies have consistently shown a strong association between HIV infection and the development of HPV-related squamous intraepithelial neoplasia. This work indicates that HIV infection may promote the
Household epidemiology of Cryptosporidium parvum infection in an urban community in northeast Brazil [see comments]: Ann Intern Med. 1994 Mar 15;120(6):500-5. Unique Identifier : AIDSLINE MED/94144982; Newman RD; Zu SX; Wuhib T; Lima AA; Guerrant RL; Sears CL; Johns Hopkins University School of Medicine, Baltimore, Maryland.; OBJECTIVE: To examine the transmission of Cryptosporidium infection in households with an identified person with cryptosporidiosis. DESIGN: Prospective cohort study. SETTING: An urban slum in Fortaleza, Brazil . PARTICIPANTS: Thirty-one households with a child less than 3 years of a
Nursing's response to the crisis of access, costs, and quality in health care.: ANS Adv Nurs Sci. 1993 Sep;16(1):1-20. Unique Identifier : AIDSLINE MED/94145044; Schroeder C; Denver Nursing Project in Human Caring, CO.; Changes now taking place in the structure of health care delivery in the United States from regulatory models controlled by physicians to competitive models driven by traditional market forces of cost and quality are beginning to open opportunities for innovative nursing practice model
Accumulation and metabolism of adenallene by murine leukemia L1210 cells.: Arch Biochem Biophys. 1994 Jan;308(1):222-5. Unique Identifier : AIDSLINE MED/94145083; Kessel D; Zemlicka J; Department of Pharmacology and Medicine, Wayne State University,; Detroit, Michigan 48201.; Accumulation of the anti-HIV agent adenallene was examined in murine leukemia L1210 cells. Initial studies indicated an unusual result: accumulation of labeled adenallene was enhanced by decreasing the temperature of incubation, and (at 37 degrees C) by extracellular adenine, but not adenosine, cytosine, or thymine. W
Treatment of patients with polyarthritis and anti-HTLV-I antibodies with interferon-alpha [letter]: Ann Rheum Dis. 1994 Jan;53(1):80-1. Unique Identifier : AIDSLINE MED/94145195; Aoyagi T; Maeda K; Furuichi I; Eguchi K; Sakai M; Nagataki S; Iwasaki K
Granulomatous peritoneal cryptococcomas. An unusual sequela of disseminated cryptococcosis.: Arch Pathol Lab Med. 1994 Feb;118(2):194-5. Unique Identifier : AIDSLINE MED/94145304; Gordon SM; Gal AA; Amerson JR; Department of Medicine, Emory University School of Medicine,; Atlanta, Ga.; We report an unusual case of fibrosing peritoneal cryptococcal granulomas in a 36-year-old human immunodeficiency virus-negative man with small-bowel obstruction who previously had been treated for cryptococcal meningitis. At laparotomy, multiple pinhead-sized granulomas studded the visceral peritoneum. Microscopic ex
Acquired immunodeficiency syndrome-related primary central nervous system lymphoma.: Arch Ophthalmol. 1994 Feb;112(2):269-71. Unique Identifier : AIDSLINE MED/94145425; Maclean H; Ironside J; Dhillon B
[Ultrastructural study of azidothymidine-induced melanoderma in an AIDS patient]: Ann Pathol. 1993;13(5):328-31. Unique Identifier : AIDSLINE MED/94145506; Hermanns-Le T; Gerardy-Goffin F; Giet-Lesuisse M; Pierard GE; Service de Dermatopathologie, CHU du Sart Tilman, Universite de; Liege.; We report an ultrastructural study of azidothymidine-induced melanoderma. The hyperpigmentation is linked to the presence of numerous single melanosomes and polymelanosomes in keratinocytes at all levels of the epidermis, and in dermal Factor XIIIa-positive dendrocytes. Such observation suggests an increased melanogen
[Bacillary peliosis in AIDS. Anatomo-clinical study of 2 cases]: Ann Pathol. 1993;13(5):341-5. Unique Identifier : AIDSLINE MED/94145509; Mainguene C; Moreau A; Hofman P; Milpied-Homsi B; Roulot D; Marullo S; Clauvel JP; Lenne Y; Amouroux J; Service d'Anatomie Pathologique, Hopital Avicenne, Bobigny.; The authors report two cases of peliosis hepatis, occurring in patients with AIDS, who presented a persistent fever and an hepatomegaly. The liver biopsies showed areas of peliosis, where bacilli were observed by Warthin-Starry stain. In one case, techniques of molecular biology allowed the identification of Rochalima
Magnetic resonance imaging of intracranial fungal infections.: Top Magn Reson Imaging. 1994 Winter;6(1):22-31. Unique Identifier : AIDSLINE MED/94145636; Ostrow TD; Hudgins PA; Department of Radiology, School of Medicine, Emory University; Hospital, Atlanta, Georgia 30322.; Intracranial fungal infections have increased in incidence in the past decade caused in part by the acquired immunodeficiency syndrome (AIDS) epidemic. The biology, epidemiology, and appearance on computed tomography (CT) and magnetic resonance imaging (MRI) of the more common fungal infections of the central nervous
Brain infections in human immunodeficiency virus positive patients.: Top Magn Reson Imaging. 1994 Winter;6(1):3-10. Unique Identifier : AIDSLINE MED/94145637; Castillo M; Neuroradiology Section, University of North Carolina Medical; School, Chapel Hill 27599-7510.; This review discusses the magnetic resonance imaging (MRI) features of direct human immunodeficiency virus (HIV) brain infection as well as other common opportunistic infections and neoplasms in the acquired immunodeficiency syndrome (AIDS) population. MRI utilizing T2-weighted images is an ideal method for screening.
Practice nurses: characteristics, workload and training needs.: Br J Gen Pract. 1994 Jan;44(378):15-8. Unique Identifier : AIDSLINE MED/94145721; Ross FM; Bower PJ; Sibbald BS; Division of General Practice, St George's Hospital Medical; School, London.; AIM. This study set out to identify the present and future training needs of practice nurses in South West Thames Regional Health Authority and to examine these needs within the nurses current and changing workloads and social, educational and occupational profiles. METHOD. A questionnaire was sent to 899 practice st
A synthetic peptide from HIV-1 gp41 is a potent inhibitor of virus-mediated cell-cell fusion [letter]: AIDS Res Hum Retroviruses. 1993 Nov;9(11):1051-3. Unique Identifier : AIDSLINE MED/94145737; Wild C; Greenwell T; Matthews T
Inhibition of tat-activated, HIV-1 long terminal repeat-mediated gene expression by glucocorticoids [letter; comment]: AIDS Res Hum Retroviruses. 1993 Nov;9(11):1055-6. Unique Identifier : AIDSLINE MED/94145738; Mitra D; Sikder S; Laurence J
Identification of a calmodulin-binding and inhibitory peptide domain in the HIV-1 transmembrane glycoprotein.: AIDS Res Hum Retroviruses. 1993 Nov;9(11):1057-66. Unique Identifier : AIDSLINE MED/94145739; Miller MA; Mietzner TA; Cloyd MW; Robey WG; Montelaro RC; Department of Molecular Genetics and Biochemistry, University of; Pittsburgh School of Medicine, Pennsylvania 15261.; A number of studies suggest a critical role of the HIV-1 envelope glycoprotein in cytopathogenesis, but the detailed mechanisms of cell injury remain to be defined. HIV-1 envelope proteins associate with the host cell membrane, and studies have demonstrated that HIV perturbs membrane structure and function. We describ
CD8+ T lymphocyte-mediated inhibition of HIV-1 long terminal repeat transcription: a novel antiviral mechanism.: AIDS Res Hum Retroviruses. 1993 Nov;9(11):1079-86. Unique Identifier : AIDSLINE MED/94145741; Chen CH; Weinhold KJ; Bartlett JA; Bolognesi DP; Greenberg ML; Department of Surgery, Duke University Medical Center, Durham,; North Carolina 27710.; HIV-1 infection evokes a vigorous antiviral response that may participate in resolving the initial peak of plasma viremia and maintenance of the asymptomatic state. CD8+ T lymphocytes of HIV-1-infected individuals play a critical role in the cellular anti-HIV response. In agreement with previous reports, we observed a
Inhibition of entry of HIV into cells by poly(A).poly(U).: AIDS Res Hum Retroviruses. 1993 Nov;9(11):1087-90. Unique Identifier : AIDSLINE MED/94145742; Krust B; Callebaut C; Hovanessian AG; Unite de Virologie et Immunologie Cellulaire, Unite 1157 CNRS,; Institut Pasteur, Paris, France.; Polyadenylic-polyuridylic acid referred to as poly(A).poly(U), is a synthetic double-stranded RNA that has been shown to manifest both antitumoral and immunodulatory activities. Previously, we have reported that poly(A).poly(U) inhibits HIV infection in cell cultures. Here we provide direct evidence to demonstrate tha
Continuous presence of CD4-PE40 is required for antiviral activity against single-passage HIV isolates and infected peripheral blood mononuclear cells.: AIDS Res Hum Retroviruses. 1993 Nov;9(11):1091-6. Unique Identifier : AIDSLINE MED/94145743; Winters MA; Merigan TC; Center for AIDS Research, Stanford University Medical Center,; California 94305.; CD4-PE40, a recombinant protein consisting of a portion of human CD4 linked to Pseudomonas aeruginosa exotoxin, was studied in vitro to assess its ability to inhibit the replication of primary isolates of HIV. CD4-PE40 was added to cultures of phytohemagglutin (PHA)-stimulated normal peripheral blood mononuclear cells
Increased efficacy of human natural interferon alpha (IFN-alpha n3) versus human recombinant IFN-alpha 2 for inhibition of HIV-1 replication in primary human monocytes.: AIDS Res Hum Retroviruses. 1993 Nov;9(11):1115-22. Unique Identifier : AIDSLINE MED/94145746; Fan SX; Skillman DR; Liao MJ; Testa D; Meltzer MS; Department of Cellular Immunology, Walter Reed Army Institute of; Research, Washington, D.C. 20307-5100.; Natural IFN-alpha n3, a purified mixture of many different natural IFN alpha species, was 10- to 100-fold more effective than equal concentrations of human rIFN-alpha 2b or rIFN-alpha 2a for inhibition of HIV replication in primary human monocytes. This difference was highly reproducible in multiple side-by-side exper
Association of interleukin-6 in the pathogenesis of acutely fatal SIVsmm/PBj-14 in pigtailed macaques.: AIDS Res Hum Retroviruses. 1993 Nov;9(11):1123-9. Unique Identifier : AIDSLINE MED/94145747; Birx DL; Lewis MG; Vahey M; Tencer K; Zack PM; Brown CR; Jahrling PB; Tosato G; Burke D; Redfield R; Department of Retroviral Research, Walter Reed Army Institute of; Research, Rockville, Maryland 20850.; Infection with a variant of simian immunodeficiency virus (SIVsmm/PBj-14) causes death in juvenile pigtailed macaques within 8 days of infection. The primary pathology is localized to the lymphoid tissues of the gut and spleen. Although the virus is present, the lesions are most consistent with acute reactive inflamma
In vitro spontaneous production of anti-SIV antibodies is a reliable tool in the follow-up of protection of SIV-vaccinated monkeys.: AIDS Res Hum Retroviruses. 1993 Nov;9(11):1139-44. Unique Identifier : AIDSLINE MED/94145749; Zamarchi R; Veronese ML; Titti F; Geraci A; Verani P; Rossi GB; Amadori A; Chieco-Bianchi L; Institute of Oncology, University of Padova, Padua, Italy.; To assess the reliability of the spontaneous in vitro synthesis of simian immunodeficiency virus (SIV)-specific antibodies as a marker in the monitoring of protection in SIV-vaccinated animals, Macaca fascicularis monkeys were immunized with formalin-inactivated SIVmac251 or SIVmac251/32H, and challenged with human-de
The amino-terminal peptide of HIV-1 gp41 interacts with human serum albumin.: AIDS Res Hum Retroviruses. 1993 Nov;9(11):1145-56. Unique Identifier : AIDSLINE MED/94145750; Gordon LM; Curtain CC; McCloyn V; Kirkpatrick A; Mobley PW; Waring AJ; Department of Pediatrics, Drew University, King Medical; Center/UCLA 90059.; Structural and functional studies were made to assess interactions between human serum albumin (HSA) and the amino-terminal peptide (FP-I; 23-residue peptide 519-541) of glycoprotein 41,000 (gp41) of human immunodeficiency virus type-1 (HIV-1). Circular dichroism (CD) spectroscopy indicated that the peptide binds to a
Association of host cell surface adhesion receptors and other membrane proteins with HIV and SIV.: AIDS Res Hum Retroviruses. 1993 Nov;9(11):1157-65. Unique Identifier : AIDSLINE MED/94145751; Orentas RJ; Hildreth JE; Department of Pharmacology and Molecular Sciences, Johns Hopkins; University School of Medicine, Baltimore, Maryland 21205.; We have developed a MAb-based capture assay to study the association of host cell membrane proteins with HIV and SIV. Class I and II MHC proteins were found to be associated with HIV as previously described. In addition to these molecules a number of other host molecules were found to be acquired by HIV, including CD7
Unintegrated two-long terminal repeat circular human T lymphotropic virus DNA accumulation during chronic HTLV infection.: AIDS Res Hum Retroviruses. 1993 Nov;9(11):1167-72. Unique Identifier : AIDSLINE MED/94145752; Kitamura K; Besansky NJ; Rudolph D; Nutman TB; Folks TM; Lal RB; Retrovirus Diseases Branch, Centers for Disease Control and; Prevention, Atlanta, Georgia 30333.; Accumulation of unintegrated human T lymphotropic virus (HTLV) DNA was analyzed in long-term T cell lines infected with HTLV type I (HTLV-I) or type II (HTLV-II). By using a polymerase chain reaction-based assay, amplified products of expected size were obtained in all of the HTLV-I-infected (n = 7) and HTLV-II-infect
Living each moment.: Am J Hosp Palliat Care. 1993 May-Jun;10(3):33-5. Unique Identifier : AIDSLINE MED/94145782; Cooke MA
[Needlestick injuries (interview by Marit Fonn)]: J Sykepleien. 1993 Aug 10;81(12):12-3. Unique Identifier : AIDSLINE MED/94145787; Botnan R
[USA: tuberculosis rampant in New York (news) (published erratum appears in J Sykepleien 1993 Sep 7;81(14):21)]: J Sykepleien. 1993 Aug 10;81(12):21. Unique Identifier : AIDSLINE MED/94145792
[Insane and completely happy (interview by Siv Barstad)]: J Sykepleien. 1993 Aug 10;81(12):24-5. Unique Identifier : AIDSLINE MED/94145793; Bodahl E
Hematopoietic growth factors in cancer chemotherapy.: Cancer Chemother Biol Response Modif. 1993;14:353-70. Unique Identifier : AIDSLINE MED/94145815; Morstyn G; Sheridan WP; Medical and Clinical Affairs, AMGEN Center, Thousand Oaks, CA.
Therapy of sporotrichosis.: Semin Dermatol. 1993 Dec;12(4):285-9. Unique Identifier : AIDSLINE MED/94145860; Mercurio MG; Elewski BE; Department of Dermatology, University Hospitals of Cleveland,; Case Western Reserve University, OH 44106.; Sporotrichosis is a fungal infection caused by the dimorphic organism, Sporothrix schenkii. This etiologic agent typically gains entrance into the skin by traumatic implantation of infected soil or plant materials. The majority of cases are of the fixed cutaneous or lymphangitic cutaneous varieties, and less commonly,
Coccidioidomycosis.: Semin Dermatol. 1993 Dec;12(4):301-9. Unique Identifier : AIDSLINE MED/94145863; Pappagianis D; Department of Medical Microbiology and Immunology, School of; Medicine, University of California, Davis 95616.; Coccidioidomycosis is usually acquired by inhalation of Coccidioides immitis in certain areas of the Western Hemisphere. However, the disease may occur far away in individuals who have visited or lived in, then departed from, the endemic areas. The disease which can affect normal and immunocompromised individuals, has
Histoplasmosis.: Semin Dermatol. 1993 Dec;12(4):310-4. Unique Identifier : AIDSLINE MED/94145864; Hay RJ; St John's Institute of Dermatology, Guys Hospital, London, UK.; Histoplasmosis is an infection caused by the dimorphic fungus, Histoplasma capsulatum. The initial site of entry is usually the lung, but dissemination to skin occurs in some patients, particularly those with human immunodeficiency virus (HIV) infection in whom it is part of a widespread infection. The organisms have
Advances in the treatment of superficial candida infections.: Semin Dermatol. 1993 Dec;12(4):315-30. Unique Identifier : AIDSLINE MED/94145865; Goldstein SM; Department of Dermatology, University of California, San; Francisco 94143-0536.; This article reviews recent controlled studies of treatment for candida infections of the skin and mucous membranes. In general, excellent agents are available for treatment, with reasonable alternatives for the uncommon emergence of resistant strains. Cutaneous infections in immunocompetent patients are effectively t
Nurse sues after HIV accident infection [news]: Nurs Stand. 1993 Dec 8-14;8(12):6. Unique Identifier : AIDSLINE MED/94145886
UKCC. Behind closed doors.: Nurs Stand. 1994 Jan 12-18;8(16):22-3. Unique Identifier : AIDSLINE MED/94145902; Pink G
AIDS focus. Caring for the family hit by HIV.: Nurs Stand. 1994 Jan 12-18;8(16):48-9. Unique Identifier : AIDSLINE MED/94145910; Ayub A
AIDS focus. HIV and the long-term mentally ill.: Nurs Stand. 1994 Jan 12-18;8(16):50-3. Unique Identifier : AIDSLINE MED/94145911; Walker S; Fraiser D
AIDS focus. What's on.: Nurs Stand. 1994 Jan 12-18;8(16):54. Unique Identifier : AIDSLINE MED/94145912; Alderman C
Fears of HIV spread as agency loses health board funding [news]: Nurs Stand. 1994 Jan 12-18;8(16):7. Unique Identifier : AIDSLINE MED/94145913
HIV seropositive cases presenting as urological patients at the Korle-Bu Teaching Hospital, Accra--a preliminary report.: West Afr J Med. 1993 Jul-Sep;12(3):158-61. Unique Identifier : AIDSLINE MED/94145932; Yeboah ED; Neequaye AR; Mingle JA; Asamoah-Adu A; Department of Surgery, Medicine and Therapeutics, Ghana Medical; School, Korle Bu Teaching Hospital, Accra.; Thirty-six patients (33 males, 3 females) were screened for HIV antibodies at the Urological clinics, at the Korle Bu Teaching Hospital, Accra because of chronic diarrhoea, unexplained weight loss, multiple sexual partners, recurrent sexually transmitted diseases, non resolution of symptoms or history of possible expo
Structure of the VH and VL segments of polyreactive and monoreactive human natural antibodies to HIV-1 and Escherichia coli beta-galactosidase.: Int Immunol. 1993 Dec;5(12):1523-33. Unique Identifier : AIDSLINE GENBANK/L25298; Harindranath N; Ikematsu H; Notkins AL; Casali P; Laboratory of Oral Medicine, National Institute of Dental; Research, National Institutes of Health, Bethesda, MD 20892.; B lymphocytes committed to the production of antibodies binding to antigens on pathogenic bacteria and viruses (natural antibodies) are common components of the normal human B cell repertoire. A major proportion of natural antibodies is capable of binding multiple antigens (polyreactive antibodies). Using B cells from
An evaluation of an AIDS risk reduction education and skills training (ARREST) program.: J Adolesc Health. 1993 Nov;14(7):533-9. Unique Identifier : AIDSLINE MED/94146024; Kipke MD; Boyer C; Hein K; Adolescent AIDS Program, Montefiore Medical Center/Albert; Einstein College of Medicine, Los Angeles, California.; PURPOSE. With the increasing rate of HIV infection among adolescents, there is an urgent need for interventions that will provide teenagers with information, the ability to make decisions, and the assertiveness and communication skills required for effective prevention and risk reduction. This study evaluated an AIDS
Condom availability in schools.: J Adolesc Health. 1993 Nov;14(7):565-8. Unique Identifier : AIDSLINE MED/94146030; Blair J
A monoclonal antibody directed to sulfatide inhibits the binding of human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein to macrophages but not their infection by the virus.: Biochim Biophys Acta. 1994 Feb 22;1225(3):289-96. Unique Identifier : AIDSLINE MED/94146129; Seddiki N; Ramdani A; Saffar L; Portoukalian J; Gluckman JC; Gattegno L; Laboratoire de Biologie Cellulaire, Faculte de Medecine; Paris-Nord, Bobigny, France.; We show here that human immunodeficiency virus (HIV) envelope glycoproteins (gp160/gp120) bind to sulfatide and galactosyl ceramide. By immunofluorescence labeling with monoclonal antibody (mAb) A2B5, specific for ganglioside/sulfatide, we detect negatively charged glycolipids on CD4+ cells of the macrophage lineage a
Diseases among men living in human T-lymphotropic virus type I endemic areas in Japan.: Intern Med. 1993 Aug;32(8):623-8. Unique Identifier : AIDSLINE MED/94146465; Matsuzaki T; Otose H; Hashimoto K; Shibata Y; Arimura K; Osame M; Third Department of Internal Medicine, Faculty of Medicine,; Kagoshima University, Japan.; The health effects of human T-lymphotropic virus type I (HTLV-I) were studied in HTLV-I endemic areas in Japan during the period from September 1990 to October 1991. The study subjects were 2,847 men living in the southern part of Kyushu and engaged in light work. Ages ranged from 1
Incidence of HIV-1 infection in a rural region of Uganda [see comments]: BMJ. 1994 Jan 15;308(6922):171-3. Unique Identifier : AIDSLINE MED/94146627; Wawer MJ; Sewankambo NK; Berkley S; Serwadda D; Musgrave SD; Gray RH; Musagara M; Stallings RY; Konde-Lule JK; Center for Population and Family Health, Columbia University; School of Public Health, New York, NY 10032.; OBJECTIVE--To determine the incidence of infection with HIV-1 and the risk factors associated with seroconversion in three geographical strata of a rural Ugandan district. DESIGN--Serological, sociodemographic, and behavioural surveys of everyone aged 13 or more in 21 randomly selected communities at baseline and one
Cytomegalovirus retinitis under combination therapy with zidovudine and dideoxycytidine in advanced human immunodeficiency virus infection.: Ger J Ophthalmol. 1993 Nov;2(6):412-5. Unique Identifier : AIDSLINE MED/94146693; Kaulen P; Pham DT; Baranowski E; Wollensak J; Department of Ophthalmology, Klinikum Rudolf Virchow, Freie; Universitat, Berlin, Germany.; The incidence of cytomegalovirus ( CMV ) retinitis during combination therapy with zidovudine (azidothymidine AZT
HIV/AIDS-related knowledge, attitudes, and practices among Managuan secondary school students.: Bull Pan Am Health Organ. 1993;27(4):360-9. Unique Identifier : AIDSLINE MED/94146855; Egger M; Ferrie J; Gorter A; Gonzalez S; Gutierrez R; Pauw J; Smith GD; Department of Social and Preventive Medicine, University of Bern,; Switzerland.; In 1990, the AIDS-related knowledge, attitudes, and practices of fifth year (final year) students at four Managuan high schools were assessed. This was done by means of a self-administered questionnaire completed by 451 students (155 males, 296 females) whose mean age was 18 years. Eighty-six percent of the subjects k
Oligonucleotide-enzyme conjugates.: Methods Mol Biol. 1994;26:167-85. Unique Identifier : AIDSLINE MED/94146912; Ruth JL; US Fish and Wildlife Forensics Laboratory, Ashland, OR.
[Basic ethical rules for the care of HIV positive patients and patients with AIDS]: Pflege Aktuell. 1993 Dec;47(12):712. Unique Identifier : AIDSLINE MED/94147012
AIDS survey shows limited knowledge [news]: J Nurs Manag. 1993 Sep;1(5):261. Unique Identifier : AIDSLINE MED/94147041
Interleukin 1 beta inhibits synaptic strength and long-term potentiation in the rat CA1 hippocampus.: Brain Res. 1993 Nov 19;628(1-2):227-34. Unique Identifier : AIDSLINE MED/94147137; Bellinger FP; Madamba S; Siggins GR; Department of Neuropharmacology, Scripps Research Institute, La; Jolla, CA 92037.; Cytokines such as interleukin-1 beta (IL-1 beta) are released in the nervous system following inflammation or infection. Recently, IL-1 beta was shown to enhance synaptic inhibitory mechanisms. We therefore investigated the effect of IL-1 beta superfusion on long-term potentiation (LTP), the cellular model of memory a
HTLV-I associated myelopathy: an endemic disease of Canadian aboriginals of the Northwest Pacific coast?: Can J Neurol Sci. 1993 Nov;20(4):302-6. Unique Identifier : AIDSLINE MED/94147254; Oger JJ; Werker DH; Foti DJ; Dekaban GA; Department of Medicine, University of British Columbia,; Vancouver.; Human T-cell lymphotropic virus type 1 (HTLV-I) is responsible for HTLV-I associated myelopathy or tropical spastic paraparesis (HAM/TSP) and for adult T-cell leukemia/lymphoma (ATLL). Both diseases have been well described in individuals living in Japan , West Indies,
Revision of the surveillance case definition for AIDS in Canada.: Can Med Assoc J. 1994 Feb 15;150(4):531-4. Unique Identifier : AIDSLINE MED/94147278
Cervicovaginal screening in women with HIV infection: a need for increased vigilance?: Can Med Assoc J. 1994 Mar 1;150(5):681-6. Unique Identifier : AIDSLINE MED/94147302; Hankins CA; Lamont JA; Handley MA; Centre for AIDS Studies, Montreal Regional Public Health Team,; Public Health Unit, Montreal General Hospital, PQ.; OBJECTIVE: To review the current literature on cervical disease (dysplasia, cervical intraepithelial neoplasia [CIN] or carcinoma) in women with HIV infection and to assess recommendations for cervicovaginal screening in these patients. DATA SOURCES: MEDLINE and AIDSLINE were searched for relevant articles published i
Impact of HIV infection and AIDS on death rates in British Columbia and Canada.: Can Med Assoc J. 1994 Mar 1;150(5):711-7. Unique Identifier : AIDSLINE MED/94147305; Hogg RS; Schechter MT; Montaner JS; Goldstone I; Craib K; O'Shaughnessy MV; British Columbia Centre for Excellence in HIV/AIDS, St. Paul's; Hospital, Vancouver.; OBJECTIVE: To assess the impact of HIV infection and AIDS on death rates in British Columbia and Canada . DESIGN: Descriptive, population-based study. SETTING: British Columbia and Canada. PATIENTS: All people for whom HIV infection or AIDS was listed as the underlying cause of deat
Syphilis-associated perinatal and infant mortality in rural Malawi.: Bull World Health Organ. 1993;71(6):773-80. Unique Identifier : AIDSLINE MED/94147532; McDermott J; Steketee R; Larsen S; Wirima J; Epidemiologist, Malaria Branch, Centers for Disease Control and; Prevention, Atlanta, GA 30333.; In Mangochi District, a rural area of Malawi , the prevalence of active syphilis was 3.6% among 3591 women who had singleton births and who were negative for human immunodeficiency virus (HIV). Compared with non-syphilitic women, those with active syphilis (positive Venereal Disease
Solid-phase extraction combined with radioimmunoassay for measurement of zalcitabine (2',3'-dideoxycytidine) in plasma and serum.: Clin Chem. 1994 Feb;40(2):211-5. Unique Identifier : AIDSLINE MED/94147642; Roberts WL; Buckley TJ; Rainey PM; Jatlow PI; Department of Laboratory Medicine, Yale University School of; Medicine, New Haven, CT 06510.; Of the antiviral agents that are currently in clinical use in the US for therapy for human immunodeficiency virus infections, zalcitabine ( ddC ) is the most potent and is effective at the lowest plasma concentrations. The two reported procedures for me
Autoimmune blistering diseases associated with HIV infection.: Clin Exp Dermatol. 1994 Jan;19(1):47-50. Unique Identifier : AIDSLINE MED/94147694; Bull RH; Fallowfield ME; Marsden RA; Department of Dermatology, St George's Hospital, London, UK.; Two cases of autoimmune bullous skin diseases in HIV-positive men are described. One man had bullous pemphigoid limited to his legs and the second man developed pemphigus herpetiformis. The possible association between autoimmune bullous diseases and HIV infection is discussed.
Lichen scrofulosorum in a patient with AIDS.: Clin Exp Dermatol. 1994 Jan;19(1):74-6. Unique Identifier : AIDSLINE MED/94147703; Arianayagam AV; Ash S; Jones RR; Department of Dermatology, Ealing Hospital National Health Trust,; Southall, Middlesex, UK.; A patient with AIDs who presented with pulmonary tuberculosis and cervical scrofuloderma developed a widespread eruption of lichenoid papules shortly after commencing antituberculous therapy. The clinical and histological features in this case were consistent with lichen scrofulosorum even though the tuberculin test w
Analysis of natural killer (NK) cell subsets defined by the expression of two novel surface antigens (EB6 and GL183) in AIDS and AIDS-related conditions.: Clin Immunol Immunopathol. 1994 Mar;70(3):198-205. Unique Identifier : AIDSLINE MED/94147715; Cauda R; Goletti D; Lucia MB; Tumbarello M; Rumi C; Orengo AM; Moretta A; Istituto di Clinica Malattie Infettive, Universita Cattolica S.; Cuore, Roma, Italy.; In this study we analyzed the expression of EB6 and GL183, which are part of P58 molecular family that represents the putative NK receptor for MHC class I molecules, in peripheral blood lymphocytes of 60 patients with HIV infection (20 asymptomatic HIV-seropositive individuals, 20 patients with constitutional symptoms
[Intravesical instillation of BCG for the bladder cancer: relationship between effect and immune cells in peripheral blood and bladder wall]: Chung Hua Wai Ko Tsa Chih. 1993 Jun;31(6):336-8. Unique Identifier : AIDSLINE MED/94147827; Chen LZ; First Affiliated Hospital of Sun Yat-sen University of Medical; Sciences, Guangzhou.; Immunohistochemical technique was used to investigate the immune cells both in the peripheral blood and the bladder wall of the bladder cancer patients before and after intravesical instillation of BCG. CD4+ and the ratio of CD4+/CD8+ in the responders were significantly higher than that in the nonresponders in periph
Comparison of two glucocorticoid preparations (deflazacort and prednisone) in the treatment of immune-mediated diseases.: Eur J Clin Pharmacol. 1993;45 Suppl 1:S29-34. Unique Identifier : AIDSLINE MED/94148037; Scudeletti M; Puppo F; Lanza L; Mantovani L; Bosco O; Iudice A; Imbimbo B; Indiveri F; Department of Internal Medicine, Clinical Methodology, University; of Genoa, Italy.; Different glucocorticoid preparations modify the immune reaction in different ways. In this paper, the therapeutic efficacy of two glucocorticoids, deflazacort (DFZ) and prednisone (PDN), are discussed in relation to a group of 30 patients with systemic lupus erythematosus (n = 12) or rheumatoid arthritis (n = 18). Th
Data from the National AIDS Behavioral Surveys. I. Sexual risk for human immunodeficiency virus infection among women in high-risk cities.: Fam Plann Perspect. 1993 Nov-Dec;25(6):252-6, 277. Unique Identifier : AIDSLINE MED/94148057; Grinstead OA; Faigeles B; Binson D; Eversley R; Department of Medicine, University of California, San Francisco.; Data from 3,482 women aged 18-49 living in 23 urban areas of the United States who participated in the 1990-1991 National AIDS Behavioral Surveys show that in the preceding year, approximately 15% engaged in sexual behavior that might expose them to the human immunodeficiency virus (HI
Data from the National AIDS Behavioral Surveys. II. Multiple sexual partners among Hispanics in high-risk cities.: Fam Plann Perspect. 1993 Nov-Dec;25(6):257-62. Unique Identifier : AIDSLINE MED/94148058; Sabogal F; Faigeles B; Catania JA; Department of Medicine, University of California, San Francisco.; Data from a random sample of 4,658 heterosexual Hispanics from 23 high-risk cities in the 1990-1991 National AIDS Behavioral Surveys reveal that 11% of Hispanics have had multiple partners in the past year-17% of men and 4% of women. The study shows a higher proportion of multiple sexual partners in the past year amon
Data from the National AIDS Behavioral Surveys. III. Multiple sexual partners among blacks in high-risk cities.: Fam Plann Perspect. 1993 Nov-Dec;25(6):263-7. Unique Identifier : AIDSLINE MED/94148059; Peterson JL; Catania JA; Dolcini MM; Faigeles B; Department of Medicine, University of California, San Francisco.; The National AIDS Behavioral Surveys collected data between June 1990 and February 1991 on the prevalence of multiple sex partners and condom use among 2, 166 blacks living in cities with a high prevalence of AIDS cases. Almost one-fifth (19%) of respondents report having had two or more partners in the year preceding
Data from the National AIDS Behavioral Surveys. IV. Multiple sexual partners among young adults in high-risk cities.: Fam Plann Perspect. 1993 Nov-Dec;25(6):268-72. Unique Identifier : AIDSLINE MED/94148060; Binson D; Dolcini MM; Pollack LM; Catania JA; Center for AIDS Prevention Studies, University of California, San; Francisco.; Among a sample of 1,334 urban heterosexuals aged 18-25 from the 1990-1991 National AIDS Behavioral Surveys, 24% report having had more than one sexual partner during the past year. Young men are more than twice as likely as young women, and unmarried respondents are eight times as likely as married respondents, to hav
Site-directed mutagenesis of the P2 residue of human antithrombin.: FEBS Lett. 1994 Feb 14;339(1-2):147-50. Unique Identifier : AIDSLINE MED/94148073; Sheffield WP; Blajchman MA; Canadian Red Cross Blood Services, McMaster University Medical; Centre, Hamilton, Ont., Canada.; Antithrombin (AT) is the principal inhibitor of thrombin in human plasma, and a member of the serine proteinase (serpin) family of proteins. Previously, we have described a point mutation in the human AT gene that converted amino acid 392 from glycine to aspartic acid which was associated with thrombotic disease in a
The correlation between HIV seropositivity, cervical dysplasia, and HPV subtypes 6/11, 16/18, 31/33/35.: Gynecol Oncol. 1994 Feb;52(2):161-4. Unique Identifier : AIDSLINE MED/94148273; Tweddel G; Heller P; Cunnane M; Multhaupt H; Roth K; Department of Obstetrics and Gynecology, Pennsylvania Hospital,; Philadelphia 19107.; Twenty-one human immunodeficiency virus (HIV) seropositive patients were studied to determine the prevalence of cervical dysplasia, the distribution of human papilloma virus (HPV) subtypes, and the utility of cytologic diagnosis in this population. The patients ranged in age from 18 to 41 years. HIV infection was diag
Necrotizing tubulo-interstitial nephritis induced by adenovirus in an AIDS patient.: Histopathology. 1993 Dec;23(6):588-90. Unique Identifier : AIDSLINE MED/94148409; Shintaku M; Nasu K; Ito M; Department of Pathology, Osaka Red Cross Hospital, Japan.
Kaposi's sarcoma presenting as acute appendicitis in an HIV-1 positive patient.: Histopathology. 1993 Dec;23(6):590-1. Unique Identifier : AIDSLINE MED/94148410; Chetty R; Slavin JL; Miller RA; Department of Anatomical Pathology, Royal Melbourne Hospital,; Australia.
Production of interleukin-1 alpha and interleukin-2 by separate, phenotypically different leukaemia and human T cell lymphotropic virus-1-transformed T cell clones.: Immunol Cell Biol. 1993 Dec;71 ( Pt 6):509-15. Unique Identifier : AIDSLINE MED/94148487; Holan V; Minowada J; Institute of Molecular Genetics, Academy of Sciences of the Czech; Republic, Prague.; The relationship between interleukin-1 (IL-1) and interleukin-2 ( IL-2 ) production and immunophenotype marker profiles was studied in a panel of 29 leukaemia and human T cell lymphotropic virus-1 (HTLV-1)-transformed T cell lines. Culture supernatants from six of the 29
The effect of ethnic differences on the pattern of HTLV-I-associated T-cell leukemia/lymphoma (HATL) in the United States.: Int J Cancer. 1994 Jan 15;56(2):177-81. Unique Identifier : AIDSLINE MED/94148509; Levine PH; Manns A; Jaffe ES; Colclough G; Cavallaro A; Reddy G; Blattner WA; National Cancer Institute, Bethesda, MD 20892.; Human T-cell lymphotropic virus Type I (HTLV-I) is the primary etiologic factor for adult T-cell leukemia/lymphoma (ATL). Although HTLV-I is endemic in Japan and the Caribbean islands, the reported clinical and epidemiologic features of ATL in these 2 parts of the world are quite di
Decreased reactivity to PPD among HTLV-I carriers in relation to virus and hematologic status.: Int J Cancer. 1994 Feb 1;56(3):337-40. Unique Identifier : AIDSLINE MED/94148536; Welles SL; Tachibana N; Okayama A; Shioiri S; Ishihara S; Murai K; Mueller NE; Department of Epidemiology, Harvard School of Public Health,; Boston, MA.; Data on human T-cell lymphotropic-virus-type-I (HTLV-I) status and hematology from 528 individuals were analyzed for associations with low reactivity to the purified protein derivative (PPD) of Mycobacterium tuberculosis recall antigen. Subjects were classified as HTLV-I carriers with abnormal lymphocytes (Ably), carr
Inhibition of human B-cell chronic lymphocytic leukemia by a monoclonal antibody in xenograft models.: Int J Cancer. 1994 Feb 1;56(3):439-45. Unique Identifier : AIDSLINE MED/94148555; Zhu Z; Ghose T; Hoskin D; Lee CL; Fernandez LA; Rowden G; Lee SH; Department of Pathology, Dalhousie University, Halifax, Nova; Scotia, Canada.; To establish xenograft models of human B-cell chronic lymphocytic leukemia (CLL), we inoculated 5 x 10(6) D10-1 cells, a subline of Epstein-Barr virus (EBV)-transformed human B-cell CLL with a marker chromosomal anomaly, into SCID or irradiated nude mice by the intravenous (i.v.) or intraperitoneal (i.p.) route. All i
p53 protein over-expression and p53 gene abnormalities in HIV-1-related non-Hodgkin's lymphomas.: Int J Cancer. 1994 Mar 1;56(5):662-7. Unique Identifier : AIDSLINE MED/94148568; De Re V; Carbone A; De Vita S; Gloghini A; Maestro R; Gasparotto D; Vukosavljevic T; Boiocchi M; Division of Experimental Oncology 1, Centro di Riferimento; Oncologico, Aviano, Italy.; Alteration of the p53 tumor-suppressor gene was studied in non-Hodgkin s lymphomas (NHLs) from HIV-1-infected patients. p53 protein was over-expressed in 10 out of the 45 (22%) cases analyzed, mainly clustering in the small-non-cleaved-cell (SNC) (5/19) and Ki-1+ anaplastic large-cell (ALC) (3/8) sub-types, according
The spectrum of HIV related skin diseases in an Irish population.: Ir Med J. 1993 Nov-Dec;86(6):188-90. Unique Identifier : AIDSLINE MED/94148649; Healy E; Meenan J; Mulcahy F; Barnes L; Department of Dermatology, St. James's Hospital, Dublin.; A prospective study was carried out between January 1988 and January 1990 in St. James s hospital, Dublin, which is the chief referral centre for the HIV population in Ireland . Patients were routinely referred from the genitourinary
Diagnosis, care and management of the pediatric HIV/AIDS patient in Arkansas.: J Ark Med Soc. 1993 Nov;90(6):258-61. Unique Identifier : AIDSLINE MED/94148743; Tucker NC; Schutze GE; Darville T; Jacobs RF; Arkansas Children's Hospital.
Interactions of substrates and inhibitors with a family of tethered HIV-1 and HIV-2 homo- and heterodimeric proteinases.: J Biol Chem. 1994 Feb 18;269(7):4787-93. Unique Identifier : AIDSLINE MED/94148922; Griffiths JT; Tomchak LA; Mills JS; Graves MC; Cook ND; Dunn BM; Kay J; Department of Biochemistry, University of Wales College of; Cardiff, United Kingdom.; Genes were constructed to encode single-chain tethered human immunodeficiency virus HIV-1/HIV-1 and HIV-2/HIV-2 homodimeric proteinases and two HIV-1/HIV-2 heterodimers which differed in the nature of the interface strands. All four constructs under the control of a heat-inducible promoter were expressed in E. coli an
The substrate specificity of Saccharomyces cerevisiae myristoyl-CoA: protein N-myristoyltransferase. Polar probes of the enzyme's myristoyl-CoA recognition site.: J Biol Chem. 1994 Feb 18;269(7):5346-57. Unique Identifier : AIDSLINE MED/94149002; Lu T; Li Q; Katoh A; Hernandez J; Duffin K; Jackson-Machelski E; Knoll LJ; Gokel GW; Gordon JI; Department of Molecular Biology and Pharmacology, Washington; University School of Medicine, St. Louis, Missouri 63110.; Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase (Nmt1p) is a monomeric enzyme that is essential for vegetative growth. Nmt1p catalyzes the co-translational transfer of myristate from CoA to the amino-terminal Gly of cellular proteins in an ordered Bi Bi reaction mechanism that initially involves
Size-exclusion chromatographic determination of dextran sulfate in rat serum.: J Chromatogr. 1993 Oct 22;620(1):137-42. Unique Identifier : AIDSLINE MED/94149088; Maderich AB; Sugita ET; Philadelphia College of Pharmacy and Science, PA 19104-4495.; A sensitive and selective method for the determination of dextran sulfate in rat serum has been developed. The analysis is suitable for quantitation of the drug and for monitoring molecular mass changes occurring during biotransformation. Dextran sulfate is resolved from higher molecular mass serum components by high-
Assessment of chemical disinfectants against human immunodeficiency virus: overcoming the problem of cytotoxicity and the evaluation of selected actives.: J Virol Methods. 1993 Dec 31;45(3):247-57. Unique Identifier : AIDSLINE MED/94149107; Gordon V; Parry S; Bellamy K; Osborne R; Department of Veterinary Pathology, Glasgow University Veterinary; School, UK.; The aim of this study was to develop a standardised technique for assessing the virucidal activity of commercial disinfectants against human immunodeficiency virus (HIV). In the absence of any model procedure for HIV a protocol based on German DVV guidelines was developed. A major difficulty associated with such studi
Polymerase chain reaction detection of human cytomegalovirus in over 2000 blood specimens correlated with virus isolation and related to urinary virus excretion.: J Virol Methods. 1993 Dec 31;45(3):259-76. Unique Identifier : AIDSLINE MED/94149108; Drouet E; Michelson S; Denoyel G; Colimon R; Department of Infectiology, Institut Pasteur, Lyon, France.; The polymerase chain reaction (PCR) as applied to human cytomegalovirus (HCMV) detection should provide a valuable tool for rapid, reliable diagnosis of infection, thereby allowing prompt treatment. However, to date the high sensitivity of this technique and the lack of semi-quanti
Computer network for a diagnostic virology laboratory.: J Virol Methods. 1993 Dec 31;45(3):277-89. Unique Identifier : AIDSLINE MED/94149109; Stokes KJ; Morris DJ; Klapper PE; Semple AD; Crosdale E; Corbitt G; North Manchester Virus Laboratory, Booth Hall Children's; Hospital, Manchester, UK.; A data base for a large diagnostic virology laboratory is described. The system uses a network of personal computers. It allows the entry, long-term storage, and subsequent retrieval of specimen and patient records (comprising personal identifiers and specimen and result information), and hard-copy results reporting.
Neonatal treatment with luteinizing hormone-releasing hormone analogs alters peripheral lymphocyte subsets and cellular and humorally mediated immune responses in juvenile and adult male monkeys.: J Clin Endocrinol Metab. 1994 Feb;78(2):292-8. Unique Identifier : AIDSLINE MED/94149125; Mann DR; Ansari AA; Akinbami MA; Wallen K; Gould KG; McClure HM; Morehouse School of Medicine, Emory University School of; Medicine, Atlanta, Georgia 30310.; We examined the effect of treatment with a LH-releasing hormone (LHRH) agonist (Ag), antagonist (Ant), or Ant and androgen (Ant/And) for the first 4 months of postnatal life on lymphocyte subsets and cellular and humorally mediated immune responses in juvenile and adult male monkeys. We also determined the effect of 9
Preventing AIDS: knowledge, attitudes, and practices.: J Gerontol Nurs. 1994 Feb;20(2):21-8. Unique Identifier : AIDSLINE MED/94149249; Lewis J; Doyle K; Roemer L; 1. Because health care providers are the key professionals in advising patients about prevention and treatment of HIV/AIDS, the degree to which spread can be prevented is at least partially a function of preventive and education measures taken by health care professionals. 2. Nurses surveyed believe that they do not h
Sexually transmitted diseases and human immunodeficiency virus. Epidemiologic synergy?: Infect Dis Clin North Am. 1993 Dec;7(4):753-70. Unique Identifier : AIDSLINE MED/94149262; Clottey C; Dallabetta G; AIDS Control and Prevention Project (AIDSCAP), Family Health; International, Arlington, Virginia.; HIV infection and STDs are linked by common high risk behaviors. There is increasing evidence, however, that classic STDs and HIV infection interact in a bidirectional and mutually enhancing manner. Several prospective studies have demonstrated that STDs increase the risk of acquisition or transmission of HIV infectio
The impact of HIV and other STDs on human populations. Are predictions possible? [published erratum appears in Infect Dis Clin North Am 1994 Jun;8(2):xi-xii]: Infect Dis Clin North Am. 1993 Dec;7(4):771-92. Unique Identifier : AIDSLINE MED/94149263; Boily MC; Brunham RC; Department of Medical Microbiology, University of Manitoba,; Winnipeg, Canada.; This article presents an overview of the use of mathematical models to study the demographic impact of STDs. Written for the nonmathematician, the article introduces the basic concepts of mathematical epidemiology for infectious diseases, such as the mass-action principle, the threshold density concept, and the basic
Serologic testing for sexually transmitted diseases.: Infect Dis Clin North Am. 1993 Dec;7(4):793-824. Unique Identifier : AIDSLINE MED/94149264; Thomas DL; Quinn TC; Division of Infectious Diseases, Johns Hopkins University School; of Medicine, Baltimore, Maryland.; This article addresses current issues regarding serologic testing for selected STDs, particularly those for which serologic testing has been useful for diagnosis, monitoring therapy, or seroepidemiology. For each selected pathogen, the authors discuss the strengths and weaknesses of the serologic tests as diagnostic a
Epidemiology of genital herpes infections.: Infect Dis Clin North Am. 1993 Dec;7(4):825-39. Unique Identifier : AIDSLINE MED/94149265; Mertz GJ; Department of Medicine, University of New Mexico, Albuquerque.; Much has been learned in the last decade about the epidemiology of genital herpes infections, including new information about seroprevalence and the risk of transmission of genital herpes to sex partners and at delivery. Unfortunately, the type-specific serologic assays now rout
Prevention of sexually transmitted infections. Physical and chemical barrier methods.: Infect Dis Clin North Am. 1993 Dec;7(4):841-59. Unique Identifier : AIDSLINE MED/94149266; Stratton P; Alexander NJ; National Institute of Child Health and Human Development/Center; for Population Research/Contraceptive Development Branch,; National Institutes of Health, Bethesda, Maryland.; Barrier contraceptives, including mechanical methods, chemical methods, and combinations thereof, have the potential to decrease the spread of STDs, are inexpensive, and do not have any systemic effects. Currently, the concerns that the efficacy of latex condoms is limited because they are not consistently used, they
Defining behavioral methods to prevent sexually transmitted diseases through intervention research.: Infect Dis Clin North Am. 1993 Dec;7(4):861-73. Unique Identifier : AIDSLINE MED/94149267; Aral SO; Peterman TA; Division of STD/HIV Prevention, National Center for Prevention; Services, National Centers for Disease Control and Prevention,; Atlanta, Georgia.; This article focuses on efforts to use behavioral interventions to prevent STDs. Presented is a history of attempts to prevent and control STDs through behavior change and a summary of the main theoretic approaches to human behavior that have provided the scientific base for behavioral public health interventions. The
The relationship between AIDS-related information sources and homophobic attitudes: a comparison of two models.: J Homosex. 1993;25(4):47-68. Unique Identifier : AIDSLINE MED/94149274; Magruder B; Whitbeck LB; Ishii-Kuntz M; Department of Sociology, Iowa State University, Ames 50010.; Using a sample of 914 college students from the Midwest and West Coast, this research compared two possible relationships between information sources about AIDS and homophobic attitudes. The first model examined the effects of various information sources on students accuracy of knowledge regarding AIDS transmission,
The relationship between homophobia and self-esteem in gay males with AIDS.: J Homosex. 1993;25(4):69-76. Unique Identifier : AIDSLINE MED/94149275; Lima G; Lo Presto CT; Sherman MF; Sobelman SA; Department of Psychology, Loyola College in Maryland, Baltimore; 21210.; Fifty-seven participants from various mental health centers and volunteers responding to an ad in a gay newspaper completed questionnaires designed to assess homophobia and self-esteem. Results indicated a significant relationship between homophobia and self-esteem. Moreover, it was found that gay males with AIDS disp
Preexposure prophylaxis with 9-(2-phosphonylmethoxyethyl)adenine against simian immunodeficiency virus infection in macaques.: J Infect Dis. 1994 Feb;169(2):260-6. Unique Identifier : AIDSLINE MED/94149308; Tsai CC; Follis KE; Sabo A; Grant RF; Bartz C; Nolte RE; Benveniste RE; Bischofberger N; Regional Primate Research Center, University of Washington,; Seattle.; A reverse transcriptase inhibitor, 9-(2-phosphonylmethoxyethyl)adenine (PMEA), was evaluated for efficacy against acute simian immunodeficiency virus (SIV) infection in juvenile macaques (Macaca fascicularis). Macaques were pretreated subcutaneously with PMEA for 48 h before SIV inoculation. Drug treatment continued f
Characterization of human immunodeficiency virus type 1 isolates from children in Romania: identification of a new envelope subtype.: J Infect Dis. 1994 Feb;169(2):281-8. Unique Identifier : AIDSLINE MED/94149311; Dumitrescu O; Kalish ML; Kliks SC; Bandea CI; Levy JA; School of Medicine, University of California, San Francisco; 94143-0128.; Human immunodeficiency virus type 1 (HIV-1) isolates recovered from infected children in Romania were characterized for their biologic, serologic, and molecular properties. The isolates were from subjects in different clinical states, and all showed cytopathic properties in periph
Molecular phylogeny of the Mycobacterium avium complex demonstrates clinically meaningful divisions.: J Infect Dis. 1994 Feb;169(2):305-12. Unique Identifier : AIDSLINE GENBANK/L15624; Frothingham R; Wilson KH; Infectious Disease Section, Durham VA Medical Center, NC 27705.; Phylogenetic analysis of nucleotide sequence data is widely used for viral epidemiology. To explore its use in bacterial strain differentiation, the variable 16S-23S rDNA internal transcribed spacer (ITS) in 24 clinical isolates originally identified as Mycobacterium avium complex (MAC) was sequenced. Three isolates h
Primary prophylaxis with pyrimethamine for toxoplasmic encephalitis in patients with advanced human immunodeficiency virus disease: results of a randomized trial. Terry Beirn Community Programs for Clinical Research on AIDS.: J Infect Dis. 1994 Feb;169(2):384-94. Unique Identifier : AIDSLINE MED/94149325; Jacobson MA; Besch CL; Child C; Hafner R; Matts JP; Muth K; Wentworth DN; Neaton JD; Abrams D; Rimland D; et al; Department of Medicine, University of California, San Francisco.; Pyrimethamine, 25 mg thrice weekly, was evaluated as primary prophylaxis for toxoplasmic encephalitis (TE) in a double-blind, randomized clinical trial in patients with human immunodeficiency virus (HIV) disease, absolute CD4 lymphocyte count of
Occupational exposure to human immunodeficiency virus among health care workers in a Danish hospital [letter]: J Infect Dis. 1994 Feb;169(2):478. Unique Identifier : AIDSLINE MED/94149349; Nelsing S; Nielsen TL; Nielsen JO
Sequence variation within the human immunodeficiency virus V3 loop at seroconversion.: J Med Virol. 1993 Dec;41(4):270-4. Unique Identifier : AIDSLINE MED/94149438; Ait-Khaled M; Emery VC; Division of Communicable Diseases, Royal Free Hospital School of; Medicine, London, United Kingdom.; Analysis of the HIV-1 V3 quasispecies present in an individual at the time of seroconversion was carried out. The polymerase chain reaction (PCR) was used to amplify proviral HIV-1 DNA extracted from peripheral blood mononuclear cells from a patient who was viraemic (p24 = 15 pg/ml) and had an equivocal HIV-1 antibody
Inhibition of human immunodeficiency virus reactivation from latency by a tat transdominant negative mutant.: J Med Virol. 1993 Dec;41(4):289-95. Unique Identifier : AIDSLINE MED/94149441; Balboni PG; Bozzini R; Zucchini S; Marconi PC; Grossi MP; Caputo A; Manservigi R; Barbanti-Brodano G; Institute of Microbiology, School of Medicine, University of; Ferrara, Italy.; A BK virus (BKV) expression vector, specific for human cells, was engineered to express antisense human immunodeficiency virus type 1 (HIV-1) tat cDNA (tat-AS) or a tat mutant in cysteine 22 (tat22). Cysteine residues in the cysteine-rich domain of tat are necessary for tat transactivation of the HIV-1 long terminal r
Neutralizing antibody responses to autologous and heterologous isolates of human immunodeficiency virus.: J Acquir Immune Defic Syndr. 1994 Mar;7(3):211-9. Unique Identifier : AIDSLINE MED/94149554; Wrin T; Crawford L; Sawyer L; Weber P; Sheppard HW; Hanson CV; Viral and Rickettsial Disease Laboratory, California Department; of Health Services, Berkeley 94704.; Although laboratory-adapted strains of human immunodeficiency virus (HIV) are generally highly sensitive to neutralization by HIV-positive patient sera, we have found a more complex pattern of cross-neutralization and neutralization resistance among low-passage clinical isolates. These HIV isolates, like many other le
Quantitation by competitive PCR of HIV-1 proviral DNA in epidermal Langerhans cells of HIV-infected patients.: J Acquir Immune Defic Syndr. 1994 Mar;7(3):230-5. Unique Identifier : AIDSLINE MED/94149556; Cimarelli A; Zambruno G; Marconi A; Girolomoni G; Bertazzoni U; Giannetti A; Istituto di Genetica Biochimica ed Evoluzionistica, CNR, Pavia,; Italy.; Langerhans cells (LC) belong to the dendritic cell family and represent the principal antigen presenting cells populating squamous epithelia. We have reported the presence of human immunodeficiency virus Type 1 (HIV-1) proviral DNA and RNA in purified LC from the epidermis of seropositive patients. The aim of this stu
Management of acyclovir-resistant herpes simplex and varicella-zoster virus infections.: J Acquir Immune Defic Syndr. 1994 Mar;7(3):254-60. Unique Identifier : AIDSLINE MED/94149559; Balfour HH Jr; Benson C; Braun J; Cassens B; Erice A; Friedman-Kien A; Klein T; Polsky B; Safrin S; Department of Laboratory Medicine & Pathology, University of; Minnesota Health Sciences Center, Minneapolis.; Persons with AIDS who have CD4+ counts
Central venous catheter infections in AIDS patients receiving treatment for cytomegalovirus disease.: J Acquir Immune Defic Syndr. 1994 Mar;7(3):272-8. Unique Identifier : AIDSLINE MED/94149562; Stanley HD; Charlebois E; Harb G; Jacobson MA; Department of Medicine, University of California, San Francisco.; Central venous catheters (CVC) are commonly used to deliver daily intravenous medications to patients with AIDS, and CVC-associated bacterial infections have been a cause of substantial morbidity in such patients. Although previous studies have reported rates of CVC-associated infections in AIDS patients, none has com
HIV-1 infection incidence among persons with hemophilia in the United States and western Europe, 1978-1990. Multicenter Hemophilia Cohort Study.: J Acquir Immune Defic Syndr. 1994 Mar;7(3):279-86. Unique Identifier : AIDSLINE MED/94149563; Kroner BL; Rosenberg PS; Aledort LM; Alvord WG; Goedert JJ; Research Triangle Institute, Rockville, MD 20852.; We studied human immunodeficiency virus type 1 (HIV-1) infection incidence over time in a 16-center cohort of hemophiliacs in the United States and Europe and estimated the most likely date of seroconversion for all seropositive subjects. Five U.S. centers enrolled subjects independent
Factors influencing survival after AIDS: report from the Multicenter AIDS Cohort Study (MACS).: J Acquir Immune Defic Syndr. 1994 Mar;7(3):287-95. Unique Identifier : AIDSLINE MED/94149564; Saah AJ; Hoover DR; He Y; Kingsley LA; Phair JP; Johns Hopkins School of Hygiene and Public Health, Baltimore, MD; 21205.; The objective of this study was to determine if clinical signs, symptoms, laboratory variables, and use of therapeutic or prophylactic agents have prognostic associations with survival after diagnosis of clinical AIDS. A total of 2,168 homosexual men, seropositive for human immunodeficiency virus type 1 (HIV-1) partic
Risk factors for woman-to-man sexual transmission of the human immunodeficiency virus. Italian Study Group on HIV Heterosexual Transmission.: J Acquir Immune Defic Syndr. 1994 Mar;7(3):296-300. Unique Identifier : AIDSLINE MED/94149565; Nicolosi A; Musicco M; Saracco A; Lazzarin A; Department of Epidemiology and Medical Informatics, University of; Milan, IRCCS Ospedale S. Raffaele, Italy.; A cross-sectional study of stable monogamous couples, recruited from 16 clinical and surveillance centers in Italy between 1987 and 1992, was carried out to investigate the risk factors of woman-to-man sexual transmission of human immunodeficiency virus (HIV). The male partners of a
Risk factors for HIV infection among women in Dar-es-Salaam, Tanzania.: J Acquir Immune Defic Syndr. 1994 Mar;7(3):301-9. Unique Identifier : AIDSLINE MED/94149566; Kapiga SH; Shao JF; Lwihula GK; Hunter DJ; Muhimbili University College of Health Sciences, University of; Dar-es-Salaam, Tanzania.; To identify risk factors for HIV infection among women not known to be members of high-risk groups in Dar-es-Salaam, Tanzania , and assess associations between contraceptive use and HIV infection, we conducted a cross-sectional case-control study at three representative family pla
Rising HIV-1 prevalence among sexually transmitted disease clinic attenders in Jamaica: traumatic sex and genital ulcers as risk factors [see comments]: J Acquir Immune Defic Syndr. 1994 Mar;7(3):310-6. Unique Identifier : AIDSLINE MED/94149567; Figueroa JP; Brathwaite A; Morris J; Ward E; Peruga A; Blattner W; Vermund SH; Hayes R; Ministry of Health, Kingston, Jamaica.; Between November 1990 and January 1991, status of human immunodeficiency virus (HIV) infection was assessed for 522 men and 484 women attending the Comprehensive Health Centre in Kingston, Jamaica , for a new sexually transmitted disease (STD) complaint. Prevalence of HIV type 1 (H
The effect of pregnancy on HIV disease progression [letter; comment]: J Acquir Immune Defic Syndr. 1994 Mar;7(3):317. Unique Identifier : AIDSLINE MED/94149568; Sabin CA; Phillips AN
Choosing facts and caution over fear and convenience.: J Post Anesth Nurs. 1993 Dec;8(6):413-5. Unique Identifier : AIDSLINE MED/94149605; Allen A; It has been said that fear of becoming infected with the human immunodeficiency virus is limiting the quality of care nurses provide. Concern for personal safety has increased with the appearance of acquired immunodeficiency syndrome as well as outbreaks of some other diseases that were thought to be well controlled.
The human immunodeficiency virus type 1 encoded Vpu protein is phosphorylated by casein kinase-2 (CK-2) at positions Ser52 and Ser56 within a predicted alpha-helix-turn-alpha-helix-motif.: J Mol Biol. 1994 Feb 11;236(1):16-25. Unique Identifier : AIDSLINE MED/94149711; Schubert U; Henklein P; Boldyreff B; Wingender E; Strebel K; Porstmann T; Institut fur Medizinische Immunologie, Medizinische Fakultat; (Charite), Humboldt-Universitat zu Berlin, Germany.; The human immunodeficiency virus type 1 (HIV-1) encoded Vpu is a small integral membrane phosphoprotein that functions in the enhancement of viral particle release and has more recently been shown to cause degradation of CD4 at the endoplasmic reticulum. We have demonstrated earlier that Vpu is phosphorylated by the u
The impact of HIV infection in a rural hospital in Haiti.: J Trop Med Hyg. 1994 Feb;97(1):21-5. Unique Identifier : AIDSLINE MED/94149789; Olle-Goig JE; Rodes A; Casabona J; Hopital Albert Schweitzer, Deschapelles, Haiti.; To assess the impact of the human immunodeficiency virus type 1 (HIV) infection on the patients treated at the Medicine Department of the Hopital Albert Schweitzer (HAS) in Haiti and the economic costs to this institution that their medical care caused, a group of HIV infected patie
Alterations of the p53 gene in Epstein-Barr virus-associated immunodeficiency-related lymphomas.: J Virol. 1994 Mar;68(3):1309-15. Unique Identifier : AIDSLINE MED/94149817; Edwards RH; Raab-Traub N; Department of Microbiology and Immunology, University of North; Carolina, Chapel Hill 27599-7295.; Mutations of the p53 tumor suppressor gene are among the most common genetic alterations found in many different human malignancies, including those of the colon, lung, and breast. Alterations in wild-type p53 lead to loss of the suppressor function and thus contribute to tumorigenesis. The potential role of p53 mutat
The presence of tat protein or tumor necrosis factor alpha is critical for herpes simplex virus type 1-induced expression of human immunodeficiency virus type 1.: J Virol. 1994 Mar;68(3):1324-33. Unique Identifier : AIDSLINE MED/94149819; Popik W; Pitha PM; Oncology Center, Johns Hopkins University School of Medicine,; Baltimore, Maryland 21231.; Tat-independent transcription of human immunodeficiency virus type 1 (HIV-1) plays an important role in virus life cycle before biologically significant levels of Tat protein have been accumulated. Using a latently infected T-cell line containing an integrated Tat-defective HIV-1 provirus, we examined whether factors
Neutralization sensitivity of human immunodeficiency virus type 1 is determined in part by the cell in which the virus is propagated.: J Virol. 1994 Mar;68(3):1342-9. Unique Identifier : AIDSLINE MED/94149821; Sawyer LS; Wrin MT; Crawford-Miksza L; Potts B; Wu Y; Weber PA; Alfonso RD; Hanson CV; Viral and Rickettsial Disease Laboratory, California Department; of Health Services, Berkeley 94704.; Neutralizing antibody responses to human immunodeficiency virus type 1 (HIV-1) vary widely and have not been reproducibly associated with prognosis or disease progression. We have found that both low-passage clinical isolates and laboratory-adapted strains of HIV-1 have different sensitivities to neutralization by the
Inhibition of murine AIDS (MAIDS), development by the transplantation of bone marrow cells carrying the Fv-4 resistance gene to MAIDS virus-infected mice.: J Virol. 1994 Mar;68(3):1438-41. Unique Identifier : AIDSLINE MED/94149831; Nakagawa Y; Kakimi K; Ling W; Kubo Y; Higo K; Masuda T; Kuribayashi K; Iwashiro M; Komatz Y; Hirama T; et al; Institute of Virus Research, Kyoto University, Japan.; To examine whether the resistance allele of the Fv-4 gene (the Fv-4r gene) is a dominant inhibitory-product-encoding gene which an be used to prevent the development of murine AIDS (MAIDS), bone marrow cells from BALB/c-Fv-4wr mice were transplanted into BALB/c mice and C57BL/6 mice infected with MAIDS virus. Almost a
Major histocompatibility complex-restricted CD8+ cytotoxic T lymphocytes from horses with equine infectious anemia virus recognize Env and Gag/PR proteins.: J Virol. 1994 Mar;68(3):1459-67. Unique Identifier : AIDSLINE GENBANK/X16988; McGuire TC; Tumas DB; Byrne KM; Hines MT; Leib SR; Brassfield AL; O'Rourke KI; Perryman LE; Department of Veterinary Microbiology and Pathology, Washington; State University, Pullman 99164-7040.; Cytotoxic T lymphocytes (CTL) can control some viral infections and may be important in the control of lentiviruses, including human immunodeficiency virus type 1. Since there is limited evidence for an in vivo role of CTL in control of lentiviruses, dissection of immune mechanisms in animal lentiviral infections may
Activities of the feline immunodeficiency virus integrase protein produced in Escherichia coli.: J Virol. 1994 Mar;68(3):1468-74. Unique Identifier : AIDSLINE MED/94149835; Vink C; van der Linden KH; Plasterk RH; Division of Molecular Biology, The Netherlands Cancer Institute,; Amsterdam.; Retroviral DNA integration requires the activity of at least one viral protein, the integrase (IN) protein. We cloned and expressed the integrase gene of feline immunodeficiency virus (FIV) in Escherichia coli as a fusion to the malE gene and purified the IN fusion protein by affinity chromatography. The protein is ac
Subcellular distribution of human immunodeficiency virus type 1 Rev and colocalization of Rev with RNA splicing factors in a speckled pattern in the nucleoplasm.: J Virol. 1994 Mar;68(3):1475-85. Unique Identifier : AIDSLINE MED/94149836; Kalland KH; Szilvay AM; Langhoff E; Haukenes G; Department of Microbiology and Immunology, Gade Institute,; University of Bergen, Norway.; The human immunodeficiency virus type 1 (HIV-1) Rev (regulator of virion protein expression) protein exemplifies a new type of posttranscriptional regulation. One main function of Rev is to increase the cytoplasmic expression of unspliced and incompletely spliced retroviral mRNAs from which viral structural proteins a
A new subtype of human immunodeficiency virus type 1 (MVP-5180) from Cameroon.: J Virol. 1994 Mar;68(3):1581-5. Unique Identifier : AIDSLINE GENBANK/L20571; Gurtler LG; Hauser PH; Eberle J; von Brunn A; Knapp S; Zekeng L; Tsague JM; Kaptue L; Max von Pettenkofer Institute, University of Munich, Germany.; A new subtype (MVP-5180) of human immunodeficiency virus type 1 (HIV-1) was isolated from a Cameroonian AIDS patient. MVP-5180 was grown in several human T-cell lines and the monocytic U937 line. MVP-5180 DNA could not be amplified by nested primer PCR with conventional env primers and could be only very faintly ampli
Genomic cloning and complete sequence analysis of a highly divergent African human immunodeficiency virus isolate.: J Virol. 1994 Mar;68(3):1586-96. Unique Identifier : AIDSLINE GENBANK/L23119; Vanden Haesevelde M; Decourt JL; De Leys RJ; Vanderborght B; van der Groen G; van Heuverswijn H; Saman E; Innogenetics N.V., Gent, Belgium.; Analysis of the complete sequence of a human immunodeficiency virus (HIV) isolate (Ant70) obtained from a Cameroonian patient indicates that this virus is the most divergent strain within the HIV-1 family hitherto described. Comparison of the Pol protein, usually highly conserved within the HIV-1 family, shows only ab
Mucosal model of genital immunization in male rhesus macaques with a recombinant simian immunodeficiency virus p27 antigen.: J Virol. 1994 Mar;68(3):1624-32. Unique Identifier : AIDSLINE MED/94149853; Lehner T; Tao L; Panagiotidi C; Klavinskis LS; Brookes R; Hussain L; Meyers N; Adams SE; Gearing AJ; Bergmeier LA; Division of Immunology, United Medical School, Guy's Hospital,; London, United Kingdom.; Human immunodeficiency virus (HIV) can be transmitted through infected seminal fluid or vaginal or rectal secretions during heterosexual or homosexual intercourse. To prevent mucosal transmission and spread to the regional lymph nodes, an effective vaccine may need to stimulate immune responses at the genitourinary mu
Genetic analysis of the human immunodeficiency virus type 1 integrase protein.: J Virol. 1994 Mar;68(3):1633-42. Unique Identifier : AIDSLINE MED/94149854; Shin CG; Taddeo B; Haseltine WA; Farnet CM; Division of Human Retrovirology, Dana-Farber Cancer Institute,; Boston, Massachusetts 02115.; Single-amino-acid changes in a highly conserved central region of the human immunodeficiency virus type 1 (HIV-1) integrase protein were analyzed for their effects on viral protein synthesis, virion morphogenesis, and viral replication. Alteration of two amino acids that are invariant among retroviral integrases, D116
Role of the matrix protein in the virion association of the human immunodeficiency virus type 1 envelope glycoprotein.: J Virol. 1994 Mar;68(3):1689-96. Unique Identifier : AIDSLINE MED/94149861; Dorfman T; Mammano F; Haseltine WA; Gottlinger HG; Division of Human Retrovirology, Dana-Farber Cancer Institute,; Boston, Massachusetts 02115.; The matrix (MA) protein of human immunodeficiency virus type 1 (HIV-1) forms an inner coat directly underneath the lipid envelope of the virion. The outer surface of the lipid envelope surrounding the capsid is coated by the viral Env glycoproteins. We report here that the HIV-1 capsid-Env glycoprotein association is
Identification and characterization of a human herpesvirus 6 gene segment capable of transactivating the human immunodeficiency virus type 1 long terminal repeat in an Sp1 binding site-dependent manner [published erratum appears in J Virol 1994 Jun;68(6):4108]: J Virol. 1994 Mar;68(3):1706-13. Unique Identifier : AIDSLINE GENBANK/S57540; Wang J; Jones C; Norcross M; Bohnlein E; Razzaque A; Division of Viral Products, Center for Biologics Evaluation and; Research, Bethesda, Maryland 20892.; The human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR) is transactivated by various extracellular signals and viral cofactors that include human herpesviruses. These transactivators are capable of transactivating the HIV-1 LTR through the transactivation response element, NF-kappa B, or other regul
Cysteine residues in the Vif protein of human immunodeficiency virus type 1 are essential for viral infectivity.: J Virol. 1994 Mar;68(3):1714-20. Unique Identifier : AIDSLINE MED/94149864; Ma XY; Sova P; Chao W; Volsky DJ; Molecular Virology Laboratory, St. Luke's/Roosevelt Hospital; Center, New York, New York 10019.; The infectivity factor of human immunodeficiency virus type 1 (HIV-1), Vif, contains two cysteine residues which are highly conserved among animal lentiviruses. We introduced substitutions of leucine for cysteine residues in the vif gene of a full-length HIV-1 clone to analyze their roles in viral infection. Mutant vi
Viral multiplicity of attachment and its implications for human immunodeficiency virus therapies.: J Virol. 1994 Mar;68(3):1782-9. Unique Identifier : AIDSLINE MED/94149872; Spouge JL; National Center for Biotechnology Information, National Library; of Medicine, Bethesda, Maryland 20894.; The multiplicity of attachment (MOA) of a virion in any particular time interval is the average number of cellular attachment opportunities that must be blocked to keep the virion in suspension. MOA is usually proportional to incubation time and cell concentration. Low MOA (like low multiplicity of infection) is requi
Incomplete protection, but suppression of virus burden, elicited by subunit simian immunodeficiency virus vaccines.: J Virol. 1994 Mar;68(3):1843-53. Unique Identifier : AIDSLINE MED/94149880; Israel ZR; Edmonson PF; Maul DH; O'Neil SP; Mossman SP; Thiriart C; Fabry L; Van Opstal O; Bruck C; Bex F; et al; Department of Pathology, College of Veterinary Medicine and; Biomedical Sciences, Colorado State University, Fort Collins; 80523.; We compared the efficacy of immunization with either simian immunodeficiency virus (SIV) Env glycoprotein (Env), Env plus Gag proteins (Gag-Env), or whole inactivated virus (WIV), with or without recombinant live vaccinia vector (VV) priming, in protecting 23 rhesus macaques (six vaccine and two control groups) from c
Murine AIDS is initiated in the lymph nodes draining the site of inoculation, and the infected B cells influence T cells located at distance, in noninfected organs.: J Virol. 1994 Mar;68(3):1903-12. Unique Identifier : AIDSLINE MED/94149885; Simard C; Huang M; Jolicoeur P; Laboratory of Molecular Biology, Clinical Research Institute of; Montreal, Quebec, Canada.; The infection of cells which belong to the B-cell lineage is thought to be the primary event leading to the phenotypic and functional alterations seen in the murine AIDS (M. Huang, C. Simard, D. Kay, and P. Jolicoeur, J. Virol. 65:6562-6571, 1991). Using in situ hybridization, we studied the time course of the anatomi
Requirement of the Pr55gag precursor for incorporation of the Vpr product into human immunodeficiency virus type 1 viral particles.: J Virol. 1994 Mar;68(3):1926-34. Unique Identifier : AIDSLINE MED/94149887; Lavallee C; Yao XJ; Ladha A; Gottlinger H; Haseltine WA; Cohen EA; Departement de Microbiologie et Immunologie, Faculte de; Medecine, Universite de Montreal, Quebec, Canada.; The human immunodeficiency virus type 1 (HIV-1) particles consists of two molecules of genomic RNA as well as molecules originating from gag, pol, and env products, all synthesized as precursor proteins. The 96-amino-acid Vpr protein, the only virion-associated HIV-1 regulatory protein, is not part of the virus polypr
Enhanced in vitro human immunodeficiency virus type 1 replication in B cells expressing surface antibody to the TM Env protein.: J Virol. 1994 Mar;68(3):1942-50. Unique Identifier : AIDSLINE MED/94149889; Tani Y; Donoghue E; Sharpe S; Boone E; Lane HC; Zolla-Pazner S; Cohen DI; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, Bethesda, Maryland 20892.; The human immunodeficiency virus type 1 (HIV-1) external envelope glycoprotein gp120 tightly binds CD4 as its principal cellular receptor, explaining the tropism of HIV-1 for CD4+ cells. Nevertheless, reports documenting HIV infection or HIV binding in cells lacking CD4 surface expression have raised the possibility t
Photoinactivation and kinetics of membrane fusion mediated by the human immunodeficiency virus type 1 envelope glycoprotein.: J Virol. 1994 Mar;68(3):1956-61. Unique Identifier : AIDSLINE MED/94149891; Dimitrov DS; Blumenthal R; Section on Membrane Structure and Function, National Cancer; Institute, NIH, Bethesda, MD 20892.; The fusion kinetics of cells expressing the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein with CD4 target cells was continuously monitored by image-enhanced Nomarski differential interference contrast optics. The analysis of the videotape recordings showed that (i) cells made contact relatively rap
gp120-independent fusion mediated by the human immunodeficiency virus type 1 gp41 envelope glycoprotein: a reassessment.: J Virol. 1994 Mar;68(3):1977-82. Unique Identifier : AIDSLINE MED/94149895; Marcon L; Sodroski J; Dana-Farber Cancer Institute, Department of Pathology, Harvard; Medical School, Boston, Massachusetts 02115.; In a natural context, membrane fusion mediated by the human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins involves both the exterior envelope glycoprotein (gp120) and the transmembrane glycoprotein (gp41). Perez et al. (J. Virol. 66:4134-4143, 1992) reported that a mutant HIV-1 envelope glycoprotein con
Induction of beta interferon by human immunodeficiency virus type 1 and its gp120 protein in human monocytes-macrophages: role of beta interferon in restriction of virus replication.: J Virol. 1994 Mar;68(3):1983-6. Unique Identifier : AIDSLINE MED/94149896; Gessani S; Puddu P; Varano B; Borghi P; Conti L; Fantuzzi L; Belardelli F; Department of Virology, Istituto Superiore di Sanita, Rome,; Italy.; In vitro cultivated human monocytes show a time-dependent differentiation into macrophages, characterized by an increased expression of macrophage-specific antigens. Monocytes-macrophages were infected with human immunodeficiency virus type 1 strain Ba-L (HIV-1Ba-L) at different stages of differentiation. When 7-day c
Analysis of Tat function in human immunodeficiency virus type 1-infected low-level-expression cell lines U1 and ACH-2.: J Virol. 1994 Mar;68(3):1993-7. Unique Identifier : AIDSLINE MED/94149898; Cannon P; Kim SH; Ulich C; Kim S; Department of Biochemistry, University of Oxford, United Kingdom.; The U1 and ACH-2 cell lines are subclones of human monocytic and T-lymphoid cells, respectively, persistently infected with human immunodeficiency virus type 1. These cell lines harbor the viral genome but produce only very low levels of viral progeny, which can be increased by stimulation with agents such as phorbol
Posttranscriptional effector domains in the Rev proteins of feline immunodeficiency virus and equine infectious anemia virus.: J Virol. 1994 Mar;68(3):1998-2001. Unique Identifier : AIDSLINE MED/94149899; Mancuso VA; Hope TJ; Zhu L; Derse D; Phillips T; Parslow TG; Department of Pathology, University of California, San Francisco; 94143-0506.; By systematically dissecting the Rev proteins of feline immunodeficiency virus (FIV) and equine infectious anemia virus (EIAV), we have identified within each a short peptide that is functionally interchangeable with the effector domains found in Rev-like proteins from other retroviruses. The active sequences from FIV
Characterization of human immunodeficiency virus type 1 variants with increased resistance to a C2-symmetric protease inhibitor.: J Virol. 1994 Mar;68(3):2016-20. Unique Identifier : AIDSLINE MED/94149902; Ho DD; Toyoshima T; Mo H; Kempf DJ; Norbeck D; Chen CM; Wideburg NE; Burt SK; Erickson JW; Singh MK; Aaron Diamond AIDS Research Center, New York University School of; Medicine, New York 10016.; Inhibitors of the human immunodeficiency virus type 1 protease represent a promising class of antiviral drugs for the treatment of AIDS, and several are now in clinical trials. Here, we report the in vitro selection of viral variants with decreased sensitivity to a C2-symmetric protease inhibitor (A-77003). We show th
Reduced nuclear import of human immunodeficiency virus type 1 preintegration complexes in the presence of a prototypic nuclear targeting signal.: J Virol. 1994 Mar;68(3):2021-5. Unique Identifier : AIDSLINE MED/94149903; Gulizia J; Dempsey MP; Sharova N; Bukrinsky MI; Spitz L; Goldfarb D; Stevenson M; Department of Pathology and Microbiology, University of Nebraska; Medical Center, Omaha 68198-5120.; Nuclear import of the retroviral preintegration complex and integration of retroviral with host cell DNA are essential steps for completion of the virus life cycle. The preintegration complex of the lentivirus human immunodeficiency virus type 1 (HIV-1) displays karyophilic properties and, as a consequence, is rapidly
Upstream U3 sequences in simian immunodeficiency virus are selectively deleted in vivo in the absence of an intact nef gene.: J Virol. 1994 Mar;68(3):2031-7. Unique Identifier : AIDSLINE MED/94149905; Kirchhoff F; Kestler HW 3rd; Desrosiers RC; New England Regional Primate Research Center, Harvard Medical; School, Southborough, Massachusetts 01772-9102.; Major transcriptional control elements are located within the U3 region of the long terminal repeats (LTRs) of lentivirus and other retroviral genomes. The nef auxiliary gene of simian immunodeficiency virus (SIV) and human immunodeficiency virus overlaps about 70% of the 450- to 560-bp-long U3 region present in these
[Books recommended by senior nurses and by fresh nurses. A story of an AIDS patient and who supported him]: Kango. 1993 Mar;45(3):75-7. Unique Identifier : AIDSLINE MED/94150057; Katsuta H
Nonrandom chromosomal abnormalities in bovine lymphoma.: Leuk Res. 1994 Feb;18(2):91-9. Unique Identifier : AIDSLINE MED/94150149; Schnurr MW; Carter RF; Dube ID; Valli VE; Jacobs RM; Department of Pathology, University of Guelph, Ontario, Canada.; Despite detailed knowledge of the genetic map of the bovine leukemia virus (BLV), the mechanism whereby BLV infection results in transformation and B-lineage restriction of tumors is poorly understood. The aim of this study was to gain new insight into pathogenetic mechanisms of BLV-induced tumorigenesis by determinin
Reactivation of Chagas' disease successfully treated with benznidazole in a patient with acquired immunodeficiency syndrome.: Mem Inst Oswaldo Cruz. 1993 Jul-Sep;88(3):493-6. Unique Identifier : AIDSLINE MED/94150365; Nishioka S de A; Ferreira MS; Rocha A; Burgarelli MK; Silva AM; Duarte MI; Schmitt FC; Centro de Ciencias Biomedicas, Universidade Federal de; Uberlandia, MG, Brasil.
Australia's first case of AIDS? Pneumocystis carinii pneumonia and HIV in 1981.: Med J Aust. 1994 Mar 7;160(5):247-50. Unique Identifier : AIDSLINE MED/94150378; Gerrard JG; McGahan SL; Milliken JS; Mathys JM; Wills EJ; Royal Prince Alfred Hospital, Camperdown, NSW.; OBJECTIVE: To present the earliest Australian case of the acquired immunodeficiency syndrome (AIDS) reported to date. CLINICAL FEATURES: A 72-year-old man developed a prolonged illness, beginning in February 1981, characterised by anorexia, malaise, weight loss and an episode of herpes zoster. In July he noted the ins
A short history of AIDS.: Med J Aust. 1994 Mar 7;160(5):251-2. Unique Identifier : AIDSLINE MED/94150379; Gold J; Dwyer J; Prince of Wales Hospital, Randwick, NSW.
Pulmonary malakoplakia related to Rhodococcus equi occurring in the acquired immunodeficiency syndrome [letter]: Med J Aust. 1994 Mar 7;160(5):308-9. Unique Identifier : AIDSLINE MED/94150395; Russell GM; Mills AE
What to do when zidovudine fails [editorial; comment]: N Engl J Med. 1994 Mar 10;330(10):706-7. Unique Identifier : AIDSLINE MED/94150524; Saag MS
Racial differences in the use of drug therapy for HIV disease in an urban community [see comments]: N Engl J Med. 1994 Mar 17;330(11):763-8. Unique Identifier : AIDSLINE MED/94150551; Moore RD; Stanton D; Gopalan R; Chaisson RE; Johns Hopkins University School of Medicine, Baltimore, MD 21205.; BACKGROUND. Guidelines for drug therapy in human immunodeficiency virus (HIV) disease are based primarily on the stage of the disease. To determine whether sociodemographic characteristics of patients influence drug therapy in practice, we analyzed the use of antiretroviral therapy and prophylactic therapy for Pneumoc
Declining age at HIV infection in the United States [letter]: N Engl J Med. 1994 Mar 17;330(11):789-90. Unique Identifier : AIDSLINE MED/94150557; Rosenberg PS; Biggar RJ; Goedert JJ
What priority for TB? [editorial]: Nature. 1994 Jan 6;367(6458):2. Unique Identifier : AIDSLINE MED/94150579
US abandons planned AIDS vaccine trial [news]: Nature. 1994 Feb 3;367(6462):399. Unique Identifier : AIDSLINE MED/94150601; Macilwain C
HIV and AIDS [letter]: Nature. 1994 Feb 3;367(6462):405. Unique Identifier : AIDSLINE MED/94150611; Aikman D
UK newspaper goes quiet on challenge to HIV/AIDS link [news]: Nature. 1994 Feb 10;367(6463):500. Unique Identifier : AIDSLINE MED/94150636; Clarke M
AIDS in Africa: is it a myth? [letter]: Nature. 1994 Feb 10;367(6463):504. Unique Identifier : AIDSLINE MED/94150639; Garnett G; Anderson R
When to speak [letter; comment] [see comments]: Nature. 1994 Feb 10;367(6463):504. Unique Identifier : AIDSLINE MED/94150640; Perutz MF
German executives are charged [news]: Nature. 1994 Feb 17;367(6464):584. Unique Identifier : AIDSLINE MED/94150656; Abbott A
Japan faces new questions on HIV in blood ... [news]: Nature. 1994 Feb 17;367(6464):584. Unique Identifier : AIDSLINE MED/94150657; Swinbanks D
Le Monde points a finger at the US [news]: Nature. 1994 Feb 17;367(6464):584. Unique Identifier : AIDSLINE MED/94150658; Butler D
Spectre of AIDS haunts reports of sick cows [news]: Nature. 1994 Feb 17;367(6464):585. Unique Identifier : AIDSLINE MED/94150660; Clayton J
Immunologist takes AIDS hot-seat at NIH [news]: Nature. 1994 Feb 17;367(6464):587. Unique Identifier : AIDSLINE MED/94150662; Macilwain C
Providing culturally sensitive health care to Hispanic clients [see comments]: Nurse Pract. 1993 Dec;18(12):40, 43-6, 50-1. Unique Identifier : AIDSLINE MED/94150900; Caudle P; College of Nursing, University of Arkansas for Medical Sciences,; Little Rock.; By the year 2000, Hispanics will outnumber African Americans and become the majority minority. Statistics reveal that health problems of the three main groups of Hispanics in the United States (Mexican Americans, Puerto Ricans, and Cubans) include diabetes, injuries and violence, subst
Overproduction of NFKB2 (lyt-10) and c-Rel: a mechanism for HTLV-I Tax-mediated trans-activation via the NF-kappa B signalling pathway.: Oncogene. 1994 Mar;9(3):841-52. Unique Identifier : AIDSLINE MED/94151007; Lanoix J; Lacoste J; Pepin N; Rice N; Hiscott J; Terry Fox Molecular Oncology Group, Abe Stern Cancer Research; Laboratory, Lady Davis Institute for Medical Research, Sir; Mortimer B. Davis-Jewish General Hospital, Montreal, Quebec,; Canada.; Molecular, biochemical and epidemiological evidence implicate HTLV-I as an etiologic agent of adult T cell leukemia (ATL). The Tax protein of HTLV-I, a positive transcriptional activator of HTLV-I gene expression, is a viral oncogene that also increases transcription of cellular genes including GM-CSF, IL-2R alpha and
Mechanism of expression and role in transcriptional control of the proto-oncogene NFKB-2/LYT-10.: Oncogene. 1994 Mar;9(3):923-33. Unique Identifier : AIDSLINE MED/94151016; Chang CC; Zhang J; Lombardi L; Neri A; Dalla-Favera R; Department of Pathology, College of Physicians and Surgeons,; Columbia University, New York, New York 10032.; The NFKB-2 gene (previously LYT-10, NF-kappa Bp100 or NF-kappa Bp97) codes for a NF-kappa B/rel related protein which is highly homologous to NFKB-1 (previously NF-kappa Bp105) within its rel, poly-glycine and ankyrin domains. The NFKB-2 gene is a candidate proto-oncogene since it is involved in lymphoma-associated ch
A comparison of immunoglobulin G-containing high-molecular-weight complexes isolated from children with juvenile rheumatoid arthritis and congenital human immunodeficiency virus infection.: Pediatr Res. 1993 Dec;34(6):781-4. Unique Identifier : AIDSLINE MED/94151079; Jarvis JN; Iobidze M; Taylor H; DeJonge J; Chang S; Division of Immunology/Rheumatology, Wayne State University; School of Medicine, Detroit, Michigan 48201.; Circulating immune complexes have been described in both juvenile rheumatoid arthritis and in AIDS. We isolated high-molecular-weight complexes from plasma of children with juvenile rheumatoid arthritis and congenital human immunodeficiency virus infection by sequential gel filtration followed by affinity chromatograp
Penicillium marneffei infection in children infected with human immunodeficiency virus.: Pediatr Infect Dis J. 1993 Dec;12(12):1021-5. Unique Identifier : AIDSLINE MED/94151096; Sirisanthana V; Sirisanthana T; Faculty of Medicine, Chiang Mai University, Thailand.
Zidovudine dosage [letter; comment]: Pediatr Infect Dis J. 1993 Dec;12(12):1037-8. Unique Identifier : AIDSLINE MED/94151104; Stoller J
Human immunodeficiency virus: Munchausen by proxy [letter]: Pediatr Infect Dis J. 1993 Dec;12(12):1038. Unique Identifier : AIDSLINE MED/94151106; Isaacs D; Ziegler J
Bacillus Calmette-Guerin infection after vaccination of human immunodeficiency virus-infected children.: Pediatr Infect Dis J. 1993 Dec;12(12):993-7. Unique Identifier : AIDSLINE MED/94151113; Besnard M; Sauvion S; Offredo C; Gaudelus J; Gaillard JL; Veber F; Blanche S; Departement de Pediatrie, Hopital Necker Enfants, Malades,; Paris, France.; The use of Mycobacterium bovis/Bacillus Calmette-Guerin (BCG) to vaccinate against tuberculosis remains controversial. The development of tuberculosis in human immunodeficiency virus (HIV)-infected children demands specific evaluation of the risk/benefit ratio of BCG vaccination in this situation. In our institution 9
HIV health education failus in rural Uganda [news]: Nurs Times. 1994 Jan 26-Feb 1;90(4):10-1. Unique Identifier : AIDSLINE MED/94151139
Safer sexual practices.: Practitioner. 1993 Dec;237(1533):901-4. Unique Identifier : AIDSLINE MED/94151222; Christie A; Toon P; Employers Advisory Service on HIV/AIDS, Bradford, Yorkshire.
HIV status and confidentiality.: Practitioner. 1994 Jan;238(1534):11-5. Unique Identifier : AIDSLINE MED/94151231; Cohen J; Bury J; Hedge B; University College London Medical School.
Crystal structure of Escherichia coli RNase HI in complex with Mg2+ at 2.8 A resolution: proof for a single Mg(2+)-binding site.: Proteins. 1993 Dec;17(4):337-46. Unique Identifier : AIDSLINE MED/94151286; Katayanagi K; Okumura M; Morikawa K; Protein Engineering Research Institute, Osaka, Japan.; To obtain more precise insight into the Mg(2+)-binding site essential for RNase HI catalytic activity, we have determined the crystal structure of E. coli RNase HI in complex with Mg2+. The analyzed cocrystal, which is not isomorphous with the Mg(2+)-free crystal previously refined at 1.48 A resolution, was grown at a
A small element from the Mason-Pfizer monkey virus genome makes human immunodeficiency virus type 1 expression and replication Rev-independent.: Proc Natl Acad Sci U S A. 1994 Feb 15;91(4):1256-60. Unique Identifier : AIDSLINE MED/94151308; Bray M; Prasad S; Dubay JW; Hunter E; Jeang KT; Rekosh D; Hammarskjold ML; Myles H. Thaler Center for AIDS and Human Retrovirus Research,; University of Virginia, Charlottesville 22908.; Replication of human immunodeficiency virus type 1 (HIV-1) is dependent on the viral Rev protein. This protein acts in concert with the cis-acting rev-responsive element present in intron-containing RNAs to facilitate nuclear export of these RNAs. Here we show that a cis-acting 219-nucleotide sequence from an unrelate
Human immunodeficiency virus type 1 Nef associates with a cellular serine kinase in T lymphocytes.: Proc Natl Acad Sci U S A. 1994 Feb 15;91(4):1539-43. Unique Identifier : AIDSLINE MED/94151365; Sawai ET; Baur A; Struble H; Peterlin BM; Levy JA; Cheng-Mayer C; Department of Medicine, University of California, San Francisco; 94143-0128.; With T-cell lines constitutively expressing Nef from the SF2 strain of human immunodeficiency virus type 1 (HIV-1SF2) in the form of a hybrid CD8-Nef fusion protein or T-cell lines chronically infected with HIV-1SF2, a cellular serine kinase was found that specifically associates with Nef. Proteins of 62 kDa and 72 kD
Cardiac involvement in human immunodeficiency virus infection [editorial]: Q J Med. 1993 Dec;86(12):751-3. Unique Identifier : AIDSLINE MED/94151462; Currie PF; Boon NA
Lymph node pathology in Zimbabwe: a review of 2194 specimens.: Q J Med. 1993 Dec;86(12):811-7. Unique Identifier : AIDSLINE MED/94151469; Sibanda EN; Stanczuk G; Regional Immunology Department, Birmingham Heartlands Hospital,; UK.; When the body s defences are breached by infection, information about such an event is channelled through the lymphatic system to the lymphoid organs in which immune responses occur. The key participants in these responses are lymphocytes, which populate the lymph nodes, spleen, and mucosal lymphoid tissues. Together
[Determinants of the prevalence of hepatitis B viral infection in parenteral drug abusers]: Rev Clin Esp. 1993 Dec;193(9):475-9. Unique Identifier : AIDSLINE MED/94151519; Torrella Ramos A; Hernandez Aguado I; Santos Rubio C; Fernandez Garcia E; Garcia de la Hera M; Avino Rico MJ; Conselleria de Sanitat y Consum, Centros de Informacion y; Prevencion de SIDA (CIPS) de Castellon, Valencia, Alicante.; In order to study the frequency of hepatitis B viral infection and its determinants, we studied 2337 intravenous drug users who visited three AIDS information and prevention centers between 1987 and 1991. The presence of three markers for HBV (AntiHBc, AntiHBs, and AgHBs) and of HIV-1 antibodies was analyzed. A struct
[Focal splenic lesions in an HIV-infected patient]: Rev Clin Esp. 1993 Dec;193(9):491-2. Unique Identifier : AIDSLINE MED/94151524; Fernandez Martinez de Mandojana M; Arrizabalaga J; Iribarren JA; Rodriguez Arrondo F; Garde C; Beguiristain A; Merino Moreno JL; Unidad de Enfermedades Infecciosas, Hospital Nuestra Senora de; Aranzazu, San Sebastian, Guipuzcoa.
[Bacteremia due to Streptococcus pneumoniae (letter; comment)]: Rev Clin Esp. 1993 Dec;193(9):518-9. Unique Identifier : AIDSLINE MED/94151532; Torres-Tortosa M; de Cueto Lopez M; Sanchez-Porto A; Lopez-Prieto D; Canueto Quintero J
[The replication of the educational activities of a course developed by the National Training Program for social health workers for controlling HIV infection]: Recenti Prog Med. 1993 Dec;84(12):843-7. Unique Identifier : AIDSLINE MED/94151539; Gianzi FP; De Santi A; De Mei B; Ceccarelli S; Bertinato L; Greco D; Laboratorio di Epidemiologia e Biostatistica, Istituto Superiore; di Sanita, Roma.; A course for regional trainers was organized by the Working Group for HIV training (PFH) and held in Rome. This course has motivated the participants and has given them the ability to organize similar training activities at local level. The training methodology, the evaluation methods and the objectives used in the co
Experiences of disease and treatment among Chlamydia patients.: Scand J Caring Sci. 1993;7(3):169-73. Unique Identifier : AIDSLINE MED/94151560; Faxelid E; Krantz I; Chlamydia trachomatis infection is a common sexually transmitted disease in Sweden , where counselling and partner notification are tools for prevention. Fifty infected patients (27 women, 23 men) were interviewed at an outpatient department. A majority of the patients felt that the
Care of persons with HIV infection--an ethnonursing approach.: Scand J Caring Sci. 1993;7(3):181-9. Unique Identifier : AIDSLINE MED/94151562; Victor BW; The purpose of the present study is to gain an understanding of the content and the process of care of persons with HIV infection. A qualitative approach comparable to the ethnonursing method was adopted. Data were collected through interviews, participant observations and documentary material from 21 key informan
Theoretical discussion of a model of caring for persons with HIV infection.: Scand J Caring Sci. 1993;7(4):243-50. Unique Identifier : AIDSLINE MED/94151570; Victor BW; A model of caring for persons with HIV infection is presented. The model, which identifies the characteristics of care as a holistic phenomenon, consisting of care actions and caring behaviours, was developed through a qualitative approach comparable to the ethnonursing method. The characteristics of care inherent in
Peripheral T-cell lymphoma in HIV-positive patients.: Rev Paul Med. 1993 May-Jun;111(3):427-9. Unique Identifier : AIDSLINE MED/94151579; Vassallo J; Andrade LA; Pedro RJ; Aranha FJ; Department of Pathology, Faculdade de Medicina, Universidade; Estadual de Campinas (UNICAMP), Sao Paulo, Brasil.; Two cases of peripheral T-cell lymphomas in HIV-positive patients are reported: one case of T-pleomorphic small cell non-Hodgkin lymphoma in a 27 year-old bisexual male, and one case of a T-pleomorphic medium and large cell non-Hodgkin lymphoma in a 27 year-old female, whose husband was drug addicted. Both cases were
AIDS and heterosexuals [letter; comment]: Sci Am. 1994 Feb;270(2):10. Unique Identifier : AIDSLINE MED/94151644; Mills R
AIDS and population control.: Sci Am. 1994 Feb;270(2):124. Unique Identifier : AIDSLINE MED/94151645; Piel G
AIDS and the use of injected drugs.: Sci Am. 1994 Feb;270(2):82-8. Unique Identifier : AIDSLINE MED/94151650; Jarlais DC; Friedman SR; Chemical Dependency Institute, Beth Israel Medical Center.
Theoretical ecology: winning its spurs in the real world [news]: Science. 1994 Feb 25;263(5150):1090-2. Unique Identifier : AIDSLINE MED/94151676; Moffat AS
Requirement for CD8 beta chain in positive selection of CD8-lineage T cells.: Science. 1994 Feb 25;263(5150):1131-3. Unique Identifier : AIDSLINE MED/94151682; Nakayama K; Nakayama K; Negishi I; Kuida K; Louie MC; Kanagawa O; Nakauchi H; Loh DY; Howard Hughes Medical Institute, Washington University School of; Medicine, St. Louis, MO 63110.; CD8 is either an alpha alpha homodimer or an alpha beta heterodimer, although most peripheral CD8-lineage T cells express only the CD8 alpha beta heterodimer. The physiological function of CD8 beta was elucidated with mice that were chimeric for the homozygous disruption of the CD8 beta gene. The CD8 beta-1- T cells d
Relationship between drug use and sexual behaviors and the occurrence of sexually transmitted diseases among high-risk male youth.: Sex Transm Dis. 1993 Nov-Dec;20(6):307-13. Unique Identifier : AIDSLINE MED/94151706; Shafer MA; Hilton JF; Ekstrand M; Keogh J; Gee L; DiGiorgio-Haag L; Shalwitz J; Schachter J; Department of Pediatrics, University of California, San Francisco; 94143.; BACKGROUND AND OBJECTIVES: Sexually active adolescents, especially those in detention, are at high risk for acquisition of sexually transmitted diseases (STDs), including HIV infection. Yet little information is available that describes their risk behaviors associated with STDs. The overall objective was to define the
HIV seroprevalence and reasons for refusing and accepting HIV testing.: Sex Transm Dis. 1993 Nov-Dec;20(6):334-7. Unique Identifier : AIDSLINE MED/94151710; Jones JL; Hutto P; Meyer P; Dowda H; Gamble WB Jr; Gunn RA; South Carolina Department of Health, Columbia.; BACKGROUND AND OBJECTIVES: We sought to evaluate the HIV seropositivity of patients who refused or accepted human immunodeficiency virus (HIV) testing in a South Carolina sexually transmitted diseases (STD) clinic, and the patients reasons for refusing or accepting testing. STUDY DESIGN: A serologic and self-administ
[A case of tuberculous sepsis and cryptosporidiosis in a patient with HIV infection]: Ter Arkh. 1993;65(11):30-1. Unique Identifier : AIDSLINE MED/94151752; Krachenko AV; Iurin OG; Ermak TN; Parkhomenko IuG; Makarova NIu; Gruzdev BM; Nesterov SV; Pokrovskii VV
Kinetics of anti-major histocompatibility complex antibodies after plasma exchange and immunosuppression in a pig model.: Transplant Proc. 1994 Feb;26(1):239-41. Unique Identifier : AIDSLINE MED/94151932; Mousson C; Renard C; Tanter Y; Santona L; Zanetta G; Vaiman M; Rifle G; Laboratory of Nephrology-Hemapheresis-Transplantation, Faculty of; Medicine, Dijon, France.
[Nursing care of patients infected with HIV. Care in home-like surroundings boosts patient's integrity]: Vardfacket. 1993 Jun 3;17(10):II-IV. Unique Identifier : AIDSLINE MED/94152128; Bengtsson L; Holmberg JO; Karlsson A
[HIV/AIDS treatment. Many attenuating drugs but still no remedy]: Vardfacket. 1993 Jun 3;17(10):V-IX. Unique Identifier : AIDSLINE MED/94152129; Sandstrom E
[HIV statistics: number of infected heterosexual persons increases slightly]: Vardfacket. 1993 Jun 3;17(10):X-XI. Unique Identifier : AIDSLINE MED/94152130; Eriksson G; Bottiger M
[Virus diagnosis: ELISA test provides answers on hepatitis and HIV]: Vardfacket. 1993 Jun 3;17(10):XIV-XVI. Unique Identifier : AIDSLINE MED/94152132; Falk B
[Infection protection legislation--compulsory care allowed in a special case]: Vardfacket. 1993 Jun 3;17(10):XVII-XVIII. Unique Identifier : AIDSLINE MED/94152134; Gustavsson O
Establishment of HTLV-I-infected cell lines from French, Guianese and West Indian patients and isolation of a proviral clone producing viral particles.: Virus Res. 1993 Dec;30(3):317-34. Unique Identifier : AIDSLINE MED/94152160; Nicot C; Astier-Gin T; Edouard E; Legrand E; Moynet D; Vital A; Londos-Gagliardi D; Moreau JP; Guillemain B; INSERM, Unite 328, Bordeaux, France.; Human T-cell leukemia virus (HTLV-I) induces adult T cell leukemia/lymphoma (ATL) and a chronic neurological disease named either tropical spastic paraparesis (TSP) or HTLV-I associated myelopathy (HAM). We report here the establishment and characterization of eight HTLV-I-infected lymphoid cell lines derived either f
Ophthalmic disease in patients with unrecognized HIV infection.: Acta Ophthalmol (Copenh). 1993 Oct;71(5):662-5. Unique Identifier : AIDSLINE MED/94152242; Sanders R; Craig EA; France AJ; Urquhart GE; Department of Ophthalmology, Ninewells Hospital and Medical; School, Dundee, Scotland.; HIV disease has a long and relatively asymptomatic incubation period before the onset of AIDS. The ophthalmic manifestations of AIDS are well recognized. Little is known of the incidence or range of ophthalmic disease seen in the latent period of HIV disease. A retrospective analysis of 125 case notes of HIV 1 antibod
Infectious diseases in African children.: Acta Paediatr Jpn. 1993 Dec;35(6):553-8. Unique Identifier : AIDSLINE MED/94152272; Hori H; Watanabe M; Sakurai M; Department of Paediatrics, Mie University School of Medicine,; Japan.; Present status and problems of infectious diseases in African children are detailed. The Department of Paediatrics, Mie University School of Medicine has 10 years experience of international medical cooperation with African countries. At present, the department is participating in two projects in
Stereotactic biopsy in cerebral lesions of AIDS.: Acta Neurochir Suppl (Wien). 1993;58:68-70. Unique Identifier : AIDSLINE MED/94152343; Gildenberg PL; Langford L; Kim JH; Trujillo R; Houston Stereotactic Center, Texas.; The experiences with stereotactic biopsies in 121 patients with AIDS compared to 142 non-AIDS patients are presented. In the AIDS group most of the tumors (38) were lymphomas (34). Other frequent diagnoses have been progressive multifocal leukoencephalopathy (20) and toxoplasmosis (16)--although most AIDS patients alr
Diagnosis of thoracic complications in AIDS: accuracy of CT.: AJR Am J Roentgenol. 1994 Mar;162(3):547-53. Unique Identifier : AIDSLINE MED/94152559; Hartman TE; Primack SL; Muller NL; Staples CA; Department of Radiology, University of British Columbia,; Vancouver, Canada.; OBJECTIVE. The purpose of this study was to assess the accuracy of CT interpretation in the diagnosis of thoracic complications of AIDS. If CT is accurate, more invasive diagnostic procedures can be avoided. MATERIALS AND METHODS. We reviewed the CT scans of 102 patients who had AIDS with proved thoracic complications
Trends in survival among persons with acquired immunodeficiency syndrome in New York City. The experience of the first decade of the epidemic.: Am J Epidemiol. 1994 Feb 15;139(4):351-61. Unique Identifier : AIDSLINE MED/94152638; Blum S; Singh TP; Gibbons J; Fordyce EJ; Lessner L; Chiasson MA; Weisfuse IB; Thomas PA; New York City Department of Health, New York.; This study examined survival trends among the 23,324 cases of acquired immunodeficiency syndrome (AIDS) meeting the Centers for Disease Control (CDC) definition that were diagnosed and reported to the New York City Department of Health from the beginning of the epidemic in 1980 through June 1989. The survival patterns
Risk of other cancers following Kaposi's sarcoma: relation to acquired immunodeficiency syndrome.: Am J Epidemiol. 1994 Feb 15;139(4):362-8. Unique Identifier : AIDSLINE MED/94152639; Biggar RJ; Curtis RE; Cote TR; Rabkin CS; Melbye M; Epidemiology and Biostatistics Program, National Cancer; Institute, Bethesda, MD.; To evaluate the risk of another cancer among persons who initially developed Kaposi s sarcoma, the authors used data from the Surveillance, Epidemiology, and End Results (SEER) program of the National Cancer Institute for the years 1973-1990. In persons under 70 years of age, 4,946 cases of Kaposi s sarcoma were obser
Management of chronic hepatitis in special populations.: Am J Med. 1994 Jan 17;96(1A):57S-60S. Unique Identifier : AIDSLINE MED/94152661; Lindsay KL; Department of Medicine, University of Southern California, Los; Angeles 90033.; Over the last several years, much progress has been made in the treatment of adult patients with chronic viral hepatitis and compensated liver disease in the absence of significant other illnesses. However, the treatment of chronic viral hepatitis in other patient populations is still experimental. These groups includ
Undetected HIV infection among patients admitted to an alcohol rehabilitation unit.: Am J Psychiatry. 1994 Mar;151(3):439-40. Unique Identifier : AIDSLINE MED/94152735; Mahler J; Yi D; Sacks M; Dermatis H; Stebinger A; Card C; Perry S; Department of Psychiatry, Cornell University Medical College, New; York.; Of 300 patients admitted to an alcohol rehabilitation unit, serological testing of discarded admission blood samples revealed that 31 (10.3%) had HIV infection. Chart records indicated that four patients were known to be HIV infected on admission, and HIV infection was detected in another three patients during hospita
Trial of immunosuppression in amyotrophic lateral sclerosis using total lymphoid irradiation [see comments]: Ann Neurol. 1994 Feb;35(2):142-50. Unique Identifier : AIDSLINE MED/94152998; Drachman DB; Chaudhry V; Cornblath D; Kuncl RW; Pestronk A; Clawson L; Mellits ED; Quaskey S; Quinn T; Calkins A; et al; Johns Hopkins University, School of Medicine, Baltimore, MD; 21287-7519.; Although the cause of amyotrophic lateral sclerosis (ALS) remains unknown, recent studies have suggested an autoimmune mechanism of pathogenesis. Previous trials of immunosuppressive treatment have yielded inconclusive results. Our study was designed to determine whether more powerful and prolonged immunosuppression,
Zidovudine therapy and myopathies associated with human immunodeficiency virus infection [letter; comment]: Ann Neurol. 1994 Feb;35(2):247-8. Unique Identifier : AIDSLINE MED/94153017; Chariot P; Ruet E; Gherardi R
In vitro anti-human immunodeficiency virus (HIV) activity of XM323, a novel HIV protease inhibitor.: Antimicrob Agents Chemother. 1993 Dec;37(12):2606-11. Unique Identifier : AIDSLINE MED/94153034; Otto MJ; Reid CD; Garber S; Lam PY; Scarnati H; Bacheler LT; Rayner MM; Winslow DL; Du Pont Merck Pharmaceutical Company, Glenolden, Pennsylvania; 19036.; XM323 represents a novel class of potent inhibitors of human immunodeficiency virus (HIV) protease. In vitro studies have shown that inhibition of this enzyme translates into potent inhibition of replication of HIV type 1 (HIV-1) and HIV-2. The inhibition of virus replication was assessed with three assays designed to
Risk perception, universal precautions compliance. A descriptive study of nurses who circulate.: AORN J. 1994 Jan;59(1):253-66. Unique Identifier : AIDSLINE MED/94153068; Ronk LL; Girard NJ; Wilford Hall Medical Center, Lackland AFB, Tex.
Total body protein status of males infected with the human immunodeficiency virus.: Basic Life Sci. 1993;60:197-200. Unique Identifier : AIDSLINE MED/94153241; Oliver CJ; Rose A; Blagojevic N; Dwyer R; Gold J; Allen BJ; Albion Street Centre, Surry Hills NSW, Australia.
Prevalence and transmission of HTLV-I infection in Natal/KwaZulu [published erratum appears in S Afr Med J 1993 Dec;83(12):924]: S Afr Med J. 1993 Sep;83(9):665-7. Unique Identifier : AIDSLINE MED/94143811; Bhigjee AI; Vinsen C; Windsor IM; Gouws E; Bill PL; Tait D; Department of Neurology, University of Natal, Durban.; A community-based seroprevalence survey for human T-cell lymphotropic virus type I (HTLV-I) was undertaken in the Ngwelezane district of Natal/KwaZulu. A total of 1,018 individuals was interviewed for risk factors and had blood drawn for serological examination. To exclude antibody cross-reactivity between anti-HTLV-I
National strategy for serological diagnosis of HIV infection. Subcommittee of the AIDS Advisory Group on Strategies for HIV Testing [published erratum appears in S Afr Med J 1993 Dec;83(12):924]: S Afr Med J. 1993 Sep;83(9):685-7. Unique Identifier : AIDSLINE MED/94143815; Fleming AF; Martin DJ; School of Pathology, South African Institute for Medical; Research, Baragwanath Hospital, Johannesburg.
Simultaneous lung infections in patients with acquired immunodeficiency syndrome [letter; comment]: Arch Intern Med. 1994 Feb 14;154(3):342. Unique Identifier : AIDSLINE MED/94127917; Pierce JR Jr
Multiple system atrophy with autonomic failure and human T-lymphotrophic virus type I infection [letter; comment]: Ann Neurol. 1994 Feb;35(2):244. Unique Identifier : AIDSLINE MED/94153013; Yokota T; Miura Y; Yamada M; Kaneko K; Miyatake T
Destroying the distance [see comments]: Am J Nurs. 1993 Dec;93(12):20. Unique Identifier : AIDSLINE MED/94136522; Carr P; Florida Home Health Services, Sarasota, Inc.
Consent for HIV testing [letter] [see comments]: S Afr Med J. 1993 Sep;83(9):690. Unique Identifier : AIDSLINE MED/94143819; Fennell WM
Cost concerns blamed for AIDS test hold-ups [news] [see comments]: Nature. 1994 Feb 24;367(6465):673. Unique Identifier : AIDSLINE MED/94150689; Butler D
Fournier's gangrene and HIV: wider issues [letter]: Genitourin Med. 1994 Feb;70(1):73. Unique Identifier : AIDSLINE MED/94131466; Luzzi GA
Treatment of bacterial sexually transmitted diseases [published erratum appears in Semin Dermatol 1994 Jun;13(2):151]: Semin Dermatol. 1993 Dec;12(4):342-51. Unique Identifier : AIDSLINE MED/94145868; Elsner P; Department of Dermatology, University of Zurich, Switzerland.; Sexually transmitted diseases (STD) cause significant morbidity in the industrialized nations and, even more so in third world countries. Genital ulcerative STD such as herpes genitalis, syphilis, and chancroid have been identified as important risk factors for the spread of human immunodeficiency virus infection. Eff
Selective anergy of V beta 8+ T cells in human immunodeficiency virus-infected individuals.: J Exp Med. 1994 Feb 1;179(2):413-24. Unique Identifier : AIDSLINE MED/94125022; Dadaglio G; Garcia S; Montagnier L; Gougeon ML; Departement SIDA et Retrovirus, Institut Pasteur, Paris,; France.; We have analyzed the V beta usage by CD4+ and CD8+ T cells from human immunodeficiency virus (HIV)-infected individuals in response to an in vitro stimulation with the superantigenic erythrogenic toxin A (ETA) of Streptococcus pyogenes. ETA amplifies specifically CD4+ and CD8+ T cells from control donors expressing th
Care of pregnant women infected with HIV [letter; comment]: JAMA. 1994 Jan 26;271(4):271-2. Unique Identifier : AIDSLINE MED/94125495; Wortley P; Chu SY; Blostein J; Farley T; Morrison L; Kovacs A; Thompson S 3rd
Medically acquired HIV [news]: Lancet. 1994 Jan 1;343(8888):47. Unique Identifier : AIDSLINE MED/94125696; Ragg M
Fiery entrance for the HIV co-receptor [news]: Lancet. 1994 Jan 1;343(8888):49. Unique Identifier : AIDSLINE MED/94125697; Thompson C
Vaccine-associated paralytic poliomyelitis and HIV infection [letter]: Lancet. 1994 Jan 1;343(8888):51-2. Unique Identifier : AIDSLINE MED/94125700; Ion-Nedelcu N; Dobrescu A; Strebel PM; Sutter RW
HIV contamination of poliovaccines [letter; comment] [see comments]: Lancet. 1994 Jan 1;343(8888):52-3. Unique Identifier : AIDSLINE MED/94125701; Stricker RB; Elswood BF
HIV contamination of poliovaccines [letter; comment]: Lancet. 1994 Jan 1;343(8888):53. Unique Identifier : AIDSLINE MED/94125703; Arya SC
Co-infection and synergy of human immunodeficiency virus-1 and herpes simplex virus-1.: Lancet. 1994 Jan 29;343(8892):255-8. Unique Identifier : AIDSLINE MED/94125736; Heng MC; Heng SY; Allen SG; Department of Medicine, UCLA San Fernando Valley Internal; Medicine Program, Veterans Affairs Medical Center, Sepulveda; 91343.; The human immunodeficiency virus (HIV-1) uses the CD4 molecule, expressed by T helper cells and activated macrophages, as a receptor for entry into host cells. In tissues co-infected with herpes simplex type 1 (HSV-1), HIV-1 virions were observed to infect keratinocytes, which, because they lack the CD4 molecule, are
Cytomegalovirus reactivation and tumour necrosis factor.: Lancet. 1994 Jan 29;343(8892):268-9. Unique Identifier : AIDSLINE MED/94125742; Docke WD; Prosch S; Fietze E; Kimel V; Zuckermann H; Klug C; Syrbe U; Kruger DH; von Baehr R; Volk HD; Institute of Medical Immunology, Medical School-Charite,; Humboldt University, Berlin, Germany.; Tumour necrosis factor-alpha (TNF) stimulates cytomegalovirus ( CMV ) activity in a transfected human monocytic cell line. We assessed whether this finding is relevant in vivo by evaluating the frequency of active CMV infection
Oral ganciclovir [news]: Lancet. 1994 Feb 5;343(8893):349. Unique Identifier : AIDSLINE MED/94125798; Nau JY
Free AIDS database [news]: Lancet. 1994 Feb 5;343(8893):351. Unique Identifier : AIDSLINE MED/94125799
New UN programme on AIDS [news]: Lancet. 1994 Feb 5;343(8893):351. Unique Identifier : AIDSLINE MED/94125800
UK AIDS campaign halted [news]: Lancet. 1994 Feb 5;343(8893):351. Unique Identifier : AIDSLINE MED/94125801; Ramsay S
Breastfeeding and HIV in African countries [letter; comment]: Lancet. 1994 Feb 5;343(8893):362. Unique Identifier : AIDSLINE MED/94125821; Cutting WA
Breastfeeding and HIV in African countries [letter; comment]: Lancet. 1994 Feb 5;343(8893):362. Unique Identifier : AIDSLINE MED/94125822; De Clercq A
Vaginal microbicides and prevention of HIV infection [letter]: Lancet. 1994 Feb 5;343(8893):362-3. Unique Identifier : AIDSLINE MED/94125823; Stein ZA
[Pneumocystis carinii pneumonia during therapy with 2-chlorodeoxyadenosine (2-CDA)]: Schweiz Med Wochenschr. 1994 Jan 11;124(1-2):73-8. Unique Identifier : AIDSLINE MED/94126703; Haberthur C; Pless M; Tichelli A; Gratwohl A; Speck B; Betticher DC; Departement Innere Medizin, Kantonsspital Basel.; We report the case of a 70-year-old patient with B-cell chronic lymphocytic leukemia. During therapy with the new purine analog 2-chloro-deoxyadenosine (2-CDA) the patient developed Pneumocystis carinii pneumonia (PCP). Although the mechanism of action of 2-CDA suggests the incidence of opportunistic infections and th
[Survival of patients with zidovudine resistant HIV]: Ugeskr Laeger. 1994 Jan 10;156(2):185-6. Unique Identifier : AIDSLINE MED/94126958; Gotzsche PC; Nielsen C; Gerstoft J; Nielsen CM; Vestergaard BF; Epidemiafdeling M, Rigshospitalet, Kobenhavn.; The survival of 35 patients with AIDS or advanced HIV infection on zidovudine treatment was related to the viral sensitivity to the drug and to the CD4+ cell count. Fourteen patients died, the survivors were followed up for an average of 804 days. In a univariate Cox model, survival was strongly related to log IC90 (p
Inhibitory effect of coumarins on HIV-1 replication and cell-mediated or cell-free viral transmission.: Acta Virol. 1993 Aug;37(4):241-50. Unique Identifier : AIDSLINE MED/94127346; Bourinbaiar AS; Tan X; Nagorny R; Department of Pediatrics, NYU Medical Center, NY 10016.; A single dose of coumarin derivatives, warfarin, 4-hydroxycoumarin and umbelliferone, added at the time of inoculation either by free virus or by contact with U1 monocytes exhibited a dose-dependent inhibitory effect on viral replication in target MOLT-4 lymphocytes observable even at 5 days post infection. In additio
Factors associated with survival in human immunodeficiency virus-infected patients with very low CD4 counts [see comments]: Am J Epidemiol. 1994 Jan 15;139(2):206-18. Unique Identifier : AIDSLINE MED/94127459; Colford JM Jr; Ngo L; Tager I; Center for AIDS Prevention Studies, University of California, San; Francisco.; The authors examined the survival experience of 289 human immunodeficiency virus (HIV)-infected men to identify factors independently associated with survival in patients with very low CD4 counts (
Distribution of immunocompetent cells in oral Kaposi's sarcoma (AIDS).: Eur J Cancer B Oral Oncol. 1993 Jul;29B(3):209-13. Unique Identifier : AIDSLINE MED/94129345; Tabata M; Langford A; Becker J; Reichart PA; Department of Oral and Maxillofacial Surgery, Kagoshima; University Dental School, Japan.; Fifteen biopsy specimens of oral AIDS-associated Kaposi s sarcoma (KS), 19 biopsy specimens of uninvolved oral mucosa of HIV-seropositive patients (HIV+) and 22 biopsy specimens of oral mucosa of HIV-seronegative persons (HIV-) were analysed for the distribution of CD4+ and CD8+ lymphocytes and HLA-DR+ cells. The resu
Immune reconstitution following peripheral blood stem cell transplantation, autologous bone marrow transplantation and allogeneic bone marrow transplantation.: Bone Marrow Transplant. 1993 Nov;12(5):469-75. Unique Identifier : AIDSLINE MED/94129521; Roberts MM; To LB; Gillis D; Mundy J; Rawling C; Ng K; Juttner CA; Haematology Department, Institute of Medical and Veterinary; Science, Adelaide, Australia.; The rate and pattern of recovery of total lymphocytes, T cell subsets, B cells and NK cells were compared for 12 months following recovery phase peripheral blood stem cell (PBSC) autotransplantation (n = 49), autologous (n = 7) and allogeneic BMT (n = 11). The PBSC group had a significantly faster recovery of total ly
Lymphocyte subsets, sIL2-R and sICAM-1 in blood during allergen challenge tests in asthmatic children.: Pediatr Allergy Immunol. 1993 Nov;4(4):208-13. Unique Identifier : AIDSLINE MED/94129696; Schmitt M; Niggemann B; Kleinau I; Nasert S; Kapp A; Wahn U; University Childrens Hospital (KAVH), Berlin, Germany.; In order to study cell activation in peripheral blood on bronchial allergen provocation up to 24 h, we investigated 32 asthmatic children, sensitive to house-dust mites. Six healthy young adult volunteers served as controls. Lymphocyte subsets (CD3, CD19, CD4, CD8) and activation markers (CD25-T, HLADR-T, CD23) in per
Age-related changes in human blood lymphocyte subpopulations. II. Varying kinetics of percentage and absolute count measurements.: Clin Immunol Immunopathol. 1994 Feb;70(2):152-8. Unique Identifier : AIDSLINE MED/94130399; Hulstaert F; Hannet I; Deneys V; Munhyeshuli V; Reichert T; De Bruyere M; Strauss K; Becton Dickinson Immunocytometry Systems, Erembodegem-Aalst,; Belgium.; A reference range for lymphocyte populations, with particular emphasis on T lymphocyte subsets, was obtained for normal individuals covering age cohorts from birth through adulthood. This report confirms and extends findings from a developmental reference range published earlier (1). Absolute numbers of WBC, lymphocyt
V beta gene repertoires in T cells expanded in local self-healing and lethal systemic murine cutaneous leishmaniasis.: Eur J Immunol. 1994 Feb;24(2):492-5. Unique Identifier : AIDSLINE MED/94130974; Lohoff M; Steinert M; Weiss A; Rollinghoff M; Balderas RS; Theofilopoulos AN; Institut fur klinische Mikrobiologie, Erlangen, FRG.; Inbred mice infected with Leishmania major promastigotes display two different courses of leishmaniasis: resistant strains develop self-healing local sores, while susceptible strains show progressive systemic disease with lethal outcome. Resistance predominantly correlates with the production of T helper type 1 (TH1)
In vitro maturation of human neonatal CD4 T lymphocytes. I. Induction of IL-4-producing cells after long-term culture in the presence of IL-4 plus either IL-2 or IL-12.: J Immunol. 1994 Feb 1;152(3):1141-53. Unique Identifier : AIDSLINE MED/94132609; Wu CY; Demeure CE; Gately M; Podlaski F; Yssel H; Kiniwa M; Delespesse G; University of Montreal, Notre-Dame Hospital Research Center,; Canada.; Recent studies in the mouse have established that IL-4 and IL-12 direct the development of Ag-stimulated naive CD4 T cells into, respectively, type 2 and type 1 Th cells. We report that prolonged exposure of immunologically naive and unstimulated human neonatal CD4 T cells to IL-4 or to IL-4 plus either
Effects of CD45 on NF-kappa B. Implications for replication of HIV-1.: J Immunol. 1994 Feb 1;152(3):976-83. Unique Identifier : AIDSLINE MED/94132650; Baur A; Garber S; Peterlin BM; Howard Hughes Medical Institute, University of California at San; Francisco 94143-0724.; Increased levels of replication of the HIV type 1 are observed after the activation of infected T cells through the TCR. However, anti-CD45 antibodies inhibit these effects in cells from infected individuals. In this study, we examined interrelationships between CD45 and HIV-1 further. We measured effects on the HIV-1
Proliferative response of CD4+ and CD8+ T cell subsets from Hispanics with HIV+ and AIDS: the superantigen hypothesis.: J Acquir Immune Defic Syndr. 1994 Feb;7(2):124-8. Unique Identifier : AIDSLINE MED/94133080; Eylar EH; Rivera-Quinones C; Laroche HI; Yamamura Y; Ponce School of Medicine, Department of Biochemistry, Puerto; Rico.; It has been hypothesized that the progressive deletion of CD4+ T cells in the course of infection due to human immunodeficiency virus (HIV) may be mediated in part by interaction with a superantigen inherent in an HIV protein. Consequently, selective loss of CD4+ cells with a T cell receptor V beta-chain capable of in
Resistance to AZT and ddC during long-term combination therapy in patients with advanced infection with human immunodeficiency virus.: J Acquir Immune Defic Syndr. 1994 Feb;7(2):135-8. Unique Identifier : AIDSLINE MED/94133082; Richman DD; Meng TC; Spector SA; Fischl MA; Resnick L; Lai S; Department of Pathology, University of California, San Diego, La; Jolla 92093-0679.; To ascertain whether combination therapy with zidovudine ( AZT ) and zalcitabine ( ddC ) delayed the emergence of AZT resistance, isolate
The safety and efficacy of combination N-butyl-deoxynojirimycin (SC-48334) and zidovudine in patients with HIV-1 infection and 200-500 CD4 cells/mm3.: J Acquir Immune Defic Syndr. 1994 Feb;7(2):139-47. Unique Identifier : AIDSLINE MED/94133083; Fischl MA; Resnick L; Coombs R; Kremer AB; Pottage JC Jr; Fass RJ; Fife KH; Powderly WG; Collier AC; Aspinall RL; et al; University of Miami School of Medicine, Florida.; We conducted a double-blind, randomized phase II study to evaluate the safety and activity of combination therapy with N-butyl-deoxynojirimycin (SC-48334) (an alpha-glucosidase I inhibitor) and zidovudine versus zidovudine alone. Patients with 200 to 500 CD4 cells/mm3
Severity and outcome of Pneumocystis carinii pneumonia (PCP) in patients of known and unknown HIV status.: J Acquir Immune Defic Syndr. 1994 Feb;7(2):148-53. Unique Identifier : AIDSLINE MED/94133084; Mallal SA; Martinez OP; French MA; James IR; Dawkins RL; Department of Clinical Immunology, Royal Perth Hospital, Western; Australia.; Of 170 Western Australian patients who had their first AIDS-defining illness between 1 January 1983 and 31 December 1991, 61 (36%) were of unknown HIV antibody status (AIDS presenters), while 109 (64%) were of known HIV antibody status (HIV presenters). Pneumocystis carinii pneumonia (PCP) was less common as the AIDS-
Predicting CD4 counts in HIV-infected Brazilian individuals: a model based on the World Health Organization staging system.: J Acquir Immune Defic Syndr. 1994 Feb;7(2):163-8. Unique Identifier : AIDSLINE MED/94133087; Schechter M; Zajdenverg R; Machado LL; Pinto ME; Lima LA; Perez MA; AIDS Program, Hospital Universitario Clementino Fraga Filho,; Federal University of Rio de Janeiro, Brazil.; CD4 cell counts are one of the best available surrogate markers for disease progression; they are widely used laboratory parameters in clinical trials and commonly used indicators for the introduction of primary prophylaxis and antiretroviral therapy. However, measurement is too expensive to be done in most developing
Circadian variation of the CD4 count among drug users [letter]: J Acquir Immune Defic Syndr. 1994 Feb;7(2):205-6. Unique Identifier : AIDSLINE MED/94133096; Mientjes GH; van Ameijden EJ; van den Hoek JA; Roos MT; Coutinho RA
Redistribution of HIV outside the lymphoid system with onset of AIDS.: Lancet. 1994 Feb 12;343(8894):383-5. Unique Identifier : AIDSLINE MED/94133798; Donaldson YK; Bell JE; Ironside JW; Brettle RP; Robertson JR; Busuttil A; Simmonds P; Department of Medical Microbiology, University of Edinburgh, UK.; The basis for many of the symptoms and pathological changes found in patients with the acquired immunodeficiency syndrome (AIDS) remains poorly understood. We have used a quantitative polymerase chain reaction technique to investigate the extent to which direct infection with human immunodeficiency virus (HIV) produce
Maternal IgG1 and IgA antibody to V3 loop consensus sequence and maternal-infant HIV-1 transmission [see comments]: Lancet. 1994 Feb 12;343(8894):390-1. Unique Identifier : AIDSLINE MED/94133801; Markham RB; Coberly J; Ruff AJ; Hoover D; Gomez J; Holt E; Desormeaux J; Boulos R; Quinn TC; Halsey NA; Department of Immunology and Infectious Diseases, Johns Hopkins; University School of Hygiene and Public Health, Baltimore, MD; 21205.; Maternal-infant transmission of HIV-1 occurs in 13-40% of pregnancies. Studies on transmission of maternal immunity to HIV antigens have used antigens from viruses not representative of clinical isolates and have been conflicting. Using a consensus peptide sequence based on HIV isolates found in
HIV infection in Vietnam [news]: Lancet. 1994 Feb 12;343(8894):410. Unique Identifier : AIDSLINE MED/94133807; Nguyen TH; Wolffers I
Patient-to-patient transmission of HIV [letter; comment]: Lancet. 1994 Feb 12;343(8894):415; discussion 415-6. Unique Identifier : AIDSLINE MED/94133811; Collignon P
Patient-to-patient transmission of HIV [letter; comment]: Lancet. 1994 Feb 12;343(8894):415; discussion 415-6. Unique Identifier : AIDSLINE MED/94133812; Shields JW
Patient-to-patient transmission of HIV [letter; comment]: Lancet. 1994 Feb 12;343(8894):416. Unique Identifier : AIDSLINE MED/94133813; Berry G; Fung SC
Patient-to-patient transmission of HIV [letter; comment]: Lancet. 1994 Feb 12;343(8894):416. Unique Identifier : AIDSLINE MED/94133814; Mortimer P; Heptonstall J
Tuberculosis and HIV infection [letter; comment] [see comments]: Lancet. 1994 Feb 12;343(8894):416-7. Unique Identifier : AIDSLINE MED/94133815; Reeve P
Diarrhoea associated with Clostridium difficile in AIDS patients receiving rifabutin [letter]: Lancet. 1994 Feb 12;343(8894):417. Unique Identifier : AIDSLINE MED/94133816; McBride MO; Coker RJ; Horner PJ; Weston R; Weber JN
Co-expression of CD45RA (naive) and CD45R0 (memory) T-cell markers [letter; comment]: Lancet. 1994 Feb 12;343(8894):424. Unique Identifier : AIDSLINE MED/94133831; Peakman M; Mahalingam M; Leslie RD; Vergani D
Human immunodeficiency virus type 1 mRNA expression in peripheral blood cells predicts disease progression independently of the numbers of CD4+ lymphocytes.: Proc Natl Acad Sci U S A. 1994 Feb 1;91(3):1104-8. Unique Identifier : AIDSLINE MED/94134706; Saksela K; Stevens C; Rubinstein P; Baltimore D; Rockefeller University, New York, NY 10021.; To address the significance of human immunodeficiency virus (HIV) replication in peripheral blood mononuclear cells (PBMCs), we have used reverse transcriptase-initiated PCR to measure HIV-1 mRNA expression in PBMC specimens collected from a cohort of HIV-infected individuals during a long-term prospective study. We f
MHC-I non-restricted cytotoxic activity in Macaca sylvana experimentally inoculated with HIV2 and SIV/mac.: Thymus. 1993 Aug;22(1):1-12. Unique Identifier : AIDSLINE MED/94135814; Charaf B; Sanhadji K; Sekkat S; Farouqui B; Touraine JL; Benslimane A; Laboratoire d'Immunovirologie, Institut Pasteur du Maroc,; Casablanca.; The anti-retrovirus cell-mediated immunity was repeatedly investigated in seven monkeys (Macaca sylvana). Four of these animals were injected with cell-free supernatants containing human immunodeficiency viruses: two monkeys received HIV1 Bru (2.5 x 10(6) cpm), two received HIV2 Rod (1.5 x 10(6) cpm). Two additional a
[A new variant of the simian T-lymphotropic retrovirus type I (STLV-IF) in the Sukhumi colony of hamadryas baboons]: Vopr Virusol. 1993 Nov-Dec;38(6):249-53. Unique Identifier : AIDSLINE MED/94135953; Chikobaeva MG; Schatzl H; Rose D; Bush U; Iakovleva LA; Deinhardt F; Helm K; Lapin BA; Polymerase chain reaction (PCR) was developed for the detection of simian T-lymphotropic virus type 1 (STLV-1) infection of P. hamadryas and direct sequencing using oligo-nucleotide primer pairs specific for the tax and env regions of the related human T-lymphotropic virus type 1 (HTLV-1). Excellent specificity was sh
Didanosine compared with continuation of zidovudine in HIV-infected patients with signs of clinical deterioration while receiving zidovudine. A randomized, double-blind clinical trial. The Bristol-Myers Squibb AI454-010 Study Group [see comments]: Ann Intern Med. 1994 Mar 1;120(5):360-8. Unique Identifier : AIDSLINE MED/94136841; Spruance SL; Pavia AT; Peterson D; Berry A; Pollard R; Patterson TF; Frank I; Remick SC; Thompson M; MacArthur RD; et al; Holy Cross Hospital, Salt Lake City, Utah.; OBJECTIVE: To determine the benefits of switching to didanosine compared with continuing zidovudine among patients infected with human immunodeficiency virus (HIV) who have previously used zidovudine and have signs of clinical deterioration. DESIGN: Randomized, double-blind, two-armed, parallel, comparative clinical t
IUCH Working Group on HIV, AIDS & STD.: Arctic Med Res. 1993 Oct;52(4):183-4. Unique Identifier : AIDSLINE MED/94137306
Destructive networks in AIDS [letter]: Immunol Today. 1993 Dec;14(12):615. Unique Identifier : AIDSLINE MED/94137365; Kennedy JR
Regression in basal cell carcinoma: an immunohistochemical analysis.: Br J Dermatol. 1994 Jan;130(1):1-8. Unique Identifier : AIDSLINE MED/94137569; Hunt MJ; Halliday GM; Weedon D; Cooke BE; Barnetson RS; Department of Dermatology, Royal Prince Alfred Hospital, Sydney,; Australia.; Spontaneous regression of some cutaneous tumours is well recognized, and is thought to result from an immunological response to the tumour. Regression has previously been noted in basal cell carcinomas, but no studies defining the role of the immune response in the regression of this malignancy have been performed. We
Emerging patterns of heterosexual HIV infection and transmission. Conference report.: Int J STD AIDS. 1993 Nov-Dec;4(6):348-52. Unique Identifier : AIDSLINE MED/94137872; Fraser PA; Phillips A; Leeds General Infirmary, West Yorkshire, UK.
Bronchoalveolar lavage fluid profiles in sarcoidosis, tuberculosis, and non-Hodgkin's and Hodgkin's disease. An evaluation of differences.: Chest. 1994 Feb;105(2):514-9. Unique Identifier : AIDSLINE MED/94139413; Drent M; Wagenaar SS; Mulder PH; van Velzen-Blad H; Diamant M; van den Bosch JM; Department of Pulmonary Diseases, St. Antonius Hospital,; Nieuwegein, The Netherlands.; The aim of this study was to identify characteristic features in bronchoalveolar lavage fluid (BALF) samples of patients with tuberculosis, non-Hodgkin s or Hodgkin s disease and to investigate whether these differences facilitate the distinction of those disorders from sarcoidosis presenting with a similar clinical p
Central nervous system toxoplasmosis in HIV-1 infected patients with persistently normal CD4+ cell counts [letter]: Eur J Clin Microbiol Infect Dis. 1993 Oct;12(10):787. Unique Identifier : AIDSLINE MED/94139771; Gervasoni C; Bini T; Franzetti F; Ridolfo AL; d'Arminio Monforte A
Serum measurements of soluble CD23 in HIV infection.: Immunology. 1993 Dec;80(4):652-3. Unique Identifier : AIDSLINE MED/94140421; Bansal AS; Pumphrey RS; Mandal BK; Khoo SH; Wilson PB; Regional Immunology Service Manchester Central Hospital.; A gradual reduction in cell-mediated immunity is thought to occur with the progression of human immunodeficiency virus (HIV) infection. This suggests a selective attrition of the Th1 subset. The regulation of the soluble form of the low-affinity receptor for IgE (sCD23) by the opposing actions of interleukin-4 (IL-4)
The simian immunodeficiency virus Nef protein promotes degradation of CD4 in human T cells.: J Biol Chem. 1994 Feb 11;269(6):3917-20. Unique Identifier : AIDSLINE MED/94140797; Sanfridson A; Cullen BR; Doyle C; Department of Immunology, Duke University Medical Center, Durham,; North Carolina 27710.; Expression of the Nef protein encoded by human and simian immunodeficiency viruses results in the specific down-regulation of CD4 from the cell surface in both lymphoid and non-lymphoid cells. In this report, we examine the biosynthesis and cell surface expression of CD4 in the human T cell line, CEM-SS, that has been
HIV testing and blood recipients [letter; comment] [see comments]: Lancet. 1994 Feb 19;343(8895):478. Unique Identifier : AIDSLINE MED/94142443; McMenamin JJ; Goldberg DJ; Green ST; McClelland B; Gillon J
High-purity factor concentrates in prevention of AIDS [letter; comment]: Lancet. 1994 Feb 19;343(8895):478-9. Unique Identifier : AIDSLINE MED/94142444; Schwarz HP; Kunschak M; Engl W; Eibl J
Aetiology of HIV-associated thrombocytopenia [letter; comment]: Lancet. 1994 Feb 19;343(8895):479. Unique Identifier : AIDSLINE MED/94142445; Behr T; Bair HJ; Becker W; Wolf F; Schwab J
Extending public health surveillance of HIV infection: information from a five cohort workshop. MAP Workshop (Multi-cohort Analysis Project).: Stat Med. 1993 Nov 30;12(22):2065-85. Unique Identifier : AIDSLINE MED/94143612
Markers as time-dependent covariates in relative risk regression. MAP Workshop (Multi-cohort Analysis Project).: Stat Med. 1993 Nov 30;12(22):2087-98. Unique Identifier : AIDSLINE MED/94143613
Marker paths. MAP Workshop (Multi-cohort Analysis Project).: Stat Med. 1993 Nov 30;12(22):2099-126. Unique Identifier : AIDSLINE MED/94143614
Markov models. MAP Workshop (Multi-cohort Analysis Project).: Stat Med. 1993 Nov 30;12(22):2127-30. Unique Identifier : AIDSLINE MED/94143615
Tracking of markers and onset of disease among HIV-1 seroconverters.: Stat Med. 1993 Nov 30;12(22):2133-45. Unique Identifier : AIDSLINE MED/94143616; Galai N; Munoz A; Chen K; Carey VJ; Chmiel J; Zhou SY; Department of Epidemiology, Johns Hopkins School of Hygiene and; Public Health, Baltimore, MD 21205.; Repeated measurements on persons infected with HIV-1 indicate that infection has a dynamic impact on several markers of immune suppression and activation. The objectives of this report are: (a) to provide a statistical model for the correlation structure of serial measurements of immunological markers, and (b) to iden
Prolonged neuromuscular blockade after a single bolus dose of vecuronium in patients with acquired immunodeficiency syndrome.: Anesthesiology. 1994 Feb;80(2):457-9. Unique Identifier : AIDSLINE MED/94144929; Fassoulaki A; Desmonts JM; Department of Anesthesia and Surgical Intensive Care, Hopital; Bichat, Universite, Paris, France.
Cytokines from vaccine-induced HIV-1 specific cytotoxic T lymphocytes: effects on viral replication.: AIDS Res Hum Retroviruses. 1993 Nov;9(11):1067-77. Unique Identifier : AIDSLINE MED/94145740; Bollinger RC; Quinn TC; Liu AY; Stanhope PE; Hammond SA; Viveen R; Clements ML; Siliciano RF; Department of Medicine, Johns Hopkins University School of; Medicine, Baltimore, Maryland 21205.; Cytolytic T lymphocytes (CTLs) specific for the human immunodeficiency virus (HIV-1) envelope glycoproteins have been cloned from HIV-1-seronegative human volunteers immunized with HIV-1 gp160-based candidate vaccines. Although vaccine-induced CTLs can potentially contribute to the antiviral response by direct lysis o
HIV gene expression enhances T cell susceptibility to hydrogen peroxide-induced apoptosis.: AIDS Res Hum Retroviruses. 1993 Nov;9(11):1107-13. Unique Identifier : AIDSLINE MED/94145745; Sandstrom PA; Roberts B; Folks TM; Buttke TM; Department of Microbiology and Immunology, East Carolina; University, School of Medicine, Greenville, North Carolina 27858.; A human T cell lineage was used to determine the possible effects of HIV infection on T cell antioxidant status. On inoculation into serum-free culture, 8E5, a constitutive HIV-expressing T cell line, underwent apoptosis whereas cell death was not observed with the uninfected A3.01 or latently HIV-infected 8E5L T cell
Influence of physiological concentration of progesterone on CD(4+)- and CD(8+)-activated lymphocytes with interleukin 2 and autologous plasma: difference between healthy donors and patients bearing malignant tumors.: Cancer Lett. 1993 Dec 20;75(3):157-65. Unique Identifier : AIDSLINE MED/94147372; Kimoto Y; Tong FZ; Taguchi T; Department of Oncologic Surgery, Osaka University, Japan.; The influence of progesterone at the physiological concentration on normal donor and malignant patient peripheral blood lymphocytes incubated with interleukin 2 ( IL-2 ) was investigated. Analysis of the phenotypes of IL-2-activated lymphocytes revealed that there was a
Provirus load changes in untreated and zidovudine-treated human immunodeficiency virus type 1-infected patients.: J Infect Dis. 1994 Feb;169(2):267-73. Unique Identifier : AIDSLINE MED/94149309; Luque F; Caruz A; Pineda JA; Torres Y; Larder B; Leal M; Department of Biochemistry and Internal Medicine, Virgen del; Rocio Universitary Hospital, Seville, Spain.; Human immunodeficiency virus type 1 (HIV-1) provirus burden was quantified during follow-up of untreated patients and mathematically analyzed by a parameter called intrinsic rate of increase (r). There was an increase in provirus burden in patients at early stages of the infection, and the increase occurred at a simil
Strain specificity of cell-mediated cytotoxic responses specific for the human immunodeficiency virus type 1 (HIV-1) envelope protein in seropositive donors: HIV-1Lai is more commonly recognized than HIV-1MN.: J Infect Dis. 1994 Feb;169(2):274-80. Unique Identifier : AIDSLINE MED/94149310; Robertson MN; Buseyne F; Kieny MP; Riviere Y; Unite de Virologie et Immunologie Cellulaire, Institut Pasteur,; Paris, France.; Cell-mediated cytotoxic (CMC) responses were measured in a group of human immunodeficiency virus type 1 (HIV-1)-seropositive donors against target cells expressing the envelope protein of either the HIV-1 strain Lai or strain MN. In primary CMC assays using freshly isolated peripheral blood mononuclear cells, seroposi
Mycobacterium avium complex in the respiratory or gastrointestinal tract and the risk of M. avium complex bacteremia in patients with human immunodeficiency virus infection.: J Infect Dis. 1994 Feb;169(2):289-95. Unique Identifier : AIDSLINE MED/94149312; Chin DP; Hopewell PC; Yajko DM; Vittinghoff E; Horsburgh CR Jr; Hadley WK; Stone EN; Nassos PS; Ostroff SM; Jacobson MA; et al; San Francisco General Hospital Medical Center, CA 94110.; Mycobacterium avium complex (MAC) is frequently isolated from the respiratory or gastrointestinal tract of patients with advanced human immunodeficiency virus (HIV) infection. Whether they are at increased risk of MAC bacteremia and whether culture of respiratory tract or stool specimens is useful for predicting bacte
Infection with human immunodeficiency virus type 1 (HIV-1) and human T cell lymphotropic viruses among leprosy patients and contacts: correlation between HIV-1 cross-reactivity and antibodies to lipoarabinomannan [see comments]: J Infect Dis. 1994 Feb;169(2):296-304. Unique Identifier : AIDSLINE MED/94149313; Kashala O; Marlink R; Ilunga M; Diese M; Gormus B; Xu K; Mukeba P; Kasongo K; Essex M; Department of Cancer Biology, Harvard School of Public Health,; Boston, Massachusetts 02115.; To determine the association between leprosy and human retroviral infections, 57 leprosy patients, 39 leprosy contacts, and 500 pregnant women were investigated serologically for antibodies to human immunodeficiency virus type 1 (HIV) and human T cell lymphotropic virus (HTLV) types I and II. Antibodies to Mycobacteri
Quantitation of human immunodeficiency virus by culture and polymerase chain reaction in response to didanosine after long-term therapy with zidovudine.: J Infect Dis. 1994 Feb;169(2):416-9. Unique Identifier : AIDSLINE MED/94149331; Katzenstein DA; Winters M; Bubp J; Israelski D; Winger E; Merigan TC; Center for AIDS Research, Stanford University Medical Center,; California.; Measurements of human immunodeficiency virus by quantitative RNA and DNA polymerase chain reaction (PCR), cell and plasma infectivity dilution cultures, and immune complex-disassociated p24 antigen-capture ELISA were made repeatedly in 10 subjects receiving long-term zidovudine treatment before and after therapy was c
Serum levels of tumor necrosis factor-alpha (TNF alpha) and soluble TNF receptors in human immunodeficiency virus type 1 infection--correlations to clinical, immunologic, and virologic parameters [published erratum appears in J Infect Dis 1994 May;169(5):1186-7]: J Infect Dis. 1994 Feb;169(2):420-4. Unique Identifier : AIDSLINE MED/94149332; Aukrust P; Liabakk NB; Muller F; Lien E; Espevik T; Froland SS; Section of Clinical Immunology and Infectious Diseases, Medical; Department A, Rikshospitalet, Oslo, Norway.; Two EIAs (Medgenix and Quantikine) and a bioassay were used to measure tumor necrosis factor-alpha (TNF alpha) in serum samples from 73 human immunodeficiency virus type 1 (HIV-1)-seropositive patients and in samples from 2 control groups. All clinical groups of HIV-1-infected patients, regardless of concurrent illnes
Improved cell-mediated immune responses in HIV-1-infected asymptomatic individuals after immunization with envelope glycoprotein gp160.: J Acquir Immune Defic Syndr. 1994 Mar;7(3):220-9. Unique Identifier : AIDSLINE MED/94149555; Wahren B; Bratt G; Persson C; Leven B; Hinkula J; Gilljam G; Nordlund S; Eriksson L; Volvovitz F; Broliden PA; et al; Department of Virology, South Hospital, Stockholm, Sweden.; Strong specific T-cell responses to human immunodeficiency virus type 1 (HIV-1) gp160 were induced by immunization with recombinant gp160 (rgp160). It was given as postinfection vaccination to 40 asymptomatic HIV-1 seropositive patients. The participants received 6 doses of 160 micrograms rgp160 administered intramusc
Germinal centre destruction as a major pathway of HIV pathogenesis.: J Acquir Immune Defic Syndr. 1994 Mar;7(3):236-44. Unique Identifier : AIDSLINE MED/94149557; Frost SD; McLean AR; Department of Zoology, University of Oxford, United Kingdom.; Human immunodeficiency virus (HIV)-induced destruction of follicular dendritic cells (FDCs), which are important in immunological memory, may be a major pathway of HIV pathogenesis. We use a mathematical model to investigate this hypothesis and conclude that a low level of FDC destruction could ultimately result in lo
Downregulation of CD28 surface antigen on CD4+ and CD8+ T lymphocytes during HIV-1 infection.: J Acquir Immune Defic Syndr. 1994 Mar;7(3):245-53. Unique Identifier : AIDSLINE MED/94149558; Choremi-Papadopoulou H; Viglis V; Gargalianos P; Kordossis T; Iniotaki-Theodoraki A; Kosmidis J; Dept of Immunology, Laiko General Hospital, Athens, Greece.; A progressive significant decrease of CD28 surface antigen expression on CD4+ (mean, 90, 86, 79, 68% in stages I, II, III, and IV, respectively, versus 96% in normals), as well as on CD8+ T lymphocytes (mean, 38, 32, 31, and 29% in stages I, II, III, and IV, respectively, versus 47% in normals) was observed during HIV
Quantitative anti-p24 determinations can predict the risk of vertical transmission. Swiss HIV and Pregnancy Collaborative Study Group.: J Acquir Immune Defic Syndr. 1994 Mar;7(3):261-4. Unique Identifier : AIDSLINE MED/94149560; Erb P; Krauchi S; Burgin D; Biedermann K; Camli C; Rudin C; Institute for Medical Microbiology, University of Basel,; Switzerland.; Quantitative serum antibody to p24 was evaluated as a predictor of risk of vertical transmission of human immunodeficiency virus type 1 (HIV-1) infection. HIV-positive mothers, 13 with HIV-infected children and 24 with noninfected children were investigated during pregnancy and at the time of delivery. A statistically
Intrathecal IgG synthesis and albumin leakage are increased in subjects with HIV-1 neurologic disease.: J Acquir Immune Defic Syndr. 1994 Mar;7(3):265-71. Unique Identifier : AIDSLINE MED/94149561; Singer EJ; Syndulko K; Fahy-Chandon B; Schmid P; Conrad A; Tourtellotte WW; Neurology and Research Services, VAMC West Los Angeles 90073.; We analyzed matched cerebrospinal fluid and blood samples from 139 subjects enrolled in a study of the effects of human immunodeficiency virus type 1 (HIV-1) on the nervous system. Mean total intrathecal IgG synthesis rate was significantly higher in subjects with HIV-1-related neurologic disease (NeuroPos) than in HI
Translational frameshifting at the gag-pol junction of human immunodeficiency virus type 1 is not increased in infected T-lymphoid cells.: J Virol. 1994 Mar;68(3):1501-8. Unique Identifier : AIDSLINE MED/94149839; Cassan M; Delaunay N; Vaquero C; Rousset JP; Institut de Genetique et Microbiologie, Universite Paris XI,; France.; A frameshift event is necessary for expression of the products of the pol gene in a number of retroviruses, including human immunodeficiency virus type 1 (HIV-1). The basic signals necessary for frameshifting consist of a shifty sequence in which the ribosome slips and a downstream stimulatory structure which can be e
Induction of HLA class I and class II expression in human T-lymphotropic virus type I-infected neuroblastoma cells.: J Virol. 1994 Mar;68(3):1854-63. Unique Identifier : AIDSLINE MED/94149881; Lehky TJ; Cowan EP; Lampson LA; Jacobson S; Neuroimmunology Branch, NINDS, NIH, Bethesda, MD 20892.; Human T-lymphotropic virus type I (HTLV-I) is associated with a neurologic disease, HTLV-I-associated myelopathy-tropical spastic paraparesis, in which both pathological and immunological changes are observed within the central nervous system. The pathogenesis of infection in HTLV-I-associated myopathy-tropical spasti
The phorbol ester phorbol myristate acetate inhibits human immunodeficiency virus type 1 envelope-mediated fusion by modulating an accessory component(s) in CD4-expressing cells.: J Virol. 1994 Mar;68(3):1962-9. Unique Identifier : AIDSLINE MED/94149892; Golding H; Manischewitz J; Vujcic L; Blumenthal R; Dimitrov DS; Division of Virology, CBER, Food and Drug Administration,; Bethesda, Maryland 20892.; The phorbol ester phorbol myristate acetate (PMA) strongly inhibits human immunodeficiency virus type 1 (HIV-1)-induced syncytium formation; it has been suggested that this inhibitory effect is due to the transient downmodulation of the surface-associated CD4 receptors by PMA (I. H. Chowdhury, Y. Koyanagi, S. Kobayash
Human herpesvirus 6 in AIDS [comment]: Lancet. 1994 Mar 5;343(8897):555-6. Unique Identifier : AIDSLINE MED/94150166; Lusso P; Gallo RC; Laboratory of Tumor Cell Biology, National Cancer Institute,; Bethesda, Maryland.
Disseminated active HHV-6 infections in patients with AIDS [see comments]: Lancet. 1994 Mar 5;343(8897):577-8. Unique Identifier : AIDSLINE MED/94150175; Knox KK; Carrigan DR; Department of Pathology, Medical College of Wisconsin, Milwaukee; 53226.; Human herpesvirus 6 (HHV-6) infected cells were detected in all lung, lymph-node, spleen, liver, and kidney tissues obtained at necropsy from an unselected series of nine patients with AIDS. This infection rate was significantly higher than that for cytomegalovirus . Lung infection
Vaccine-associated poliomyelitis [letter]: Lancet. 1994 Mar 5;343(8897):610-1. Unique Identifier : AIDSLINE MED/94150215; Arya SC
Trypsin in poliovaccine manufacture [letter; comment]: Lancet. 1994 Mar 5;343(8897):611. Unique Identifier : AIDSLINE MED/94150217; Hayflick L
A comparative trial of didanosine or zalcitabine after treatment with zidovudine in patients with human immunodeficiency virus infection. The Terry Beirn Community Programs for Clinical Research on AIDS [see comments]: N Engl J Med. 1994 Mar 10;330(10):657-62. Unique Identifier : AIDSLINE MED/94150516; Abrams DI; Goldman AI; Launer C; Korvick JA; Neaton JD; Crane LR; Grodesky M; Wakefield S; Muth K; Kornegay S; et al; San Francisco Community Consortium on AIDS, University of; California.; BACKGROUND. Both didanosine and zalcitabine are commonly used to treat patients with human immunodeficiency virus (HIV) infection who cannot tolerate zidovudine treatment or who have had disease progression despite it. The relative efficacy and safety of these second-line therapies are not well defined. METHODS. In th
Evaluation of the quality of life associated with zidovudine treatment in asymptomatic human immunodeficiency virus infection. The AIDS Clinical Trials Group [see comments]: N Engl J Med. 1994 Mar 17;330(11):738-43. Unique Identifier : AIDSLINE MED/94150546; Lenderking WR; Gelber RD; Cotton DJ; Cole BF; Goldhirsch A; Volberding PA; Testa MA; Statistical and Data Analysis Center, Harvard School of Public; Health, Boston, MA 02115.; BACKGROUND. Zidovudine therapy is recommended for asymptomatic patients infected with the human immunodeficiency virus (HIV) who have fewer than 500 CD4+ cells per cubic millimeter. An analysis of the quality of life associated with therapy that integrated both the effects of adverse events and the benefits of delayed
Polyarteritis nodosa in a patient with AIDS.: Neth J Med. 1993 Dec;43(5-6):215-7. Unique Identifier : AIDSLINE MED/94150770; Borleffs JC; Lamme TM; Beek FJ; Kater L; Department of Internal Medicine, University Hospital, Utrecht,; Netherlands.; A 33-year-old male homosexual with the acquired immunodeficiency syndrome (AIDS) presented with pain, blue colouring and ulceration of fingers and toes. Angiography of the superior mesenteric artery and renal arteries showed vessel wall irregularities and aneurysms, characteristic of polyarteritis nodosa (PAN). We des
Combinatorially selected guanosine-quartet structure is a potent inhibitor of human immunodeficiency virus envelope-mediated cell fusion.: Proc Natl Acad Sci U S A. 1994 Feb 15;91(4):1356-60. Unique Identifier : AIDSLINE MED/94151329; Wyatt JR; Vickers TA; Roberson JL; Buckheit RW Jr; Klimkait T; DeBaets E; Davis PW; Rayner B; Imbach JL; Ecker DJ; ISIS Pharmaceuticals, Carlsbad, CA 92008.; The phosphorothioate oligonucleotide T2G4T2 was identified as an inhibitor of HIV infection in vitro by combinatorial screening of a library of phosphorothioate oligonucleotides that contained all possible octanucleotide sequences. The oligonucleotide forms a parallel-stranded tetrameric guanosine-quartet structure. T
Analysis of the T-cell receptor beta-chain variable-region (V beta) repertoire in monozygotic twins discordant for human immunodeficiency virus: evidence for perturbations of specific V beta segments in CD4+ T cells of the virus-positive twins.: Proc Natl Acad Sci U S A. 1994 Feb 15;91(4):1529-33. Unique Identifier : AIDSLINE MED/94151363; Rebai N; Pantaleo G; Demarest JF; Ciurli C; Soudeyns H; Adelsberger JW; Vaccarezza M; Walker RE; Sekaly RP; Fauci AS; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, MD; 20892.; We analyzed the T-cell receptor (TCR) V beta repertoire in human immunodeficiency virus type 1 (HIV-1)-infected individuals at different stages of disease. To circumvent the effect of HLA and other loci on the expressed TCR repertoire, we compared the TCR repertoire in nine pairs of monozygotic twins who were discorda
[Asthenic disorders in persons infected with HIV at the initial stages of the disease]: Ter Arkh. 1993;65(11):26-8. Unique Identifier : AIDSLINE MED/94151749; Ruchkina EV; Beliaeva VV; Pokrovskii VV; Clinical psychopathological, follow-up and neuropsychological evaluation was made for 125 HIV-infected patients in stage 2B of the disease (general lymphadenopathy by V. I. Pokrovskii s classification). It is shown that seropositive subjects had asthenic syndrome for the initial 6 months of the disease. According to t
[An unusual variant of secondary recurrent syphilis in an HIV-infected patient]: Ter Arkh. 1993;65(11):28-9. Unique Identifier : AIDSLINE MED/94151750; Potekaev NS; Potekaev SN; Gorbacheva ES; Asymptomatic syphilis eventually manifesting with symptoms of the secondary disease was observed in a male with HIV-infection. Large focuses of alopecia reported in this male are suggested as a clinical marker of HIV-infection. A defective antibody response to T. pallidum in HIV-infection has been confirmed. Levomycet
Speculations around the mechanism behind the action of peptide T in the healing of psoriasis: a minireview.: Acta Derm Venereol. 1993 Dec;73(6):401-3. Unique Identifier : AIDSLINE MED/94152177; Johansson O; Hilliges M; Talme T; Marcusson JA; Wetterberg L; Department of Histology and Neurobiology, Karolinska Institute,; Stockholm, Sweden.; Peptide T, the HIV envelope-derived fragment Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr, has already been used to successfully treat psoriatic patients without major side-effects. The underlying reason for the positive effect is, however, at present unknown. In the following minireview, we summarize today s knowledge regarding p
Demodex-attributed rosacea-like lesions in AIDS.: Acta Derm Venereol. 1993 Dec;73(6):437. Unique Identifier : AIDSLINE MED/94152187; Redondo Mateo J; Soto Guzman O; Fernandez Rubio E; Dominguez Franjo F; Department of Internal Medicine, Dermatology and Pathologic; Anatomy, General Hospital of Segovia, Spain.; The association between AIDS and demodicidosis has been occasionally described elsewhere. We present a new case, in a patient with post-transfusional AIDS, who had many papules and pustules localized to the upper trunk and face, in relation to zidovudine treatment.
Long-latency event-related potentials in asymptomatic human immunodeficiency virus type 1 infection.: Ann Neurol. 1994 Feb;35(2):189-96. Unique Identifier : AIDSLINE MED/94153003; Connolly S; Manji H; McAllister RH; Fell M; Loveday C; Kirkis C; Herns M; Sweeney B; Sartawi O; Durrance P; et al; Department of Clinical Neurophysiology, University College London; Medical School, Middlesex Hospital, England.; As part of the Medical Research Council prospective study of the neurological and neuropsychological complications of human immunodeficiency virus (HIV) infection, long-latency event-related potentials were recorded in a cohort of homosexual and bisexual men. The latencies and amplitudes of the potentials, recorded fr
HIV1 integrase expressed in Escherichia coli from a synthetic gene.: Gene. 1993 Dec 22;136(1-2):323-8. Unique Identifier : AIDSLINE GENBANK/L24529; Holler TP; Foltin SK; Ye QZ; Hupe DJ; Department of Biochemistry, Parke-Davis Pharmaceutical Research,; Division of Warner-Lambert Company, Ann Arbor, MI 48105.; Human immunodeficiency virus type 1 (HIV1) integrase is cleaved from the gag-pol precursor by the HIV1 protease. The resulting 32-kDa protein is used by the infecting virus to insert a linear, double-stranded DNA copy of its genome, prepared by reverse transcription of viral RNA, into the host cell s chromosomal DNA.
Esophageal infections: risk factors, presentation, diagnosis, and treatment [see comments]: Gastroenterology. 1994 Feb;106(2):509-32. Unique Identifier : AIDSLINE MED/94131251; Baehr PH; McDonald GB; Gastroenterology/Hepatology Section, Fred Hutchinson Cancer; Research Center, Seattle, Washington.; Infections of the esophagus are unusual in the general population and strongly imply immunodeficiency, although immunocompetent individuals are not exempt. HIV infection is predominant among risk factors for infectious esophagitis. For all immunocompromised patients, the most frequently identified esophageal pathogens
Anal warts and squamous carcinoma-in-situ of the anal canal [see comments]: J R Soc Med. 1994 Jan;87(1):15. Unique Identifier : AIDSLINE MED/94141844; Morgan AR; Miles AJ; Wastell C; Department of Surgery, Chelsea and Westminster Hospital, London,; UK.
The price of institutional hype--lessons from the debate over AIDS combination-drug therapies.: Trends Biotechnol. 1993 Dec;11(12):489-91. Unique Identifier : AIDSLINE MED/94145606; Rotherberg L
A review of sexual behavior in the United States [see comments]: Am J Psychiatry. 1994 Mar;151(3):330-41. Unique Identifier : AIDSLINE MED/94152714; Seidman SN; Rieder RO; Department of Psychiatry, College of Physicians and Surgeons,; Columbia University, New York, NY 10032.; OBJECTIVE: Knowledge of sexual behavior in the United States is necessary for 1) directing risk-reduction interventions aimed at preventing transmission of human immunodeficiency virus (HIV) and other sexually transmitted pathogens and 2) appreciating the current normative patterns of
Fatal acute hepatic necrosis due to fluconazole [see comments]: Am J Med. 1994 Feb;96(2):188-90. Unique Identifier : AIDSLINE MED/94152677; Jacobson MA; Hanks DK; Ferrell LD; University of California, San Francisco.
Combined antineoplastic and antiretroviral therapy for patients with Hodgkin's disease and human immunodeficiency virus infection. A prospective study of 17 patients. The Italian Cooperative Group on AIDS and Tumors (GICAT).: Cancer. 1994 Jan 15;73(2):437-44. Unique Identifier : AIDSLINE MED/94123248; Errante D; Tirelli U; Gastaldi R; Milo D; Nosari AM; Rossi G; Fiorentini G; Carbone A; Vaccher E; Monfardini S; Division of Medical Oncology, Centro di Riferimento Oncologico,; Aviano, Italy.; BACKGROUND. The optimal therapeutic approach for patients with Hodgkin s disease (HD) and human immunodeficiency virus (HIV) infection is unknown. In an attempt to improve the results obtained with standard chemotherapy and to decrease the occurrence of opportunistic infections (OI) during chemotherapy and follow-up o
Steady-state kinetic studies with the polysulfonate U-9843, an HIV reverse transcriptase inhibitor.: Experientia. 1994 Jan 15;50(1):23-8. Unique Identifier : AIDSLINE MED/94123748; Althaus IW; Chou JJ; Gonzales AJ; LeMay RJ; Deibel MR; Chou KC; Kezdy FJ; Romero DL; Thomas RC; Aristoff PA; et al; Upjohn Company, Kalamazoo, Michigan 49001.; The tetramer of ethylenesulfonic acid (U-9843) is a potent inhibitor of HIV-1 RT* and possesses excellent antiviral activity at nontoxic doses in HIV-1 infected lymphocytes grown in tissue culture. Kinetic studies of the HIV-1 RT-catalyzed RNA-directed DNA polymerase activity were carried out in order to determine if
Folding patterns of immunoglobulin molecules identified by urea gradient electrophoresis.: J Biol Chem. 1994 Jan 21;269(3):1834-8. Unique Identifier : AIDSLINE MED/94124526; Attanasio R; Stunz GW; Kennedy RC; Department of Virology and Immunology, Southwest Foundation for; Biomedical Research, San Antonio, Texas 78228-0147.; The reversible denaturant-induced unfolding of immunoglobulin molecules has been analyzed by transverse urea gradient gel electrophoresis and the effects that urea-induced unfolding exerts on the functional properties associated with their variable region, i.e. antigen binding and idiotypic expression, have been deter
Hepatitis C virus infection in anti-HIV positive and negative French homosexual men with chronic hepatitis: comparison of second- and third-generation anti-HCV testing.: Liver. 1993 Dec;13(6):319-22. Unique Identifier : AIDSLINE MED/94125904; Marcellin P; Colin JF; Martinot-Peignoux M; Pham BN; Lefort V; Picault AB; Degott C; Erlinger S; Benhamou JP; Service d'Hepatologie, Hopital Beaujon, Clichy, France.; To determine the prevalence of hepatitis C virus (HCV) infection in homosexuals with chronic hepatitis, we tested for anti-HCV antibodies 113 (47 anti-HIV positive) French non-drug-addicted homosexual men admitted for chronic viral hepatitis. Anti-HCV were detected with second- and third-generation ELISAs (ELISA2 and
Hepatitis C virus seroprevalence in patients attending a sexual health centre.: N Z Med J. 1994 Jan 26;107(970):8-10. Unique Identifier : AIDSLINE MED/94126230; McKenna JG; Evans G; Lyttle PH; Couper A; Sexual Health Centre, Christchurch Hospital.; AIM. To determine the prevalence of hepatitis C virus (HCV) infection in patients attending the Christchurch sexual health centre. METHODS. Anonymised unlinked serum specimens from 362 patients sequentially attending the sexual health centre were obtained and tested for HCV antibody using the second generation enzyme
Population dynamics of CD4+ T cells lacking Thy-1 in murine retrovirus-induced immunodeficiency syndrome (MAIDS).: Scand J Immunol. 1994 Feb;39(2):216-24. Unique Identifier : AIDSLINE MED/94126672; Moutschen MP; Colombi S; Deprez M; Van Wijk F; Hotermans C; Martin MT; Greimers R; Boniver J; Department of Pathology, University of Liege, Belgium.; Increased numbers of CD4+ Thy-1- cells have been described in the spleen (SP) of mice with retrovirus-induced immunodeficiency (MAIDS). Since this phenotypic abnormality might have considerable functional importance, the expansion of the CD4+ Thy-1- subset in MAIDS was characterized further. CD4+ Thy-1- and Thy-1+ T-c
Passively transferred antibodies directed against conserved regions of SIV envelope protect macaques from SIV infection.: Vaccine. 1993 Oct;11(13):1347-55. Unique Identifier : AIDSLINE MED/94127087; Lewis MG; Elkins WR; McCutchan FE; Benveniste RE; Lai CY; Montefiori DC; Burke DS; Eddy GA; Shafferman A; Henry M. Jackson Foundation Research Laboratory, Rockville, MD; 20852.; Inactivated plasma collected from either SIV-infected or peptide-vaccinated macaques was transferred into 17 naive rhesus monkeys. Two additional macaques received normal plasma and served as controls. Following transfer all 19 monkeys were inoculated with SIV. While the controls became infected and were virus-isolati
Human immunodeficiency virus type-1 reverse transcriptase and ribonuclease H as substrates of the viral protease.: Protein Sci. 1993 Dec;2(12):2167-76. Unique Identifier : AIDSLINE MED/94129399; Tomasselli AG; Sarcich JL; Barrett LJ; Reardon IM; Howe WJ; Evans DB; Sharma SK; Heinrikson RL; Biochemistry Unit, Upjohn Laboratories, Kalamazoo, Michigan; 49001.; A study has been made of the susceptibility of recombinant constructs of reverse transcriptase (RT) and ribonuclease H (RNase H) from human immunodeficiency virus type 1 (HIV-1) to digestion by the HIV-1 protease. At neutral pH, the protease attacks a single peptide bond, Phe440-Tyr441, in one of the protomers of the
The envelope glycoprotein of HIV-1 gp120 and human complement protein C1q bind to the same peptides derived from three different regions of gp41, the transmembrane glycoprotein of HIV-1, and share antigenic homology.: Eur J Immunol. 1994 Feb;24(2):294-300. Unique Identifier : AIDSLINE MED/94130941; Stoiber H; Thielens NM; Ebenbichler C; Arlaud GJ; Dierich MP; Institut fur Hygiene, Leopold-Franzens-University, Innsbruck,; Austria.; gp41, the transmembrane glycoprotein of HIV-1, has been shown to be non-covalently associated with gp120. We have shown that it also binds human C1q. To analyze the interaction site(s) of gp41 with these two molecules, we established an enzyme-linked immunosorbent assay (ELISA) system using recombinant soluble gp41 [a
A gene expression vector useful for protein purification and studies of protein-protein interaction.: Gene. 1993 Dec 31;137(2):345-6. Unique Identifier : AIDSLINE MED/94131309; Zhao LJ; Narayan O; Marion Merrell Dow Foundation, Department of Microbiology,; Molecular Genetics and Immunology, University of Kansas Medical; Center, Kansas City 66160-7424.; This report describes the development of a gene expression vector that adds three features to the C-terminus of the putative synthesized protein: (1) a protein kinase A recognition domain allowing the protein to be radio-labeled in vitro, (2) an epitope marker for immunocharacterization of the protein with a commercia
Interferon decreases serum lipid peroxidation products of hepatitis C patients.: Free Radic Biol Med. 1994 Jan;16(1):131-3. Unique Identifier : AIDSLINE MED/94131330; Higueras V; Raya A; Rodrigo JM; Serra MA; Roma J; Romero FJ; Department of Physiology, School of Medicine and Dentistry,; University of Valencia, Spain.; Thiobarbituric acid reactive substances (TBARS) concentration in serum has been determined in healthy subjects and in patients suffering acute hepatitis and chronic cases of hepatitis C. Treatment with interferon of the chronic active hepatitis C patients, 5 x 10(6) U three times a week during 2 months, led in those p
What's new in treatment?: J Clin Apheresis. 1993;8(3):168-73; discussion 181-6. Unique Identifier : AIDSLINE MED/94131982; Collier AC; AIDS Clinical Trials Unit, Harborview Medical Center, University; of Washington, Seattle.
Neutralization epitopes on HIV pseudotyped with HTLV-I: conservation of carbohydrate epitopes [published erratum appears in J Acquir Immune Defic Syndr 1994 Jul;7(7):740]: J Acquir Immune Defic Syndr. 1994 Feb;7(2):116-23. Unique Identifier : AIDSLINE MED/94133079; Sorensen AM; Nielsen C; Arendrup M; Clausen H; Nielsen JO; Osinaga E; Roseto A; Hansen JE; Department of Infectious Diseases, University of Copenhagen,; Hvidovre Hospital, Denmark.; One mechanism for expanding the cellular tropism of human immunodeficiency virus (HIV) in vitro is through formation of phenotypically mixed particles (pseudotypes) with human T lymphotropic virus type I (HTLV-I). In this study we found that pseudotypes allow penetration of HIV particles into CD4-negative cells, previ
Current perspectives on antiretroviral therapy.: Pharmacotherapy. 1993 Nov-Dec;13(6):627-33. Unique Identifier : AIDSLINE MED/94134526; Fletcher CV; Department of Pharmacy Practice, College of Pharmacy, University; of Minnesota, Minneapolis 55455.; Current estimates suggest that at least 1 million persons in the United States are infected with the human immunodeficiency virus (HIV), the cause of the acquired immunodeficiency syndrome. Knowledge of the life cycle of HIV has provided the fundamental information necessary to initiat
[HIV infections in children]: Soins Gynecol Obstet Pueric Pediatr. 1993 Jun-Jul;(145-6):7-12. Unique Identifier : AIDSLINE MED/94135568; Le Bont H
Interferon-gamma and kit ligand are primary regulators of GTP cyclohydrolase activity: mechanisms and implications.: Adv Exp Med Biol. 1993;338:211-6. Unique Identifier : AIDSLINE MED/94136222; Ziegler I; Schott K; Hultner L; GSF-Institut fur Klinische Molekularbiologie, Munchen.
HIV resistance to reverse transcriptase inhibitors.: Biochem Pharmacol. 1994 Jan 20;47(2):155-69. Unique Identifier : AIDSLINE MED/94137263; De Clercq E; Rega Institute for Medical Research, Katholieke Universiteit; Leuven, Belgium.
Urinary excretion of modified nucleosides as biological marker of RNA turnover in patients with cancer and AIDS.: Clin Chim Acta. 1993 Sep 30;218(2):169-83. Unique Identifier : AIDSLINE MED/94139052; Nakano K; Nakao T; Schram KH; Hammargren WM; McClure TD; Katz M; Petersen E; Life Science Division, Church of Perfect Liberty, Osaka, Japan.; Using boronate gel affinity chromatography and reversed-phase high-performance liquid chromatography (RP-HPLC), a method for the simultaneous determination of 12 urinary modified nucleosides has been developed. The RP-HPLC fractions were identified by gas chromatography/mass spectrometry analysis. The HPLC quantitatio
Specificity of priming reaction of HIV-1 reverse transcriptase, 2'-OH or 3'-OH.: J Biol Chem. 1994 Feb 11;269(6):3925-7. Unique Identifier : AIDSLINE MED/94140799; Shimada M; Hosaka H; Takaku H; Smith JS; Roth MJ; Inouye S; Inouye M; Department of Biochemistry, Robert Wood Johnson Medical School,; Piscataway, New Jersey 08854.; It has not been unambiguously demonstrated whether the priming reaction of human immunodeficiency virus, type 1 (HIV-1) cDNA synthesis initiates with either the 2 -OH or 3 -OH group of the 3 -terminal adenosine residue of tRNA(Lys-3). In this report, we synthesized tRNA(Lys-3) of which the 3 -terminal adenosine residu
Effect of a thiobenzimidazolone derivative on DNA strand transfer catalyzed by HIV-1 reverse transcriptase.: J Biol Chem. 1994 Feb 11;269(6):4110-5. Unique Identifier : AIDSLINE MED/94140828; Gopalakrishnan V; Benkovic S; Department of Chemistry, Pennsylvania State University,; University Park 16802.; Thiobenzimidazolone (TIBO) derivatives are known inhibitors of the DNA polymerase activity of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT). The effect of a TIBO derivative ((+)-S-4,5,6,7-tetrahydro-9-chloro-5- methyl-6-(3-methyl-2-butenyl)-imidazol[4,5,1-jk]1,4-benzodiazapin- e -2-thione ) on
A new trichrome-blue stain for detection of microsporidial species in urine, stool, and nasopharyngeal specimens.: J Clin Microbiol. 1993 Dec;31(12):3264-9. Unique Identifier : AIDSLINE MED/94141002; Ryan NJ; Sutherland G; Coughlan K; Globan M; Doultree J; Marshall J; Baird RW; Pedersen J; Dwyer B; Victorian Infectious Diseases Reference Laboratory, Fairfield; Hospital, Victoria, Australia.; Detection of microsporidia in clinical specimens has relied on electron microscopy, histology, or staining. This article describes further alterations to the modified trichrome staining method which make it easier to identify microsporidial spores. The changes are a decrease in the phosphotungstic acid level and the s
A novel in situ model to study Pneumocystis carinii adhesion to lung alveolar epithelial cells.: J Immunol Methods. 1994 Jan 3;167(1-2):161-71. Unique Identifier : AIDSLINE MED/94141191; Pavia-Ruz N; Ortega-Barria E; Alroy J; Pereira ME; Department of Medicine, New England Medical Center Hospitals,; Boston, MA 02111.; Pneumocystis carinii, an extracellular parasite thriving in the lungs of immunosuppressed mammals, is a major cause of death in AIDS patients in the USA. As a prelude to growth, the parasite adheres mostly to type I pneumocytes lining the alveolar spaces. The mechanism of adherence remains unknown, largely because of
Prevalence of antibody to hepatitis C virus (HCV) in HIV-1-infected patients (nice SEROCO cohort).: J Med Virol. 1994 Jan;42(1):29-32. Unique Identifier : AIDSLINE MED/94141475; Quaranta JF; Delaney SR; Alleman S; Cassuto JP; Dellamonica P; Allain JP; Service de Medecine Interne II, Hematologie, Hopital de; Cimiez, CHU Nice, France.; The prevalence of antibody to hepatitis C virus (HCV) in a cohort of 272 HIV-infected patients was assessed by means of 4 anti-HCV assays: a 1st generation and a neutralization test, a 2nd generation test, and a confirmatory test, the dot-blot Matrix HCV immunoassay. The cohort included, as a single risk factor, 35.7%
What don't you know about HIV?: J Calif Dent Assoc. 1993 Sep;21(9):15. Unique Identifier : AIDSLINE MED/94141502; Mulligan R
Improving HIV/AIDS care through education.: J Calif Dent Assoc. 1993 Sep;21(9):19-22. Unique Identifier : AIDSLINE MED/94141503; Gates JD; Aids Education and Training Center for Southern California, Los; Angeles 90033.; It is essential that primary healthcare providers, including dentists, be able to screen and counsel their patients for AIDS and exposure to HIV. This article reviews efforts of the AIDS Education and Training Center for Southern California to train healthcare providers.
The changing profile of the HIV/AIDS epidemic.: J Calif Dent Assoc. 1993 Sep;21(9):23-8. Unique Identifier : AIDSLINE MED/94141504; Mulligan R; Department of Dental Medicine and Public Health, USC School of; Dentistry, Los Angeles, CA 90089.; The HIV/AIDS epidemic has undergone significant changes in the population affected and the opportunistic infections most commonly seen since the disease was first identified. Dental care providers must be aware of the changing profile of this disease in order to provide adequate assessment and treatment of their patie
Viral pathogenesis and opportunistic infections.: J Calif Dent Assoc. 1993 Sep;21(9):29-36. Unique Identifier : AIDSLINE MED/94141505; Gupta G; UC Irvine Medical Center, Aids Education and Training Program,; Orange, California 92668.; Knowledge about the pathogenesis and management of HIV infection has increased dramatically over the last decades. Because of advances in drugs, diagnosis and management, HIV-infected patients are living longer. This paper provides current concepts of HIV pathogenesis and antiviral therapy, and an overview of AIDS-rel
Common oral lesions associated with HIV infection.: J Calif Dent Assoc. 1993 Sep;21(9):37-42. Unique Identifier : AIDSLINE MED/94141506; Navazesh M; Lucatorto F; Department of Dental Medicine and Public Health, USC School of; Dentistry, Los Angeles, CA 90089.; More than 40 different lesions involving head and neck areas have been associated with HIV infection. The oral cavity may manifest the first sign of HIV infection. Early detection of these conditions can lead to early diagnosis of HIV infection and subsequent appropriate management. Signs, symptoms and management of t
The dentist, HIV and the law: duty to treat, need to understand.: J Calif Dent Assoc. 1993 Sep;21(9):45-50. Unique Identifier : AIDSLINE MED/94141507; Schulman DI; AIDS/HIV Discrimination Unit, Los Angeles City Attorney's Office,; CA 90012.; An understanding of three areas of law--anti-discrimination, workplace safety and privacy and confidentiality--is helpful to dentists in meeting their responsibilities to treat HIV-infected individuals. This understanding also will assist in establishing a practice atmosphere in which HIV-infected patients will feel c
Artificial protein vaccines with predetermined tertiary structure: application to anti-HIV-1 vaccine design.: Protein Eng. 1993 Nov;6(8):997-1001. Unique Identifier : AIDSLINE MED/94143356; Eroshkin AM; Zhilkin PA; Shamin VV; Korolev S; Fedorov BB; Research Institute of Molecular Biology, NPO VECTOR, Koltsovo,; Novosibirsk Region, Russia.; A successful approach to the development of a safe and effective synthetic vaccine requires that different B and T cell epitopes of the infectious agent be included in the vaccine construction. In this paper we suggest a new approach to vaccine design in the form of an artificial protein with a predetermined tertiary
Differential antiviral activity of two TIBO derivatives against the human immunodeficiency and murine leukemia viruses alone and in combination with other anti-HIV agents.: AIDS Res Hum Retroviruses. 1993 Nov;9(11):1097-106. Unique Identifier : AIDSLINE MED/94145744; Buckheit RW Jr; Germany-Decker J; Hollingshead MG; Allen LB; Shannon WM; Janssen PA; Chirigos MA; Virology Research Division, Southern Research Institute-Frederick; Research Center, Maryland 21701.; R82913 and R86183, two derivatives of tetrahydroimidazo[4,5,1-jk][1,4]-benzodiazepin-2(1H)-thione (TIBO), were found to potently and selectively inhibit the replication and cell killing effects of a panel of biologically diverse laboratory and clinical strains of HIV-1. The two compounds exhibited significant activity
Neonatal disease induced by SIV infection of the rhesus monkey (Macaca mulatta).: AIDS Res Hum Retroviruses. 1993 Nov;9(11):1131-7. Unique Identifier : AIDSLINE MED/94145748; Bohm RP Jr; Martin LN; Davison-Fairburn B; Baskin GB; Murphey-Corb M; Department of Veterinary Sciences, Tulane Regional Primate; Research Center (TRPRC), Covington, Louisiana 70433.; Seven 72-hr-old Indian origin rhesus monkeys (Macaca mulatta) were inoculated with 10 animal ID50 of SIV/DeltaB670. Nine age-matched animals were used as uninoculated controls. All seven inoculated animals became infected as verified by viral isolation and SIV p26 antigenemia. Five of seven infected animals died withi
Treatment of bacterial, fungal, and parasitic infections in the HIV-infected host.: Semin Dermatol. 1993 Dec;12(4):296-300. Unique Identifier : AIDSLINE MED/94145862; Berger TG; Department of Dermatology, University of California, San; Francisco 94110.; In the human immunodeficiency virus (HIV) infected patient, skin infections caused by S aureus are extremely common. Impetigo, ecthyma, and folliculitis are all seen. Recurrences are common due to a nasal carriage rate of 50%. Dermatophytosis usually manifests as tinea pedis or unguium and is caused by Trichophyton ru
Catalytically distinct conformations of the ribonuclease H of HIV-1 reverse transcriptase by substrate cleavage patterns and inhibition by azidothymidylate and N-ethylmaleimide.: Biochemistry. 1994 Feb 15;33(6):1366-72. Unique Identifier : AIDSLINE MED/94145986; Zhan X; Tan CK; Scott WA; Mian AM; Downey KM; So AG; Department of Medicine, University of Miami School of Medicine,; Florida 33101.; The RNase H activity of recombinant HIV-1 reverse transcriptase (RT) has been characterized with respect to inhibition by azidothymidylate (AZTMP) and N-ethylmaleimide (NEM) and to cleavage patterns using either poly(rA)/poly(dT) or poly(rG)/poly(dC) as model substrate and either Mg2+ or Mn2+ as divalent cation activa
AIDS and HIV-1 infection in the United Kingdom: monthly report.: Commun Dis Rep CDR Wkly. 1993 Dec 17;3(51):235-6. Unique Identifier : AIDSLINE MED/94146890
HIV transmission between children at home.: Commun Dis Rep CDR Wkly. 1993 Dec 24;3(52):237. Unique Identifier : AIDSLINE MED/94146891
The infra-red coagulator in the treatment of AIDS-related Kaposi's sarcoma and a comparison with radiotherapy.: Clin Exp Dermatol. 1994 Jan;19(1):23-5. Unique Identifier : AIDSLINE MED/94147689; Langtry JA; Bottomley DM; Phillips RH; Staughton RC; Departments of Dermatology, Westminster Hospital, London, UK.; Experience with 1 s pulses of the infra-red coagulator is reported for the treatment of 10 cutaneous AIDS-related Kaposi s sarcoma lesions in seven patients. The infra-red coagulator may be a useful addition in the palliative cosmetic treatment of Kaposi s sarcoma, producing an acceptable result in small (less than 2
Transfusion-associated graft-versus-host disease--report of two further cases with an immunohistochemical analysis.: Clin Exp Dermatol. 1994 Jan;19(1):36-42. Unique Identifier : AIDSLINE MED/94147692; Arico M; Noto G; Pravata G; Bongiorno MR; Mirto S; Malizia G; Istituto di Dermatologia Sperimentale, University of Palermo,; Italy.; Transfusion-associated graft-vs.-host disease (tGVHD) is a severe disease usually affecting immunocompromised hosts with haematological neoplasia. Two patients with acute leukaemia are reported, who developed fatal tGVHD after blood transfusions. Intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molec
The number of CD1a+ large low-density cells with dendritic cell features is increased in the peripheral blood of HIV+ patients.: Clin Immunol Immunopathol. 1994 Mar;70(3):190-7. Unique Identifier : AIDSLINE MED/94147714; Ree HJ; Liau S; Yancovitz SR; Qureshi MN; Khan AA; Teplitz C; Beth Israel Medical Center, New York, New York 10003.; Employing a discontinuous Percoll gradient following Ficoll-Hypaque separation of peripheral blood mononuclear cells from normal subjects (n = 14) and patients with HIV-1 infection (n = 50), we separated a population of low-density cells consisting of monocytoid cells, lymphocytes, and some granulocytes. In cytospin p
Human T lymphocyte subpopulation and NK cell alterations in persons exposed to cocaine.: Clin Immunol Immunopathol. 1994 Mar;70(3):245-50. Unique Identifier : AIDSLINE MED/94147722; Ruiz P; Cleary T; Nassiri M; Steele B; University of Miami School of Medicine, Department of Pathology,; Florida 33101.; Immunophenotypic changes in peripheral blood mononuclear cells were analyzed by flow cytometry in several patient groups positive for cocaine in their urine. Single- and dual-color immunofluorescence staining was performed to examine total numbers of NK, T, and B cells, as well as the coexpression of surface molecules
Neurological dysfunction in asymptomatic HIV-1 infected men: evidence from evoked potentials. HNRC Group.: Electroencephalogr Clin Neurophysiol. 1994 Jan;92(1):1-10. Unique Identifier : AIDSLINE MED/94147952; Iragui VJ; Kalmijn J; Thal LJ; Grant I; Department of Neurosciences, University of California, San Diego; School of Medicine, La Jolla.; Neurological function in 159 subjects infected by the human immunodeficiency virus (HIV) who had no neurological symptoms or signs (129 asymptomatic, 30 with ARC/AIDS) was compared to that of 62 controls by means of pattern-reversal evoked potentials (PREPs), brain-stem auditory evoked potentials (BAEPs), median nerve
Binding of human immunodeficiency virus type-1 (HIV-1) to partially purified membrane vesicles of lymphoblastoid cell line CEM.: J Virol Methods. 1993 Dec 31;45(3):319-30. Unique Identifier : AIDSLINE MED/94149112; Benzair AB; Hirsch I; Chermann JC; Unite de Recherches INSERM sur les Retrovirus et Maladies; Associees (U.322), Campus Universitaire de Luminy, Marseille,; France.; Binding of human immunodeficiency virus type 1 (HIV-1) to membrane of its target cells was studied by a quantitative and non-isotopic method called the viral membrane trapping method (VMTM). Membranes prepared from the CD4 positive lymphoblastoid cell line CEM and adsorbed to a solid support retained the ability to bi
Anabolic effects of recombinant insulin-like growth factor-I in cachectic patients with the acquired immunodeficiency syndrome.: J Clin Endocrinol Metab. 1994 Feb;78(2):404-10. Unique Identifier : AIDSLINE MED/94149144; Lieberman SA; Butterfield GE; Harrison D; Hoffman AR; Medical Service, Department of Veterans Affairs Medical Center,; Palo Alto, California 94304.; The loss of lean body mass accompanying acquired immunodeficiency syndrome (AIDS)-associated cachexia is refractory to current modes of therapy. GH and insulin-like growth factor-I (IGF-I) stimulate protein accretion, but resistance to GH action has been reported in malnutrition and infection. We hypothesized that GH
Heat-shock proteins expressed on the surface of human T cell leukemia virus type I-infected cell lines induce autoantibodies in rabbits.: J Infect Dis. 1994 Feb;169(2):253-9. Unique Identifier : AIDSLINE MED/94149307; Chouchane L; Bowers FS; Sawasdikosol S; Simpson RM; Kindt TJ; Laboratory of Immunogenetics, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Rockville,; Maryland 20852.; Eight human T cell leukemia virus type I (HTLV-I)-infected cell lines were derived in vitro from peripheral blood mononuclear cells of 8 rabbits. Each rabbit was then inoculated with its own HTLV-I-transformed cells, after which all but 1 rabbit had anti-heat-shock protein (hsp) antibodies in sera. Cell line RH/K34, w
Sequence variation within the immunodominant epitope-coding region from the external glycoprotein of human T lymphotropic virus type II in isolates from Seminole Indians.: J Infect Dis. 1994 Feb;169(2):407-11. Unique Identifier : AIDSLINE MED/94149329; Lal RB; Owen SM; Rudoph D; Levine PH; Retrovirus Diseases Branch, Centers for Disease Control and; Prevention, Atlanta, Georgia 30329.; Western blot analysis of 16 serum specimens from Seminole Indians demonstrated that 14 reacted with the type-specific recombinant epitope (rgp46II+) of human T lymphotropic virus type II (HTLV-II), whereas the remaining 2 specimens did not (rgp46II-). Both rgp46II- specimens demonstrated presence of HTLV-II genome by
Heterosexual transmission of human immunodeficiency virus type 1 variants associated with zidovudine resistance.: J Infect Dis. 1994 Feb;169(2):411-5. Unique Identifier : AIDSLINE MED/94149330; Conlon CP; Klenerman P; Edwards A; Larder BA; Phillips RE; Infectious Diseases Unit, Nuffield Department of Clinical; Medicine, John Radcliffe Hospital, Oxford, United Kingdom.; During zidovudine therapy, human immunodeficiency virus type 1 (HIV-1) acquires a distinctive set of mutations that diminish the sensitivity of the virus to this drug in vitro. An AIDS patient is described who, while being treated with zidovudine, transmitted HIV-1 bearing a drug resistance mutation to a young woman w
Markers of hepatitis C virus infection in Sardinian blood donors: relationship with alanine aminotransferase levels.: J Med Virol. 1993 Dec;41(4):282-8. Unique Identifier : AIDSLINE MED/94149440; Lai ME; Mazzoleni AP; Farci P; Melis A; Porru A; Orgiana G; Arnone M; Balestrieri A; Department of Internal Medicine, University of Cagliari, Italy.; Serum samples from 1,765 consecutive Sardinian blood donors, negative for hepatitis B surface antigen (HBsAg) and for antibodies to human immunodeficiency virus (HIV) (anti-HIV), were evaluated for the presence of antibodies to hepatitis C virus (anti-HCV) by second-generation ELISA. Anti-HCV was detected in 25 (1.45%
Induction of IL-1 beta, IL-6, TNF-alpha, GM-CSF and G-CSF in human macrophages by smooth transparent and smooth opaque colonial variants of Mycobacterium avium.: J Med Microbiol. 1994 Feb;40(2):129-33. Unique Identifier : AIDSLINE MED/94149666; Fattorini L; Xiao Y; Li B; Santoro C; Ippoliti F; Orefici G; Laboratory of Bacteriology and Medical Mycology, Istituto; Superiore di Sanita, Rome, Italy.; Both smooth transparent (SmT) and smooth domed-opaque (SmD) colonial variants were obtained from a strain of Mycobacterium avium isolated from a patient with AIDS. The two variants showed similar biochemical characteristics but SmT bacteria proliferated better than SmD bacteria inside human macrophages and were much l
Studies on primer binding of HIV-1 reverse transcriptase using a fluorescent probe.: J Mol Biol. 1994 Feb 18;236(2):469-79. Unique Identifier : AIDSLINE MED/94149751; Delahunty MD; Wilson SH; Karpel RL; Department of Chemistry and Biochemistry, University of Maryland; Baltimore County 21228.; The fluorescent nucleotide analog, 2 ,3 -trinitrophenyladenosine-5 -triphosphate (TNP-ATP), was utilized to quantify the affinities of human immunodeficiency virus-1 reverse transcriptase (HIV-1 RT) for its substrates. Interaction of this probe with the enzyme brings about a twofold increase in the magnitude of fluore
Minimal sequence requirements of a functional human immunodeficiency virus type 1 primer binding site.: J Virol. 1994 Mar;68(3):1605-14. Unique Identifier : AIDSLINE MED/94149851; Wakefield JK; Rhim H; Morrow CD; Department of Microbiology, University of Alabama at Birmingham; 35294.; The initiation of human immunodeficiency virus type 1 (HIV-1) reverse transcription occurs by the extension of a tRNA(3Lys) primer bound near the 5 end of the genomic RNA at a position termed the primer binding site (PBS). The PBS is an 18-nucleotide sequence of the HIV-1 genome which is complementary to the 3 -termi
Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during therapy.: J Virol. 1994 Mar;68(3):1660-6. Unique Identifier : AIDSLINE MED/94149857; Richman DD; Havlir D; Corbeil J; Looney D; Ignacio C; Spector SA; Sullivan J; Cheeseman S; Barringer K; Pauletti D; et al; Department of Pathology, University of California, San Diego; 92093-0679.; Drug susceptibility and mutations in the reverse transcriptase (RT) gene were analyzed with 167 virus isolates from 38 patients treated with nevirapine , a potent nonnucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1) RT. Resistant isol
Redesignation of the RNase D activity associated with retroviral reverse transcriptase as RNase H.: J Virol. 1994 Mar;68(3):1970-1. Unique Identifier : AIDSLINE MED/94149893; Hostomsky Z; Hughes SH; Goff SP; Le Grice SF; Agouron Pharmaceuticals Inc., San Diego, California 92121.; In the presence of Mn2+, reverse transcriptase of both human immunodeficiency virus and murine leukemia virus hydrolyzes duplex RNA. However, designating this novel activity RNase D conflicts with Escherichia coli RNase D, which participates in tRNA processing. On the basis of its location in the RNase H domain, we pr
Functional role of the zipper motif region of human immunodeficiency virus type 1 transmembrane protein gp41.: J Virol. 1994 Mar;68(3):2002-10. Unique Identifier : AIDSLINE MED/94149900; Chen SS; Department of Pediatrics, Harvard Medical School, Boston,; Massachusetts.; To study the functional role of the zipper motif region, located in the N-terminal region of the envelope transmembrane protein of human immunodeficiency virus type 1, a series of vaccinia virus-expressed mutant proteins containing a proline substitution in this region were characterized. All of the mutant proteins sh
Prevalence of antibodies to hepatitis C virus in populations at low and high risk for sexually transmitted diseases in Rio de Janeiro.: Mem Inst Oswaldo Cruz. 1993 Apr-Jun;88(2):305-7. Unique Identifier : AIDSLINE MED/94150345; Edelenyi-Pinto M; Carvalho AP; Nogueira C; Ferreira Junior O; Schechter M; Laboratorio de Pesquisas do Programa SIDA/AIDS, Hospital; Universitario Clementino Fraga Filho, Rio de Janeiro, Brasil.; In order to investigate the sexual transmission of the Hepatitis C Virus (HCV), the prevalence of specific antibodies in populations at high and low risk for sexually transmitted diseases (STDs) was evaluated. The population at low risk for STDs was composed of persons who voluntarily donated blood at the Hospital Uni
Ultrasensitive retrovirus detection by a reverse transcriptase assay based on product enhancement.: Proc Natl Acad Sci U S A. 1994 Feb 15;91(4):1544-8. Unique Identifier : AIDSLINE MED/94151366; Pyra H; Boni J; Schupbach J; Swiss National Center for Retroviruses, Institute of Medical; Virology, University of Zurich.; Reverse transcriptase (RT) is an indispensable component of infectious retroviruses. We have developed an ultrasensitive RT test in which RNA of bacteriophage MS2 serves as the template for RT-mediated cDNA synthesis. A fragment of the cDNA is selectively amplified by polymerase chain reaction and the amplification pr
Induction of RNA-binding proteins in mammalian cells by DNA-damaging agents.: Proc Natl Acad Sci U S A. 1994 Feb 15;91(4):1554-8. Unique Identifier : AIDSLINE MED/94151368; Carrier F; Gatignol A; Hollander MC; Jeang KT; Fornace AJ Jr; Laboratory of Molecular Pharmacology, National Cancer Institute,; NIH, Bethesda, MD 20892.; A technique to detect RNA-binding proteins (RBP) involving hybridization of RNA probe to proteins transferred to a membrane was used to study RBP in different mammalian cells and in cells after genotoxic stress. With this approach, up to 13 proteins of different sizes were detected in crude nuclear extracts by using a
[HTLV-I and retinal antigen recognized by T cells]: Nippon Ganka Gakkai Zasshi. 1994 Feb;98(2):157-61. Unique Identifier : AIDSLINE MED/94152519; Fukushima A; Ueno H; Fujimoto S; Department of Ophthalmology, Kochi Medical School, Japan.; MT-2 immune but not naive murine (B10.BR) spleen cells responded not only to HTLV-I-infected cell lines but also to retinal antigens of various species by antigen-induced cell proliferation. The phenotype of the responding cells against HTLV-I-infected cell lines as well as retinal antigens was Thy-1.2+, CD4+ and CD8-
Incidence of CD4+ IL-2R alpha+ and CD4+ CD45RA+ T-cells in progressive multiple sclerosis and the influence of short-term (3 months) FK 506 therapy.: Ann N Y Acad Sci. 1993 Nov 30;696:245-9. Unique Identifier : AIDSLINE MED/94152922; Thomson AW; Woo J; Lemster B; Irish W; Huang LL; Carroll PB; Rilo HR; Abu-Elmagd K; Eidelman B; Department of Surgery, University of Pittsburgh Medical Center,; Pennsylvania 15213.
Inhibition of visna virus replication by 2',3'-dideoxynucleosides and acyclic nucleoside phosphonate analogs.: Antimicrob Agents Chemother. 1993 Dec;37(12):2540-4. Unique Identifier : AIDSLINE MED/94153023; Thormar H; Balzarini J; Holy A; Jindrich J; Rosenberg I; Debyser Z; Desmyter J; De Clercq E; Institute of Biology, University of Iceland, Reykjavik.; A series of acyclic nucleoside phosphonate (ANP) and 2 ,3 -dideoxynucleoside (ddN) derivatives were evaluated for their inhibitory effects on visna virus replication and maedi/visna virus-induced syncytium formation in s