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8th Annual Conference Of The British HIV Association [BHIVA]19 – 21 April 2002, University of York, York |
[AUTHOR(S):] C Hodgson1, L Hodgson2, S Murad1, J Herman1, C Taylor1, D Macallan2, P Easterbrook1
1 King's College Hospital and 2 St George's Hospital, London
BHIVA Conf 2002 Apr 19-21;8:P2
OBJECTIVE: To determine the prevalence of CVD risk factors in an ethnically diverse and antiretroviral-naïve population.
METHODS: Eligible patients were treatment-naïve HIV-1-positive individuals attending King's College and St George's Hospitals about to commence highly active antiretroviral therapy (HAART). A standardized questionnaire was used to collect data on demographic, lifestyle and CVD risk factors. An anthropometric and dietary assessment was also performed, with selected laboratory measures including cholesterol (CHL), high-density and low-density lipoprotein subfractions and triglycerides. A CVD risk factor score was generated using a British CVD risk model.
RESULTS: 64 patients have been enrolled to date; 60.9% were men, 42.2% were black African, 34.4% were white and 15.6% were black Caribbean. The median age at evaluation was 35.4 years, and the median CD4 count and viral load were 177 cells/μL and 78,522 copies/mL, respectively. The overall prevalence of CVD risk factors was: ever smoked (59.4%); current smoking (35.9%); heavy alcohol intake (>28 units for men and >21 units for women; 32.8%); family history of CVD risk factors (95.3%); body mass index ≥30 kg/m2 (6.3%) and waist circumference >88 cm (men) or >102 cm (women) (21.9%). Mean blood pressure and plasma lipids were within the normal range. There were significant differences in CVD risk factors according to sex and ethnicity. However, the overall 10-year risk of CHD over the next 10 years was <15%, based on the CVD risk model.
CONCLUSIONS: A high proportion of our patients have at least one modifiable CVD risk factor. This highlights the importance of identifying those who may benefit from lifestyle changes.
PRESENTING AUTHOR: C Hodgson
020419
P2
Copyright © 2002 - British HIV Association (BHIVA) Reproduction of this abstract (other than one copy for personal reference) must be cleared through the BHIVA Organising Secretariat 1 Mountview Court, 310 Friern Barnet Lane, London N20 0LD