11th Annual Conference Of The British HIV Association [BHIVA] 20–23 April 2005, Burlington Hotel·Dublin·Ireland

[AUTHOR(S):] JE Blackham¹, V Delpech¹, P Benn², BG Evans¹ on behalf of the NONOPEP project collaborative group.
¹HIV and Sexually Transmitted Infections Department, Health Protection Agency Centre for Infections, London, UK, ²Department of Genitourinary Medicine, Mortimer Market Centre, Camden PCT, London, UK

BHIVA Conf 2005 Apr 20-23;11:O16

AIM: To describe recent trends in PEP use for non-occupational exposures to HIV (NONOPEP), across 10 UK GUM/HIV clinics.

METHODS: Individuals attending 10 GUM/HIV clinics receiving NONOPEP between 11/2002 and 11/2004 were prospectively recruited. Demographic, behavioural and clinical data were collected at baseline, 4–6 weeks, 3 and 6 months.

RESULTS: 212 individuals have been recruited: 89% male, 74% men who have sex with men (MSM), 79% of white ethnicity, average age 32 years (range 18-64). 91% received PEP following high-risk sexual exposures, 22% with regular partners. 42/156 (27%) MSM and 13/22 (60%) women receiving PEP reported unprotected intercourse (anal/vaginal respectively) with an HIV positive partner. All cases received PEP in accordance with BASHH guidelines. Follow-up rates to date are low: 4–6 weeks (57%); 3 months (35%); 6 months (28%). Of the 128 followed-up: 86% completed the 4-week PEP course, 75% adhered fully and 56% experienced mild-moderate side effects. During the study period numbers prescribed NONOPEP increased by 98% (range 60%–1400%); with the greatest increase occurring in London (172%) in the later part of 2004.

CONCLUSIONS: The demand for NONOPEP is increasing, particularly in London and among MSM. The reasons for low follow-up rates are unclear and need to be addressed.

PRESENTING AUTHOR: JE Blackham

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2005-04-20
O16

Copyright © 2005 - British HIV Association (BHIVA) Reproduction of this abstract (other than one copy for personal reference) must be cleared through the BHIVA Organising Secretariat 1 Mountview Court, 310 Friern Barnet Lane, London N20 0LD