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11th Annual Conference Of The British HIV Association [BHIVA]20–23 April 2005, Burlington Hotel·Dublin·Ireland |
[AUTHOR(S):] P Collini1, M Adjei1, K Torpey2, R Amenyah2, D Chadwick3, G Bedu-Addo1
1Komfo Anokye Teaching Hospital HIV/AIDS Clinic, Kumasi, Ghana, 2Family Health International, Accra, Ghana, 3James Cook University Hospital, Middlesbrough, UK
BHIVA Conf 2005 Apr 20-23;11:O9
OBJECTIVE: To review presentation of 200 patients and their response after 6 months of antiretroviral therapy (ART) attending the new ARV clinic in Komfo Anokye Teaching Hospital.
METHODS: Prospective observational study of first 200 ART patients.
RESULTS: Family Health International's START program in partnership with the National AIDS Control Program/Ministry of Health and DFID have scaled up the delivery of ART in Ghana. In its first year this clinic enrolled 1738 patients and started over 600 on treatment. All received 2NRTI+1NNRTI except one (2NRTI+1PI). 188 were ART naïve. 128 had a regime containing AZT (M=58), 21 later switched to d4T because of anaemia. 71(M=25) started on d4T. Efavirenz was given to 101(M=71), nevirapine to 95(M=11). No cases of nevirapine induced hepatitis were recorded. 8 were switched from nevirapine to efavirenz on developing tuberculosis. Mean (median) CD4 count increased by 166(158) from 125(123) cells/mm3 and weight increased from 50.7(50) to 58.0(58) Kg. 4 deaths were recorded. 15 patients defaulted follow up by more than 3 months. More than 80% of patients reported greater than 95% adherence on every follow up visit over the period. Further data on this cohort will be presented.
CONCLUSIONS: Effective and safe ART is achievable when scaling up.
PRESENTING AUTHOR: P Collini
2005-04-20
O9
Copyright © 2005 - British HIV Association (BHIVA) Reproduction of this abstract (other than one copy for personal reference) must be cleared through the BHIVA Organising Secretariat 1 Mountview Court, 310 Friern Barnet Lane, London N20 0LD