1st EACS RESISTANCE & PHARMACOLOGY WORKSHOP
October 25 - 29, 2003 Warsaw • Poland
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9TH EUROPEAN AIDS CONFERENCE (EACS) 1st EACS RESISTANCE & PHARMACOLOGY WORKSHOP October 25 - 29, 2003 Warsaw • Poland |
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18.4 Morbidity/Mortality in the Era of HAART F9/7 - CHANGES IN HOSPITAL ADMISSIONS ACROSS EUROPE IN 1995-2002 |
Objective: To describe changes in the proportions of patients admitted to hospital and duration of admission during the month of March 1995-2002 in 9803 patients from the EuroSIDA cohort and factors related to admission.
Methods: Linear regression was used to describe changes in the proportion of patients admitted and the duration of admission. Logistic regression was used to determine factors related to admission in 1995, 1998 and 2001.
Results: The proportion of patients admitted declined from 7.4% in 1995 to 2.6% in 2002; the estimated reduction was 0.77%/year (95%-CI 0.45#1.09%, p = 0.0032). The median duration of admission declined from 12 days in 1995 (interquartile range, IQR 5 - 19) to 6 days during 2002 (IQR 3 - 11), a decline of 1.00 days/year (95%-CI 0.48 # 1.52, p = 0.0090). Patients with a lower CD4 count, and with a recent AIDS diagnosis were more likely to be admitted during March 1995, 1998 or 2001. In March 1998 and 2001, patients who made a change to their treatment-regimen were more likely to be admitted (odds ratio (OR) 2.44; 95%-CI 1.68 # 3.53, p < 0.0001 and OR 3.08; 95% CI 1.31 # 7.18, p = 0.010 respectively). In 2001, patients coinfected with Hepatitis C had an increased risk of admission (OR 1.78; 95% CI 1.11 # 2.86, p = 0.018).
Conclusions: There has been a considerable decline in both the proportion of patients admitted to hospital and the median duration of the stay.
Presenting Author: Professor Antonella d'Arminio-Monforte, Institute of Infectious and tropical Diseases, University of Milan, L Sacco Hospital, via GB Grassi 74, 20157, Milan, Italy, Phone: +39 02 3560010
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