1st International AIDS Conference Atlanta, Georgia, U.S.A. - April 14-17, 1985

Int Conf AIDS 1985 Apr 14-17; 1:22 (abstract no. S2C)

James Oleske, M Zabala, A Minneror, T Denny, R Bobila, V Joshi
UMD-New Jersey Medical School; Children's Hospital of New Jersey; St. Michael's Med. Ctr, Newark; and St. Joseph's Medical Center, Paterson, New Jersey.

Our first group of pediatric AIDS patients was initially reported in March 1983. These children were born in high-risk households; either the offspring of IV drug addicted mothers or their mother was a sexual partner of an IV drug user. Since 1979 a total of 34 infants or children belonging to high-risk groups have been evaluated and treated at UMDNJ and affiliated hospitals. Twenty meet the present diagnostic criteria for AIDS while 14 belong to the less defined pediatric AIDS related complex (ARC). 12 of our 20 AIDS cases have died while only one of our ARC cases. These children all died of opportunistic infections, none had Kaposi's Sarcoma. Of the 34 patients 20 were born to drug using mothers; 3 to sexaul partners of IV drug users; 4 are pediatric hemophiliacs, 2 of Haitian parentage and 4 related to neonatal blood transfusions. Two mothers and two fathers have been subsequently diagnosed with AIDS. Nine of our 34 patients required foster care. The mean age of onset for the total group was 7 mos; for AIDS cases 2 mos, and for ARC 17 mos. There were 5 infants with symptoms at birth. Fourteen household contacts exclusive of the parents (8 sibs and 6 foster mothers) have remained clinically normal over a 30 month observation period. Pediatric AIDS appears to be vertically transmitted with no evidence of horizontal household transmission.

850414
S2C

Copyright © 1985 - International AIDS Society (IAS). Reproduction of this abstract (other than one copy for personal reference) must be cleared through the IAS.