1st International AIDS Conference Atlanta, Georgia, U.S.A. - April 14-17, 1985

Int Conf AIDS. 1985 Apr 14-17;1:24 (abstract no. S5B)

William W Darrow, P O'Malley, HW Jaffe, JE Getchell, RH Byers, DF Echenberg
CDC, Atlanta, Georgia, and Department of Public Health, San Francisco, California.

In a sample of homosexual men, randomly selected from a cohort formed in 1978-1980 to study hepatitis B virus (HBV) infections, we tested stored sera collected when men entered the cohort and sera collected in 1983-1984 for antibodies to HTLV-III/LAV by an enzyme-linked immunosorbent assay. Of 362 men who were initially seronegative, 241 (66.6%) had developed antibodies to HTLV-III/LAV by 1983-1984. Risk factors for HTLV-III/LAV seroconversion were assessed with data collected from 232 men in 1978-1980 and follow-up information collected from 362 men in 1983-1984. Variables predictive of HTLV-III/LAV seroconversion in prospective analyses included younger age, serologic marker of HBV infection, rectal douching, toothbrush sharing, and frequent receptive anal intercourse leading to ejaculation with many partners. In retrospective analyses, major variables associated with HTLV-III/LAV seroconversion were receptive anal intercourse, serologic marker of HBV infection, younger age, many partners, rectal bleeding, and syphilis after entry into the cohort. HTLV-III/LAV infections are now common among cohort members and are related to specific sexual practices with multiple partners.

850414
S5B

Copyright © 1985 - International AIDS Society (IAS). Reproduction of this abstract (other than one copy for personal reference) must be cleared through the IAS.