!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd"> AEGiS-1IAC: ENVELOPE PROPERTIES OF THE AIDS RETROVIRUS

1st International AIDS Conference


Atlanta, Georgia, U.S.A. - April 14-17, 1985

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ENVELOPE PROPERTIES OF THE AIDS RETROVIRUS

Int Conf AIDS. 1985 Apr 14-17;1:25 (abstract no. S6D)

Angus Dalgleish, P Clapham, R Cheingsong-Popov, M Exley, RA Weiss
Institute of Cancer Research, Royal Cancer Hospital, London.

We have used biological assays of the AIDS retrovirus to investigate the interaction of the envelope glycoprotein with the host imune system. Our findings demonstrate that (1) the T4 antigen is an essential cell surface component of the virus receptor, (2) infected individuals whether healthy or immunocompromised are deficient in producing specific virus-neutralizing antibodies and (3) different isolates of the retrovirus appear to have different envelope properties.

850414
S6D

Copyright © 1985 - International AIDS Society (IAS). Reproduction of this abstract (other than one copy for personal reference) must be cleared through the IAS.