AEGiS-1IAC: BACTEREMIA AND FUNGEMIAS IN PATIENTS WITH AIDS.

1st International AIDS Conference

Atlanta, Georgia, U.S.A. - April 14-17, 1985

BACTEREMIA AND FUNGEMIAS IN PATIENTS WITH AIDS

Int Conf AIDS. 1985 Apr 14-17;1:26 Abstract No. S7C

Estella Whimbey, T Kiehn, P Brannon, A Blevins, J Gold, D Armstrong
Memorial Sloan-Kettering Cancer Center, New York City, New York.

Forty episodes of bacteremia and fungemia have occurred in 34 of 295 patients with AIDS cared for at MSKCC. There were 4 types of infections. I. Infections associated with a T-cell immunodeficiency [Salmonella (6), Cryptococcus (5), Listeria (2)]. II. Nosocomial infections [C. albicans (4), S. epid. (4), non-Salmonella gram neg. rods (2), S. aureus (2), and mixed S. aureus and group-G strep. (1)]. III. Infections associated with neutropenia [Pseudomonas (1)]. IV. Other infections, all of which were diagnosed within 24 h of admission to the hospital [S. aureus (8), S. pneum.(1), group-B strep. (1), S. faecalis (1), S. epid. (1), and C. perfringens (1)]. The 8 community acquired S. aureus bacteremias were due to soft tissue infections (5) or pneumonias (3); none were associated with IV drug abuse. All S. aureus pneumonias were associated with pulmonary KS and PCP. We conclude that some infections present on admission to the hospital were due to organisms which were not associated with T-cell defects, as well as to organisms which can be anticipated in patients with AIDS. This must be considered in the evaluation of the febrile patient with AIDS when presumptive therapy is planned. In addition, patients with PCP may also be infected with bacteria, e.g. S. aureus, which require treatment.

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S7C