5th International AIDS Conference


Montreal, Quebec, Canada — Jun 4-9, 1989

Cite as: Int Conf AIDS. 1989 Jun 4-9, 1989;5:Abstract No. xx

Problems in the interface between the medical treating system and the patient/family system.
Int Conf AIDS 1989 Jun 4-9; 5:931 (abstract no. 771)
Patten J; The Ackerman Institute for Family Therapy, New York, New York, USA
Many medical management problems occur in AIDS patients because of poor relationships between patient/family and the medical system (doctors, social workers, nurses, administrators, etc.). The Ackerman AIDS Project, by using psychotherapeutic and educational techniques with many individuals, couples, and families and m


HIV-seroprevalence among patients of a West-German inner-city general practice.
Int Conf AIDS 1989 Jun 4-9; 5:161 (abstract no. A.501)
Zeschel A, Meyer-Glauner W; Arzt f.Allegemeinmed., Hannover, FRG
OBJECTIVES: 1.) To screen selected subpopulations among patients of a general practice as an economical alternative to untargeted mass-screening. 2.) Early detection of HIV-infection among high- and low-risk groups. 3.) To counsel and treat these otherwise unrecognized HIV-carriers as a contribution to the containment


HIV infection related to the use of contaminated material in commercial plasma donors.
Int Conf AIDS 1989 Jun 4-9; 5:161 (abstract no. A.502)
Clotet B, Carles J, Tural C, Sirera G, Dominguez M, Tor J, Foz M; Infectious Diseases Unit. Hospital de Badalona "Germans Trias i Pujol", Badalona, Barcelona, Catalonia, Spain
To identify the risk factors for AIDS reported by 33 HIV seropositive paid blood/plasma donors. MATERIAL: Patients who donated blood in private centers in a retributed manner and were found HIV seropositive. In all cases HIV antibodies were evaluated by ELISA and Western Blot methods. In 11 out of 3


Risk of HIV transmission to health care workers and comparison with viral hepatitides.
Int Conf AIDS 1989 Jun 4-9; 5:161 (abstract no. A.503)
Rastrelli M, Ferrazzi D, Vigo B, Giannelli F; Niguarda Ca Granda Hospital, Milan, Italy
To assess the risk of nosocomial transmission of HIV in comparison with viral hepatitides and record the effects of adopting further protective and educational means. During the period June 1986-December 1988, all health care workers accidentally exposed to HIV in hospital had entered the study and


Monitoring prevalence of HIV infection and epidemiological patterns through laboratory data.
Int Conf AIDS 1989 Jun 4-9; 5:161 (abstract no. A.504)
Casabona J, Bosch A, Tor J, Segura A; AIDS Program. Generalitat de Catalunya. Barcelona, Spain
OBJECTIVES: 1.- To estimate the prevalence of HIV infection among people who request the test in Catalonia. 2.- To describe the demographic and behavioral characteristics of this population. All laboratories performing HIV test within the Public Health System are used. The total number of test and their result


Prevalence of infection with human immunodeficiency virus among drug users in Puerto Rico.
Int Conf AIDS 1989 Jun 4-9; 5:161 (abstract no. A.505)
Gorbea HF, Garcia ME; University of Puerto Rico School of Medicine, San Juan, Puerto Rico, USA
To study the prevalence of HIV infection among drug users (DU) in a drug treatment program in Puerto Rico (PR). DU voluntarily agreed to participate in the study. Information concerning drug use, sexual and medical history was obtained. A screening test (EIA) and supplemental test (Western blot or I


International networking of HIV public health services.
Int Conf AIDS 1989 Jun 4-9; 5:161 (abstract no. A.506)
Daniell FD, Skelly R, Sanderson R, Novak D, Cunnion S; Navy Environmental and Preventive Medicine Unit, Naples, Italy
To expand public health capabilities against the HIV epidemic, a networking of existing U.S. Navy preventive medicine programs and approaches was initiated during 1988, utilizing an STD model. International networking involves utilization of services provided at a medical center caring for HIV-infec


Men meet women: differential risk-reducing needs and tactics in encounters between people drawn from the general population pool.
Int Conf AIDS 1989 Jun 4-9; 5:162 (abstract no. A.507)
Shtarkshall RA, Awerbuch T; The Hebrew University & Hadassah Faculty of Medicine, Jerusalem, Israel
Utilizing equations which were developed for probabilities of HIV infection through sexual intercourse, we demonstrate the asymmetry of the probabilistic risks for a man and and a woman engaging in sexual intercourse in a Western society. Two factors determine this asymmetry: 1. The prevalence of AIDS and HIV seroposit


"Groups at risk" and "risk behaviors": the need to utilize both concepts in describing target populations for educational interventions and defining their objectives.
Int Conf AIDS 1989 Jun 4-9; 5:162 (abstract no. A.508)
Shtarkshall RA; The Hebrew University & Hadassah Faculty of Medicine, Jerusalem, Israel
The central claim of the paper is that the two concepts, groups at risk and risk behavior are neither synonymous nor interchangeable, and that in order to describe target groups for educational or other interventions, both terms are needed. Risk behavior or its prevalence is only one component of the definition of a g


Surveillance of HIV-2 infections by ELISA using HIV-1 and HIV-2 specific synthetic peptides.
Int Conf AIDS 1989 Jun 4-9; 5:162 (abstract no. A.509)
Leinikki P, Hakulinen J, Kantanen ML, Brummer-Korvenkontio H; National Public Health Institute, Helsinki, Finland
To screen for HIV-2 cases in Finland and to evaluate a new test employing HIV-1 and HIV-2 specific synthetic peptides as antigens. Serum samples sent for routine HIV-testing from healthy individuals and HIV risk groups were tested by an ELISA with either a combination of, or individual HIV-1 or HIV-


HTLV seroprevalence in a group of HIV positive Italian subjects (in majority intravenous drug abusers) - proemial data.
Int Conf AIDS 1989 Jun 4-9; 5:162 (abstract no. A.510)
Lopalco L, Ciccomascolo F, Lanza P, Berretta A, Bini A, Sabbatani S; Italy
AIMS: We detected the presence of specific HTLVI antibodies in HIV1 positive subjects to evaluate (1) the percentage of double infection (2) if the subjects with double infection presented an evolutive pattern. The presence of specific HTLVI antibodies was tested by Elisa method in 240 HIV1 positive subjects (


Incidence of HBV markers and HIV antibodies in blood donors in Luanda and Dundo, People's Republic of Angola.
Int Conf AIDS 1989 Jun 4-9; 5:162 (abstract no. A.511)
Lourenco MH, Cohen T, Octavio F, Santos-Ferreira MO, Matos-Almeida MJ, Azevedo Pereira JM; Lab. Virology, Fac. Pharmacy, Univ. Lisbon, Portugal
To determine the prevalence of HIV 1 and HIV 2 infection and hepatitis B markers among a cohort of blood donors in two regions of Angola . The incidence of HBV markers and HIV antibodies was evaluated in 124 blood donors living in Luanda (74) and Dundo (50). Serological tests for detection of HIV an


Analysis of a screening program for HIV1 and HIV2 infection in women of reproductive age.
Int Conf AIDS 1989 Jun 4-9; 5:162 (abstract no. A.512)
Victorino R, Teles LC, Ferreira MO, Guerreiro D, Lourenco MH; Faculty of Medicine of Lisbon, Av. Prof. Egas Moniz - 1600 Lisbon - Portugal
OBJECTIVES: 1 - To study the prevalence of antibodies to HIV1 and HIV2 in a population of women attending a Family Planning Clinic (FPC) and a antenatal clinic (AC) serving a urban population of 30.000 people where about 10% are of African origin. 2 - Devise a protocol of a study which would maintain characteristics of


Stochastic models illustrate vividly the connection between behavior and risks for HIV infection.
Int Conf AIDS 1989 Jun 4-9; 5:163 (abstract no. A.513)
Gonzalez JJ, Myrtveit M, Vavik L; ASA, Arendal, Norway
To use the power of modern Personal Computers to display graphically the connection between behavior and risk for HIV infection. A stochastical simulation model takes into account behavior parameters in a hypothetical risk environment. The correlation between behavior patterns and risk for HIV infec


HIV screening efforts in a low-risk population.
Int Conf AIDS 1989 Jun 4-9; 5:163 (abstract no. A.514)
Magruder CD, Sanchez JL, Huffman P, Lewis VM, Quattromani FL; Womack Army Community Hospital, Ft Bragg, NC, USA
To determine the prevalence of HIV antibody seropositivity in a low-risk population. The U.S. Army requires HIV testing at least biennially for individuals on active duty. Blood donors are also routinely screened for HIV infection. During the past year, inpatients and some outpatients have received


Is sexual promiscuity a risk factor for HHV6 in East Africa?
Int Conf AIDS 1989 Jun 4-9; 5:163 (abstract no. A.515)
Fox E, Constantine N, Abbatte EA; U.S. Naval Medical Research Unit No. 3, Cairo, Egypt
To investigate if the B-cell lymphotropic virus HHV6 shares the sexual transmission route of HIV in East Africa. 200 sera belonging to 4 groups of individuals from the East African city of Djibouti were tested for antibodies against HHV6. Study groups comprised sexually promiscuous individuals at hi


A prospective study of HIV infection in former drug users: a 4-year study of 114 patients.
Int Conf AIDS 1989 Jun 4-9; 5:163 (abstract no. A.516)
Gringeri A, Rumi MG, Colombo M, Zanetti AR, Romeo R, Mannucci PM; University of Milan, Milan, Italy
To assess whether or not stopping drugs has any beneficial effect on the course of HIV infection, inactive drug users living in the community of San Patrignano ( Italy ) were prospectively followed. These patients voluntarily enrolled into a rehabilitation program based on agricultural, handicraft a


Accidental exposures to HIV-positive blood among health-care workers in 2 Swedish hospitals.
Int Conf AIDS 1989 Jun 4-9; 5:163 (abstract no. A.518)
Jorbeck H, Marland M, Steinkeller E; Danderyd Hospital, Danderyd, Sweden
OBJECTIVES: To document circumstances, frequency and outcome of accidental exposures to HIV-positive blood and bloody body fluids among health-care workers. This prospective study was started in January 1, 1985. It includes health-care workers in 2 Swedish hospitals giving medical care for HIV-infected persons


National study of HIV seroprevalence in Native Americans.
Int Conf AIDS 1989 Jun 4-9; 5:164 (abstract no. A.519)
Conway GA, Hooper EY, Helgerson SD, Petersen LR, Leach R, Johannes P; Centers for Disease Control, Atlanta, Georgia
To assess existing levels and future trends of HIV infection among American Indians and Alaska Natives in the United States . Following approval from tribal authorities, blinded seroprevalence testing will be conducted on sera obtained for syphilis screening from prenatal patients, patients undergoi


Detection of HIV antibodies in dental school at the Buenos Aires University.
Int Conf AIDS 1989 Jun 4-9; 5:164 (abstract no. A.520)
Crespo D, Sabelli C, Trica A, Brizuela L, Ramella M, Muchinik G; Catedra de Microbiologia, Fac. de Odontologia, U.B.A., Argentina
The aim of this work was to determine the seroprevalence of HIV infection in dental professionals as they represent an important group to study for occupational risk of HIV infection. A total of 617 subjects were included in this study. 400 were first year students at the School of Dentistry, 112 pr


Seroprevalence of HIV antibody in a citywide sample of emergency room patients.
Int Conf AIDS 1989 Jun 4-9; 5:164 (abstract no. A.521)
Modesitt S, Jui J, Stevens P, Hulman S, Shriver J, Fleming D; Oregon Health Sciences University, Portland, Oregon, USA
OBJECTIVES: To determine prevalence of HIV antibody in a citywide population of patients seeking emergency room (ER) care. Seven hospital-based emergency rooms providing 90% of Portland s emergency services collaborated to simultaneously measure HIV seroprevalence in their combined patient population. During t


Sexual mixing models with like-with-like preference.
Int Conf AIDS 1989 Jun 4-9; 5:164 (abstract no. A.522)
Blythe S, Castillo-Chavez C; Strathclyde University, Glasgow, Scotland
To develop an alternative to proportionate mixing in sexually transmitted disease models. Starting from the three fundamental constraints on a mixing function (it must be positive, normalized, and conserve the number of partnerships), a new mixing model can be constructed by finding an appropriate t


Acceptance of HIV-antibody screening and prevalence of antibodies against HIV at a STD clinic.
Int Conf AIDS 1989 Jun 4-9; 5:164 (abstract no. A.523)
Kvinesdal BB, Worm AM; Statens Seruminstitut, Copenhagen, Denmark
During periods of three weeks repeated every third month from October 1987 to November 1988, all persons attending a STD clinic in Copenhagen for examination were offered a blood test for HIV-antibodies. The test could be performed anonymously or not. Data concerning sexual orientation, prostitution, drug abuse and sex


The influence of changes in sexual behaviour on the transmission dynamics of HIV-1 in the UK.
Int Conf AIDS 1989 Jun 4-9; 5:164 (abstract no. A.524)
Gupta S, Blythe S, Anderson RM; Imperial College, London, UK
To assess the consequences of changes in sexual behaviour on the transmission dynamics of HIV-1 with reference to the male homosexual community in the United Kingdom . The distribution of sexual activity (rate of acquiring new partners) and transmission probabilities (mirroring the adoption of safe


HIV seropositivity in IVDU Vietnam combat veterans.
Int Conf AIDS 1989 Jun 4-9; 5:165 (abstract no. A.525)
Kocurek K, Bacchetti P, Gorter R, Meakin R, Moss AR; University of California, San Francisco, California, USA
To determine the rate of HIV infection in heterosexual military veterans who use intravenous drugs and are seen in methadone treatment facilities. Heterosexual IVDUs attending methadone treatment facilities in San Francisco between February and December 1988 were recruited, screened for military ser


Completeness and accuracy of risk factor information in a general population surveillance of HIV infection.
Int Conf AIDS 1989 Jun 4-9; 5:165 (abstract no. A.526)
Perucci CA, Arca M, Carboni A, Orchi N, Spadea T; Regional Epidemiology Unit, Rome, Italy
To detect and quantify the biases due to missing information about risk factor in data from a general population surveillance of HIV. Anonymous notification of every confirmed anti-HIV positivity, including available information on risk factor, has been collected by the Latium R.E.U. from local labo


Temporal trends of HIV prevalence in blood donors and use of blood banks as testing sites in Latium (Italy).
Int Conf AIDS 1989 Jun 4-9; 5:165 (abstract no. A.527)
Perucci CA, Arca M, Abeni D, Chierchini P; Regional Epidemiologic Unit, Rome, Italy
To evaluate changes over time in number and characteristics of blood donors and their effect on observed prevalence trends of HIV infection and to evaluate the effectiveness of screening programmes. In the Latium region (about 5,000,000 inhab.) screening of every donated blood unit has been mandator


HIV seroprevalence in Hispanic amnesty applicants at a sexually transmitted diseases (STD) clinic, Los Angeles, California, 1988.
Int Conf AIDS 1989 Jun 4-9; 5:165 (abstract no. A.528)
Nahlen B, Kerndt P, Ford W, Johnson M, Waterman S; Centers for Disease Control, GA, USA
To estimate and compare HIV antibody (Ab) seroprevalence in undocumented Hispanics seeking legal amnesty with that of other Hispanics attending the same STD clinic. Amnesty applicants must prove residence in the USA since Jan. 1, 1982, and undergo HIVAb testing. Repeat ELISA positives are confirmed


Seroprevalence of HIV antibody in IV drug users and other patients in a Connecticut hospital.
Int Conf AIDS 1989 Jun 4-9; 5:165 (abstract no. A.529)
Lyons RW, Krisiunas E, Madden G, Rubinstien E, Smith C, Dauphinais R; St. Francis Hospital and Medical Center, Hartford, Connecticut, USA
To examine the demographics of HIV antibody seroprevalence at a 592 bed community teaching hospital in the northeastern United States in 1988. Sex, race, age, and risk-group information was obtained by the laboratory from the ordering physician on all HIV antibody tests done. Patient identifiers wer


The epidemiology of AIDS in Maryland, 1981 - 1987.
Int Conf AIDS 1989 Jun 4-9; 5:165 (abstract no. A.530)
Horman J, Hamidi C; AIDS Administration, MD Department of Health, Baltimore, MD, USA
Describe the epidemiology of AIDS in Maryland for the years 1981 through 1987. Case reports completed as part of the Maryland AIDS Reporting System were analyzed. A total of 1,017 nonincarcerated adult AIDS cases was reported during this 7 year period. The greatest proportion of cases occur


[3 year surveillance of T4 lymphocytes and B2 microglobulin in a cohort of 166 subjects infected with HIV]
Int Conf AIDS 1989 Jun 4-9; 5:166 (abstract no. A.531)
Brugnetti A, Negre M, Pesce A, Fuzibet JG, Quaranta JF, Dujardin P, Cassuto JP; C.H.R.U. de Nice, France
Screening for HIV infection among IV drug users in the prisons of Brussels.
Int Conf AIDS 1989 Jun 4-9; 5:166 (abstract no. A.532)
Donot A, Verhoeven-Lespagnard L, Lumer G; CMC Prison de St Gilles, Brussels, Belgium
To monitor the epidemic of HIV infection among IV drug users (IVDU) in the Brussels area through screening of the inmates of Brussels prisons and, at the same time, monitor the effect of information on the behavior of the IVDU population. Since May 1985, an information campaign on AIDS was launched


Federal support of state and local HIV prevention programs in the United States.
Int Conf AIDS 1989 Jun 4-9; 5:166 (abstract no. A.533)
Bowen GS, West GR, Kirby J, Cates W, Hinman AR; Centers for Disease Control (CDC), Atlanta, GA, USA
To provide financial and technical assistance to State and local health departments for the prevention of HIV transmission in the U.S. CDC is the lead federal agency in the U.S. Government for development, implementation, and evaluation of national efforts to prevent transmission of HIV and to contr


HTLV-I/II infection in high-risk groups in Spain.
Int Conf AIDS 1989 Jun 4-9; 5:166 (abstract no. A.534)
Genesca J, Viladomiu L, Talavera JC, Shih J, Alter H, Esteban JI; Department of Transfusion Medicine, NIH, Bethesda, MD, USA
To determine the prevalence of HTLV-I/II infection in Spanish populations at high-risk for HIV infection. Serum samples were obtained from 150 subjects (1987-88) distributed in 110 drug users, 15 heterosexual contacts, 22 homosexuals and 3 post-transfusional HIV infections; 93% of them were anti-HIV


An analysis of AIDS in British Columbia.
Int Conf AIDS 1989 Jun 4-9; 5:166 (abstract no. A.535)
Rekart ML; STD Control, Ministry of Health, Vancouver, British Columbia, Canada
To describe reported cases of AIDS in B.C. through 1988 and to analyze trends. The 464 AIDS cases reported in B.C. to the end of 1988 are divided into two halves: the initial 232 cases (Group I) and the latest 232 cases (Group II). The characteristics of these two groups are described and compared.


Evolution towards AIDS in a group of Italian intravenous drug abusers (IDA) with PGL.
Int Conf AIDS 1989 Jun 4-9; 5:166 (abstract no. A.536)
Luzzati R, Giraldi D, Malena M, Mazzi R, Ciaffoni S, Roata C; Institute of Infectious Diseases, Verona, Italy
To evaluate the 3-year progression rate to AIDS in a group of IDA with PGL in Verona ( Italy ). One hundred and thirtytwo IDA (mean age 27 +/- 6 years) with PGL were enrolled in a prospective study between July 1984 and June 1986. Except for PGL, all patients were symptomless and had CD4+ lymphocyte


Impact of revised case definition on AIDS surveillance in Europe.
Int Conf AIDS 1989 Jun 4-9; 5:167 (abstract no. A.537)
Ancelle-Park R, Couturier E, Brunet JB; WHO Collaborating Centre on AIDS, Paris, France
To determine the modalities of application and impact of the revised CDC/WHO AIDS case definition on surveillance in Europe. A survey was carried out among the 32 countries of the WHO European region investigating modalities of surveillance of AIDS and application of revised cases definition. RESULT


The incidence of glove puncture during Caesarian section and various potential solutions.
Int Conf AIDS 1989 Jun 4-9; 5:167 (abstract no. A.538)
Smith JR, Grant JM; Department of Obstetrics, St Mary's Hospital, London, United Kingdom
A study was performed to ascertain the incidence of glove puncture at lower uterine segment Caesarian section. The increasing incidence of Hepatitis B and HIV infection in women makes this of increasing importance to surgeons. The following results were obtained: TABULAR DATA, SEE ABSTRACT VOLUME. This trial shows the


[Modifications and geographical variations in transmission groups of HIV infections in France]
Int Conf AIDS 1989 Jun 4-9; 5:167 (abstract no. A.539)
Jestin C; Ligue Francaise pour la Prevention des Maladies Infectieuses, France
HIV seropositive men infected with multiple CMV strains: a longitudinal study of the relationship to T-cell subsets.
Int Conf AIDS 1989 Jun 4-9; 5:167 (abstract no. A.540)
Leach C, Detels R, Visscher B, Giorgi J, Cherry J; UCLA Sch. of Medicine, Los Angeles, CA, USA
To investigate the relationship between serial infection with multiple CMV strains and T-cell subsets. We identified 56 asymptomatic HIV-1 seropositive homosexual men participating in a study of HIV-1 infection who excreted CMV from semen at two visits 5 to 9 months apart. CMV DNA was isolated from


Safer sex behavior reinforcement in public parks.
Int Conf AIDS 1989 Jun 4-9; 5:167 (abstract no. A.541)
Lerro M, Freeman A, Valentine J, Haley CE; Dallas County Health Department, Dallas, Texas, USA
Reinforce safer sex behaviors among sexually active gay men. Health department staff learned of the high frequency of contact for sexual purposes among gay and bisexual men, particularly at one public park in a gay-identified neighborhood in Dallas. The health department employees prepared packets f


Prevention of perinatal transmission of HIV.
Int Conf AIDS 1989 Jun 4-9; 5:167 (abstract no. A.542)
Berman S; Centers for Disease Control, Atlanta, GA USA
To report progress to date by projects to prevent perinatal HIV transmission. Nine demonstration projects evaluate and facilitate the use of contraception and encourage risk reduction among women HIV-infected or at highest risk for infection. The projects, funded for $4.6 million per yr, ar


[HIV, syphilis and drug abuse]
Int Conf AIDS 1989 Jun 4-9; 5:168 (abstract no. A.543)
Espinoza P, Loubeyre JL, Benamouzig R, Bouchard I; Etablissement d'Hospitalisation Public National de Fresnes, France
Detection of occlusion vs leak in condom rheological test.
Int Conf AIDS 1989 Jun 4-9; 5:168 (abstract no. A.544)
Torres J, Anabitarte H, Usieto R, Noguera E; Comite Anti-SIDA, Barcelona, Spain
The condom is recommended and used as an efficient barrier against HIV and others. In practice, the film of a condom may present irregularities or leaks. This has been resolved efficiently with rigorous sampling plans for leak-detection tests, realized in all standards by conductometric or electronical test


Early course of HIV infection in 40 seroconverters.
Int Conf AIDS 1989 Jun 4-9; 5:168 (abstract no. A.545)
Alessi E, Muratori S, Zerboni R, Cusini M, Carminati G, Mansi M; 1st Clinic of Dermatology, University of Milan, Milan, Italy
To study the natural history of HIV infection. Forty homosexuals, who became seropositive from December 1985 to January 1988, were followed from 11 to 36 months (mean 23 months). The mean time between the last negative and first positive tests was considered to be the time of infection. Clinical, im


Natural history of HIV infection in females seen at the Medical College of Virginia (MCV).
Int Conf AIDS 1989 Jun 4-9; 5:168 (abstract no. A.546)
Berry A, Fortner C, Settle J, Kaplowitz L; Medical College of Virginia, Richmond, VA, USA
To describe the natural history of HIV infection in females seen at MCV. This study retrospectively compares the clinical course of 66 HIV infected women with 412 HIV infected men followed at MCV from 4/86 to 1/89. Females comprised 14% of the HIV infected population seen at MCV; 50 (77%) w


[Epidemiological profile of infections due to human immunodeficiency virus (HIV) in Estrie]
Int Conf AIDS 1989 Jun 4-9; 5:168 (abstract no. A.547)
Duperval R, Boivin D, Marcoux JA, Lepine M, Saad WP; Universite de Sherbrooke, Sherbrooke, Quebec, Canada
Long term follow-up of homosexual men with persistent lymphadenopathy: attack rate for AIDS.
Int Conf AIDS 1989 Jun 4-9; 5:168 (abstract no. A.548)
Sepkowitz K, Gold JW, Campbell SW, Armstrong D; Memorial Sloan-Kettering Cancer Center (MSKCC), New York, NY, USA
To determine the attack rate for AIDS in a cohort of 93 homosexual men identified with lymphadenopathy between 1981-1983. Cases of AIDS occurring in a previously described cohort (Medicine 1985; 64: 203-213.) followed at MSKCC were documented. Patients lost to follow-up (LF) were traced. The attack


Lack of association between frequency of blood donation and seropositivity for HIV and other infections; an unexpected finding in Rio de Janeiro - Brazil.
Int Conf AIDS 1989 Jun 4-9; 5:169 (abstract no. A.549)
Ramos Filho CF, Perez MA, Chain R, Martins FS, Jesus VC, Martins CN; Federal University of Rio de Janeiro, Rio de Janeiro (RJ) Brazil
Due to the importance of blood transmission in the diffusion of infectious disease in RJ we have performed this study in order to better understand blood transmitted disease and frequency of blood donation. 2,858 (non-paid) blood donors (18 to 60 years old) from the hemotherapeutic center of our hos


Seroepidemiology of human immunodeficiency virus type-I and viral hepatitis infection in New York City intravenous drug users (IVDUs).
Int Conf AIDS 1989 Jun 4-9; 5:169 (abstract no. A.550)
Brown LS, Kreek MJ, Trepo C, Chu A, Ajuluchukwu D, Phillips R; Addiction Research and Treatment Corporation, Brooklyn, NY, USA
To examine the behaviors associated with HIV-1 and viral hepatitis infection in IVDUs enrolled in drug treatment. As a part of a larger HIV seroprevalence study in which a standardized questionnaire was administered, 50 subjects were recruited from patients enrolled in drug treatment in NYC in 1987.


Trends in AIDS incidence based on active surveillance in 12 medical school affiliated hospitals.
Int Conf AIDS 1989 Jun 4-9; 5:169 (abstract no. A.551)
Lavenhar MA, Schneider DJ; UMDNJ-New Jersey Medical School, Newark, New Jersey, USA
To demonstrate how trends in AIDS incidence can be assessed utilizing data obtained through active surveillance in 12 hospitals affiliated with the New Jersey Medical School. Analyses will focus on descriptive methods for presenting data in tabular or graphic form. Survival analysis (with co-factors


[Coinfection with HIV-1 and HTLV-I]
Int Conf AIDS 1989 Jun 4-9; 5:169 (abstract no. A.552)
Patey O, N'Go N, Dublanchet A, Lafaix C; Service des maladies infectieuses et tropicales, Villeneuve St Georges-France
Human immunodeficiency infection in the elderly: a retrospective analysis of 20 patients.
Int Conf AIDS 1989 Jun 4-9; 5:169 (abstract no. A.553)
Thompson J, Kapila R, Tecson F; New Jersey Medical School and VA Hospital, East Orange, N.J., USA
From January 1985 to June 1988 twenty (20) patients over the age 60 years were diagnosed with HIV infection/AIDS according to CDC criteria group I-IV. Their ages ranged from 60-85 years with a mean of 66.1. The group included 18 men and 2 women. The risk factors for the men were Homosexuality, 6/18 (33%), IVDA 3/18 (15


HIV infection in judicial autopsy.
Int Conf AIDS 1989 Jun 4-9; 5:169 (abstract no. A.554)
Barbieri DD, Buchala CM, Guidugli R, Lima LO; Centro de Regerencia e Treinamento da Secretaria de Estado da Saude de Sao Paulo, Brazil
The violent deaths, the suspects deaths and deaths with any delictous evidence must be investigated by a judicial autopsy. Considering the stigmatizing character of AIDS, the high incidence in homosexual and drug abusers and the high prevalence in prisons we expected that suicide, homicides and suspect deaths could occ


Estimates of the AIDS epidemic in Costa Rica, 1989-1993.
Int Conf AIDS 1989 Jun 4-9; 5:170 (abstract no. A.555)
Mata L, Valadez J, Marranghello L; INISA, University of Costa Rica, San Pedro, Costa Rica
To estimate the size and impact of the AIDS epidemic. Five-year projections were obtained by fitting onto four statistical models all cases from epidemic onset in 1984 through December 1988. The data best fitted the power curve. Linear regression, exponential and logarithmic curves produced


Retrovirus infection (HIV-1, HIV-2, HTLV-I) in asymptomatic West Africans living in Spain.
Int Conf AIDS 1989 Jun 4-9; 5:170 (abstract no. A.556)
Soriano V, Tor J, Ribera A, Fernandez JL, Muga R, Foz M; Infectious Diseases and Blood Bank Units, Hospital de Badelona "Germans Trias: Pujol". Universitat Autonoma de Barcelona, Spain
It has been postulated an African origin of human T-lymphotropic retroviruses. While HIV-1 and HIV-2 produced AIDS, the HTLV-I may be the etiologic agent of a subacute myelopathy and an acute T lymphocytic leukemia. However, the worldwide spread of these viruses may occur by infected African persons which ha


[Evaluation of susceptibility to AIDS prevention in university students in Aix-Marseille]
Int Conf AIDS 1989 Jun 4-9; 5:170 (abstract no. A.557)
Beresniak A, Enel P, Sambuc R, San Marco JL; Laboratoire de Sante Publique, Faculte de Medecine, Marseille, France
The HIV epidemic beyond the epicenter: "inner city" epidemiology in a predominantly white suburban population.
Int Conf AIDS 1989 Jun 4-9; 5:170 (abstract no. A.558)
Shepp D, Kaplan M, Smith M, Muggeo C; Cornell Univ. Medical College, North Shore University Hospital, Manhasset, NY, USA
To characterize the epidemiology of HIV infection seen in a university-affiliated teaching hospital located in a suburban setting beyond the New York City limits in Long Island. Hospital and clinic records of the Div. of Infectious Disease were used to create a computerized data base. Referral patte


Regional differences in survival with AIDS among gay white males in the United States.
Int Conf AIDS 1989 Jun 4-9; 5:170 (abstract no. A.559)
Piette J; Brown University, Providence, Rhode Island; USA
To examine geographic variation in survival with AIDS among gay white males in the United States . Survival curves are calculated using data from a census of 24,668 AIDS cases reported to the Centers for Disease Control by 10/3/88. Analyses are presented by region and controlling for the presence of


Possibilities of forecasting HIV spread in large populations. A modelling tool for decision makers.
Int Conf AIDS 1989 Jun 4-9; 5:170 (abstract no. A.560)
Koch MG, Dorner D, Gonzalez JJ, L'ageStehr J, Davidsen P, VonWelck U; Vardcentralen, S-546 00 Karlsborg, Sweden
In comparison between different methods of forecasting the development of an epidemic, computer based simulation techniques are well established and show several advantages, among them high speed, flexibility, transparency, and reproducibility. The program AIDS Spread Simulations and Projections (ASSP) is a modelling t


Correlation of incubation period and progression to disease in HIV carriers.
Int Conf AIDS 1989 Jun 4-9; 5:171 (abstract no. A.561)
Koch MG, Davidsen P, VonWelck U, Gonzalez JJ; Vardcentralen, S-546 00 Karlsborg, Sweden
Comparing about 50 different clinical follow-up studies from various regions in the world, we tried to define the progression rates of HIV infected persons to AIDS. The main problem is that different patient groups never are fully equivalent concerning important variables as their distribution into age and risk categor


HIV seroprevalence at Cook County Hospital, Chicago: a two-year follow-up.
Int Conf AIDS 1989 Jun 4-9; 5:171 (abstract no. A.562)
Seibert D, Tsui P, Cohen M, Hamb A, Sherer R; Cook County Hospital AIDS Prevention Services, Cook County Jail. Chicago, Il, USA
OBJECTIVES: To determine the prevalence of HIV infection among persons at risk of HIV infection at Cook County Hospital, Chicago, in 1987 and 1988, and to compare trends among groups at risk. From 1/1/88 to 12/31/88, 2,084 clients received HIV antibody counseling. Demographics: 42% women, 58% men; 69% black, 1


Women with AIDS: a continuing study 1988.
Int Conf AIDS 1989 Jun 4-9; 5:171 (abstract no. A.563)
Kloser P, Bais P, Lynch A, Lombardo J, Kapila R; University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA
To describe the epidemiology and natural history of HIV infection in women in Newark, New Jersey. This is a continuation of our study of women with HIV disease started in 1980. The addition of 174 new cases in 1988 makes a total of 538 women seen with HIV infection at our facility. The wome


Survey of streetwalking prostitutes in New York City for anti-HIV-1 antibodies.
Int Conf AIDS 1989 Jun 4-9; 5:171 (abstract no. A.564)
Wallace JI, Beatrice S; Foundation for Research on Sexually Transmitted Diseases, New York, NY, USA
To determine the rates of HIV-1 exposure in streetwalking prostitutes of New York. In 1985-1988 prostitutes working on the streets of New York City were tested for anti-HIV-1 antibodies. Blood was drawn on-site, and was tested for antibodies by ELISA with Western Blot confirmation. The women were qu


Effect of age on AIDS attack rate in hemophilics in California.
Int Conf AIDS 1989 Jun 4-9; 5:171 (abstract no. A.565)
Gomperts E, Holman R, Jason J, Evatt B, Addiego J, Hartman G, Lewis B, Glader B, Katz J, Dietrich S, et al; Childrens Hospital of Los Angeles, Los Angeles, California, USA
Comprehensive Care is provided to 90% of hemophiliacs in California by 13 centers. For the year 1987, these centers reported on patient HIV antibody status, age of patient, level of clotting factor deficiency and hemophilia type. The number of AIDS cases in California for the purposes of this study, was that reported t


Prevalence of anti-HIV in i.v. drug users of Latina Province, Italy.
Int Conf AIDS 1989 Jun 4-9; 5:171 (abstract no. A.566)
Perroni L, LeFoche L, Mercurio V, Tacconi L, Zanini R, Soscia F; Dept. of Infectious Diseases, Latina General Hospital, Latina. Italy
To investigate the prevalence of HIV infection in i.v. drug users (i.v.d.u.) and to assess the distribution of other known risk factors. All the i.v.d.u. attending public methadone maintenance clinics in the province of Latina, were offered the HIV antibody test. Subjects repeatedly HIV positive (El


36 months follow-up of HIV-1 seropositive individuals.
Int Conf AIDS 1989 Jun 4-9; 5:172 (abstract no. A.567)
Mezzaroma I, Papetti C, Pesce AM, D'Offizi GD, Pinter E, Luzi G, Aiuti F; Dept. of Allergy and Clinical Immunology, University of Rome "La Sapienza", Rome, Italy
- To evaluate the re-classification risk in HIV-1 seropositive patients at various clinical stages according to the CDC system. - Patients belonging to at risk categories were included: 25 homosexuals, 211 drug addicts, 22 heterosexuals. They were classified at the first medical check according to t


Heterosexual transmission of HIV infection in a group of population of Madrid City.
Int Conf AIDS 1989 Jun 4-9; 5:172 (abstract no. A.569)
Ortiz C, Babin F, Andreu P, Bru F, Pascual I, Colomo C; C.P.S. Centro, Madrid Council, Madrid, Spain
Epidemiological study of HIV infection in 318 subjects with the only risk of heterosexual transmission. Computerized data of Internal Medicine and Dermatology Units of the Clinic were used for the analysis. Twenty two social and sanitary parameters of 318 patients (51 men and 267 women) were followe


Safe and unsafe sexual practices among homosexual men, and the risk of HIV infection.
Int Conf AIDS 1989 Jun 4-9; 5:172 (abstract no. A.570)
Messiah A, Bucquet D, Rouzioux C, Mettetal JF; INSERM, Hopital Necker, Paris, France
To assess the risk of HIV infection among homosexual men, with regard to safe and unsafe sexual practices. Cross-sectional study among 300 homosexual outpatients of general practitioners and venerologists of the Paris area. The subjects were of unknown or of previously negative serological status. B


[IM-9 classification for HIV infections in the french experience of hospital morbidity]
Int Conf AIDS 1989 Jun 4-9; 5:172 (abstract no. A.571)
Boulay F, Pibarot ML, Jestin C, Laporte A, Brunet JB; Direction des Hopitaux, Paris, France
Evaluation of a pediatric AIDS outpatient program.
Int Conf AIDS 1989 Jun 4-9; 5:172 (abstract no. A.572)
Perez-Alvarez T, Merodio C, Babin F, Andreu P, Quintero Y, Vivar P; C.P.S. Centro. Madrid Council. Spain
To evaluate the children s AIDS program carried out in an outpatient clinic located in the Centro district of Madrid city. 130 children ranging from the age of 15 days to 13 years were studied. Biological and psychosocial parameters were analiyed. 108 children (83%) were seronegative and 22


First case of HIV1/HIV2 infection in Cameroon.
Int Conf AIDS 1989 Jun 4-9; 5:173 (abstract no. A.573)
Kaptue L, Zekeng L, Ngu K, Ouattara A, Monny-Lobe M, Salla R; National AIDS Committee Yaounde, Cameroon
To report the first case of HIV1 and HIV2 infection diagnosed in a Cameroonian patient. Up till June 1988, 6 000 sera were screened for HIV2 antibodies and all were found negative. Systematic screening of patients referred to the University Teaching Hospital, using Elisa test (Behring HIV1 and Elavi


HIV spread in prostitute population in Toulouse (France).
Int Conf AIDS 1989 Jun 4-9; 5:173 (abstract no. A.574)
Gayet-Mengelle C, Puel J, Averous S, Bazex J; Laboratoire de Virologie, CHU Purpan, Toulouse, France
To assess the risk of contamination through prostitution (male or female) in our city. We systematically screened anti HIV-1 antibodies in 97 female prostitutes (9 coming from Ghana ) and 16 transvestites or transsexuals, regularly consulting at the Venereal Diseases Centre since May 1985, to Januar


The new case definition criteria, its impact on epidemiological surveillance in Spain.
Int Conf AIDS 1989 Jun 4-9; 5:173 (abstract no. A.575)
De Andres R, Tello O, Medrano MJ; Secretaria General del Plan Nacional sobre el SIDA, Madrid, Spain
Cumulative AIDS cases in Spain on date December 21st. 1988 are 2165. Modifications of case definition criteria for reporting AIDS were undertaken in August 1987 by CDC, accepted by WHO in September and applied by the European countries since January 1st 1988. We have studied the impact of these new criteria of case def


Prevalence of different retrovirus in Spanish intravenous drug users during 1.987-1.988. Clinical findings of seropositives.
Int Conf AIDS 1989 Jun 4-9; 5:173 (abstract no. A.576)
Contreras G, Garcia Saiz A, Vallhonrat E, Varela JM, Peres Alvarez L, Najera R; Instituto de Salud Carlos III, Madrid, Spain
- To analyze the seroprevalence of HIV-2 and HTLV-I in Spanish intravenous drug users (IVDA) and the clinical findings of seropositives to HIV-1 in relationships to the antigenemia status. We determine as well -- the incidence of coinfection with other infectious agents. - Sera collected from 4.269


Control of HIV transmission in the national blood bank in Mali.
Int Conf AIDS 1989 Jun 4-9; 5:173 (abstract no. A.577)
Maiga MK, Traore S, Guindo A, Fofana O; Comite de lutte scientifique et technique contre le SIDA, Bamako, Mali
Since the beginning of the national AIDS program in Mali in 1987, the national blood bank was one of the strategic points for detection, prevention of the transmission of the human retrovirus and the follow up of the prevalence of HIV infection among blood donors. Blood donation was performed from pregnant women, young


The new case definition criteria, its impact on epidemiological surveillance in Spain.
Int Conf AIDS 1989 Jun 4-9; 5:173 (abstract no. A.578)
De Andres, Tello O, Medrano MJ; Secretaria General del Plan Nacional sobre el SIDA, Madrid, Spain
Cumulative AIDS cases in Spain on date December 21st. 1988 are 2165. Modifications of case definition criteria for reporting AIDS were undertaken in August 1987 by CDC, accepted by WHO in September and applied by the European countries since January 1st 1988. We have studied the impact of these new criteria of case def


AIDS in the Nordic countries - prevention and control.
Int Conf AIDS 1989 Jun 4-9; 5:174 (abstract no. A.579)
Westphal-Christensen B, Bjorner J, Eriksson B, Krasnik A; Danish Institute for Health and Nursing Research, Copenhagen, Denmark
Psychological, social, administrative and political aspects of AIDS in the Nordic countries have been reviewed by the Nordic School of Public Health. As expected, the countries appear quite similar. Specified AIDS-commissions have been established, closely linked to governments. Specific target groups like homosexuals


Risk profile for HIV infection at a sexually transmitted disease clinic.
Int Conf AIDS 1989 Jun 4-9; 5:174 (abstract no. A.580)
Beidas S, LoConte J, Byrnes D; Saint Michael's Medical Center, Newark, N.J. USA
To determine HIV risk profile of HIV infected individuals in an STD clinic population, and coexisting STD s at time of diagnosis. METHOD: One hundred and forty patients were counselled and tested for HIV antibody, at an inner city STD clinic over a 7 month period. Thirteen (9 %) patients tested positive for


Evaluation of a multidisciplinary HIV diagnosis and management center, Sydney, Australia.
Int Conf AIDS 1989 Jun 4-9; 5:174 (abstract no. A.581)
Morlet A, Michelmore H, Turbitt P, Begley K, Gold J; Albion Street (AIDS) Centre, Sydney Hospital, Sydney, Australia
To provide a multidisciplinary diagnosis, ambulatory care and early intervention service for persons infected with HIV. METHOD: The Albion Street (AIDS) Centre, established in March 1985, is staffed by 45 full time professional and support staff including doctors, nurses, counsellors and research officers. T


Viral hepatitis B(HBV) and AIDS in risk communities in the North-East of Argentina (NEA).
Int Conf AIDS 1989 Jun 4-9; 5:174 (abstract no. A.582)
Fay O, Biglione J, Fernandez E, Galindez J, Guagnino L, Navarret N; Centro de Technologia en Salud Publica, UNR, Argentina
To study the attack rate of HBV and HIV in drug addicts (IVDA) and homosexuals (HS), compared with the general population as per samples collected from voluntary blood donors (VBD). Studies were made on samples from communities seeking medical advice in response to COPRES appeal. HBV-carriers were d


Lymphadenopathy is a weak predictor of clinical outcome in HIV infection.
Int Conf AIDS 1989 Jun 4-9; 5:174 (abstract no. A.583)
Lang W, Anderson R, Royce R, Shiboski S; Children's Hospital, San Francisco, CA, USA
To determine the relationship of lymphadenopathy to clinical outcome in HIV infection. Lymphadenopathy was measured by trained examiners in a population-based sample of 385 men from the San Francisco Men s Health Study who were seropositive at entry in Fall 1984. The incidence of symptoms of progres


Diagnosis and mortality trends in an outpatient AIDS clinic.
Int Conf AIDS 1989 Jun 4-9; 5:174 (abstract no. A.584)
Keyes C, Kelly J, Marte C; Bellevue Hospital Center/Community Health Project NY, NY USA
To review trends in diseases of diagnosis and death in a community based primary care AIDS clinic population as a basis for improved management. All cases (169) of AIDS diagnosed from 1/1/86 to 1/1/89 in a primary care out-patient AIDS clinic were reviewed for index diagnosis, year of diagnosis, dia


Serological trend for 22 Mexican homosexual patients that are symptomatic and asymptomatic seropositive.
Int Conf AIDS 1989 Jun 4-9; 5:175 (abstract no. A.585)
Morales C, Romero M, Delgadillo S, Dominguez J; Centro Nacional de la Transfusion Sanguinea, Mexico, D.F., Mexico
To determine the presence of HIV Ag and the absence of p24 for one full year in 22 patients that were positive asymptomatic and symptomatic. The study was done in 16 asymptomatic patients, 3 in phase I, 2 in - phase II, and 1 with ARC. A determination of ENV/CORE and detection of HIV Ag in serum was


Prevalence of HBV and HDV markers in patients infected with HIV in Buenos Aires.
Int Conf AIDS 1989 Jun 4-9; 5:175 (abstract no. A.586)
Fainboim H, Benetucci J, Astarloa L, Gomez N, Castello T, Schulkin S, Compagnucci A, da Bouza J, Corti M, Diaz Lestrem M; Hospital F.J. Muniz. Buenos Aires. Argentina
The purpose of this study is to evaluate the prevalence of HBV and HDV markers in a group of patients infected with HIV. 96 patients (70 males-26 females between 15 and 53 years) were studied. 72 were IVDA, 17 homosexual, 6 partners of HIV(+) patients and 1 hemophilic. The HIV seropositivity was det


[High prevalence of HTLV-I and low prevalence of HIV in ivory coast lepers]
Int Conf AIDS 1989 Jun 4-9; 5:175 (abstract no. A.587)
Sangare A, Verdier M, Sorro B, Gershy-Damet GM, Leonard G, Francois D; Institut Pasteur et, Cote d'Ivoire
Epidemiologic surveillance of human immunodeficiency virus in the industrial city of Siberia.
Int Conf AIDS 1989 Jun 4-9; 5:175 (abstract no. A.588)
Denisenko BA, Bulwachter LA, Malphanov AD; Head, Chair of Therapy, Institute for Advanced Medical Studies, Novokuznetsk, USSR
Investigation of the epidemiology of human immunodeficiency virus (HIV) is based on case detection in the Centers for Disease Control. As of December 1988, 45,807 cases of HIV have been tested in non-endemic areas. In the first stage of our investigation the inquiry-test data for all persons with clinically manifested


AIDS: knowledge and attitudes among different ethnic groups.
Int Conf AIDS 1989 Jun 4-9; 5:175 (abstract no. A.589)
Eskander GS, Jahan M, Carter R; Meharry Medical College, Nashville, Tennessee, USA
AIDS is an international as well as a national public health problem. Since the identification of acquired immunodeficiency syndrome (AIDS) in 1981, the number of cases has steadily increased throughout the world. The World Health Organization estimated that the world total of AIDS cases will reach up to three million


AIDS on Long Island.
Int Conf AIDS 1989 Jun 4-9; 5:175 (abstract no. A.590)
Agins BD, Montgomery N, Forlenza S; Nassau County Medical Center, East Meadow, New York
To describe the characteristics of the AIDS epidemic on suburban Long Island. A retrospective review of epidemiologic and demographic data from the records of AIDS patients seen at Nassau County Medical Center (NCMC) during 1987 and 1988 was performed. Nassau County is the suburban area wit


Electronic reporting system for AIDS surveillance in Canada.
Int Conf AIDS 1989 Jun 4-9; 5:176 (abstract no. A.591)
Nault P, Elmslie K; Federal Centre for AIDS, Health Protection Branch, Ottawa, Ontario, Canada
To describe the development of an electronic system for national reporting of AIDS surveillance data. AIDS is a reportable condition in all provinces and territories in Canada . Through collaborative efforts between the provincial/territorial Ministries of Health and National Health and Welfare, a s


An update on HIV-seroprevalence studies in the Netherlands.
Int Conf AIDS 1989 Jun 4-9; 5:176 (abstract no. A.593)
Lumey LH, Houweling H, Jager JC; Natl Inst Publ Hlth Env Hyg (RIVM), Bilthoven, the Netherlands
Currently available data on HIV seroprevalence among selected groups in the Netherlands are inadequate to assess the spread of the epidemic among homosexual men, intravenous drug users or the population-at-large. So far, only volunteer studies have been conducted. Additional surveys are required: 1) to establish a base


[The demand for HIV serology examination in general medicine]
Int Conf AIDS 1989 Jun 4-9; 5:176 (abstract no. A.595)
Van Casteren V, Stroobant A; Institut D'hygiene ET D'epidemiologie, Bruxelles, Belgique
Prevalence of HIV-1 antibody among gay men in the UK: differences between clinic attenders and non-attenders.
Int Conf AIDS 1989 Jun 4-9; 5:176 (abstract no. A.597)
Davies P, Coxon AP, McManus TJ, Sutherland S; Project SIGMA, South Bank Polytechnic, London, UK
To estimate the prevalence of HIV-1 antibody in the homosexually active male population of England and Wales and, bearing in mind that current estimates of prevalence and possible spread are based on those attending STD clinics, to estimate the differences between clinic attenders and non-attenders.


Outreach to IV drug users and sex partners: satisfactions and dissatisfactions of outreach workers.
Int Conf AIDS 1989 Jun 4-9; 5:177 (abstract no. A.598)
Stull C, Deren S, Graves F, Sufian M, Friedman SR, Tross S; Narcotic and Drug Research Inc., New York, New York, USA
Ex-addict workers are widely used for AIDS outreach to IVDUs and their sex partners. Our objective is to describe the characteristics of indigenous ex-addict outreach workers hired to provide AIDS prevention and education information to intravenous drug users and their sex partners in New York City, and to d


Decontamination of an HIV contaminated CPR manikin.
Int Conf AIDS 1989 Jun 4-9; 5:177 (abstract no. A.599)
Corless I, Lisker A, Buckheit RW, Smiley ML, Langlois AJ, Weinhold K; University of North Carolina-Chapel Hill, North Carolina
Manikins are used widely for cardiopulmonary resuscitation (CPR) training. Simulating a worst-case scenario , a manikin was contaminated in different experiments with either cell-free or cell associated HIV-1. Recommended decontamination procedures were compromised by maintaining a wet surface for 10 or 5 se


Radioresistance of HIV-1 in a bone allograft model.
Int Conf AIDS 1989 Jun 4-9; 5:177 (abstract no. A.600)
Conway B, Tomford WW, Hirsch MS, Schooley RT; Infectious Diseases Unit, Massachusetts General Hospital Boston, MA, USA
To study the feasibility of inactivating HIV-1 in bone graft material by gamma irradiation. Serial dilutions of HIV-1 (10(1)-10(6) TCID50/ml) were subjected to gamma irradiation under conditions simulating those within a bone allograft. Radiated and control specimens were cultured on H9 cells which


Resistance of human immunodeficiency virus to disinfectants and fixatives.
Int Conf AIDS 1989 Jun 4-9; 5:177 (abstract no. A.601)
Hanson P, Gor D, Jeffries DJ, Collins JV; Brompton and St. Stephen's Hospitals, London
Previous reports that HIV is susceptible to disinfectants are based on suspension tests. We tested 70% alcohol (IMS, Alcohols Ltd.; final concentration ethanol 63.8%, methanol 3.5%, water 26.5% v/v), acetone, 1% and 2% alkaline glutaraldehyde (Cidex, Surgikos Ltd) against HIV dried on a surface. The following inocula w


Potential for HIV transmission via blood glucose monitoring devices.
Int Conf AIDS 1989 Jun 4-9; 5:177 (abstract no. A.602)
Shalit P, Brennan C, Murphy V, Hooton T; University of Washington, Harborview Medical Center, Seattle, Washington, USA
We are following a 43 year old HIV-positive insulin-dependent diabetic woman whose only known exposure to HIV was from vaginal intercourse with her HIV-positive bisexual husband. The woman indicated to us that since 1981 she has screened family members, friends, and relatives for diabetes by performing fingerstick gluc


Similar magnitude of the AIDS epidemics among homosexual men in Costa Rica and in the United States.
Int Conf AIDS 1989 Jun 4-9; 5:178 (abstract no. A.603)
Mata L, Valadez J; INISA, University of Costa Rica, San Pedro, Costa Rica
To compare the incidence of AIDS in homosexual and bisexual men in Costa Rica , with that in the United States , from the year the epidemics were first recognized ( year one ). Year one was 1981 for the U.S.A. and 1985 for Costa Rica. Cumulative incidence rates (per million) were calculated using th


Heterosexual contact patterns of 429 pregnant non-IV drug using women in the South Bronx, NY, in 1988.
Int Conf AIDS 1989 Jun 4-9; 5:178 (abstract no. A.604)
Drucker E, Schoenbaum EE, Webber MP, Stern LS, Vermund SH, Gayle H; Montefiore Medical Center, Bronx, NY, USA
To quantify the probability of heterosexual exposure to HIV-1 for non-IV drug using sexually active women in an area with high levels of HIV-1 (especially among males age 25-34); and to explain known differences in seroprevalence by age, geography, and race/ethnicity among women of childbearing age. METHOD:


Multiple group models with heterogeneous mixing for the transmission dynamics of HIV/AIDS.
Int Conf AIDS 1989 Jun 4-9; 5:178 (abstract no. A.605)
Castillo-Chavez C, Cooke K, Huang W, Levin SA; Cornell University, Ithaca, NY, US
Specify ways of constructing multiple group models that take into consideration the social/sexual structure of a population; to present analytical results for single and multiple group models for the spread of HIV/AIDS; and to discuss the consequences of the nonstandard behavior observed in the multiple grou


Perinatal and heterosexual transmission through HIV-positive women.
Int Conf AIDS 1989 Jun 4-9; 5:178 (abstract no. A.606)
Rehmet S, Staszewski S, Wegerich B, Kreuz W, Stille W; Zentrum der Inneren Medizin, Zentrum der Kinderheilkunde, Universitatsklinik Frankfurt, FRG
Since 1984, we have examined HIV-infected women and their partners in order to gain information on infectivity, perinatal & heterosexual transmission rates, and possible relations between these factors. 44 Women examined in this period had born a total of 47 children since their HIV infection. 10 children are posit


Additional risk factors in HIV positive persons as monitored by a national HIV notification system.
Int Conf AIDS 1989 Jun 4-9; 5:178 (abstract no. A.607)
Hasseltvedt V, Lystad A, Nilsen O; National Institute of Public Health, Oslo, Norway
To study additional risk factors (e.g. sexual contact with person known to be HIV positive, sexual contact in a hyperendemic country, sexual contact with prostitutes), regarding persons notified as HIV positive where transmission category is known. METHOD: The Department of Infectious Disease Control (DIDC),


Comparison of survival experiences of New York and California Medicaid AIDS patients.
Int Conf AIDS 1989 Jun 4-9; 5:178 (abstract no. A.608)
Markson L, Keyes M, Turner B; Jefferson Medical College, Philadelphia, PA
To compare the survival experiences, hospital length of stay and costs of care of Medicaid AIDS patients in New York and California adjusting for severity level at the first recorded AIDS hospitalization. Medicaid claims for AIDS patients in New York and California from 1983-1987 are linked in order


Predicting in-hospital mortality for AIDS patients: a validated model.
Int Conf AIDS 1989 Jun 4-9; 5:179 (abstract no. A.609)
Grover SA, Gilmore N, Falutz J, Tsoukas C, Coupal L, Fakhry R; Montreal General Hospital, McGill University, Montreal, PQ
Estimating prognosis for a hospitalized AIDS patient is essential for optimal clinical management. We developed a prediction model for in-hospital mortality using admission data abstracted from 128 patient admissions to the Royal Victoria Hospital (RVH). This model was subsequently validated on 62 patient admissions to


Evolution of the clinical and laboratory parameters of one patient with HIV infection in the first year after his documented date of seroconversion.
Int Conf AIDS 1989 Jun 4-9; 5:179 (abstract no. A.612)
Georgopoulou SA, Ploumidis GM, Roumeliotou AN, Papadopoulos AI, Stergiou GD; 1st IKA Hospital, Athens, Greece
To present the pattern of changes in the clinical and laboratory findings observed during the first year after the date of seroconversion. METHOD: A HIV-seronegative patient was admitted to our hospital suffering from a mononucleosis - like syndrome. On the 23rd day of his hospitalization and while he was fr


Influence of HIV on prison inmate (PI) dialysis (D) trends.
Int Conf AIDS 1989 Jun 4-9; 5:179 (abstract no. A.613)
Glaser J, Kaplan J, Laio P, Kleiner M, Sudberg L, McGinn J; Richmond Memorial & Staten Island Hospitals, SI, NY, USA
PURPOSE: To assess the influence of HIV on PI D trends at AKCF. Hospital and D unit record review. From 7/82 thru 12/88, 64 male NY State PIs underwent D, including 50 IVDUs and 14 non-IVDUs. Early (7/82-12/84) and later (1/85-12/88) D experiences for IVDUs were compared. No difference in: % of pts. w


HIV infection in patients attending a hospital based sexually transmitted diseases clinic.
Int Conf AIDS 1989 Jun 4-9; 5:179 (abstract no. A.614)
DeHovitz J, Freedman P, Bastien A, Norat Y; AIDS Prevention Center, SUNY - HSC @ Brooklyn, USA
To determine HIV seroprevalence in patients who are attending STD clinic in a high prevalence area. All patients attending an urban hospital-based STD clinic were offered HIV-1 testing in a period between 8/88 and 12/88. Patients were given pretest, with posttest counseling scheduled two weeks follo


Risks associated with acquiring chancroid genital ulcerative disease and HIV infection: a case control study.
Int Conf AIDS 1989 Jun 4-9; 5:180 (abstract no. A.615)
McLaughlin M, Wilkes M, Blum S, Hermoso A, Schmid G; New York City Department of Health, NY, NY, USA
To identify risks associated with acquiring chancroid and to evaluate the seroprevalence of human immunodeficiency virus (HIV) infection among men presenting with chancroid and gonorrhea to a New York City Department of Health sexually transmitted diseases clinic. This case-control study was perform


Loss of serologic and virologic markers of HIV-1 in asymptomatic HIV-1 infected homosexual men.
Int Conf AIDS 1989 Jun 4-9; 5:180 (abstract no. A.616)
Farzadegan H, Wolinsky S, Sninsky J, Kwok S, Rinaldo C, Phair J, Kaslow R, Saah A; Multicenter AIDS Cohort Study (MACS), Bethesda, MD, USA
To follow virological and serological changes in 4 asymptomatic homosexual men who seroreverted from positive to negative for HIV-1 during the initial 2-2.5 yrs of evaluation. Peripheral blood mononuclear cells (PBMCs) of these participants showed detectable HIV-1 DNA by the polymerase chain reaction (PCR) m


HIV infection in lorry drivers and their assistants in eastern Africa.
Int Conf AIDS 1989 Jun 4-9; 5:180 (abstract no. A.617)
Carswell JW, Namaara W, Lloyd G, Howells J; Family Health International, Research Triangle Park, North Carolina, USA
To quantify prevalence of HIV infection among long distance lorry drivers, and their assistants, in eastern Africa. Sixty-eight lorry drivers and their assistants were tested for HIV while in Kampala, Uganda , in October 1986. Data were collected on travel history, prostitute contact and history of


Risk of infection by human immunodeficiency virus in health care workers (HCW).
Int Conf AIDS 1989 Jun 4-9; 5:180 (abstract no. A.618)
Hernandez E, Gatell JM, Puyuelo T, Barrera JM, Pumarola T; Occupational Health Service. Infec. Diseases Unit. Haemostasy Unit. Hospital Clinic. Barcelona. Spain.
To evaluate the risk of occupational transmission of HIV. We have prospectively followed a cohort of 76 HCW who reported at least one episode of direct exposure to body fluids of HIV infected patients (presence of antibodies against the HIV by at least two ELISA test and confirmed by Western Blot in


AIDS surveillance in Sichuan, China.
Int Conf AIDS 1989 Jun 4-9; 5:180 (abstract no. A.619)
Dongyou Y, Chen L, Lu B, Deng P; Health and Anti-Epidemic Centre of Sichuan Province, Chengdu, Sichuan Province 610031, People's Republic of China
To monitor introduction of AIDS from the outside world. We used antigen slides of T-cell line infected with HIV and indirect immunofluorescent antibody technique (IFA) for the detection of antibodies against HIV in sera of persons at high risk. So far, in our laboratory 1,327 sera collected


The presence of tumor necrosis factor (TNF) in serum and in lymphocyte cultures of HIV-positive and negative homosexual subjects.
Int Conf AIDS 1989 Jun 4-9; 5:180 (abstract no. A.620)
Buimovici-Klein E, Lange M, Mohan D, Sonnabend JA, Grieco MH, Cooper LZ; St. Luke's-Roosevelt Hospital Center, Columbia University, New York, New York 10025
Recent reports have described the presence of TNF in the sera of HIV-positive symptomatic (ARC, AIDS) individuals. We, therefore, attempted to correlate the presence of TNF in serum and in the supernatants of lymphocyte cultures with the presence of various viruses isolated from different body sites in HIV p


The search for a cofactor in AIDS-related Kaposi's sarcoma (KS): assessment of nitrite inhalant use in studies of homosexual men with AIDS.
Int Conf AIDS 1989 Jun 4-9; 5:181 (abstract no. A.621)
Haverkos H, Drotman DP; National Institute on Drug Abuse, Rockville, Maryland, USA
The epidemiology of KS in AIDS (the concentration among white homosexual men and the declining proportion of cases) suggests that HIV may not act alone as its cause. In transfusion-acquired AIDS from donors in whom KS subsequently developed, KS is rare, suggesting that a specific strain of HIV is not responsible. The u


Occurrence and prognostic value of AIDS-related clinical manifestations in HIV-1 seropositive homosexual men.
Int Conf AIDS 1989 Jun 4-9; 5:181 (abstract no. A.622)
Kaslow RA, Blackwelder W, Visscher B, Friedman H, Anderson R, Fox R, MacDonell K, Kuo V; Multicenter AIDS Cohort Study (MACS). Bethesda, MD, USA
To use a clinical index to quantify early clinical progression of HIV-1 infection and determine the prognostic value of a single examination. A clinical index derived from early symptoms and signs of HIV-1 infection was used to score men based on data collected semiannually. Proportions of men with


Detection and quantification of HIV-1 antibodies in semen.
Int Conf AIDS 1989 Jun 4-9; 5:181 (abstract no. A.623)
Wolff H, Martinez A, Politch J, Saltzman S, Mayer K, Anderson DJ; Harvard Medical School, Boston, MA
To measure levels of HIV-1 antibodies (Abs) of IgG, IgA and IgM subclasses in human seminal plasma (SP) from HIV seropositive men, and to compare titers to those in matched serum. Semen was obtained from 28 HIV-1 seropositive men and from 16 seronegative men. Corresponding serum samples were obtaine


Electron microscopic (EM) analysis of semen from HIV seropositive males.
Int Conf AIDS 1989 Jun 4-9; 5:181 (abstract no. A.624)
Pudney J, Wolff H, Anderson D; Harvard Medical School, Boston, MA, USA
To determine if the structural composition of semen changes following infection with HIV. Transmission EM analysis of semen samples from HIV+ males (n=20). Normal semen contains spermatozoa plus a variable population of round cells composed of white blood cells (WBC) and immature germ cells


Quantification of CD4 lymphocytes, macrophages and HIV antigen levels in vaginal secretions of HIV+ women.
Int Conf AIDS 1989 Jun 4-9; 5:181 (abstract no. A.625)
Hill JA, Carpenter CC, Martinez A, Politch JA, Mayer K, Anderson DJ; Harvard Medical School, Boston, MA
To quantitate HIV host cells (HHC) and HIV antigen in vaginal secretions (VS) of HIV seronegative women (n=5) and asymptomatic HIV+ women (n=7), women with CDC IV non AIDS (n=5), and women with AIDS (n=6). 30 VS were obtained from 18 HIV+ women and 20 VS from 5 low risk HIV- women. Cell smears were


Pets and HIV disease; a survey of providers' knowledge and attitudes.
Int Conf AIDS 1989 Jun 4-9; 5:181 (abstract no. A.626)
Gorczyca K, Abrams D, Carmack B; Pets Are Wonderful Support, San Francisco, California, USA
OBJECTIVES: To assess the knowledge base of physicians expert in the care of individuals with HIV infection with regard to their understanding of zoonotic diseases and their attitudes regarding the interactions of their patients and their pets. A 14 question survey was distributed to membership attending the S


A community-based HIV assessment unit: how does it work?
Int Conf AIDS 1989 Jun 4-9; 5:182 (abstract no. A.627)
Morgan A, Davis I, Israni P, Ramis CM, Norris B, Barnwell M; Woodhull Medical & Mental Health Center, Brooklyn, NY, USA
To describe how patients at high-risk for HIV infection are evaluated and treated by an interdisciplinary team of providers at a community-based HIV Assessment Unit. METHODS & Woodhull Medical & Mental Health Center, a division of NYC Health and Hospitals Corporation, is a large municipal ho


Evaluation of compliance rate in a clinic serving minority and low income communities.
Int Conf AIDS 1989 Jun 4-9; 5:182 (abstract no. A.628)
Davis I, Leibel J, Paroski P, Laqueur P; Woodhull Medical and Mental Health Center, Brooklyn, NY, USA
To determine compliance rates for HIV-seropositive persons in a socioculturally sensitive clinic (SSC) setting from communities that are considered traditionally noncompliant . METHOD: Missed appointments rates were compared between the SSC and the ambulatory care network (ACN). The overall broken appointmen


Prevalence of antibodies against HIV-1 and HTLV-I in African sera samples collected during the 1960's.
Int Conf AIDS 1989 Jun 4-9; 5:182 (abstract no. A.629)
Frenkl T, McGhee B, Lewinski C, Longiaru M, Nair RN, Pottathil R; Roche Diagnostic Systems, Inc., Nutley, New Jersey, USA
To study the prevalence of HIV-1 and HTLV-I infections during the 1960 s in Ghana among the Akan, Ga-Adangbe, and Ewe tribes. 404 archived sera samples from Ghana collected as early as 1960 were used in this study. Sera was screened for the presence of antibodies against HIV-1 and HTLV-I using Roche


Training the health care professional: the AIDS Regional Education and Training Centers Program of the Health Resources and Services Administration (HRSA).
Int Conf AIDS 1989 Jun 4-9; 5:182 (abstract no. A.630)
Horner J, Heffron P, Martell B, Moore D, Macher A; Division of Medicine, Bureau of Health Professions, HRSA, United States Public Health Service, Rockville, Maryland, USA
To establish regional AIDS education centers that will provide multidisciplinary training for health care professionals. With a projected cumulative total of more than 300,000 AIDS cases by 1992, it is essential that health care providers be trained in the diagnosis, management and treatment of HIV-


Increased susceptibility of unstimulated peripheral blood mononuclear cells (PBMC) and CD8+ cell-depleted PBMC to in vitro infection with HIV after ingestion of 2 to 4 beers.
Int Conf AIDS 1989 Jun 4-9; 5:182 (abstract no. A.631)
Bagasra O, Lischner HW, Kajdacsy-Balla A; Univ. of Med. & Dent. of New Jersey, Camden, NJ, USA
To determine the duration of the previously described effects of acute ethanol ingestion on HIV infection of PBMC in vitro (FASEB J 2:A831, 1988) and the influence of removal of CD8+ cells on these phenomena. PBMC isolated from 3 healthy non-alcoholic volunteers before and almost daily after consump


The opportunists in human AIDS (HAIDS) are zoonotic.
Int Conf AIDS 1989 Jun 4-9; 5:182 (abstract no. A.632)
Torres-Anjel MJ, Rueda RH; Univ. of MO Columbia, USA
To explore animal diseases and animal products with respect to HAIDS. MATERIALS: The opportunists associated to HAIDS were searched in the AIDSLINE database with GRATEFUL MED (TM) software and scrutinized vis-a-vis the concept of zoonoses (1). The number of publications devoted to each were recorded (in pare


Epidemiologic study of children of HIV infected women in primary health care.
Int Conf AIDS 1989 Jun 4-9; 5:183 (abstract no. A.633)
Perez-Alvarez T, Merodio C, Babin F, Ortiz C, Colomo C, Sastre J; C.P.S. Centro. Madrid Council. Spain
To show social and sanitary variables influencing HIV positive children and HIV negative children, of HIV infected women before pregnancy. Analytic and descriptive study of 40 social and sanitary parameters obtained of cases studied in the pediatric unit between January 87 and January 89. C


HIV-2 infection in Sardinia.
Int Conf AIDS 1989 Jun 4-9; 5:183 (abstract no. A.634)
Pintus A, Piras S, Contu L, Pitzus F; Istituto di Clinica Medica, Universita di Cagliari, Italy
HIV-2 infection has been found only in few cases in Italy but no data are, by now, known about the presence or absence of this virus in Sardinia where there are about 15.000 drug abusers (DA) on 1.500.000 inhabitants and 1500 beta-thalassemic (BT) patients. Considering that AIDS cases are rapidly increasing


[Heterosexual transmission of HIV: hospital surveillance in Aquintaine, France - 1985-88]
Int Conf AIDS 1989 Jun 4-9; 5:183 (abstract no. A.635)
Poumerol G, Chaslerie A, Morlat P, Lacoste D, Dupon M; Department d'Informatique Medicale, Universite de Bordeaux II, Bordeaux, France
[Epidemiological characteristics of new HIV seropositives in central-western France: evaluation of incidence and behavior]
Int Conf AIDS 1989 Jun 4-9; 5:183 (abstract no. A.636)
Marchand S, Choutet P; CHRU Bretonneau, 37044 Tours France
Profile of HIV-infected patients at San Francisco General Hospital outpatient clinics.
Int Conf AIDS 1989 Jun 4-9; 5:183 (abstract no. A.637)
Wong RJ, Gumbley-Smith D, Volberding P; Department of Medicine, San Francisco General Hospital, San Francisco, California USA.
To document characteristics of patients who receive medical care at SFGH AIDS adult outpatient clinics. Of 2000 patients receiving primary care at SFGH AIDS clinics, 100 charts were randomly selected from a computer list of visits from December 8 to 13, 1988. There were 92 males and 8 femal


A community-based model for primary care at an HIV antibody alternate test site.
Int Conf AIDS 1989 Jun 4-9; 5:183 (abstract no. A.638)
Howard J, Mahon R, Duynstee S, Walker M, Brooks S; University of California, Irvine, CA, USA
We set up a community-based clinic in Los Angeles at a HIV antibody alternate test site for the medical and psychological evaluation of antibody-positive testees. Health history, physical exam, laboratory tests and psychological assessment were obtained on 1200 subjects from the alternate test site


Health workers for the AIDS epidemic in the USA: what we know and what we need to know.
Int Conf AIDS 1989 Jun 4-9; 5:184 (abstract no. A.639)
Hall T, Dunham N, Wittenberg E, Knickman J; Univ. of Calif./San Francisco, USA
To define available and needed information regarding health worker training and deployment to cope with AIDS. The literature through 1988 was reviewed and 29 persons knowledgeable about different aspects of staff training and utilization were interviewed. More than 100 relevant citations we


Semen banks/embryo banks: potential hazard of HIV transmission: an overview.
Int Conf AIDS 1989 Jun 4-9; 5:481 (abstract no. B.501)
Hafez ES; World Federation of Contraceptive Health, Reproductive Health Center, Surfsong Road, Kiawah, SC, USA
Donor artificial insemination (AID) and in vitro fertilization (IVF) using human fresh semen and cryopreserved/thawed semen from HIV-seropositive or asymptomatic donors play a critical role in HIV transmission. HIV and various strains of STD s can adhere to and penetrate the plasma membrane of human sperm head/midpiece


Contraceptives, HIV infections and heterosexual transmission.
Int Conf AIDS 1989 Jun 4-9; 5:481 (abstract no. B.502)
Hafez S, El Tonsi H, Lofty M; Reproductive Health Center, Kiawah Island, SC, USA
Contraceptive copper IUD s, contraceptive diaphragms, rubber condoms, and spermicides may produce allergic contact dermatitis in sensitized persons. Rubber chemicals may cause condom dermatitis/diaphragm balanitis in rubber sensitive men, and vulvititis/vaginitis in rubber-sensitive women. Dermatitis may be due to sens


[Prospective study of HIV infection in pregnant women: surveillance of 96 patients, 51 infants and 49 families]
Int Conf AIDS 1989 Jun 4-9; 5:481 (abstract no. B.503)
Ciraru-Vigneron N, Nguyen Tan Lung R, Brunner C, Honderlick P, Wautier JL, Ravina JH; Hopital Lariboisiere, Universite Paris VII, Paris, France
HIV infection rates in parturients who receive no prenatal care.
Int Conf AIDS 1989 Jun 4-9; 5:481 (abstract no. B.504)
Killian H, Risi G, James D, Muirhead L, Shields J, Marier R; Department of Infection Control, Charity Hospital, New Orleans, LA, USA
To test the hypothesis that women receiving no prenatal care represent a higher risk group for HIV infection than those who receive regular care at an urban hospital serving primarily indigent patients (Charity Hospital [CH]). All women presenting to the obstetrical clinics of CH are offered HIV tes


Massage for terminally ill AIDS patients.
Int Conf AIDS 1989 Jun 4-9; 5:481 (abstract no. B.505)
Ruebottom A, Lee C, Dryden PJ; Casey House Hospice Inc., Toronto, Ontario, Canada
To describe the pioneering venture of using Registered Massage Therapists (RMTs) in a healthcare institution and to outline the massage techniques and modalities contributing to the care of terminally ill AIDS patients at Casey House. The activities within the scope of practice of RMTs in Ontario ar


Evaluating the outcomes of a linkage system designed to facilitate access for chronically homeless persons to an outpatient AIDS program.
Int Conf AIDS 1989 Jun 4-9; 5:481 (abstract no. B.506)
Hagerty CA, O'Connell JJ; Boston City Hospital, Boston, MA, USA
SIGNIFICANCE: The numbers of known HIV+ residents residing in Boston s shelters has grown from 1, in 1985, to more than 75 in 1988. Chronically homeless constitute 25% of the Aids program patients. Our primary effort has been to broaden AIDS-specific health care to our city s chronically homeless population


Comprehensive out-patient care of HIV-infected patients utilizing a primary care model.
Int Conf AIDS 1989 Jun 4-9; 5:482 (abstract no. B.507)
Anastos K, Soloway B, Ernst J; Bronx-Lebanon Hospital Center, Bronx, New York, USA
To meet the total health needs of HIV infected individuals, of all ages and all states of illness, in a community with very high HIV seroprevalence. METHOD: The establishment of a comprehensive out-patient health care program for HIV-infected individuals. A community hospital in the South Bronx has


AIDS and physical education.
Int Conf AIDS 1989 Jun 4-9; 5:482 (abstract no. B.508)
Freire SV, Machado IZ; Centro Corsini, (CCII), Campinas, Sao Paulo, Brazil
The human is an integral composition of mind and body represented by pleasure and aesthetics, emotions and reason. The body is the very first human experience moment. The individual senses and lives prior to knowing, participating through the body in real life. However the individual is being threatened by the AIDS vir


Long-term follow-up untreated-severe thrombocytopenia (STP) in three HIV infected drug addicts.
Int Conf AIDS 1989 Jun 4-9; 5:482 (abstract no. B.509)
Tural C, Clotet B, Sirera G, Romeu J, Casals A, Tor J, Foz M; Infectious Disease Unit, Hospital de Badalona "Germans Trias i Pujol", Barcelona, Catalonia, Spain
To report the findings and follow-up observed in three seropositive patients who denied any therapeutic approach during a mean period of 18 months (range 27-15). 3 out of 12 HIV seropositive IDAs with severe thrombocytopenia (STP) (platelet count less than 9000/mm(3) and rich marrow aspirate) relate


Fully automated system for the detection and registration of HIV-antibodies in donor blood.
Int Conf AIDS 1989 Jun 4-9; 5:482 (abstract no. B.510)
Reesink H, Koot A, Schram N, Plaisir A, Drewes A; Red Cross Blood Bank, Amsterdam, The Netherlands
To develop a fully automated system for the detection and registration of anti-HIV in donor blood. Anti-HIV tests are done with an ELISA system in microtiter plates (Wellcozyme, Wellcome, UK). The automated system functions as follows: microtiter plates are provided with barcoded labels and position


Hemophiliac population of Costa Rica from 1979 to 1989.
Int Conf AIDS 1989 Jun 4-9; 5:482 (abstract no. B.511)
Taylor L, Montero C, Cordero R, Astua MC, Roy A, Luftig R, Visona KA; Louisiana State University-International Center for Medical Research & Training, (LSU-ICMRT), San Jose, Costa Rica
To analyze the serological profile in the hemophiliac population in Costa Rica . Serum samples stored in the LSU-ICMRT serum bank were tested with anti-HIV ELISA (Abbott HTLV-III), Western Blot (LSU-ICMRT), HIV antigen (vironostika-Organon), IRMA HBsAg and anti-HBs (LSU-ICMRT). Clinical data were ob


Immune activation in HIV positive and negative hemophiliacs.
Int Conf AIDS 1989 Jun 4-9; 5:482 (abstract no. B.512)
Nishida Y, Oura Y, Koyama T, Higuchi M, Kakishita E; Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan
To analyze signs of immune activation observed in hemophiliac patients with and without HIV infection. The absolute CD4 number, percent, CD4/CD8 ratio, Ia positive cell percent and Ig (G, A, M) were measured on a cohort of 41 hemophiliac patients (18 seropositive, 23 seronegative) followed for 5 yea


HIV-infection in hemophiliacs in Argentina.
Int Conf AIDS 1989 Jun 4-9; 5:483 (abstract no. B.513)
Muchinik G, Perez BR, Bouzas MB, Rickard E, Armando E, de Tezanos Pinto M; IIHEMA, Academia Nacional de Medicina, Buenos Aires, Argentina
To describe an update of HIV-infection in hemophilia. HIV antibodies (ab) were detected through EIA (Abbott) and confirmed by means of IFA and ENVACORE (Abbott). A total of 467 hemophiliacs has been studied since November, 1984. TABULAR DATA, SEE ABSTRACT VOLUME. CONCLUSION: Since 1984 and


Findings of indeterminate results to WB (p17, p24, p55) in Mexican normal donors.
Int Conf AIDS 1989 Jun 4-9; 5:483 (abstract no. B.515)
Romero M, Morales C, Dominguez J; Centro Nacional de la Transfusion Sanguinea, Mexico, DF
The previous detection (screening) which is done mandatory by law to the blood drawn from normal donors showed the presence of certain bands that made WB results indeterminate such instance took us to search for HIV Ag in order to confirm an early seroconversion or possible cross reaction with another retrov


Platelets in HIV-infection: decrease associated with immunodeficiency, mycobacteriae infection and salmonellae septicemia: pseudothrombocytopenia in HIV-infection.
Int Conf AIDS 1989 Jun 4-9; 5:483 (abstract no. B.516)
Matuschke A, Heinrich B, Welzl G, Bogner JR, Fuebetal H, Goebel FD; Univers. Munchen, Med. Poliklinik, FRG
To describe different events associated with platelet reduction in HIV-infection. Classification of immunodeficiency according to Walter Reed Classification System (WR 1-6). Documentation of the first platelet count/mul (PL) at admission, after progression in WR, after developing an opportunistic in


Evaluation of HIV-antibodies in samples of commercial preparations of gamma globulin for parenteral use in the periods 1973-1981 and 1984-1986.
Int Conf AIDS 1989 Jun 4-9; 5:483 (abstract no. B.517)
Tinelli M, Cattaneo E, Achilli G; Institute of Infectious Diseases, IRCCS - Policlinico S. Matteo, Pavia, Italy
Evaluation of the presence of HIV-antibodies in gamma globulin different commercial preparations in the periods 1973-1981 and l984-1986. Samples have been screened by ELISA commercial kits and, if positive, confirmed by homemade Western-blot. In period 1973-1981 we tested 13 gamma globulin


Correlation of the HIV and HTLVI antibody, HIV antigen in haematological disease (H.D.).
Int Conf AIDS 1989 Jun 4-9; 5:483 (abstract no. B.518)
Granati L, Mandelli F, Isacchi G, De Rossi G, Titti M, Pezzella M; Haematological Section-Human Biopathology Departments Infectious Disease Chair, University of Rome, Instituto Superiore di Sanita, Roma
To investigate the prevalence, the correlation and the follow up of HIV antibody, HIV antigen, HTLVI antibody in H.D., to investigate the significance of indeterminate western blot. During 1988, 1400 patients with H.D. were tested by ELISA (Organon) for HIV antibody (if positive W.B. was performed),


Extrapulmonary cryptococcal disease as a manifestation of AIDS in Louisiana.
Int Conf AIDS 1989 Jun 4-9; 5:484 (abstract no. B.519)
Atkinson W, Troxler S, McFarland L; Louisiana Department of Health and Hospitals, New Orleans, LA, USA
To determine the frequency and characteristics of patients with extrapulmonary cryptococcosis (EC) as a manifestation of AIDS in Louisiana (LA) residents between 1981 and December 1988. Cases of AIDS were identified by an active hospital-based surveillance system. Only definitively diagnosed cases m


[Infection by HIV, after a liver transplant: study of 2 patients for 2 years]
Int Conf AIDS 1989 Jun 4-9; 5:484 (abstract no. B.520)
Vanhems P, Bresson-Hadni S, Vuitton D, Lab M, Miguet JP; Centre Hospitalier et Universitaire, 25030 Besancon, France
Is entamoeba histolytica in homosexual men a pathogen?
Int Conf AIDS 1989 Jun 4-9; 5:484 (abstract no. B.521)
Weinke T, Friedrich - Janicke B, Janitschke K; Universitatsklinikum Rudolf Virchow, Freie Universitat Berlin, West Germany
Entamoeba histolytica occurs frequently among sexually active homosexual men. We tried to evaluate the clinical importance of this protozoa. 320 male homosexuals were screened for intestinal parasites. E. histolytica was cultured in Robinson medium and positive cultures were classified into zymodeme


Spontaneous bacterial peritonitis and AIDS.
Int Conf AIDS 1989 Jun 4-9; 5:484 (abstract no. B.522)
Biancalana ML, Mendes WS, Levi GC, Carvalho MC, Mendonca JS, Trevisanello C; Servico de Moletias Infecciosas, Hospital do Servidor Publico Estadual, So Paulo, Brazil
The authors relate a case of a 28-year-old white homosexual man with AIDS, who was being treated for Kaposi s sarcoma and toxoplasmic encephalitis during 7 months when he developed aqueous diarrhea, weakness an diffuse abdominal pain. The physical examination revealed poor general condition, anemia, dehydration, anasar


[Non-lithiasitic cholecystitis, stenosis of the papilla, sclerosing cholangitis and AIDS]
Int Conf AIDS 1989 Jun 4-9; 5:484 (abstract no. B.523)
Weinbreck P, Loustaud V, Valleix D, Mounier M, Denis F; Unite des Maladies Infectieuses - Chu Limoges - 87042 France
Spontaneous rupture of spleen in a HIV seropositive non- thrombocytopenic patient.
Int Conf AIDS 1989 Jun 4-9; 5:484 (abstract no. B.524)
Pesce A, Vinti H, Taillan B, Fuzibet JG, Dujardin P, Cassuto JP; Services de Medecine Interne I et II - Hopital de Cimiez - CHRU Nice, France
We recently observed a case of rupture of the spleen, in a HIV seropositive asymptomatic and non thrombocytopenic patient in relation with a large spontaneous splenic hematoma. A 25-year- old male patient, intravenous drug abuser from 1982 to 1984, HIV seropositive since February 1986 and regularly followed without any


The prevalence of the hepatitis B virus (HBV) markers in patients who are carriers of anti-HIV in Sao Paulo, Brazil.
Int Conf AIDS 1989 Jun 4-9; 5:485 (abstract no. B.525)
Diaz RS, Silva AE, Ferraz ML, Sader HS, Castilho MP, Lewi DS; Escola Paulista de Medicina, Sao Paulo, Brazil
To study the behaviour of VHB infection in patients who are carriers of HIV, separated into two distinct groups evaluated in different times. The two groups were compared between themselves and with a control group of blood donors from a blood bank. MATERIAL AND The patients were divided into two gr


Seroprevalence and clinical correlates of herpes simplex virus (HSV) antibody in 41 AIDS patients.
Int Conf AIDS 1989 Jun 4-9; 5:485 (abstract no. B.526)
Safrin S, Houlihan C, Arvin A, Mills J; San Francisco General Hospital, University of California, CA, USA
(1) To assess the clinical course of mucocutaneous HSV in patients with AIDS; (2) To determine the seroprevalence of HSV antibody in this cohort; (3) To analyze the correlation of the presence of serum HSV antibody with clinical herpetic disease activity. Forty-one patients with the diagnosis of fir


Diseases other than AIDS among IV drug users.
Int Conf AIDS 1989 Jun 4-9; 5:485 (abstract no. B.527)
Trapido EJ, McCoy CB, Chitwood DD, McCoy HV, Inciardi JA; University of Miami Medical School, Miami, FL, USA
To describe the distribution of diseases other than AIDS among a cohort of IV drug users. As part of a study which tests two interventions to reduce the risk of AIDS among IVDUs, 346 subjects were recruited from drug networks, tested for HIV-1 positivity, and interviewed. Bivariate analyses were per


Increased incidence of M. kansasii infection due to AIDS and HIV infection at Cook County Hospital, Chicago.
Int Conf AIDS 1989 Jun 4-9; 5:485 (abstract no. B.529)
Sherer R, Kocka F, Muthuswamy P, Pulvirenti J, Blair S, Sonnenberg M; Department of Medicine, Cook County Hospital, Chicago, IL, USA
To compare the incidence of M. kansasii infection at Cook County Hospital (CCH) from 1977-1982 and 1983-1988, and to evaluate the significance of associated AIDS and HIV infection. All patients with M. kansasii infection between 1977 and 11/88 were cross-referenced with all persons with AIDS and HIV


The Koebner phenomenon in AIDS-related Kaposi's sarcoma.
Int Conf AIDS 1989 Jun 4-9; 5:485 (abstract no. B.530)
Janier M, Baccard M, Cabotin PP, Timsit F, Colonna A, Morel P; Centre Clinique et Biologique des MST, Hopital Saint-Louis, Paris, France
The Koebner phenomenon is the development of isomorphic lesions in the traumatized normal skin of patients who have psoriasis, lichen planus or various cutaneous diseases. Kaposi s sarcoma (KS) in its classical form sometimes koebnerizes. We have observed 4 cases of Koebner phenomenon in the course of AIDS-related KS.


Ano-rectal surgery of AIDS patients.
Int Conf AIDS 1989 Jun 4-9; 5:486 (abstract no. B.531)
Fraga LF, Bravo FP, Paulo FL, Quinhoes EP, Rachid MC; Gaffree & Guinle University Hospital - University of Rio de Janeiro - Brazil
To discuss the importance of proctologic surgical procedures for HIV infected patients. During 1987 and 1988 we operated 20 HIV infected patients of groups II, III and IV of CDC criteria. All patients were tested for HIV antibodies by ELISA, Indirect Immunofluorescence and/or Western blot.


Radiographic patterns of pulmonary tuberculosis among AIDS patients in Rio de Janeiro, Brazil.
Int Conf AIDS 1989 Jun 4-9; 5:486 (abstract no. B.532)
Eyer-Silva W, Graca MH, Camara CS, Teixeira E, Sion FS, Morais de Sa CA; Gaffree & Guinle University Hospital - University of Rio de Janeiro (UNI-RIO) - Brazil
Describe roenotgenographic features of pulmonary tuberculosis among Brazilian AIDS patients. We reviewed standard chest radiographs of 42 patients who met the current CDC criteria for AIDS and who also had a diagnosis of pulmonary tuberculosis. Among 42 patients reviewed, 41 were men and 1


Echocardiographic (ECHO) findings in HIV infected patients.
Int Conf AIDS 1989 Jun 4-9; 5:486 (abstract no. B.533)
Talberg J, Morais de Sa CA, Cantisano AL, Oliveira DP, Sion FS, Rubini NPM; Gaffree & Guinle University Hospital, University of Rio de Janeiro, Brazil
To study echocardiographic findings in patients infected by HIV, groups III and IV (C.D.C.), from the out-patients unit and from in-patients of the HUGG, related to the period from August 85 to November 88. Parameters of dimensions, structures movements and cardiac functions were obtained by ECHO in


Cardiologic findings in autopsies of AIDS patients.
Int Conf AIDS 1989 Jun 4-9; 5:486 (abstract no. B.534)
Talberg J, Morais de Sa CA, Oliveira CA, Signorine DJ, Graca MH, Ismael C; Gaffree & Guinle University Hospital - University of Rio de Janeiro (UNI-RIO) - Brazil
To study the cardiologic findings in autopsies of AIDS patients performed at the Department of Pathology, Gaffree & Guinle University Hospital. We studied the cardiologic findings in the autopsies of 33 AIDS patients classified individually and per cardiac segment (pericardium, myocardium and en


[Value of synthetic peptides specific for HIV1-HIV2 in blood specimens from Abidjan]
Int Conf AIDS 1989 Jun 4-9; 5:486 (abstract no. B.535)
Gueguen M, Abissey S, Ruffault A, Guisth'Au O, Yao T, Genetet B; CRTS, CHU, Abidjan, Cote d'Ivoire
Evaluation of a rapid membrane based assay (HIV CHEK) for detection of antibody to HIV in serum samples from Nairobi.
Int Conf AIDS 1989 Jun 4-9; 5:486 (abstract no. B.536)
Moss GB, Maitha G, Plummer FA, Wamola IA, Ndinya-Achola JO, Kreiss JK; Univ. Nairobi, Kenya; Univ. Washington, Seattle, WA, USA
To evaluate a rapid membrane based HIV antibody assay. Serum obtained from various Nairobi clinics where HIV studies are being performed were tested for HIV antibody by ELISA and a rapid membrane based assay (RA) (HIV CHEK, Dupont). Western blots (WB) were performed on samples positive on either ass


Serum LDH isoenzyme activity in HIV patients with respiratory disease.
Int Conf AIDS 1989 Jun 4-9; 5:487 (abstract no. B.537)
Young M, McPherson R, Podlasek S, Pierce P; Georgetown University Hospital, Washington, DC, USA
To characterize the serum LDH isoenzyme pattern in HIV patients with elevated LDH and bronchoscopically diagnosed PCP or non-PCP respiratory pathogens. 14 HIV pts presenting with fever, cough, SOB or retenographic findings had serum LDH activity and isoenzyme analysis within 24 hours of bronchoscopy


Monitoring for HIV-1, HIV-2, HTLV-I sero-progression and sero-conversion.
Int Conf AIDS 1989 Jun 4-9; 5:487 (abstract no. B.538)
Constantine N, Fox E, Rodier G, Abbatte E; US Naval Medical Research Unit No. 3 (A WHO Collaborating Center for AIDS), Cairo, Egypt
To serologically monitor individuals whose sera had previously exhibited reactivity by at least one of seven retroviral screening assays, for sero-progression and sero-conversion for HIV-1, HIV-2, and HTLV-I. Sera from 33 high risk individuals in Djibouti were collected and re-examined after four mo


Eplblot-HIV Western blot as supplemental assay in testing HIV infection.
Int Conf AIDS 1989 Jun 4-9; 5:487 (abstract no. B.539)
Kaltwasser G, Streeter M, Quero S, Montiel F; Catholic University of Chile, Faculty of Medicine, Laboratory of Clinical Microbiology-CEDIUC, Chile
We evaluated the EPlblot-HIV Western blot from Epitope Inc., Beaverton, Oregon USA as supplemental test for serum samples from patients suspicious of HIV infection. This Western blot test was used in a total of serum 70 samples: 65 were from patients whose EIA screening tests gave repeatedly positive results; 5 samples


Increased ADA activity in children with perinatal HIV infection.
Int Conf AIDS 1989 Jun 4-9; 5:487 (abstract no. B.540)
Palomba E, David O, Gabiano C, Tovo PA; Instituto di Clinica Pediatrica, Universita' di Torino, Torino, Italy
To evaluate whether adenosine deaminase (ADA) activity is enhanced in erythrocytes of children with perinatal HIV infection and its possible prognostic significance. ADA was assessed, according to Hopkinson s method in RBC of 33 children born from HIV + mothers (8 P2, 13 P1, 12 PO) and in a control


[Quantitative Western blot: it's value in surveillance of HIV seropositive patients]
Int Conf AIDS 1989 Jun 4-9; 5:487 (abstract no. B.541)
Schiavini D, Puel J; Laboratoire de Virologie, CHU Purpan, Toulouse, France
Model system in HIV-antibody testing for Boehringer Mannheim Enzymun-Test diagnostics.
Int Conf AIDS 1989 Jun 4-9; 5:487 (abstract no. B.542)
Bayer H, Lin M, Klein C, Kirch P; Boehringer Mannheim GmbH, Forschungszentrum, D-8132 Tutzing, FRG
Screening tests have to be sensitive for possibly all specificities of HIV-antibodies, while specific antibody tests are important for prognosis of diseases (p24) or distinguishing HIV-I from HIV-II-infection. For our automatic Boehringer Mannheim Enzymun-Test-System we developed a model-system using a single universal


OKT4 epitope deficiency and symptomatic immune impairment mimicking aids.
Int Conf AIDS 1989 Jun 4-9; 5:488 (abstract no. B.543)
Van de Perre P, Lepage P; Programme National de Lutte contre le SIDA, Kigali, Rwanda
CASE REPORT: The patient was a 14-year old girl presenting with disseminated cutaneous candidiasis , severe pain on left foot and persistent diarrhea. A X-ray film of the left foot revealed an osteitis lesion of the calcaneum suggestive of tuberculosis . Massive infestation of stool samples by Giardia lamblia was di


Peripheral blood lymphocytes (PBL) forming rosettes with their autologous erythrocytes (AE)-(AELFR) in HIV infected patients.
Int Conf AIDS 1989 Jun 4-9; 5:488 (abstract no. B.544)
Pathouli C, Spiliotopoulou J, Kontopoulou-Griva I; Athens University, Athens, Greece
We observed that a small part of normal PBL 8-14% forms spontaneous rosettes (R) with their AE in Man. We wanted to investigate this phenomenon in individuals infected by HIV. We studied 23 Hemophiliacs positive for HIV and 22 individuals infected by HIV and/or suffering from AIDS. PBL were separate


Multidisciplinary approach to HIV seropositive patients; a two year experience of an out-patient department.
Int Conf AIDS 1989 Jun 4-9; 5:488 (abstract no. B.545)
Barbarini G, Maccabruni A, Malfitano A, Calderon W, Parisi A, Tacconi F; Clinic of Infectious Diseases, IRCCS S. Matteo, University of Pavia, Italy
To give a complete response to increasing needs of HIV seropositive subjects. Since 1986 in the Clinic of Infectious Disease of Pavia, a special out-come patients department was established for ambulatory management of HIV infected subjects. In this structure are always present an infectivologist, a


[A rare cause of diarrhea in an HIV positive patient]
Int Conf AIDS 1989 Jun 4-9; 5:488 (abstract no. B.546)
Annick D, Similowski T, Rosenheim M, Katlama C, Fassin D, Gentilini M; Dpt de Sante Publique, Parasitologie et Medecine Tropicale et Unite INSERM 313, Paris, France
Multiplication of HHV-6 and HIV1 in blood lymphocyte culture.
Int Conf AIDS 1989 Jun 4-9; 5:488 (abstract no. B.547)
Agut H, Kerouedan D, M'Pele P, Collandre H, Rosenheim M, Huraux JM; Laboratoire de Bacteriologie-Virologie, Hopital de la Pitie-Salpetriere, Paris, France
To detect the simultaneous multiplication of HIV and human herpes virus-6 (HHV-6) in primary lymphocyte culture from patient s blood. Peripheral blood mononuclear cells (PBMC) were grown in primary culture according to conventional procedures. Secondary cultures were performed with freshly stimulate


A synthetic peptide ELISA for detection of antibodies to HIV1.
Int Conf AIDS 1989 Jun 4-9; 5:488 (abstract no. B.548)
Libonatti O, Torstensson R, Mhalu S, Biberfeld G, Wigzell H; Karolinska Institute, Stockholm, Sweden
To synthesize and evaluate a peptide to be used in a diagnostic immunoassay. Hydrophilicity and the presence of two cysteines in close proximity were determinants to select a conserved sequence among different isolates of HIV1 derived from the transmembrane glycoprotein gp41. A twelve aminoacid pept


Concordance of polymerase chain reaction (PCR) with HIV antibody (Ab) in HIV infection.
Int Conf AIDS 1989 Jun 4-9; 5:489 (abstract no. B.549)
Horsburgh CR, Ou CY, Jason J, Holmberg S, Evatt B, Jaffe H; AIDS Program, CDC, Atlanta, GA, USA
To evaluate the correlation of PCR detection of HIV DNA and detection of HIV Ab. We examined peripheral blood mononuclear cells (PBMC) and serum from 112 homosexual men, 85 hemophilic men, 30 HIV-infected transfusion recipients, and 91 heterosexual partners of HIV-infected persons in 5 prospective s


A retrospective analysis of diseases associated with indeterminate HIV Western blot patterns.
Int Conf AIDS 1989 Jun 4-9; 5:489 (abstract no. B.550)
Drabick JJ, Horning L, Lennox J, Coyne P, Knight R, Dillard T, Burke D, Fuller S, Damato J; Walter Reed Army Medical Center, Washington, DC, USA
Some individuals possess antibodies reactive to HIV Western blot proteins in patterns not diagnostic of HIV infection. A retrospective chart review of patients exhibiting such antibodies was performed and compared to a control cohort of sex and age matched individuals from the same base population of HIV-negative blots


Etiology of indeterminate HIV Western blots.
Int Conf AIDS 1989 Jun 4-9; 5:489 (abstract no. B.551)
Celum C, Coombs RW, Lafferty WE, Egan R, Sninsky J, Holmes KK; Univ of Washington, WA, USA
OBJECTIVES: To ascertain the etiologies of indeterminate HIV Western blots (IWB), the rates of seroconversion and sexual transmission, and the yield of supplemental HIV diagnostic tests. Thirty-seven individuals with positive HIV ELISAs and IWB and their current sexual partners were enrolled from diverse HIV t


Use of vitreous humour of the eye for HIV antibody tests of medicolegal autopsies.
Int Conf AIDS 1989 Jun 4-9; 5:489 (abstract no. B.552)
Kantanen ML, Brummer-Korvenkontio H, Karhunen PJ, Penttila A, Leinikki P; National Public Health Institute and Department of Forensic Medicine, University of Helsinki, Helsinki, Finland